{"id":"https://openalex.org/W4405491354","doi":"https://doi.org/10.1109/embc53108.2024.10781601","title":"Characterizing the Effect of Hold-Down Pressure for Local and Regional Stiffness Markers","display_name":"Characterizing the Effect of Hold-Down Pressure for Local and Regional Stiffness Markers","publication_year":2024,"publication_date":"2024-07-15","ids":{"openalex":"https://openalex.org/W4405491354","doi":"https://doi.org/10.1109/embc53108.2024.10781601","pmid":"https://pubmed.ncbi.nlm.nih.gov/40039030"},"language":"en","primary_location":{"id":"doi:10.1109/embc53108.2024.10781601","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10781601","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Smit Shah","orcid":null},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Smit Shah","raw_affiliation_strings":["Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105959023","display_name":"G Jaganathan","orcid":null},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jaganathan G","raw_affiliation_strings":["Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019952919","display_name":"Rahul Manoj","orcid":"https://orcid.org/0000-0001-5017-5018"},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rahul Manoj","raw_affiliation_strings":["Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103176855","display_name":"Raj Kiran","orcid":"https://orcid.org/0000-0002-0938-4026"},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]},{"id":"https://openalex.org/I4210102197","display_name":"Healthcare Technology Innovation Centre","ror":"https://ror.org/017mw4x28","country_code":"IN","type":"facility","lineage":["https://openalex.org/I4210102197"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Raj Kiran V","raw_affiliation_strings":["Indian Institute of Technology Madras,Healthcare Technology Innovation Centre,Chennai,600113"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Technology Madras,Healthcare Technology Innovation Centre,Chennai,600113","institution_ids":["https://openalex.org/I24676775","https://openalex.org/I4210102197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080462933","display_name":"P. M. Nabeel","orcid":"https://orcid.org/0000-0001-7280-0048"},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]},{"id":"https://openalex.org/I4210102197","display_name":"Healthcare Technology Innovation Centre","ror":"https://ror.org/017mw4x28","country_code":"IN","type":"facility","lineage":["https://openalex.org/I4210102197"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"P. M. Nabeel","raw_affiliation_strings":["Indian Institute of Technology Madras,Healthcare Technology Innovation Centre,Chennai,600113"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Technology Madras,Healthcare Technology Innovation Centre,Chennai,600113","institution_ids":["https://openalex.org/I24676775","https://openalex.org/I4210102197"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020295407","display_name":"Jayaraj Joseph","orcid":"https://orcid.org/0000-0002-7279-9099"},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jayaraj Joseph","raw_affiliation_strings":["Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Technology Madras,Department of Electrical Engineering,Chennai,600036","institution_ids":["https://openalex.org/I24676775"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2024","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11062","display_name":"Gear and Bearing Dynamics Analysis","score":0.9864000082015991,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stiffness","display_name":"Stiffness","score":0.5447787046432495},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.35050520300865173},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.18271198868751526},{"id":"https://openalex.org/keywords/structural-engineering","display_name":"Structural engineering","score":0.16646316647529602}],"concepts":[{"id":"https://openalex.org/C2779372316","wikidata":"https://www.wikidata.org/wiki/Q569057","display_name":"Stiffness","level":2,"score":0.5447787046432495},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35050520300865173},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.18271198868751526},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.16646316647529602}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059289","descriptor_name":"Vascular Stiffness","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D059289","descriptor_name":"Vascular Stiffness","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D059289","descriptor_name":"Vascular Stiffness","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc53108.2024.10781601","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc53108.2024.10781601","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:40039030","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40039030","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/13","display_name":"Climate action","score":0.7300000190734863}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1481607610","https://openalex.org/W2054448880","https://openalex.org/W2736466795","https://openalex.org/W2887579351","https://openalex.org/W2894836022","https://openalex.org/W2968919993","https://openalex.org/W2968955566","https://openalex.org/W3009459104","https://openalex.org/W3026347134","https://openalex.org/W3041355923","https://openalex.org/W4283320059"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Vascular":[0],"aging":[1],"occurs":[2],"due":[3,61],"to":[4,62,76,170,201],"pathologies":[5],"and":[6,14,43,56,86,92,115,154,157,177,181,183,194,229,251],"old":[7],"age.":[8],"Early":[9],"detection":[10],"of":[11,30,35,49,80,129,150,189,197,205,222,240],"stiffness":[12,36,94,230],"markers":[13,37],"arterial":[15],"geometry":[16],"parameters":[17],"in":[18,59,243],"the":[19,28,78,124,134,139,172,195,203,206,220,235,238,241,249],"carotid":[20,127,175,227],"artery":[21,128],"serves":[22],"as":[23],"an":[24,112],"essential":[25],"indicator":[26],"for":[27],"progression":[29],"vascular":[31],"aging.":[32],"The":[33,186,208,215],"assessment":[34],"is":[38],"typically":[39],"conducted":[40,145],"using":[41],"ultrasound":[42,113,119],"tonometer-based":[44],"devices.":[45],"However,":[46],"both":[47],"types":[48],"devices":[50],"present":[51],"challenges,":[52],"requiring":[53],"skilled":[54],"operators":[55,68],"exhibiting":[57],"variability":[58],"results":[60,216,250],"different":[63,67],"hold-down":[64,81,136,147,223,254],"pressures":[65],"when":[66],"are":[69],"involved.":[70],"In":[71],"this":[72,99,244],"study,":[73],"we":[74,101],"aim":[75],"quantify":[77],"impact":[79,221],"pressure":[82,137,148,224,255],"on":[83,90,123,138,225],"diameter-based":[84],"measurements":[85,242],"evaluate":[87],"its":[88],"effects":[89],"local":[91,182],"regional":[93,184],"markers.":[95],"To":[96],"carry":[97],"out":[98],"investigation,":[100],"utilized":[102],"ARTSENS":[103,163],"Plus":[104,164],"device":[105],"along":[106],"with":[107],"a":[108,116],"multi-modal":[109],"probe":[110],"comprising":[111],"transducer":[114],"tonometer.":[117],"A-mode":[118],"scanning":[120],"was":[121,192,199],"performed":[122],"left":[125],"common":[126],"each":[130],"participant,":[131],"tonometer":[132],"indicated":[133],"applied":[135,169],"participant's":[140],"skin.":[141],"Four":[142],"trials":[143],"were":[144,161,168],"at":[146],"levels":[149],"50,":[151],"100,":[152],"150,":[153],"200":[155],"mmHg,":[156],"RF":[158],"echo":[159],"frames":[160],"recorded.":[162],"signal":[165],"processing":[166],"algorithms":[167],"obtain":[171],"recorded":[173],"frames'":[174],"diameter":[176,190],"pressure,":[178,180,228],"central":[179],"stiffness.":[185],"beat-to-beat":[187],"repeatability":[188],"values":[191],"examined,":[193],"coefficient":[196],"variation":[198],"calculated":[200],"assess":[202],"consistency":[204],"measurements.":[207],"system's":[209],"signal-to-noise":[210],"ratio":[211],"exceeded":[212],"25":[213],"dB.":[214],"section":[217],"delves":[218],"into":[219,234],"diameter,":[226],"markers,":[231],"providing":[232],"insights":[233],"variables":[236],"influencing":[237],"reliability":[239],"cardiovascular":[245],"assessment.":[246],"From":[247],"all":[248],"observations":[252],"optimal":[253],"can":[256],"be":[257],"slightly":[258],"higher":[259],"than":[260],"diastolic":[261],"pressure.":[262]},"counts_by_year":[],"updated_date":"2026-07-28T07:46:37.118299","created_date":"2025-10-10T00:00:00"}