{"id":"https://openalex.org/W4389542451","doi":"https://doi.org/10.1109/embc40787.2023.10340168","title":"Neural Activity and Information Processing Capacity of Neuronal Culture","display_name":"Neural Activity and Information Processing Capacity of Neuronal Culture","publication_year":2023,"publication_date":"2023-07-24","ids":{"openalex":"https://openalex.org/W4389542451","doi":"https://doi.org/10.1109/embc40787.2023.10340168","pmid":"https://pubmed.ncbi.nlm.nih.gov/38083492"},"language":"en","primary_location":{"id":"doi:10.1109/embc40787.2023.10340168","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/embc40787.2023.10340168","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092089100","display_name":"Dai Akita","orcid":"https://orcid.org/0009-0009-6445-2587"},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Dai Akita","raw_affiliation_strings":["The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656"],"affiliations":[{"raw_affiliation_string":"The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019623919","display_name":"Eisuke Suwa","orcid":null},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eisuke Suwa","raw_affiliation_strings":["The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656"],"affiliations":[{"raw_affiliation_string":"The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012264760","display_name":"Narumitsu Ikeda","orcid":"https://orcid.org/0009-0000-0856-2057"},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Narumitsu Ikeda","raw_affiliation_strings":["The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656"],"affiliations":[{"raw_affiliation_string":"The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014759071","display_name":"Hirokazu Takahashi","orcid":null},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirokazu Takahashi","raw_affiliation_strings":["The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656"],"affiliations":[{"raw_affiliation_string":"The University of Tokyo,Graduate School of Information Science and Technology,Tokyo,Japan,113-8656","institution_ids":["https://openalex.org/I74801974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5092089100"],"corresponding_institution_ids":["https://openalex.org/I74801974"],"apc_list":null,"apc_paid":null,"fwci":0.3497,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.67292642,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"2023","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12611","display_name":"Neural Networks and Reservoir Computing","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12611","display_name":"Neural Networks and Reservoir Computing","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6544314026832581},{"id":"https://openalex.org/keywords/information-processing","display_name":"Information processing","score":0.6235161423683167},{"id":"https://openalex.org/keywords/reservoir-computing","display_name":"Reservoir computing","score":0.5814191102981567},{"id":"https://openalex.org/keywords/grasp","display_name":"GRASP","score":0.5764474272727966},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5301186442375183},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4787580072879791},{"id":"https://openalex.org/keywords/computational-model","display_name":"Computational model","score":0.4517230689525604},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.42594799399375916},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.4245799779891968},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4116200804710388},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3705507814884186},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3105814754962921},{"id":"https://openalex.org/keywords/recurrent-neural-network","display_name":"Recurrent neural network","score":0.2525917887687683},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.13237449526786804},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.09039992094039917}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6544314026832581},{"id":"https://openalex.org/C87868495","wikidata":"https://www.wikidata.org/wiki/Q750843","display_name":"Information processing","level":2,"score":0.6235161423683167},{"id":"https://openalex.org/C135796866","wikidata":"https://www.wikidata.org/wiki/Q7315328","display_name":"Reservoir computing","level":4,"score":0.5814191102981567},{"id":"https://openalex.org/C171268870","wikidata":"https://www.wikidata.org/wiki/Q1486676","display_name":"GRASP","level":2,"score":0.5764474272727966},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5301186442375183},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4787580072879791},{"id":"https://openalex.org/C66024118","wikidata":"https://www.wikidata.org/wiki/Q1122506","display_name":"Computational model","level":2,"score":0.4517230689525604},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.42594799399375916},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.4245799779891968},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4116200804710388},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3705507814884186},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3105814754962921},{"id":"https://openalex.org/C147168706","wikidata":"https://www.wikidata.org/wiki/Q1457734","display_name":"Recurrent neural network","level":3,"score":0.2525917887687683},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.13237449526786804},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.09039992094039917},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001330","descriptor_name":"Electronic Data Processing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc40787.2023.10340168","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/embc40787.2023.10340168","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:38083492","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38083492","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W2079329690","https://openalex.org/W2098746383","https://openalex.org/W2113337191","https://openalex.org/W2211598849","https://openalex.org/W2887258823","https://openalex.org/W2943416613","https://openalex.org/W2972537859","https://openalex.org/W3215054290","https://openalex.org/W3217324605","https://openalex.org/W4304695089","https://openalex.org/W4380302633"],"related_works":["https://openalex.org/W2163296013","https://openalex.org/W2743859443","https://openalex.org/W2326995835","https://openalex.org/W165915117","https://openalex.org/W2059402478","https://openalex.org/W2123347777","https://openalex.org/W4387804363","https://openalex.org/W3192662224","https://openalex.org/W2019547100","https://openalex.org/W4301090890"],"abstract_inverted_index":{"Whether":[0],"artificial":[1],"or":[2,71,162],"living,":[3],"neural":[4,34],"networks":[5,35],"perform":[6],"tremendously":[7],"diverse":[8,66],"kinds":[9],"of":[10,32,40,58,73,81,88,136,145,159,176,197],"information":[11,95],"processing,":[12],"such":[13],"as":[14,60,203],"visual":[15],"feature":[16],"extraction,":[17],"speech":[18],"recognition,":[19],"motor":[20],"control,":[21],"and":[22,124,151,191,200,217],"so":[23],"on.":[24],"Some":[25],"studies":[26],"have":[27],"evaluated":[28,92],"the":[29,38,48,74,79,84,94,109,118,129,133,166,174,177,194,204,213,218,225,236],"computational":[30,86,233],"ability":[31],"living":[33],"based":[36],"on":[37,78],"performances":[39],"specific":[41],"tasks,":[42],"yet":[43],"could":[44],"not":[45],"comprehensively":[46],"grasp":[47],"versatile":[49],"ability.":[50],"In":[51,164],"this":[52,152],"study,":[53],"we":[54,115],"investigated":[55],"dissociated":[56],"culture":[57,90,120,227],"neurons":[59],"a":[61,102,113,142,169],"physical":[62],"reservoir,":[63],"which":[64,99],"generates":[65],"outputs":[67],"through":[68],"linear":[69],"regression,":[70],"readout,":[72],"dynamical":[75],"states.":[76],"Based":[77],"theory":[80],"reservoir":[82,137],"computing,":[83],"potential":[85],"capabilities":[87],"neuronal":[89,119,226,237],"were":[91],"by":[93],"processing":[96],"capacity":[97,144,154],"(IPC),":[98],"indicates":[100],"how":[101],"target":[103],"function":[104],"can":[105],"be":[106],"achieved":[107],"from":[108,235],"given":[110],"dynamics.":[111],"As":[112],"result,":[114],"found":[116],"that":[117,125,212],"exhibited":[121,141],"significant":[122,170],"IPC":[123,126,167],"varied":[127],"with":[128,173,188,224],"inter-step":[130],"interval":[131],"(ISI),":[132],"time":[134,147,220],"step":[135,221],"computing.":[138],"The":[139,184],"cultures":[140],"memory":[143,153],"10":[146],"steps":[148],"for":[149,207],"computation,":[150],"decayed":[155],"at":[156],"an":[157],"ISI":[158,192,206],"5":[160],"ms":[161,202],"shorter.":[163],"addition,":[165],"had":[168],"positive":[171,195],"correlation":[172],"intensity":[175],"evoked":[178,189,198,215],"response":[179,190,199,216],"relative":[180],"to":[181,222,231],"spontaneous":[182],"activity.":[183],"multiple":[185],"regression":[186],"model":[187],"showed":[193],"effect":[196],"30":[201],"best":[205],"IPC.":[208],"These":[209],"results":[210],"suggest":[211],"distinct":[214],"optimal":[219],"interact":[223],"are":[228],"key":[229],"factors":[230],"uncover":[232],"resources":[234],"system.":[238]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2025-12-25T23:11:45.687758","created_date":"2025-10-10T00:00:00"}