{"id":"https://openalex.org/W3195075825","doi":"https://doi.org/10.1109/embc46164.2021.9629698","title":"Multi-Slice Dense-Sparse Learning for Efficient Liver and Tumor Segmentation","display_name":"Multi-Slice Dense-Sparse Learning for Efficient Liver and Tumor Segmentation","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W3195075825","doi":"https://doi.org/10.1109/embc46164.2021.9629698","mag":"3195075825","pmid":"https://pubmed.ncbi.nlm.nih.gov/34892013"},"language":"en","primary_location":{"id":"doi:10.1109/embc46164.2021.9629698","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9629698","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine &amp; Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine &amp; Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["arxiv","crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2108.06761","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050743199","display_name":"Ziyuan Zhao","orcid":"https://orcid.org/0000-0002-4403-825X"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Ziyuan Zhao","raw_affiliation_strings":["Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I3005327000"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030001981","display_name":"Zeyu Ma","orcid":"https://orcid.org/0000-0002-2553-0679"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Zeyu Ma","raw_affiliation_strings":["Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore","National University of Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I3005327000"]},{"raw_affiliation_string":"National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100601303","display_name":"Yanjie Liu","orcid":"https://orcid.org/0000-0002-7274-4979"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yanjie Liu","raw_affiliation_strings":["Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore","National University of Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I3005327000"]},{"raw_affiliation_string":"National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010092389","display_name":"Zeng Zeng","orcid":"https://orcid.org/0000-0002-2405-0323"},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I3005327000","display_name":"Institute for Infocomm Research","ror":"https://ror.org/053rfa017","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I3005327000","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Zeng Zeng","raw_affiliation_strings":["Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Infocomm Research (I2R), Agency for Science, Technology and Research, A*STAR, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I3005327000"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061027234","display_name":"Pierce K. H. Chow","orcid":"https://orcid.org/0000-0003-0584-2584"},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]},{"id":"https://openalex.org/I4210126319","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I170897317","https://openalex.org/I4210126319"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Pierce KH Chow","raw_affiliation_strings":["Dept of Hepatopancreatobiliary Surgery and Transplant, National Cancer Center, Singapore General Hospital, Singapore","Duke-NUS Medical School Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Hepatopancreatobiliary Surgery and Transplant, National Cancer Center, Singapore General Hospital, Singapore","institution_ids":["https://openalex.org/I2251586001"]},{"raw_affiliation_string":"Duke-NUS Medical School Singapore","institution_ids":["https://openalex.org/I4210126319"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5729,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.75922082,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"2021","issue":null,"first_page":"3582","last_page":"3585"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11775","display_name":"COVID-19 diagnosis using AI","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7993462681770325},{"id":"https://openalex.org/keywords/leverage","display_name":"Leverage (statistics)","score":0.7568714022636414},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6987214684486389},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.650895357131958},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6488029956817627},{"id":"https://openalex.org/keywords/perspective","display_name":"Perspective (graphical)","score":0.5571961998939514},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.539131760597229},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.43316900730133057},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.41207608580589294}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7993462681770325},{"id":"https://openalex.org/C153083717","wikidata":"https://www.wikidata.org/wiki/Q6535263","display_name":"Leverage (statistics)","level":2,"score":0.7568714022636414},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6987214684486389},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.650895357131958},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6488029956817627},{"id":"https://openalex.org/C12713177","wikidata":"https://www.wikidata.org/wiki/Q1900281","display_name":"Perspective (graphical)","level":2,"score":0.5571961998939514},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.539131760597229},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.43316900730133057},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.41207608580589294}],"mesh":[{"descriptor_ui":"D000005","descriptor_name":"Abdomen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000005","descriptor_name":"Abdomen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000005","descriptor_name":"Abdomen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc46164.2021.9629698","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc46164.2021.9629698","pdf_url":null,"source":{"id":"https://openalex.org/S4363607750","display_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine &amp; Biology Society (EMBC)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 43rd Annual International Conference of the IEEE Engineering in Medicine &amp; Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:34892013","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34892013","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:arXiv.org:2108.06761","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2108.06761","pdf_url":"https://arxiv.org/pdf/2108.06761","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2108.06761","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2108.06761","pdf_url":"https://arxiv.org/pdf/2108.06761","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"score":0.6399999856948853,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1901129140","https://openalex.org/W2162657122","https://openalex.org/W2357815549","https://openalex.org/W2395611524","https://openalex.org/W2463818697","https://openalex.org/W2522861252","https://openalex.org/W2526009326","https://openalex.org/W2550380503","https://openalex.org/W2592929672","https://openalex.org/W2759532730","https://openalex.org/W2888011474","https://openalex.org/W2897666251","https://openalex.org/W2910094941","https://openalex.org/W2921406441","https://openalex.org/W2947263797","https://openalex.org/W2951123255","https://openalex.org/W2953643168","https://openalex.org/W2963789949","https://openalex.org/W2964227007","https://openalex.org/W2965669393","https://openalex.org/W2996201606","https://openalex.org/W3014974815","https://openalex.org/W3082835591","https://openalex.org/W3082921269","https://openalex.org/W3100369519","https://openalex.org/W3101123465","https://openalex.org/W3103010481","https://openalex.org/W3112701542","https://openalex.org/W4308909683","https://openalex.org/W4309233581","https://openalex.org/W6639824700","https://openalex.org/W6640054144","https://openalex.org/W6719642423"],"related_works":["https://openalex.org/W4293226380","https://openalex.org/W4226493464","https://openalex.org/W4312417841","https://openalex.org/W3193565141","https://openalex.org/W3133861977","https://openalex.org/W2951211570","https://openalex.org/W3103566983","https://openalex.org/W3167935049","https://openalex.org/W3029198973","https://openalex.org/W1522196789"],"abstract_inverted_index":{"Accurate":[0],"automatic":[1],"liver":[2],"and":[3,13,28,48,72,132],"tumor":[4],"segmentation":[5],"plays":[6],"a":[7,58,64,91,96],"vital":[8],"role":[9],"in":[10,26,67,99],"treatment":[11],"planning":[12],"disease":[14],"monitoring.":[15],"Recently,":[16],"deep":[17],"convolutional":[18],"neural":[19],"network":[20,97],"(DCNNs)":[21],"has":[22],"obtained":[23],"tremendous":[24],"success":[25],"2D":[27,34],"3D":[29,43],"medical":[30],"image":[31],"segmentation.":[32],"However,":[33],"DCNNs":[35,44],"cannot":[36],"fully":[37],"leverage":[38],"the":[39,85,108,113,118,121],"inter-slice":[40],"information,":[41],"while":[42],"are":[45,76,104],"computationally":[46],"expensive":[47],"memory":[49],"intensive.":[50],"To":[51],"address":[52],"these":[53],"issues,":[54],"we":[55,89],"first":[56],"propose":[57],"novel":[59],"dense-sparse":[60],"training":[61],"flow":[62],"from":[63,95,134],"data":[65],"perspective,":[66,98],"which,":[68,100],"densely":[69],"adjacent":[70,74],"slices":[71,75],"sparsely":[73],"extracted":[77],"as":[78],"inputs":[79],"for":[80],"regularizing":[81],"DCNNs,":[82],"thereby":[83],"improving":[84],"model":[86],"performance.":[87],"Moreover,":[88],"design":[90],"2.5D":[92],"light-weight":[93],"nnU-Net":[94],"depthwise":[101],"separable":[102],"convolutions":[103],"adopted":[105],"to":[106],"improve":[107],"efficiency.":[109],"Extensive":[110],"experiments":[111],"on":[112],"LiTS":[114],"dataset":[115],"have":[116],"demonstrated":[117],"superiority":[119],"of":[120],"proposed":[122,126],"method.Clinical":[123],"relevance-":[124],"The":[125],"method":[127],"can":[128,141],"effectively":[129],"segment":[130],"livers":[131],"tumors":[133],"CT":[135],"scans":[136],"with":[137],"low":[138],"complexity,":[139],"which":[140],"be":[142],"easily":[143],"implemented":[144],"into":[145],"clinical":[146],"practice.":[147]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2}],"updated_date":"2026-08-05T07:39:15.569665","created_date":"2025-10-10T00:00:00"}
