{"id":"https://openalex.org/W4389542907","doi":"https://doi.org/10.1109/embc40787.2023.10340357","title":"Image-Based Tools and Analysis for Human RVOT/RV Structures*","display_name":"Image-Based Tools and Analysis for Human RVOT/RV Structures*","publication_year":2023,"publication_date":"2023-07-24","ids":{"openalex":"https://openalex.org/W4389542907","doi":"https://doi.org/10.1109/embc40787.2023.10340357","pmid":"https://pubmed.ncbi.nlm.nih.gov/38083720"},"language":"en","primary_location":{"id":"doi:10.1109/embc40787.2023.10340357","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/embc40787.2023.10340357","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073737510","display_name":"Mark L. Trew","orcid":"https://orcid.org/0000-0003-4296-8231"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Mark L. Trew","raw_affiliation_strings":["University of Auckland,Auckland Bioengineering Institute,New Zealand","Auckland Bioengineering Institute, University of Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"University of Auckland,Auckland Bioengineering Institute,New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059420697","display_name":"Gregory B. Sands","orcid":"https://orcid.org/0000-0002-7875-2099"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Gregory B. Sands","raw_affiliation_strings":["University of Auckland,Auckland Bioengineering Institute,New Zealand","Auckland Bioengineering Institute, University of Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"University of Auckland,Auckland Bioengineering Institute,New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009753955","display_name":"Zhiyong Yang","orcid":"https://orcid.org/0000-0002-4409-4999"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Zhiyong Yang","raw_affiliation_strings":["University of Auckland,Auckland Bioengineering Institute,New Zealand","Auckland Bioengineering Institute, University of Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"University of Auckland,Auckland Bioengineering Institute,New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034624572","display_name":"Jesse L. Ashton","orcid":"https://orcid.org/0000-0003-2376-652X"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Jesse L. Ashton","raw_affiliation_strings":["University of Auckland,Auckland Bioengineering Institute,New Zealand","Auckland Bioengineering Institute, University of Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"University of Auckland,Auckland Bioengineering Institute,New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046063734","display_name":"Vibujithan Vigneshwaran","orcid":"https://orcid.org/0000-0003-3377-5526"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Vibujithan Vigneshwaran","raw_affiliation_strings":["University of Auckland,Auckland Bioengineering Institute,New Zealand","Auckland Bioengineering Institute, University of Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"University of Auckland,Auckland Bioengineering Institute,New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071099770","display_name":"Richard D. Walton","orcid":"https://orcid.org/0000-0002-9687-2545"},"institutions":[{"id":"https://openalex.org/I15057530","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530"]},{"id":"https://openalex.org/I4210086115","display_name":"Electrophysiology and Heart Modeling Institute","ror":"https://ror.org/00jsv7j98","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I154526488","https://openalex.org/I3018323443","https://openalex.org/I4210086115"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Richard D. Walton","raw_affiliation_strings":["University of Bordeaux,IHU Liryc,France","IHU Liryc, University of Bordeaux, France"],"affiliations":[{"raw_affiliation_string":"University of Bordeaux,IHU Liryc,France","institution_ids":["https://openalex.org/I15057530","https://openalex.org/I4210086115"]},{"raw_affiliation_string":"IHU Liryc, University of Bordeaux, France","institution_ids":["https://openalex.org/I4210086115","https://openalex.org/I15057530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015636460","display_name":"Olivier Bernus","orcid":"https://orcid.org/0000-0003-3917-5791"},"institutions":[{"id":"https://openalex.org/I15057530","display_name":"Universit\u00e9 de Bordeaux","ror":"https://ror.org/057qpr032","country_code":"FR","type":"education","lineage":["https://openalex.org/I15057530"]},{"id":"https://openalex.org/I4210086115","display_name":"Electrophysiology and Heart Modeling Institute","ror":"https://ror.org/00jsv7j98","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1326498283","https://openalex.org/I154526488","https://openalex.org/I3018323443","https://openalex.org/I4210086115"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Oliver Bernus","raw_affiliation_strings":["University of Bordeaux,IHU Liryc,France","IHU Liryc, University of Bordeaux, France"],"affiliations":[{"raw_affiliation_string":"University of Bordeaux,IHU Liryc,France","institution_ids":["https://openalex.org/I15057530","https://openalex.org/I4210086115"]},{"raw_affiliation_string":"IHU Liryc, University of Bordeaux, France","institution_ids":["https://openalex.org/I4210086115","https://openalex.org/I15057530"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110360540","display_name":"Bruce H. Smaill","orcid":null},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Bruce H. Smaill","raw_affiliation_strings":["University of Auckland,Auckland Bioengineering Institute,New Zealand","Auckland Bioengineering Institute, University of Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"University of Auckland,Auckland Bioengineering Institute,New Zealand","institution_ids":["https://openalex.org/I154130895"]},{"raw_affiliation_string":"Auckland Bioengineering Institute, University of Auckland, New Zealand","institution_ids":["https://openalex.org/I154130895"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5073737510"],"corresponding_institution_ids":["https://openalex.org/I154130895"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16749069,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2023","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11019","display_name":"Image Enhancement Techniques","score":0.9768000245094299,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11019","display_name":"Image Enhancement Techniques","score":0.9768000245094299,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.9649999737739563,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11105","display_name":"Advanced Image Processing Techniques","score":0.955299973487854,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6152305006980896},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.5045739412307739},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4117748439311981},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.39155930280685425}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6152305006980896},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.5045739412307739},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4117748439311981},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.39155930280685425}],"mesh":[{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc40787.2023.10340357","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/embc40787.2023.10340357","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:38083720","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38083720","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W36323238","https://openalex.org/W1141829639","https://openalex.org/W1550726172","https://openalex.org/W2133665775","https://openalex.org/W2138984876","https://openalex.org/W2143421921","https://openalex.org/W2144559681","https://openalex.org/W2158749167","https://openalex.org/W2167272056","https://openalex.org/W2175408604","https://openalex.org/W2834123982","https://openalex.org/W2888174646","https://openalex.org/W2968591353","https://openalex.org/W3111521801","https://openalex.org/W3167646815","https://openalex.org/W4306411710"],"related_works":["https://openalex.org/W2058170566","https://openalex.org/W2772917594","https://openalex.org/W2755342338","https://openalex.org/W2166024367","https://openalex.org/W3116076068","https://openalex.org/W2229312674","https://openalex.org/W2951359407","https://openalex.org/W2079911747","https://openalex.org/W1969923398","https://openalex.org/W2775347418"],"abstract_inverted_index":{"The":[0,58],"right-ventricular":[1],"(RV)":[2],"outflow":[3],"tract":[4],"(RVOT)":[5],"and":[6,47,49,67,118],"the":[7,10],"transition":[8],"to":[9,81,90],"RV":[11],"free":[12],"wall":[13],"are":[14],"recognized":[15],"sources":[16],"of":[17,73,106,114],"arrhythmia":[18],"in":[19,31],"human":[20,107],"hearts.":[21],"However,":[22],"we":[23],"do":[24],"not":[25],"fully":[26],"understand":[27],"myocardial":[28],"tissue":[29,36,108],"structures":[30,66],"this":[32],"region.":[33],"Human":[34],"heart":[35],"was":[37],"processed":[38],"for":[39,63,120],"optical":[40],"clarity,":[41],"labelled":[42],"with":[43,99],"wheat-germ":[44],"agglutin":[45],"(WGA)":[46],"anti-Cx43,":[48],"imaged":[50],"on":[51],"a":[52],"custom-built":[53],"line":[54],"scanning":[55],"confocal":[56],"microscope.":[57],"3D":[59],"images":[60],"were":[61,71,88],"analyzed":[62],"myocyte":[64],"gross":[65],"cell":[68,86,92],"morphology.":[69,93],"There":[70],"regions":[72],"high":[74],"organization":[75],"as":[76,78,124],"well":[77],"rapid":[79],"changes":[80],"more":[82],"heterogeneous":[83],"regions.":[84],"Preliminary":[85],"segmentations":[87],"used":[89],"estimate":[91],"Observed":[94],"RVOT/RV":[95],"structure":[96,109],"is":[97],"consistent":[98],"known":[100],"arrhythmic":[101],"substrates.Clinical":[102],"Relevance-":[103],"New":[104],"views":[105],"enable":[110],"clearer":[111],"clinical":[112],"understanding":[113],"arrhythmogenic":[115],"activation":[116],"pathways":[117],"targets":[119],"invasive":[121],"treatment":[122],"such":[123],"RF":[125],"ablation.":[126]},"counts_by_year":[],"updated_date":"2025-12-21T01:58:51.020947","created_date":"2025-10-10T00:00:00"}