{"id":"https://openalex.org/W4294975573","doi":"https://doi.org/10.1109/embc48229.2022.9872001","title":"Towards non-wettable neural electrodes for a minimized foreign body reaction","display_name":"Towards non-wettable neural electrodes for a minimized foreign body reaction","publication_year":2022,"publication_date":"2022-07-11","ids":{"openalex":"https://openalex.org/W4294975573","doi":"https://doi.org/10.1109/embc48229.2022.9872001","pmid":"https://pubmed.ncbi.nlm.nih.gov/36086668"},"language":"en","primary_location":{"id":"doi:10.1109/embc48229.2022.9872001","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc48229.2022.9872001","pdf_url":null,"source":{"id":"https://openalex.org/S4363607706","display_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035167243","display_name":"Danesh Ashouri Vajari","orcid":"https://orcid.org/0000-0002-6206-6756"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Danesh Ashouri Vajari","raw_affiliation_strings":["Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019048511","display_name":"Ali Sharbatian","orcid":"https://orcid.org/0000-0001-9531-4026"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ali Sharbatian","raw_affiliation_strings":["Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003281023","display_name":"Kalyani Devkota","orcid":null},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kalyani Devkota","raw_affiliation_strings":["Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058067206","display_name":"Thomas Stieglitz","orcid":"https://orcid.org/0000-0002-7349-4254"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Stieglitz","raw_affiliation_strings":["Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Univ. of Freiburg,Laboratory for Biomedical Microtechnology,Dept. of Microsystems Engineering - IMTEK,Germany","institution_ids":["https://openalex.org/I161046081"]},{"raw_affiliation_string":"Dept. of Microsystems Engineering - IMTEK, Laboratory for Biomedical Microtechnology, Univ. of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5035167243"],"corresponding_institution_ids":["https://openalex.org/I161046081"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.15584416,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":null,"first_page":"3919","last_page":"3922"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9621000289916992,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10783","display_name":"Additive Manufacturing and 3D Printing Technologies","score":0.9539999961853027,"subfield":{"id":"https://openalex.org/subfields/2203","display_name":"Automotive Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wetting","display_name":"Wetting","score":0.7002522349357605},{"id":"https://openalex.org/keywords/fabrication","display_name":"Fabrication","score":0.6970622539520264},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6587614417076111},{"id":"https://openalex.org/keywords/implant","display_name":"Implant","score":0.5026068687438965},{"id":"https://openalex.org/keywords/contact-angle","display_name":"Contact angle","score":0.4936414957046509},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.49306485056877136},{"id":"https://openalex.org/keywords/microstructure","display_name":"Microstructure","score":0.47062018513679504},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.46338900923728943},{"id":"https://openalex.org/keywords/foreign-body","display_name":"Foreign body","score":0.44426289200782776},{"id":"https://openalex.org/keywords/reentrancy","display_name":"Reentrancy","score":0.41128775477409363},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.345700204372406},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.34382355213165283},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.3034313917160034},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.13087603449821472},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.11436682939529419},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.08532664179801941},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.08526790142059326}],"concepts":[{"id":"https://openalex.org/C134514944","wikidata":"https://www.wikidata.org/wiki/Q817136","display_name":"Wetting","level":2,"score":0.7002522349357605},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.6970622539520264},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6587614417076111},{"id":"https://openalex.org/C2781411149","wikidata":"https://www.wikidata.org/wiki/Q486975","display_name":"Implant","level":2,"score":0.5026068687438965},{"id":"https://openalex.org/C6556556","wikidata":"https://www.wikidata.org/wiki/Q899239","display_name":"Contact angle","level":2,"score":0.4936414957046509},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.49306485056877136},{"id":"https://openalex.org/C87976508","wikidata":"https://www.wikidata.org/wiki/Q1498213","display_name":"Microstructure","level":2,"score":0.47062018513679504},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.46338900923728943},{"id":"https://openalex.org/C2779995113","wikidata":"https://www.wikidata.org/wiki/Q1455142","display_name":"Foreign body","level":2,"score":0.44426289200782776},{"id":"https://openalex.org/C161406801","wikidata":"https://www.wikidata.org/wiki/Q963635","display_name":"Reentrancy","level":2,"score":0.41128775477409363},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.345700204372406},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.34382355213165283},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.3034313917160034},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.13087603449821472},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11436682939529419},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08532664179801941},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.08526790142059326},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005549","descriptor_name":"Foreign-Body Reaction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005549","descriptor_name":"Foreign-Body Reaction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005549","descriptor_name":"Foreign-Body Reaction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc48229.2022.9872001","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc48229.2022.9872001","pdf_url":null,"source":{"id":"https://openalex.org/S4363607706","display_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:36086668","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36086668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education","score":0.6399999856948853}],"awards":[{"id":"https://openalex.org/G5374188541","display_name":null,"funder_award_id":"EXC 1086","funder_id":"https://openalex.org/F4320308022","funder_display_name":"California Department of Fish and Game"}],"funders":[{"id":"https://openalex.org/F4320308022","display_name":"California Department of Fish and Game","ror":"https://ror.org/02v6w2r95"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W2183481258","https://openalex.org/W2762541380","https://openalex.org/W2765656753","https://openalex.org/W3025246997","https://openalex.org/W3154658958","https://openalex.org/W3204319467"],"related_works":["https://openalex.org/W2928547925","https://openalex.org/W205077278","https://openalex.org/W3110121864","https://openalex.org/W2321855875","https://openalex.org/W2321743568","https://openalex.org/W2007634794","https://openalex.org/W2890620599","https://openalex.org/W2050440705","https://openalex.org/W2375596248","https://openalex.org/W2197898445"],"abstract_inverted_index":{"Functionality":[0],"of":[1,17,26,52,77,89,104,118,128,141],"neural":[2,97,120,142],"implants":[3],"can":[4,99],"be":[5],"seriously":[6],"impaired":[7],"by":[8,75,86],"scarring":[9],"during":[10],"the":[11,18,27,34,39,87,92,101,105,109,112,116,119,126,129,138],"foreign":[12,35],"body":[13,36,113],"reaction":[14,37],"(FBR).":[15],"Tailoring":[16],"material-tissue":[19],"interface":[20,98],"is":[21],"supposed":[22],"to":[23],"modulate":[24,33],"part":[25],"FBR.":[28],"Surface":[29],"structures":[30],"might":[31],"physically":[32],"in":[38,96,136],"acute":[40],"phase":[41],"directly":[42],"after":[43],"implantation.":[44],"This":[45],"work":[46],"focuses":[47],"on":[48],"fabrication":[49],"and":[50,72,81,133],"characterization":[51],"bioinspired":[53],"microtextures":[54],"comprising":[55],"reentrant":[56],"cavities":[57],"with":[58,115],"non-wettable":[59],"surface":[60,94,117],"characteristics.":[61],"The":[62],"Selected":[63],"microstructure":[64],"patterns":[65],"were":[66,73],"fabricated":[67],"using":[68],"direct":[69],"laser":[70],"writing":[71],"characterized":[74],"means":[76],"contact":[78],"angle":[79],"measurements":[80],"immersion":[82],"tests.":[83],"Clinical":[84],"Relevance-Suggested":[85],"outcome":[88],"this":[90],"study,":[91],"proposed":[93],"characteristics":[95],"impact":[100,127],"wetting":[102],"properties":[103],"interface,":[106],"hence,":[107],"influence":[108],"interaction":[110],"between":[111],"fluid":[114],"implant.":[121],"Future":[122],"studies":[123],"should":[124],"address":[125],"suggested":[130],"design":[131],"criterion":[132],"their":[134],"applicability":[135],"improving":[137],"long-term":[139],"stability":[140],"implants.":[143]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}