{"id":"https://openalex.org/W4200159284","doi":"https://doi.org/10.1109/embc46164.2021.9629911","title":"Directed Network Mapping Approach to Rotor Localization in Atrial Fibrillation Simulation","display_name":"Directed Network Mapping Approach to Rotor Localization in Atrial Fibrillation Simulation","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200159284","doi":"https://doi.org/10.1109/embc46164.2021.9629911","pmid":"https://pubmed.ncbi.nlm.nih.gov/34891395"},"language":"en","primary_location":{"id":"doi:10.1109/embc46164.2021.9629911","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9629911","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2434/906828","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039207332","display_name":"Muhamed Vila","orcid":"https://orcid.org/0000-0002-9217-7502"},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Muhamed Vila","raw_affiliation_strings":["Department of Computer Science, Universit\u00e0 degli Studi di Milano, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Universit\u00e0 degli Studi di Milano, Milano, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024403759","display_name":"Sara Rocher","orcid":null},"institutions":[{"id":"https://openalex.org/I60053951","display_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","ror":"https://ror.org/01460j859","country_code":"ES","type":"education","lineage":["https://openalex.org/I60053951"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Sara Rocher","raw_affiliation_strings":["Centro de Investigati\u00f3n e Innovati\u00f3n en Bioingenier\u00eda, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Investigati\u00f3n e Innovati\u00f3n en Bioingenier\u00eda, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain","institution_ids":["https://openalex.org/I60053951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054009456","display_name":"Massimo W. Rivolta","orcid":"https://orcid.org/0000-0002-8553-2414"},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo W Rivolta","raw_affiliation_strings":["Department of Computer Science, Universit\u00e0 degli Studi di Milano, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Universit\u00e0 degli Studi di Milano, Milano, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063676325","display_name":"Javier S\u00e1iz","orcid":"https://orcid.org/0000-0002-9850-0825"},"institutions":[{"id":"https://openalex.org/I60053951","display_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","ror":"https://ror.org/01460j859","country_code":"ES","type":"education","lineage":["https://openalex.org/I60053951"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier Saiz","raw_affiliation_strings":["Centro de Investigati\u00f3n e Innovati\u00f3n en Bioingenier\u00eda, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Investigati\u00f3n e Innovati\u00f3n en Bioingenier\u00eda, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain","institution_ids":["https://openalex.org/I60053951"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039803457","display_name":"Roberto Sassi","orcid":"https://orcid.org/0000-0001-9729-2641"},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Sassi","raw_affiliation_strings":["Department of Computer Science, Universit\u00e0 degli Studi di Milano, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Universit\u00e0 degli Studi di Milano, Milano, Italy","institution_ids":["https://openalex.org/I189158943"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.344,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.39497307,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"37","issue":null,"first_page":"730","last_page":"733"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ablation","display_name":"Ablation","score":0.7530825734138489},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"Atrial fibrillation","score":0.6394757628440857},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5876551866531372},{"id":"https://openalex.org/keywords/catheter-ablation","display_name":"Catheter ablation","score":0.5510674715042114},{"id":"https://openalex.org/keywords/vertex","display_name":"Vertex (graph theory)","score":0.5404765009880066},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.31843072175979614},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3096914291381836},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.20395886898040771},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.14805644750595093}],"concepts":[{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.7530825734138489},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.6394757628440857},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5876551866531372},{"id":"https://openalex.org/C2776131983","wikidata":"https://www.wikidata.org/wiki/Q436572","display_name":"Catheter ablation","level":3,"score":0.5510674715042114},{"id":"https://openalex.org/C80899671","wikidata":"https://www.wikidata.org/wiki/Q1304193","display_name":"Vertex (graph theory)","level":3,"score":0.5404765009880066},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.31843072175979614},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3096914291381836},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20395886898040771},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.14805644750595093}],"mesh":[{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006325","descriptor_name":"Heart Atria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006325","descriptor_name":"Heart Atria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006325","descriptor_name":"Heart Atria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017115","descriptor_name":"Catheter Ablation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017115","descriptor_name":"Catheter Ablation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017115","descriptor_name":"Catheter Ablation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D022062","descriptor_name":"Electrophysiologic Techniques, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022062","descriptor_name":"Electrophysiologic Techniques, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022062","descriptor_name":"Electrophysiologic Techniques, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc46164.2021.9629911","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9629911","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:34891395","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34891395","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:air.unimi.it:2434/906828","is_oa":true,"landing_page_url":"http://hdl.handle.net/2434/906828","pdf_url":null,"source":{"id":"https://openalex.org/S4306400516","display_name":"Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I189158943","host_organization_name":"University of Milan","host_organization_lineage":["https://openalex.org/I189158943"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bookPart"}],"best_oa_location":{"id":"pmh:oai:air.unimi.it:2434/906828","is_oa":true,"landing_page_url":"http://hdl.handle.net/2434/906828","pdf_url":null,"source":{"id":"https://openalex.org/S4306400516","display_name":"Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I189158943","host_organization_name":"University of Milan","host_organization_lineage":["https://openalex.org/I189158943"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bookPart"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7015312239","display_name":"MultidisciplinarY training network for ATrial fibRillation monItoring, treAtment and progression","funder_award_id":"766082","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7842005466","display_name":null,"funder_award_id":"Horizon 2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W25713472","https://openalex.org/W1928634140","https://openalex.org/W2034870521","https://openalex.org/W2053274299","https://openalex.org/W2060299481","https://openalex.org/W2092325702","https://openalex.org/W2104749146","https://openalex.org/W2122843638","https://openalex.org/W2129656446","https://openalex.org/W2166966593","https://openalex.org/W2498084015","https://openalex.org/W2555941270","https://openalex.org/W2793507168","https://openalex.org/W2969527505","https://openalex.org/W3004050106"],"related_works":["https://openalex.org/W2126958622","https://openalex.org/W2405738564","https://openalex.org/W2997443537","https://openalex.org/W4210927327","https://openalex.org/W63965692","https://openalex.org/W4392301378","https://openalex.org/W3151790662","https://openalex.org/W4392365030","https://openalex.org/W4292689102","https://openalex.org/W2179224909"],"abstract_inverted_index":{"Catheter":[0],"ablation":[1,28,47,64,99],"for":[2,32,58,96,234],"atrial":[3,206,258],"fibrillation":[4],"(AF)":[5],"is":[6,45,73,154,210],"one":[7],"of":[8,21,62,70,88,119,127,167,175,194,199,236,276,281],"the":[9,25,85,98,112,116,120,125,128,176,185,200,205,243,252,269],"most":[10],"commonly":[11],"performed":[12],"electrophysiology":[13],"procedures.":[14],"Despite":[15],"significant":[16],"advances":[17],"in":[18,24,170,204,214,246,273,285],"our":[19],"understanding":[20],"AF":[22,209],"mechanisms":[23],"last":[26],"years,":[27],"outcomes":[29],"remain":[30],"suboptimal":[31],"many":[33],"patients,":[34],"particularly":[35],"those":[36],"with":[37],"persistent":[38],"or":[39],"long-standing":[40],"AF.":[41],"A":[42],"possible":[43],"reason":[44],"that":[46,92],"techniques":[48],"mainly":[49],"focus":[50],"on":[51,80,184],"anatomic,":[52],"rather":[53],"than":[54],"patient-specific":[55],"functional":[56],"targets":[57,65],"ablation.":[59],"The":[60,68,101,139,197,256],"identification":[61],"such":[63],"remains":[66],"challenging.":[67],"purpose":[69],"this":[71],"study":[72,157],"to":[74,147,216,251],"investigate":[75],"a":[76,150,155,161,231,266,289],"novel":[77],"approach":[78],"based":[79],"directed":[81],"networks,":[82,278],"which":[83,171],"allow":[84],"automatic":[86],"detection":[87],"important":[89],"arrhythmia":[90],"mechanisms,":[91],"can":[93],"be":[94],"convenient":[95],"guiding":[97],"strategy.":[100],"networks":[102,248,283],"are":[103,132],"generated":[104],"by":[105,111],"processing":[106],"unipolar":[107],"electrograms":[108],"(EGMs)":[109],"collected":[110],"catheters":[113],"positioned":[114],"at":[115,192],"different":[117],"regions":[118],"atria.":[121],"Network":[122],"vertices":[123],"represent":[124],"locations":[126],"recordings":[129],"and":[130,158,188,242],"edges":[131],"determined":[133],"using":[134],"cross-covariance":[135],"time-delay":[136],"estimation":[137],"method.":[138],"algorithm":[140],"identifies":[141],"rotational":[142],"activity,":[143],"spreading":[144],"from":[145],"vertex":[146,148],"creating":[149],"cycle.":[151],"This":[152],"work":[153],"simulation":[156],"it":[159],"uses":[160],"highly":[162],"detailed":[163],"computational":[164],"3D":[165],"model":[166],"human":[168],"atria":[169,177],"sustained":[172],"rotor":[173,291],"activation":[174],"was":[178,240,292],"achieved.":[179],"Virtual":[180],"electrodes":[181],"were":[182,190,284],"placed":[183],"endocardial":[186],"surface,":[187],"EGMs":[189,224],"calculated":[191],"each":[193,235],"these":[195,237,282],"electrodes.":[196],"propagation":[198,220],"electric":[201],"wave":[202,219],"fronts":[203],"myocardium":[207],"during":[208],"very":[211],"complex,":[212],"so":[213],"order":[215],"properly":[217],"capture":[218],"patterns,":[221],"we":[222],"split":[223],"into":[225],"multiple":[226],"short":[227],"time":[228,238,287],"frames.":[229],"Then,":[230],"specific":[232],"network":[233],"frames":[239],"generated,":[241],"cycles":[244],"repeating":[245],"consecutive":[247,286],"point":[249],"us":[250],"stable":[253,290],"rotor's":[254],"location.":[255],"respective":[257],"voltage":[259],"map":[260],"served":[261],"as":[262],"reference.":[263],"By":[264],"detecting":[265],"cycle":[267],"between":[268],"same":[270],"3":[271],"nodes":[272],"19":[274],"out":[275],"58":[277],"where":[279],"10":[280],"frames,":[288],"successfully":[293],"located.":[294]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-06-16T09:24:06.705377","created_date":"2025-10-10T00:00:00"}