{"id":"https://openalex.org/W4294975409","doi":"https://doi.org/10.1109/embc48229.2022.9871728","title":"Multiscale partition-based Kolmogorov-Sinai Entropy: a preliminary HRV study on Heart Failure vs. Atrial Fibrillation","display_name":"Multiscale partition-based Kolmogorov-Sinai Entropy: a preliminary HRV study on Heart Failure vs. Atrial Fibrillation","publication_year":2022,"publication_date":"2022-07-11","ids":{"openalex":"https://openalex.org/W4294975409","doi":"https://doi.org/10.1109/embc48229.2022.9871728","pmid":"https://pubmed.ncbi.nlm.nih.gov/36085961"},"language":"en","primary_location":{"id":"doi:10.1109/embc48229.2022.9871728","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc48229.2022.9871728","pdf_url":null,"source":{"id":"https://openalex.org/S4363607706","display_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045184957","display_name":"Andrea Scarciglia","orcid":"https://orcid.org/0000-0003-3675-6160"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I1300504238","display_name":"Piaggio (Italy)","ror":"https://ror.org/00r254y42","country_code":"IT","type":"company","lineage":["https://openalex.org/I1300504238"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Scarciglia","raw_affiliation_strings":["School of Engineering, University of Pisa,Bioengineering and Robotics Research Center E.Piaggio,Department of Information Engineering,Italy","Department of Information Engineering, Bioengineering and Robotics Research Center E.Piaggio, School of Engineering, University of Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Engineering, University of Pisa,Bioengineering and Robotics Research Center E.Piaggio,Department of Information Engineering,Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]},{"raw_affiliation_string":"Department of Information Engineering, Bioengineering and Robotics Research Center E.Piaggio, School of Engineering, University of Pisa, Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013014934","display_name":"Vincenzo Catrambone","orcid":"https://orcid.org/0000-0001-9030-7601"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I1300504238","display_name":"Piaggio (Italy)","ror":"https://ror.org/00r254y42","country_code":"IT","type":"company","lineage":["https://openalex.org/I1300504238"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vincenzo Catrambone","raw_affiliation_strings":["School of Engineering, University of Pisa,Bioengineering and Robotics Research Center E.Piaggio,Department of Information Engineering,Italy","Department of Information Engineering, Bioengineering and Robotics Research Center E.Piaggio, School of Engineering, University of Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Engineering, University of Pisa,Bioengineering and Robotics Research Center E.Piaggio,Department of Information Engineering,Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]},{"raw_affiliation_string":"Department of Information Engineering, Bioengineering and Robotics Research Center E.Piaggio, School of Engineering, University of Pisa, Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102798845","display_name":"Claudio Bonanno","orcid":"https://orcid.org/0000-0002-1421-6510"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Claudio Bonanno","raw_affiliation_strings":["University of Pisa,2Department of Mathematics,Italy","2Department of Mathematics, University of Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pisa,2Department of Mathematics,Italy","institution_ids":["https://openalex.org/I108290504"]},{"raw_affiliation_string":"2Department of Mathematics, University of Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041459422","display_name":"Gaetano Valenza","orcid":"https://orcid.org/0000-0001-6574-1879"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I1300504238","display_name":"Piaggio (Italy)","ror":"https://ror.org/00r254y42","country_code":"IT","type":"company","lineage":["https://openalex.org/I1300504238"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gaetano Valenza","raw_affiliation_strings":["School of Engineering, University of Pisa,Bioengineering and Robotics Research Center E.Piaggio,Department of Information Engineering,Italy","Department of Information Engineering, Bioengineering and Robotics Research Center E.Piaggio, School of Engineering, University of Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Engineering, University of Pisa,Bioengineering and Robotics Research Center E.Piaggio,Department of Information Engineering,Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]},{"raw_affiliation_string":"Department of Information Engineering, Bioengineering and Robotics Research Center E.Piaggio, School of Engineering, University of Pisa, Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5874,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.54222973,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"101","issue":null,"first_page":"131","last_page":"134"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11270","display_name":"Complex Systems and Time Series Analysis","score":0.9886999726295471,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.9690999984741211,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"Heart rate variability","score":0.6158534288406372},{"id":"https://openalex.org/keywords/heart-failure","display_name":"Heart failure","score":0.6118635535240173},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"Atrial fibrillation","score":0.5861765742301941},{"id":"https://openalex.org/keywords/sample-entropy","display_name":"Sample entropy","score":0.5752767324447632},{"id":"https://openalex.org/keywords/entropy","display_name":"Entropy (arrow of time)","score":0.5550779700279236},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4289303421974182},{"id":"https://openalex.org/keywords/time-series","display_name":"Time series","score":0.3959653079509735},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.38190120458602905},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.37138038873672485},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3317972719669342},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3251052796840668},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.26727086305618286},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.186387300491333},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.08478590846061707},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.0790887176990509}],"concepts":[{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.6158534288406372},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6118635535240173},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.5861765742301941},{"id":"https://openalex.org/C66696666","wikidata":"https://www.wikidata.org/wiki/Q17105612","display_name":"Sample entropy","level":3,"score":0.5752767324447632},{"id":"https://openalex.org/C106301342","wikidata":"https://www.wikidata.org/wiki/Q4117933","display_name":"Entropy (arrow of time)","level":2,"score":0.5550779700279236},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4289303421974182},{"id":"https://openalex.org/C151406439","wikidata":"https://www.wikidata.org/wiki/Q186588","display_name":"Time series","level":2,"score":0.3959653079509735},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38190120458602905},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.37138038873672485},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3317972719669342},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3251052796840668},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.26727086305618286},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.186387300491333},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08478590846061707},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0790887176990509},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019277","descriptor_name":"Entropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019277","descriptor_name":"Entropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019277","descriptor_name":"Entropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc48229.2022.9871728","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc48229.2022.9871728","pdf_url":null,"source":{"id":"https://openalex.org/S4363607706","display_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:36085961","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36085961","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:arpi.unipi.it:11568/1151819","is_oa":false,"landing_page_url":"https://hdl.handle.net/11568/1151819","pdf_url":null,"source":{"id":"https://openalex.org/S4377196265","display_name":"CINECA IRIS Institutial research information system (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7400000095367432,"display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320317295","display_name":"Dipartimenti di Eccellenza","ror":null},{"id":"https://openalex.org/F4320321873","display_name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","ror":"https://ror.org/0166hxq48"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1553175645","https://openalex.org/W1862394037","https://openalex.org/W1929108078","https://openalex.org/W1964684355","https://openalex.org/W1964835817","https://openalex.org/W1986618283","https://openalex.org/W1999320110","https://openalex.org/W2026699230","https://openalex.org/W2053147468","https://openalex.org/W2053908484","https://openalex.org/W2058312364","https://openalex.org/W2059851411","https://openalex.org/W2077204677","https://openalex.org/W2077681639","https://openalex.org/W2093266575","https://openalex.org/W2127912154","https://openalex.org/W2144382181","https://openalex.org/W2153722516","https://openalex.org/W2162273778","https://openalex.org/W2162800060","https://openalex.org/W2171138447","https://openalex.org/W2399495722","https://openalex.org/W2590023122","https://openalex.org/W2744665246","https://openalex.org/W2961700468","https://openalex.org/W3209213334","https://openalex.org/W4213049026"],"related_works":["https://openalex.org/W2314914269","https://openalex.org/W2006708776","https://openalex.org/W112050585","https://openalex.org/W3088843374","https://openalex.org/W3082889039","https://openalex.org/W2946788172","https://openalex.org/W1976653534","https://openalex.org/W2142558988","https://openalex.org/W2062266966","https://openalex.org/W2022287597"],"abstract_inverted_index":{"Several":[0],"approaches":[1],"for":[2,40,142],"estimating":[3],"complexity":[4,30,144],"in":[5],"physiological":[6],"time":[7,11,116],"series":[8],"at":[9],"various":[10],"scales":[12,117],"have":[13,32],"recently":[14],"been":[15,33],"developed,":[16],"with":[17,101,109],"a":[18,35,139],"special":[19],"focus":[20],"on":[21,77],"heart":[22,103],"rate":[23],"variability":[24,148],"(HRV)":[25],"series.":[26,80,149],"While":[27],"numerous":[28],"multiscale":[29,36,72,133],"quantifiers":[31],"investigated,":[34],"Kolmogorov-Sinai":[37],"(K-S)":[38],"entropy":[39,76,136],"the":[41,58,131,143],"characterization":[42],"of":[43,146],"cardiovascular":[44,126,147],"dynamics":[45],"still":[46],"has":[47],"to":[48,70],"be":[49],"properly":[50],"assessed.":[51],"In":[52],"this":[53],"pilot":[54],"study,":[55],"we":[56],"investigate":[57],"Algorithmic":[59],"Information":[60],"Content,":[61],"which":[62],"is":[63],"calculated":[64],"using":[65],"an":[66],"effective":[67],"compression":[68],"algorithm,":[69],"quantify":[71],"partition-":[73],"based":[74],"K-S":[75,135],"experimental":[78],"HRV":[79],"Data":[81],"were":[82],"gathered":[83],"from":[84,92],"publicly":[85],"available":[86],"datasets":[87],"comprising":[88],"long-term,":[89],"unstructured":[90],"recordings":[91],"10":[93,99,107],"healthy":[94,123],"subjects,":[95],"as":[96,98],"well":[97],"patients":[100,108],"congestive":[102],"failure":[104],"(CHF)":[105],"and":[106,118],"atrial":[110],"fibrillation.":[111],"Results":[112],"show":[113],"that":[114,130],"multiple":[115],"domain":[119],"partitions":[120],"statistically":[121],"discern":[122],"vs.":[124],"pathological":[125],"dynamics.":[127],"We":[128],"conclude":[129],"proposed":[132],"partition-based":[134],"may":[137],"constitute":[138],"viable":[140],"tool":[141],"assessment":[145]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}