{"id":"https://openalex.org/W4200431118","doi":"https://doi.org/10.1109/embc46164.2021.9630071","title":"A computational study of the relation between the power density in the tumor and the maximum temperature in the scalp during Tumor Treating Fields (TTFields) therapy","display_name":"A computational study of the relation between the power density in the tumor and the maximum temperature in the scalp during Tumor Treating Fields (TTFields) therapy","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200431118","doi":"https://doi.org/10.1109/embc46164.2021.9630071","pmid":"https://pubmed.ncbi.nlm.nih.gov/34892148"},"language":"en","primary_location":{"id":"doi:10.1109/embc46164.2021.9630071","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9630071","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Nichal Gentilal","orcid":null},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Nichal Gentilal","raw_affiliation_strings":["Instituto de Biof\u00edsica e Engenharia Biom\u00e9dica (IBEB), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, Lisboa, Portugal"],"affiliations":[{"raw_affiliation_string":"Instituto de Biof\u00edsica e Engenharia Biom\u00e9dica (IBEB), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, Lisboa, Portugal","institution_ids":["https://openalex.org/I141596103"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ariel Naveh","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ariel Naveh","raw_affiliation_strings":["Novocure, Haifa, Israel"],"affiliations":[{"raw_affiliation_string":"Novocure, Haifa, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tal Marciano","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tal Marciano","raw_affiliation_strings":["Novocure, Haifa, Israel"],"affiliations":[{"raw_affiliation_string":"Novocure, Haifa, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zeev Bomzon","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zeev Bomzon","raw_affiliation_strings":["Novocure, Haifa, Israel"],"affiliations":[{"raw_affiliation_string":"Novocure, Haifa, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yevgeniy Telepinsky","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yevgeniy Telepinsky","raw_affiliation_strings":["Novocure, Haifa, Israel"],"affiliations":[{"raw_affiliation_string":"Novocure, Haifa, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yoram Wasserman","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yoram Wasserman","raw_affiliation_strings":["Novocure, Haifa, Israel"],"affiliations":[{"raw_affiliation_string":"Novocure, Haifa, Israel","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Pedro Cavaleiro Miranda","orcid":null},"institutions":[{"id":"https://openalex.org/I141596103","display_name":"University of Lisbon","ror":"https://ror.org/01c27hj86","country_code":"PT","type":"education","lineage":["https://openalex.org/I141596103"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Pedro Cavaleiro Miranda","raw_affiliation_strings":["Instituto de Biof\u00edsica e Engenharia Biom\u00e9dica (IBEB), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, Lisboa, Portugal"],"affiliations":[{"raw_affiliation_string":"Instituto de Biof\u00edsica e Engenharia Biom\u00e9dica (IBEB), Faculdade de Ci\u00eancias, Universidade de Lisboa, Campo Grande, Lisboa, Portugal","institution_ids":["https://openalex.org/I141596103"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I141596103"],"apc_list":null,"apc_paid":null,"fwci":2.5231,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.90149626,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2021","issue":null,"first_page":"4192","last_page":"4195"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11565","display_name":"Thermoelastic and Magnetoelastic Phenomena","score":0.4352000057697296,"subfield":{"id":"https://openalex.org/subfields/2211","display_name":"Mechanics of Materials"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11565","display_name":"Thermoelastic and Magnetoelastic Phenomena","score":0.4352000057697296,"subfield":{"id":"https://openalex.org/subfields/2211","display_name":"Mechanics of Materials"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.21969999372959137,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.08879999816417694,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiphysics","display_name":"Multiphysics","score":0.7402999997138977},{"id":"https://openalex.org/keywords/scalp","display_name":"Scalp","score":0.7005000114440918},{"id":"https://openalex.org/keywords/work","display_name":"Work (physics)","score":0.5763000249862671},{"id":"https://openalex.org/keywords/power-density","display_name":"Power density","score":0.4894999861717224},{"id":"https://openalex.org/keywords/power","display_name":"Power (physics)","score":0.486299991607666},{"id":"https://openalex.org/keywords/point","display_name":"Point (geometry)","score":0.47029998898506165},{"id":"https://openalex.org/keywords/relation","display_name":"Relation (database)","score":0.42149999737739563}],"concepts":[{"id":"https://openalex.org/C46435376","wikidata":"https://www.wikidata.org/wiki/Q1829750","display_name":"Multiphysics","level":3,"score":0.7402999997138977},{"id":"https://openalex.org/C2778515351","wikidata":"https://www.wikidata.org/wiki/Q9622","display_name":"Scalp","level":2,"score":0.7005000114440918},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.5763000249862671},{"id":"https://openalex.org/C21881925","wikidata":"https://www.wikidata.org/wiki/Q3503313","display_name":"Power density","level":3,"score":0.4894999861717224},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.486299991607666},{"id":"https://openalex.org/C28719098","wikidata":"https://www.wikidata.org/wiki/Q44946","display_name":"Point (geometry)","level":2,"score":0.47029998898506165},{"id":"https://openalex.org/C25343380","wikidata":"https://www.wikidata.org/wiki/Q277521","display_name":"Relation (database)","level":2,"score":0.42149999737739563},{"id":"https://openalex.org/C2780312720","wikidata":"https://www.wikidata.org/wiki/Q5689100","display_name":"Head (geology)","level":2,"score":0.4214000105857849},{"id":"https://openalex.org/C2985831756","wikidata":"https://www.wikidata.org/wiki/Q107291880","display_name":"Maximum temperature","level":2,"score":0.4138000011444092},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.39010000228881836},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.373199999332428},{"id":"https://openalex.org/C204530211","wikidata":"https://www.wikidata.org/wiki/Q752823","display_name":"Thermal","level":2,"score":0.3653999865055084},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3407000005245209},{"id":"https://openalex.org/C207740977","wikidata":"https://www.wikidata.org/wiki/Q234072","display_name":"Current density","level":2,"score":0.33869999647140503},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.33660000562667847},{"id":"https://openalex.org/C2780549717","wikidata":"https://www.wikidata.org/wiki/Q3409626","display_name":"Human head","level":3,"score":0.3294000029563904},{"id":"https://openalex.org/C2985627981","wikidata":"https://www.wikidata.org/wiki/Q828827","display_name":"Power loss","level":3,"score":0.3084000051021576},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2867000102996826},{"id":"https://openalex.org/C197055811","wikidata":"https://www.wikidata.org/wiki/Q207522","display_name":"Probability density function","level":2,"score":0.2757999897003174},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.274399995803833},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2678999900817871},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.2526000142097473}],"mesh":[{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004599","descriptor_name":"Electric Stimulation Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004599","descriptor_name":"Electric Stimulation Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004599","descriptor_name":"Electric Stimulation Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012535","descriptor_name":"Scalp","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012535","descriptor_name":"Scalp","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012535","descriptor_name":"Scalp","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc46164.2021.9630071","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9630071","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:34892148","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34892148","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W2158030208","https://openalex.org/W2259397836","https://openalex.org/W2778283729","https://openalex.org/W2942152468","https://openalex.org/W2988303405","https://openalex.org/W3048619774"],"related_works":[],"abstract_inverted_index":{"In":[0],"this":[1],"work":[2],"we":[3,41],"investigated":[4],"the":[5,8,12,15,20,35,47],"relation":[6,59],"between":[7,60],"power":[9],"density":[10],"in":[11,19,37],"tumor":[13],"and":[14,40,64],"maximum":[16],"temperature":[17,48],"reached":[18],"scalp":[21],"during":[22],"TTFields":[23,66],"treatment":[24],"for":[25],"glioblastoma.":[26],"We":[27],"used":[28],"a":[29,57,70],"realistic":[30],"head":[31],"model":[32],"to":[33,45],"perform":[34],"simulations":[36],"COMSOL":[38],"Multiphysics":[39],"solved":[42],"Pennes'":[43],"equation":[44],"obtain":[46],"distribution.":[49],"Our":[50],"results":[51],"indicate":[52],"that":[53,65],"there":[54],"might":[55],"be":[56],"linear":[58],"these":[61],"two":[62],"quantities":[63],"are":[67],"safe":[68],"from":[69],"thermal":[71],"point":[72],"of":[73],"view.":[74]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-03-07T16:01:11.037858","created_date":"2021-12-31T00:00:00"}