{"id":"https://openalex.org/W4200182489","doi":"https://doi.org/10.1109/embc46164.2021.9629832","title":"Design of Experiment Evaluation of a 2.5D Printing Process for Implantable PDMS-based Neural Interfaces","display_name":"Design of Experiment Evaluation of a 2.5D Printing Process for Implantable PDMS-based Neural Interfaces","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200182489","doi":"https://doi.org/10.1109/embc46164.2021.9629832","pmid":"https://pubmed.ncbi.nlm.nih.gov/34892584"},"language":"en","primary_location":{"id":"doi:10.1109/embc46164.2021.9629832","is_oa":true,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9629832","pdf_url":"https://ieeexplore.ieee.org/ielx7/9629355/9629471/09629832.pdf","source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ieeexplore.ieee.org/ielx7/9629355/9629471/09629832.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Y. Baslan","orcid":null},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Y. Baslan","raw_affiliation_strings":["Laboratory of Biomedical Microtechnology, University of Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomedical Microtechnology, University of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. Stieglitz","orcid":null},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210098324","display_name":"Bernstein Center for Computational Neuroscience Freiburg","ror":"https://ror.org/010p50m34","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210092532","https://openalex.org/I4210098324"]},{"id":"https://openalex.org/I4210113520","display_name":"Brain (Germany)","ror":"https://ror.org/01gamcy45","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210113520"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"T. Stieglitz","raw_affiliation_strings":["Bernstein Center Freiburg and BrainLinks-BrainTools, University of Freiburg"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bernstein Center Freiburg and BrainLinks-BrainTools, University of Freiburg","institution_ids":["https://openalex.org/I4210098324","https://openalex.org/I161046081","https://openalex.org/I4210113520"]}]},{"author_position":"last","author":{"id":null,"display_name":"P. Kiele","orcid":null},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P. Kiele","raw_affiliation_strings":["Laboratory of Biomedical Microtechnology, University of Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Biomedical Microtechnology, University of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4941,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.49193548,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2021","issue":null,"first_page":"6433","last_page":"6436"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.866100013256073,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.866100013256073,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.04699999839067459,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fabrication","display_name":"Fabrication","score":0.7159000039100647},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.5759999752044678},{"id":"https://openalex.org/keywords/electrical-conductor","display_name":"Electrical conductor","score":0.5174000263214111},{"id":"https://openalex.org/keywords/3d-printing","display_name":"3D printing","score":0.4198000133037567},{"id":"https://openalex.org/keywords/screen-printing","display_name":"Screen printing","score":0.3716999888420105},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.3587000072002411},{"id":"https://openalex.org/keywords/inkwell","display_name":"Inkwell","score":0.3560999929904938}],"concepts":[{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.7159000039100647},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5759999752044678},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5253000259399414},{"id":"https://openalex.org/C202374169","wikidata":"https://www.wikidata.org/wiki/Q124291","display_name":"Electrical conductor","level":2,"score":0.5174000263214111},{"id":"https://openalex.org/C524769229","wikidata":"https://www.wikidata.org/wiki/Q229367","display_name":"3D printing","level":2,"score":0.4198000133037567},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38609999418258667},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.37959998846054077},{"id":"https://openalex.org/C2776422346","wikidata":"https://www.wikidata.org/wiki/Q187791","display_name":"Screen printing","level":2,"score":0.3716999888420105},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.3587000072002411},{"id":"https://openalex.org/C109693293","wikidata":"https://www.wikidata.org/wiki/Q1496072","display_name":"Inkwell","level":2,"score":0.3560999929904938},{"id":"https://openalex.org/C34559072","wikidata":"https://www.wikidata.org/wiki/Q2334061","display_name":"Design of experiments","level":2,"score":0.35429999232292175},{"id":"https://openalex.org/C2780395129","wikidata":"https://www.wikidata.org/wiki/Q1128971","display_name":"Rapid prototyping","level":2,"score":0.3529999852180481},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.3334999978542328},{"id":"https://openalex.org/C30239060","wikidata":"https://www.wikidata.org/wiki/Q5253111","display_name":"Delamination (geology)","level":4,"score":0.33180001378059387},{"id":"https://openalex.org/C2987875673","wikidata":"https://www.wikidata.org/wiki/Q187939","display_name":"Manufacturing process","level":2,"score":0.3287000060081482},{"id":"https://openalex.org/C199639397","wikidata":"https://www.wikidata.org/wiki/Q1788588","display_name":"Engineering drawing","level":1,"score":0.2992999851703644},{"id":"https://openalex.org/C2779015675","wikidata":"https://www.wikidata.org/wiki/Q92796261","display_name":"Breakage","level":2,"score":0.2989000082015991},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.25949999690055847},{"id":"https://openalex.org/C97562148","wikidata":"https://www.wikidata.org/wiki/Q5357989","display_name":"Electrode array","level":3,"score":0.2531000077724457}],"mesh":[{"descriptor_ui":"D004553","descriptor_name":"Electric Conductivity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004553","descriptor_name":"Electric Conductivity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004553","descriptor_name":"Electric Conductivity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D066330","descriptor_name":"Printing, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc46164.2021.9629832","is_oa":true,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9629832","pdf_url":"https://ieeexplore.ieee.org/ielx7/9629355/9629471/09629832.pdf","source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:34892584","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34892584","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":{"id":"doi:10.1109/embc46164.2021.9629832","is_oa":true,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9629832","pdf_url":"https://ieeexplore.ieee.org/ielx7/9629355/9629471/09629832.pdf","source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3992011476","display_name":null,"funder_award_id":"16SV7656","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"}],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320321408","display_name":"Ministry of Education","ror":"https://ror.org/01p262204"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4200182489.pdf","grobid_xml":"https://content.openalex.org/works/W4200182489.grobid-xml"},"referenced_works_count":3,"referenced_works":["https://openalex.org/W319220122","https://openalex.org/W1963876699","https://openalex.org/W2317302777"],"related_works":[],"abstract_inverted_index":{"Current":[0],"laser":[1],"fabrication":[2,113],"processes":[3,129],"for":[4,62,97,105,133],"PDMS-based":[5],"neural":[6,118,135],"interfaces":[7,136],"are":[8,31],"associated":[9],"with":[10,91],"excessive":[11],"costs,":[12],"due":[13],"to":[14,33,137],"time-consuming":[15],"manual":[16],"handling":[17],"and":[18,107,116],"expensive":[19],"machinery.":[20],"The":[21,65,82],"products":[22],"of":[23,79,85,94,114,142],"this":[24,48],"process,":[25,56],"specifically":[26],"embedded":[27],"metallic":[28],"electrical":[29],"tracks,":[30],"prone":[32],"breakage":[34],"under":[35],"mechanical":[36],"loading,":[37],"as":[38,40],"well":[39],"delamination":[41],"from":[42],"their":[43],"surrounding":[44],"PDMS":[45,60,109],"substrates.":[46],"In":[47],"work,":[49],"we":[50],"develop":[51],"an":[52],"alternative":[53],"2.5D":[54,127],"printing":[55,73,83,103,128],"using":[57],"electrically":[58],"conductive":[59,106],"material":[61],"the":[63,77,86,92,112,123,131,139],"tracks.":[64],"entire":[66],"electrode":[67],"was":[68,89],"fabricated":[69],"in":[70],"a":[71],"custom-made":[72],"setup,":[74],"which":[75,110],"features":[76],"possibility":[78],"rapid":[80],"prototyping.":[81],"performance":[84],"selected":[87],"materials":[88],"evaluated":[90],"aid":[93],"statistical":[95],"methods":[96],"experimental":[98],"design.":[99],"We":[100],"found":[101],"optimal":[102],"parameters":[104],"non-conductive":[108],"allows":[111],"flexible":[115],"stretchable":[117],"interfaces,":[119],"while":[120],"simultaneously":[121],"minimizing":[122],"track":[124],"resistivity.Clinical":[125],"Relevance-":[126],"pave":[130],"way":[132],"individualized":[134],"suit":[138],"specific":[140],"needs":[141],"every":[143],"single":[144],"patient.":[145]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2021-12-31T00:00:00"}