{"id":"https://openalex.org/W4200418018","doi":"https://doi.org/10.1109/embc46164.2021.9631095","title":"Brain Connectivity Analysis in Anesthetized and Awake States: an ECoG Study in Monkeys","display_name":"Brain Connectivity Analysis in Anesthetized and Awake States: an ECoG Study in Monkeys","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200418018","doi":"https://doi.org/10.1109/embc46164.2021.9631095","pmid":"https://pubmed.ncbi.nlm.nih.gov/34891252"},"language":"en","primary_location":{"id":"doi:10.1109/embc46164.2021.9631095","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9631095","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064498583","display_name":"Tianli Xie","orcid":"https://orcid.org/0000-0003-2378-2116"},"institutions":[{"id":"https://openalex.org/I196699116","display_name":"Wuhan University of Technology","ror":"https://ror.org/03fe7t173","country_code":"CN","type":"education","lineage":["https://openalex.org/I196699116"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Tianli Xie","raw_affiliation_strings":["Wuhan University of Technology, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"Wuhan University of Technology, Wuhan, China","institution_ids":["https://openalex.org/I196699116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100444463","display_name":"Kun Chen","orcid":"https://orcid.org/0000-0002-2188-1439"},"institutions":[{"id":"https://openalex.org/I196699116","display_name":"Wuhan University of Technology","ror":"https://ror.org/03fe7t173","country_code":"CN","type":"education","lineage":["https://openalex.org/I196699116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kun Chen","raw_affiliation_strings":["Wuhan University of Technology, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"Wuhan University of Technology, Wuhan, China","institution_ids":["https://openalex.org/I196699116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026385971","display_name":"Li Ma","orcid":"https://orcid.org/0000-0001-8167-7627"},"institutions":[{"id":"https://openalex.org/I196699116","display_name":"Wuhan University of Technology","ror":"https://ror.org/03fe7t173","country_code":"CN","type":"education","lineage":["https://openalex.org/I196699116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Ma","raw_affiliation_strings":["Wuhan University of Technology, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"Wuhan University of Technology, Wuhan, China","institution_ids":["https://openalex.org/I196699116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091654425","display_name":"Qingsong Ai","orcid":"https://orcid.org/0000-0003-4283-2289"},"institutions":[{"id":"https://openalex.org/I196699116","display_name":"Wuhan University of Technology","ror":"https://ror.org/03fe7t173","country_code":"CN","type":"education","lineage":["https://openalex.org/I196699116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingsong Ai","raw_affiliation_strings":["Wuhan University of Technology, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"Wuhan University of Technology, Wuhan, China","institution_ids":["https://openalex.org/I196699116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114012760","display_name":"Quan Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I196699116","display_name":"Wuhan University of Technology","ror":"https://ror.org/03fe7t173","country_code":"CN","type":"education","lineage":["https://openalex.org/I196699116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Quan Liu","raw_affiliation_strings":["Wuhan University of Technology, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"Wuhan University of Technology, Wuhan, China","institution_ids":["https://openalex.org/I196699116"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079499220","display_name":"Andrew E. Hudson","orcid":"https://orcid.org/0000-0001-7292-5406"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew E. Hudson","raw_affiliation_strings":["University of California at Los Angeles, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"University of California at Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5064498583"],"corresponding_institution_ids":["https://openalex.org/I196699116"],"apc_list":null,"apc_paid":null,"fwci":0.5001,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.52792793,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2021","issue":null,"first_page":"117","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.7527238130569458},{"id":"https://openalex.org/keywords/electrocorticography","display_name":"Electrocorticography","score":0.7488804459571838},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5858535766601562},{"id":"https://openalex.org/keywords/wakefulness","display_name":"Wakefulness","score":0.5320181846618652},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.4938674569129944},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.46228718757629395},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.4601270854473114},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.4362891912460327},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"Prefrontal cortex","score":0.421994686126709},{"id":"https://openalex.org/keywords/power-graph-analysis","display_name":"Power graph analysis","score":0.41016483306884766},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3965710401535034},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.29352867603302},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.16826686263084412},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.14749690890312195},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.08193489909172058},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.07556679844856262}],"concepts":[{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.7527238130569458},{"id":"https://openalex.org/C2780117969","wikidata":"https://www.wikidata.org/wiki/Q3587624","display_name":"Electrocorticography","level":3,"score":0.7488804459571838},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5858535766601562},{"id":"https://openalex.org/C2779320081","wikidata":"https://www.wikidata.org/wiki/Q246710","display_name":"Wakefulness","level":3,"score":0.5320181846618652},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.4938674569129944},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.46228718757629395},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.4601270854473114},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4362891912460327},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.421994686126709},{"id":"https://openalex.org/C106937863","wikidata":"https://www.wikidata.org/wiki/Q7236518","display_name":"Power graph analysis","level":3,"score":0.41016483306884766},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3965710401535034},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.29352867603302},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.16826686263084412},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.14749690890312195},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.08193489909172058},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.07556679844856262},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069280","descriptor_name":"Electrocorticography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069280","descriptor_name":"Electrocorticography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069280","descriptor_name":"Electrocorticography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000882","descriptor_name":"Haplorhini","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000882","descriptor_name":"Haplorhini","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000882","descriptor_name":"Haplorhini","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014851","descriptor_name":"Wakefulness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014851","descriptor_name":"Wakefulness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014851","descriptor_name":"Wakefulness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc46164.2021.9631095","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9631095","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:34891252","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34891252","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1985673618","https://openalex.org/W1985741088","https://openalex.org/W2020300751","https://openalex.org/W2066823260","https://openalex.org/W2080966898","https://openalex.org/W2092598292","https://openalex.org/W2112482557","https://openalex.org/W2150967988","https://openalex.org/W2155367101","https://openalex.org/W2167822639","https://openalex.org/W2277019871","https://openalex.org/W2807263932","https://openalex.org/W2883197457","https://openalex.org/W2917658336","https://openalex.org/W2925881161","https://openalex.org/W3034435651","https://openalex.org/W6779098158"],"related_works":["https://openalex.org/W2587885761","https://openalex.org/W244352524","https://openalex.org/W2058775865","https://openalex.org/W3083677246","https://openalex.org/W2089088405","https://openalex.org/W2087148999","https://openalex.org/W4200524581","https://openalex.org/W2606402755","https://openalex.org/W2527813509","https://openalex.org/W4200418018"],"abstract_inverted_index":{"Increasingly,":[0],"studies":[1],"have":[2],"shown":[3],"that":[4,15,128],"changes":[5,59],"in":[6,25,53,60,84,92,107,149],"brain":[7,61,146],"network":[8,22,62,147],"topology":[9,109,148],"accompany":[10],"loss":[11],"of":[12,19,37,110,133,161],"consciousness":[13],"such":[14],"the":[16,20,70,77,100,108,111,145],"functional":[17,48,115,129],"connectivity":[18,49,98,116,130],"prefrontal-parietal":[21],"differs":[23],"significantly":[24],"anesthetized":[26,33,73,101,140,152],"and":[27,34,72,86,90,95,151,154],"awake":[28,35,71,78,138,150],"states.":[29,74],"In":[30],"this":[31],"work,":[32],"segments":[36],"electrocorticography":[38],"were":[39,51,81],"selected":[40],"from":[41],"two":[42],"monkeys.":[43],"Using":[44,114],"phase":[45],"lag":[46],"index,":[47],"matrices":[50],"built":[52],"multiple":[54],"frequency":[55],"bands.":[56],"Quantifying":[57],"topological":[58],"through":[63],"graph-theoretic":[64],"properties":[65],"revealed":[66],"significant":[67],"differences":[68],"between":[69],"Compared":[75],"to":[76,136],"state,":[79,102],"there":[80],"distinct":[82],"increases":[83],"overall":[85],"Delta":[87],"prefrontal-frontal":[88,97],"connectivity,":[89],"decreases":[91],"Alpha,":[93],"Beta1":[94],"Beta2":[96],"during":[99],"which":[103],"indicate":[104],"a":[105,120],"change":[106],"small-world":[112],"network.":[113],"features":[117,131],"we":[118],"achieved":[119],"satisfactory":[121],"classification":[122],"accuracy":[123],"(93.68%).":[124],"Our":[125],"study":[126],"demonstrates":[127],"are":[132],"sufficient":[134],"power":[135],"distinguish":[137],"versus":[139],"state.Clinical":[141],"Relevance-":[142],"This":[143],"explores":[144],"states,":[153],"provides":[155],"new":[156],"ideas":[157],"for":[158],"clinical":[159],"depth":[160],"anesthesia":[162],"monitoring.":[163]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}