{"id":"https://openalex.org/W3082575382","doi":"https://doi.org/10.1109/embc44109.2020.9175226","title":"Methodological Considerations on EEG Electrical Reference: A Functional Brain-Heart Interplay Study","display_name":"Methodological Considerations on EEG Electrical Reference: A Functional Brain-Heart Interplay Study","publication_year":2020,"publication_date":"2020-07-01","ids":{"openalex":"https://openalex.org/W3082575382","doi":"https://doi.org/10.1109/embc44109.2020.9175226","mag":"3082575382","pmid":"https://pubmed.ncbi.nlm.nih.gov/33018049"},"language":"en","primary_location":{"id":"doi:10.1109/embc44109.2020.9175226","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc44109.2020.9175226","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/11568/1066908","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089550332","display_name":"Diego Candia\u2010Rivera","orcid":"https://orcid.org/0000-0002-4043-217X"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I1300504238","display_name":"Piaggio (Italy)","ror":"https://ror.org/00r254y42","country_code":"IT","type":"company","lineage":["https://openalex.org/I1300504238"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Diego Candia-Rivera","raw_affiliation_strings":["Bioengineering and Robotics Research Center E. Piaggio and the Department of Information Engineering, University of Pisa, Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering and Robotics Research Center E. Piaggio and the Department of Information Engineering, University of Pisa, Pisa, Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013014934","display_name":"Vincenzo Catrambone","orcid":"https://orcid.org/0000-0001-9030-7601"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I1300504238","display_name":"Piaggio (Italy)","ror":"https://ror.org/00r254y42","country_code":"IT","type":"company","lineage":["https://openalex.org/I1300504238"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Vincenzo Catrambone","raw_affiliation_strings":["Bioengineering and Robotics Research Center E. Piaggio and the Department of Information Engineering, University of Pisa, Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering and Robotics Research Center E. Piaggio and the Department of Information Engineering, University of Pisa, Pisa, Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041459422","display_name":"Gaetano Valenza","orcid":"https://orcid.org/0000-0001-6574-1879"},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I1300504238","display_name":"Piaggio (Italy)","ror":"https://ror.org/00r254y42","country_code":"IT","type":"company","lineage":["https://openalex.org/I1300504238"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gaetano Valenza","raw_affiliation_strings":["Bioengineering and Robotics Research Center E. Piaggio and the Department of Information Engineering, University of Pisa, Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering and Robotics Research Center E. Piaggio and the Department of Information Engineering, University of Pisa, Pisa, Italy","institution_ids":["https://openalex.org/I1300504238","https://openalex.org/I108290504"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5469,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.62977037,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2020","issue":null,"first_page":"553","last_page":"556"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.8985124826431274},{"id":"https://openalex.org/keywords/heartbeat","display_name":"Heartbeat","score":0.8539752960205078},{"id":"https://openalex.org/keywords/preprocessor","display_name":"Preprocessor","score":0.48274677991867065},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4736810028553009},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.42132532596588135},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4209398627281189},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.29456421732902527},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1800146996974945}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.8985124826431274},{"id":"https://openalex.org/C13852961","wikidata":"https://www.wikidata.org/wiki/Q17021880","display_name":"Heartbeat","level":2,"score":0.8539752960205078},{"id":"https://openalex.org/C34736171","wikidata":"https://www.wikidata.org/wiki/Q918333","display_name":"Preprocessor","level":2,"score":0.48274677991867065},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4736810028553009},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.42132532596588135},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4209398627281189},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.29456421732902527},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1800146996974945},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004560","descriptor_name":"Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004560","descriptor_name":"Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004560","descriptor_name":"Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1109/embc44109.2020.9175226","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc44109.2020.9175226","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:33018049","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33018049","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:arpi.unipi.it:11568/1066908","is_oa":true,"landing_page_url":"https://hdl.handle.net/11568/1066908","pdf_url":null,"source":{"id":"https://openalex.org/S4377196265","display_name":"CINECA IRIS Institutial research information system (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:zenodo.org:4724439","is_oa":true,"landing_page_url":"https://zenodo.org/record/4724439","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferencePaper"}],"best_oa_location":{"id":"pmh:oai:arpi.unipi.it:11568/1066908","is_oa":true,"landing_page_url":"https://hdl.handle.net/11568/1066908","pdf_url":null,"source":{"id":"https://openalex.org/S4377196265","display_name":"CINECA IRIS Institutial research information system (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1969311702","https://openalex.org/W2007503766","https://openalex.org/W2011695541","https://openalex.org/W2011805513","https://openalex.org/W2023222401","https://openalex.org/W2052769522","https://openalex.org/W2056144146","https://openalex.org/W2079217989","https://openalex.org/W2085064542","https://openalex.org/W2085182169","https://openalex.org/W2100089210","https://openalex.org/W2115332350","https://openalex.org/W2136547127","https://openalex.org/W2142823391","https://openalex.org/W2149859795","https://openalex.org/W2155805591","https://openalex.org/W2158976222","https://openalex.org/W2165700458","https://openalex.org/W2166073443","https://openalex.org/W2327416138","https://openalex.org/W2771693746","https://openalex.org/W2792847701","https://openalex.org/W2803455040","https://openalex.org/W2940246131","https://openalex.org/W2942820605","https://openalex.org/W2948819849","https://openalex.org/W2981764557","https://openalex.org/W6763499241"],"related_works":["https://openalex.org/W4385543909","https://openalex.org/W3039320222","https://openalex.org/W3199640442","https://openalex.org/W1898280036","https://openalex.org/W2315807364","https://openalex.org/W2382278803","https://openalex.org/W2113096447","https://openalex.org/W2053322856","https://openalex.org/W2033914206","https://openalex.org/W2042327336"],"abstract_inverted_index":{"The":[0],"growing":[1],"interest":[2],"in":[3,67],"the":[4,13,35,74,94,129,140,151,157],"study":[5],"of":[6,15,25,37,159],"functional":[7,167],"brain-heart":[8],"interplay":[9],"(BHI)":[10],"has":[11,31],"motivated":[12],"development":[14],"novel":[16],"methodological":[17],"frameworks":[18],"for":[19],"its":[20],"quantification.":[21,169],"While":[22],"a":[23,41,120,166],"combination":[24],"electroencephalography":[26],"(EEG)":[27],"and":[28,83,101,104,114],"heartbeat-derived":[29],"series":[30],"been":[32],"widely":[33],"used,":[34],"role":[36],"EEG":[38,56,88,131,147,160],"preprocessing":[39],"on":[40,53,128],"BHI":[42,62,71,116,124,136,168],"quantification":[43],"is":[44],"yet":[45],"unknown.":[46],"To":[47],"this":[48],"extent,":[49],"here":[50],"we":[51],"investigate":[52],"four":[54],"different":[55],"electrical":[57,161],"referencing":[58],"techniques":[59],"associated":[60],"with":[61,139,150],"quantifications":[63],"over":[64],"4-minute":[65],"resting-state":[66],"15":[68],"healthy":[69],"subjects.":[70],"methods":[72,126,137],"include":[73],"synthetic":[75],"data":[76],"generation":[77],"model,":[78],"heartbeat-evoked":[79,81],"potentials,":[80],"oscillations,":[82],"maximal":[84],"information":[85],"coefficient":[86],"(MIC).":[87],"signals":[89],"were":[90,107],"offline":[91],"referenced":[92],"under":[93],"Cz":[95],"channel,":[96],"common":[97],"average,":[98,100],"mastoids":[99],"Laplacian":[102,141],"method,":[103],"statistical":[105],"comparisons":[106],"performed":[108],"to":[109],"assess":[110],"similarities":[111],"between":[112,115,123,135,146],"references":[113,148],"techniques.":[117],"Results":[118],"show":[119],"topographical":[121],"agreement":[122],"estimation":[125],"depending":[127],"specific":[130],"reference.":[132],"Major":[133],"differences":[134,145],"occur":[138],"reference,":[142],"while":[143],"major":[144],"are":[149],"MIC":[152],"analysis.":[153],"We":[154],"conclude":[155],"that":[156],"choice":[158],"reference":[162],"may":[163],"significantly":[164],"affect":[165]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":4}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}