{"id":"https://openalex.org/W4389542934","doi":"https://doi.org/10.1109/embc40787.2023.10339941","title":"Ventricular Ejection Fraction and Global Strains in Connection with the Volume Regulation Graph","display_name":"Ventricular Ejection Fraction and Global Strains in Connection with the Volume Regulation Graph","publication_year":2023,"publication_date":"2023-07-24","ids":{"openalex":"https://openalex.org/W4389542934","doi":"https://doi.org/10.1109/embc40787.2023.10339941"},"language":"en","primary_location":{"id":"doi:10.1109/embc40787.2023.10339941","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/embc40787.2023.10339941","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 45th Annual International Conference of the IEEE Engineering in Medicine &amp; Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pure.amsterdamumc.nl/ws/files/156181635/Ventricular-ejection-fraction-and-global-strains-in-connection-with-the-volume-regulation-graph.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009564758","display_name":"Peter L. M. Kerkhof","orcid":"https://orcid.org/0000-0001-9488-633X"},"institutions":[{"id":"https://openalex.org/I4210151833","display_name":"Amsterdam University Medical Centers","ror":"https://ror.org/05grdyy37","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Peter L.M. Kerkhof","raw_affiliation_strings":["Amsterdam University Medical Centers,Dept. Radiology &amp; Nuclear Medicine,Amsterdam,The Netherlands"],"affiliations":[{"raw_affiliation_string":"Amsterdam University Medical Centers,Dept. Radiology &amp; Nuclear Medicine,Amsterdam,The Netherlands","institution_ids":["https://openalex.org/I4210151833"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093460698","display_name":"Jacqueline Y. Bell-Beringer","orcid":null},"institutions":[{"id":"https://openalex.org/I4210139315","display_name":"IC Independent Consulting (Australia)","ror":"https://ror.org/03acet573","country_code":"AU","type":"company","lineage":["https://openalex.org/I4210139315"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jacqueline Y. Bell-Beringer","raw_affiliation_strings":["Cronulla Veterinary Clinic,Sydney,Australia","Cronulla Veterinary Clinic, Sydney, Australia"],"affiliations":[{"raw_affiliation_string":"Cronulla Veterinary Clinic,Sydney,Australia","institution_ids":["https://openalex.org/I4210139315"]},{"raw_affiliation_string":"Cronulla Veterinary Clinic, Sydney, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057706053","display_name":"Rienzi D\u00edaz\u2010Navarro","orcid":"https://orcid.org/0000-0002-5493-0735"},"institutions":[{"id":"https://openalex.org/I79274474","display_name":"University of Valpara\u00edso","ror":"https://ror.org/00h9jrb69","country_code":"CL","type":"education","lineage":["https://openalex.org/I79274474"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Rienzi A. Diaz-Navarro","raw_affiliation_strings":["Universidad de Valparaiso,Dept. of Medicine and the Cardiovascular Physiology Laboratory,Chile","Dept. of Medicine and the Cardiovascular Physiology Laboratory, Universidad de Valparaiso, Chile"],"affiliations":[{"raw_affiliation_string":"Universidad de Valparaiso,Dept. of Medicine and the Cardiovascular Physiology Laboratory,Chile","institution_ids":["https://openalex.org/I79274474"]},{"raw_affiliation_string":"Dept. of Medicine and the Cardiovascular Physiology Laboratory, Universidad de Valparaiso, Chile","institution_ids":["https://openalex.org/I79274474"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087878753","display_name":"John K-J. Li","orcid":null},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John K-J. Li","raw_affiliation_strings":["Rutgers Univ.,Dept. of Biomedical Engineering,Piscataway,NJ,USA","Dept. of Biomedical Engineering, Rutgers Univ., Piscataway, NJ, USA"],"affiliations":[{"raw_affiliation_string":"Rutgers Univ.,Dept. of Biomedical Engineering,Piscataway,NJ,USA","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Dept. of Biomedical Engineering, Rutgers Univ., Piscataway, NJ, USA","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029137777","display_name":"Neal Handly","orcid":"https://orcid.org/0000-0002-9699-5131"},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neal Handly","raw_affiliation_strings":["Drexel University College of Medicine,Dept. Emergency Medicine,Philadelphia,PA,USA","Dept. Emergency Medicine, Drexel University College of Medicine, Philadelphia, PA, USA"],"affiliations":[{"raw_affiliation_string":"Drexel University College of Medicine,Dept. Emergency Medicine,Philadelphia,PA,USA","institution_ids":["https://openalex.org/I72816309"]},{"raw_affiliation_string":"Dept. Emergency Medicine, Drexel University College of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5009564758"],"corresponding_institution_ids":["https://openalex.org/I4210151833"],"apc_list":null,"apc_paid":null,"fwci":0.8807,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.77909979,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ejection-fraction","display_name":"Ejection fraction","score":0.6846238374710083},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.43225809931755066},{"id":"https://openalex.org/keywords/index","display_name":"Index (typography)","score":0.41047632694244385},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.39991119503974915},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3803250789642334},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3704397678375244},{"id":"https://openalex.org/keywords/discrete-mathematics","display_name":"Discrete mathematics","score":0.3431553244590759},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3358737528324127},{"id":"https://openalex.org/keywords/heart-failure","display_name":"Heart failure","score":0.1385701298713684}],"concepts":[{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.6846238374710083},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.43225809931755066},{"id":"https://openalex.org/C2777382242","wikidata":"https://www.wikidata.org/wiki/Q6017816","display_name":"Index (typography)","level":2,"score":0.41047632694244385},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39991119503974915},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3803250789642334},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3704397678375244},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.3431553244590759},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3358737528324127},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.1385701298713684},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/embc40787.2023.10339941","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/embc40787.2023.10339941","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 45th Annual International Conference of the IEEE Engineering in Medicine &amp; Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/bd57bc50-92fa-42be-9c5f-be1e3bc89eb3","is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/bd57bc50-92fa-42be-9c5f-be1e3bc89eb3","pdf_url":"https://pure.amsterdamumc.nl/ws/files/156181635/Ventricular-ejection-fraction-and-global-strains-in-connection-with-the-volume-regulation-graph.pdf","source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Kerkhof, P L M, Bell-Beringer, J Y, Diaz-Navarro, R A, K-J Li, J & Handly, N 2023, 'Ventricular Ejection Fraction and Global Strains in Connection with the Volume Regulation Graph', Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, vol. 2023, pp. 1-4. https://doi.org/10.1109/EMBC40787.2023.10339941","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/bd57bc50-92fa-42be-9c5f-be1e3bc89eb3","is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/bd57bc50-92fa-42be-9c5f-be1e3bc89eb3","pdf_url":"https://pure.amsterdamumc.nl/ws/files/156181635/Ventricular-ejection-fraction-and-global-strains-in-connection-with-the-volume-regulation-graph.pdf","source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Kerkhof, P L M, Bell-Beringer, J Y, Diaz-Navarro, R A, K-J Li, J & Handly, N 2023, 'Ventricular Ejection Fraction and Global Strains in Connection with the Volume Regulation Graph', Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, vol. 2023, pp. 1-4. https://doi.org/10.1109/EMBC40787.2023.10339941","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389542934.pdf"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1989246748","https://openalex.org/W2005928586","https://openalex.org/W2055165826","https://openalex.org/W2145217271","https://openalex.org/W2154291920","https://openalex.org/W2661305832","https://openalex.org/W2783875689","https://openalex.org/W2790015075","https://openalex.org/W2946128786","https://openalex.org/W3196717499","https://openalex.org/W4288467824","https://openalex.org/W4310707846","https://openalex.org/W4315853726"],"related_works":["https://openalex.org/W3183948672","https://openalex.org/W3173606202","https://openalex.org/W3110381201","https://openalex.org/W2948807893","https://openalex.org/W2899084033","https://openalex.org/W2778153218","https://openalex.org/W1531601525","https://openalex.org/W4391375266","https://openalex.org/W4382048704","https://openalex.org/W4400309032"],"abstract_inverted_index":{"Ejection":[0],"fraction":[1],"(EF)":[2],"is":[3,63,163],"traditionally":[4],"considered":[5,275],"useful":[6],"to":[7,32,37,56,100,166,194,248],"infer":[8],"ventricular":[9,259],"function.":[10],"Newer":[11,232],"metrics":[12,233,268],"such":[13,245],"as":[14,86,246],"global":[15,101],"function":[16],"index":[17],"(GFI)":[18],"and":[19,81,104,153,159,196,224,229,237,261],"various":[20],"strains":[21],"add":[22],"supplemental":[23],"diagnostic":[24],"or":[25,140],"prognostic":[26],"value.":[27],"All":[28],"these":[29,209],"candidates":[30],"refer":[31],"dimensionless":[33],"ratios,":[34],"rather":[35],"than":[36],"the":[38,41,47,68,73,77,90,115,120,123,136,212,220,263],"characteristics":[39],"of":[40,79,138,241],"underlying":[42],"components.":[43],"Therefore,":[44],"we":[45,173],"introduced":[46],"volume":[48,54,58,74],"regulation":[49],"graph":[50],"(VRG),":[51],"relating":[52,192],"end-systolic":[53],"(ESV)":[55],"end-diastolic":[57],"(EDV).":[59],"An":[60],"individual":[61],"patient":[62],"then":[64],"uniquely":[65],"defined":[66],"by":[67,135,148],"prevailing":[69],"working":[70,95,264],"point":[71,265],"in":[72,276],"domain.":[75],"Alternatively,":[76],"combination":[78],"EF=(1-ESV/EDV)":[80],"any":[82,279],"suitable":[83],"companion":[84,143,243],"(denoted":[85],"C)":[87],"metric":[88],"(e.g.":[89],"Pythagorean":[91],"mean)":[92],"specifies":[93],"this":[94],"point.An":[96],"expression":[97],"relates":[98],"EF":[99,193],"longitudinal":[102],"(GLS)":[103],"circumferential":[105],"strain":[106],"(GCS):":[107],"ESV/EDV":[108],"=":[109],"(GLS+1)":[110],"(GCS+1)<sup":[111],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[112,169,179],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sup>,":[113],"resembling":[114],"empirical":[116],"regression":[117,172],"equation":[118],"for":[119,181,187,208],"VRG.":[121],"However,":[122],"latter":[124],"has":[125],"a":[126,215,242,250,270],"non-zero":[127],"intercept":[128],"(mL).":[129],"The":[130,161,254],"discrepancy":[131],"can":[132,201],"be":[133,274],"solved":[134],"introduction":[137],"one":[139],"more":[141],"pertinent":[142],"metrics.We":[144],"studied":[145],"96":[146],"patients":[147,203],"cardiac":[149],"magnetic":[150],"resonance":[151],"imaging":[152],"calculated":[154],"EF,":[155],"EFC,":[156],"GFI,":[157,235],"GLS":[158,167,195,236],"GCS.":[160],"GFI":[162],"inversely":[164],"related":[165],"(R<sup":[168],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sup>=0.26).":[170],"For":[171],"found:":[174],"ESV=0.74":[175],"EDV-27.0":[176],"with":[177,204,278],"R<sup":[178],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sup>=0.81":[180],"N=96.":[182],"Similar":[183],"results":[184],"were":[185],"obtained":[186],"echocardiography":[188],"data":[189],"(N=25).":[190],"Graphs":[191],"GCS":[197,238],"indicate":[198],"that":[199,218],"EFC":[200,247],"distinguish":[202],"nearly":[205],"identical":[206],"values":[207],"3":[210],"metrics.Thus,":[211],"VRG":[213,255],"offers":[214],"unifying":[216],"framework":[217],"visualizes":[219],"association":[221],"between":[222],"ESV":[223],"EDV,":[225],"while":[226],"documenting":[227],"iso-EF":[228],"iso-EFC":[230],"trajectories.":[231],"including":[234],"require":[239],"consideration":[240],"variable":[244],"permit":[249],"comprehensive":[251],"analysis.Clinical":[252],"Relevance\u2014":[253],"allows":[256],"insight":[257],"into":[258],"functioning":[260],"illustrates":[262],"concept.":[266],"Companion":[267],"(having":[269],"physical":[271],"dimension)":[272],"should":[273],"conjunction":[277],"traditional":[280],"ratio-based":[281],"index.":[282]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-03-25T13:04:00.132906","created_date":"2023-12-12T00:00:00"}