{"id":"https://openalex.org/W4405491740","doi":"https://doi.org/10.1109/embc53108.2024.10781790","title":"Single-Wavelength Laminar Optical Tomography for In Vivo Microvascular Three-Dimensional Imaging","display_name":"Single-Wavelength Laminar Optical Tomography for In Vivo Microvascular Three-Dimensional Imaging","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405491740","doi":"https://doi.org/10.1109/embc53108.2024.10781790","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039915"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10781790","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10781790","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105773845","display_name":"H. Cui","orcid":"https://orcid.org/0000-0002-9923-1313"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Han Cui","raw_affiliation_strings":["Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107209855","display_name":"Dawei Han","orcid":"https://orcid.org/0000-0002-9294-373X"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dewei Han","raw_affiliation_strings":["Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101544039","display_name":"Wenquan Liu","orcid":"https://orcid.org/0000-0001-6728-9038"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenquan Liu","raw_affiliation_strings":["Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071116279","display_name":"Xinping Deng","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinping Deng","raw_affiliation_strings":["Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhixuan Xin","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhixuan Xin","raw_affiliation_strings":["Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100636088","display_name":"Guanglin Li","orcid":"https://orcid.org/0000-0001-9016-2617"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guanglin Li","raw_affiliation_strings":["Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences (CAS),CAS Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institute of Advanced Technology,Shenzhen,China","institution_ids":["https://openalex.org/I4210145761","https://openalex.org/I19820366"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5105773845"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.21023544,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.98089998960495,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laminar-flow","display_name":"Laminar flow","score":0.694210946559906},{"id":"https://openalex.org/keywords/tomography","display_name":"Tomography","score":0.6436736583709717},{"id":"https://openalex.org/keywords/optical-tomography","display_name":"Optical tomography","score":0.6384127140045166},{"id":"https://openalex.org/keywords/preclinical-imaging","display_name":"Preclinical imaging","score":0.5799153447151184},{"id":"https://openalex.org/keywords/optical-imaging","display_name":"Optical imaging","score":0.5792874693870544},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.5487778782844543},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5470371246337891},{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.5078867077827454},{"id":"https://openalex.org/keywords/wavelength","display_name":"Wavelength","score":0.48550891876220703},{"id":"https://openalex.org/keywords/optical-coherence-tomography","display_name":"Optical coherence tomography","score":0.4624500572681427},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.4009019136428833},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.2624255418777466},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.21939238905906677},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15714555978775024},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.07538801431655884}],"concepts":[{"id":"https://openalex.org/C76563973","wikidata":"https://www.wikidata.org/wiki/Q189452","display_name":"Laminar flow","level":2,"score":0.694210946559906},{"id":"https://openalex.org/C163716698","wikidata":"https://www.wikidata.org/wiki/Q841267","display_name":"Tomography","level":2,"score":0.6436736583709717},{"id":"https://openalex.org/C2777413408","wikidata":"https://www.wikidata.org/wiki/Q1968843","display_name":"Optical tomography","level":3,"score":0.6384127140045166},{"id":"https://openalex.org/C29331040","wikidata":"https://www.wikidata.org/wiki/Q7239554","display_name":"Preclinical imaging","level":3,"score":0.5799153447151184},{"id":"https://openalex.org/C92630104","wikidata":"https://www.wikidata.org/wiki/Q4115103","display_name":"Optical imaging","level":2,"score":0.5792874693870544},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.5487778782844543},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5470371246337891},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5078867077827454},{"id":"https://openalex.org/C6260449","wikidata":"https://www.wikidata.org/wiki/Q41364","display_name":"Wavelength","level":2,"score":0.48550891876220703},{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.4624500572681427},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.4009019136428833},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.2624255418777466},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.21939238905906677},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15714555978775024},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07538801431655884},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004423","descriptor_name":"Ear","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D004423","descriptor_name":"Ear","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041622","descriptor_name":"Tomography, Optical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc53108.2024.10781790","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10781790","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039915","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039915","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320337504","display_name":"Research and Development","ror":"https://ror.org/027s68j25"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1966956969","https://openalex.org/W1977349774","https://openalex.org/W1985617115","https://openalex.org/W1995913833","https://openalex.org/W2018553165","https://openalex.org/W2021473911","https://openalex.org/W2030545521","https://openalex.org/W2159093687","https://openalex.org/W2508711166","https://openalex.org/W2959830553","https://openalex.org/W2994917222","https://openalex.org/W3033973870","https://openalex.org/W3128131189","https://openalex.org/W6636871593"],"related_works":["https://openalex.org/W2166934110","https://openalex.org/W3011589137","https://openalex.org/W2233357049","https://openalex.org/W2028558083","https://openalex.org/W3200823469","https://openalex.org/W2552880441","https://openalex.org/W4243203305","https://openalex.org/W2636423659","https://openalex.org/W999530941","https://openalex.org/W2089574289"],"abstract_inverted_index":{"Laminar":[0],"Optical":[1],"Tomography":[2],"(LOT)":[3],"is":[4,83],"a":[5,25,31,70,87],"promising":[6],"non-invasive":[7],"technique":[8],"for":[9,51,120,128],"three-dimensional":[10,88],"imaging":[11],"of":[12,46,77,90,108],"complex":[13],"biological":[14],"structures,":[15],"combining":[16],"high":[17],"resolution":[18],"and":[19,93,123,133],"deep":[20],"penetration.":[21],"In":[22],"this":[23,49],"study,":[24],"LOT":[26,117],"system":[27,55],"was":[28],"assembled":[29],"using":[30],"520nm":[32],"continuous-wave":[33],"laser,":[34],"exploiting":[35],"the":[36,41,61,81,99,113],"contrast":[37],"mechanism":[38],"provided":[39],"by":[40],"unique":[42],"optical":[43],"absorption":[44],"coefficient":[45],"hemoglobin":[47],"at":[48],"wavelength":[50],"microvascular":[52,131],"imaging.":[53],"The":[54,74,115],"utilizes":[56],"raster":[57],"scanning":[58],"to":[59,85,102],"illuminate":[60],"target":[62],"tissue's":[63],"surface,":[64],"capturing":[65],"backscattered":[66],"light":[67,78],"intensity":[68],"with":[69,106],"multi-channel":[71],"Photomultiplier":[72],"Tubes.":[73],"inverse":[75],"problem":[76],"propagation":[79],"within":[80,112],"tissue":[82],"solved":[84],"reconstruct":[86],"image":[89,103],"microvasculature.":[91],"Phantom":[92],"in-vivo":[94],"rat":[95],"ear":[96],"results":[97],"demonstrate":[98],"system's":[100],"ability":[101],"micro":[104],"vessels":[105],"diameters":[107],"several":[109],"hundred":[110],"micrometers":[111],"tissue.":[114],"implemented":[116],"system,":[118],"known":[119],"its":[121,126],"simplicity":[122],"cost-effectiveness,":[124],"showcases":[125],"potential":[127],"applications":[129],"in":[130],"physiological":[132],"pathological":[134],"research,":[135],"as":[136,138],"well":[137],"clinical":[139],"diagnostics.":[140]},"counts_by_year":[],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}