{"id":"https://openalex.org/W2979298467","doi":"https://doi.org/10.1109/embc.2019.8857934","title":"Convolutional Neural Networks to Detect Pediatric Apnea-Hypopnea Events from Oximetry","display_name":"Convolutional Neural Networks to Detect Pediatric Apnea-Hypopnea Events from Oximetry","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2979298467","doi":"https://doi.org/10.1109/embc.2019.8857934","mag":"2979298467","pmid":"https://pubmed.ncbi.nlm.nih.gov/31946646"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2019.8857934","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8857934","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026434545","display_name":"Fernando Vaquerizo-Villar","orcid":"https://orcid.org/0000-0002-5898-2006"},"institutions":[{"id":"https://openalex.org/I108103353","display_name":"Universidad de Valladolid","ror":"https://ror.org/01fvbaw18","country_code":"ES","type":"education","lineage":["https://openalex.org/I108103353"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Fernando Vaquerizo-Villar","raw_affiliation_strings":["Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain","institution_ids":["https://openalex.org/I108103353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005396204","display_name":"Daniel \u00c1lvarez","orcid":"https://orcid.org/0000-0003-1027-2395"},"institutions":[{"id":"https://openalex.org/I4210158107","display_name":"Hospital Universitario R\u00edo Hortega","ror":"https://ror.org/05jk45963","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210158107"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Daniel Alvarez","raw_affiliation_strings":["Hospital Universitario R\u00edo, Hortega of Valladolid, Spain"],"affiliations":[{"raw_affiliation_string":"Hospital Universitario R\u00edo, Hortega of Valladolid, Spain","institution_ids":["https://openalex.org/I4210158107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038079734","display_name":"David Gozal","orcid":"https://orcid.org/0000-0003-3332-1057"},"institutions":[{"id":"https://openalex.org/I2800649613","display_name":"University of Missouri Health System","ror":"https://ror.org/03yp8z857","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800649613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leila Kheirandish-Gozal","raw_affiliation_strings":["Department of Child Health, The University of Missouri School of Medicine, Columbia, Missouri, USA"],"affiliations":[{"raw_affiliation_string":"Department of Child Health, The University of Missouri School of Medicine, Columbia, Missouri, USA","institution_ids":["https://openalex.org/I2800649613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012085808","display_name":"Gonzalo C. Guti\u00e9rrez\u2010Tobal","orcid":"https://orcid.org/0000-0002-1237-3424"},"institutions":[{"id":"https://openalex.org/I108103353","display_name":"Universidad de Valladolid","ror":"https://ror.org/01fvbaw18","country_code":"ES","type":"education","lineage":["https://openalex.org/I108103353"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Gonzalo C. Gutierrez-Tobal","raw_affiliation_strings":["Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain","institution_ids":["https://openalex.org/I108103353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066312205","display_name":"Ver\u00f3nica Barroso-Garc\u00eda","orcid":"https://orcid.org/0000-0001-5648-206X"},"institutions":[{"id":"https://openalex.org/I108103353","display_name":"Universidad de Valladolid","ror":"https://ror.org/01fvbaw18","country_code":"ES","type":"education","lineage":["https://openalex.org/I108103353"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Veronica Barroso-Garcia","raw_affiliation_strings":["Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain","institution_ids":["https://openalex.org/I108103353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016104659","display_name":"F\u00e9lix del Campo","orcid":"https://orcid.org/0000-0002-4554-2167"},"institutions":[{"id":"https://openalex.org/I4210158107","display_name":"Hospital Universitario R\u00edo Hortega","ror":"https://ror.org/05jk45963","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210158107"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Felix del Campo","raw_affiliation_strings":["Hospital Universitario R\u00edo, Hortega of Valladolid, Spain"],"affiliations":[{"raw_affiliation_string":"Hospital Universitario R\u00edo, Hortega of Valladolid, Spain","institution_ids":["https://openalex.org/I4210158107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043623030","display_name":"David Gozal","orcid":"https://orcid.org/0000-0001-8195-6036"},"institutions":[{"id":"https://openalex.org/I2800649613","display_name":"University of Missouri Health System","ror":"https://ror.org/03yp8z857","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800649613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Gozal","raw_affiliation_strings":["Department of Child Health, The University of Missouri School of Medicine, Columbia, Missouri, USA"],"affiliations":[{"raw_affiliation_string":"Department of Child Health, The University of Missouri School of Medicine, Columbia, Missouri, USA","institution_ids":["https://openalex.org/I2800649613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043513390","display_name":"Roberto Hornero","orcid":"https://orcid.org/0000-0001-9915-2570"},"institutions":[{"id":"https://openalex.org/I108103353","display_name":"Universidad de Valladolid","ror":"https://ror.org/01fvbaw18","country_code":"ES","type":"education","lineage":["https://openalex.org/I108103353"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Roberto Hornero","raw_affiliation_strings":["Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Group, Universidad de Valladolid, Valladolid, Spain","institution_ids":["https://openalex.org/I108103353"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5026434545"],"corresponding_institution_ids":["https://openalex.org/I108103353"],"apc_list":null,"apc_paid":null,"fwci":1.8209,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.85689194,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"2019","issue":null,"first_page":"3555","last_page":"3558"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6647728681564331},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6014758348464966},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5778366923332214},{"id":"https://openalex.org/keywords/apnea","display_name":"Apnea","score":0.5085326433181763},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4440893828868866},{"id":"https://openalex.org/keywords/speech-recognition","display_name":"Speech recognition","score":0.3693541884422302},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3561229705810547},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2376740574836731},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.09099575877189636}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6647728681564331},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6014758348464966},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5778366923332214},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.5085326433181763},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4440893828868866},{"id":"https://openalex.org/C28490314","wikidata":"https://www.wikidata.org/wiki/Q189436","display_name":"Speech recognition","level":1,"score":0.3693541884422302},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3561229705810547},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2376740574836731},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.09099575877189636}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010092","descriptor_name":"Oximetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010092","descriptor_name":"Oximetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010092","descriptor_name":"Oximetry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2019.8857934","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8857934","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:31946646","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31946646","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:uvadoc.uva.es:10324/38010","is_oa":false,"landing_page_url":"http://uvadoc.uva.es/handle/10324/38010","pdf_url":null,"source":{"id":"https://openalex.org/S4306400688","display_name":"University of Valladolid Documentary Repository (University of Valladolid)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I108103353","host_organization_name":"Universidad de Valladolid","host_organization_lineage":["https://openalex.org/I108103353"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/submittedVersion"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/4","score":0.5299999713897705,"display_name":"Quality Education"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W118012049","https://openalex.org/W118211727","https://openalex.org/W2026761333","https://openalex.org/W2100905560","https://openalex.org/W2106512780","https://openalex.org/W2107391591","https://openalex.org/W2108084237","https://openalex.org/W2613839887","https://openalex.org/W2741958707","https://openalex.org/W2750410834","https://openalex.org/W2774336996","https://openalex.org/W2779720004","https://openalex.org/W2802111092","https://openalex.org/W2803427969","https://openalex.org/W2809550229","https://openalex.org/W2811384326","https://openalex.org/W2884525847","https://openalex.org/W2890040152","https://openalex.org/W2895012657","https://openalex.org/W2905540755","https://openalex.org/W2919115771"],"related_works":["https://openalex.org/W4293226380","https://openalex.org/W4321487865","https://openalex.org/W4313906399","https://openalex.org/W4239306820","https://openalex.org/W4391266461","https://openalex.org/W2590798552","https://openalex.org/W2811106690","https://openalex.org/W2947043951","https://openalex.org/W4399188509","https://openalex.org/W4312417841"],"abstract_inverted_index":{"Pediatric":[0],"sleep":[1],"apnea-hypopnea":[2],"syndrome":[3],"(SAHS)":[4],"is":[5,12],"a":[6,62,112,151,166,177],"highly":[7],"prevalent":[8],"breathing":[9],"disorder":[10],"that":[11,194],"related":[13,87],"to":[14,45,88,96,116,176,187,202],"many":[15],"negative":[16],"consequences":[17],"for":[18,33,48,135],"the":[19,46,70,76,105,122,147,160,195,207],"children's":[20],"health":[21],"and":[22,90],"quality":[23],"of":[24,56,72,100,107,129,155,159,170,182,197],"life":[25],"when":[26],"it":[27],"remains":[28],"untreated.":[29],"The":[30],"gold":[31],"standard":[32],"pediatric":[34,214],"SAHS":[35,215],"diagnosis":[36],"(overnight":[37],"polysomnography)":[38],"has":[39,43,59],"several":[40],"limitations,":[41],"which":[42,82],"led":[44],"search":[47],"alternative":[49],"tests.":[50],"In":[51,94],"this":[52,98,136],"sense,":[53],"automated":[54],"analysis":[55],"overnight":[57],"oximetry":[58,208],"emerged":[60],"as":[61],"simplified":[63],"technique.":[64],"Previous":[65],"studies":[66],"have":[67],"focused":[68],"on":[69],"extraction":[71],"ad-hoc":[73],"features":[74],"from":[75,121,146],"blood":[77],"oxygen":[78],"saturation":[79],"(SpO<sub>2</sub>)":[80],"signal,":[81],"may":[83,199],"miss":[84],"useful":[85,201],"information":[86],"apnea":[89],"hypopnea":[91],"(AH)":[92],"events.":[93,190],"order":[95],"overcome":[97],"limitation":[99],"traditional":[101],"approaches,":[102],"we":[103],"propose":[104],"use":[106],"convolutional":[108],"neural":[109],"networks":[110],"(CNN),":[111],"deep":[113],"learning":[114],"technique,":[115],"automatically":[117],"detect":[118,188,203],"AH":[119,189,211],"events":[120,212],"SpO<sub>2</sub>":[123,131,148],"raw":[124],"data.":[125],"CHAT-baseline":[126],"dataset,":[127],"composed":[128],"453":[130],"recordings,":[132],"was":[133,141,174],"used":[134],"purpose.":[137],"A":[138],"CNN":[139,161,198],"model":[140,173],"trained":[142],"using":[143,150,165],"60-s":[144],"segments":[145],"signal":[149,209],"training":[152],"set":[153,168,180],"(50%":[154],"subjects).":[156,171],"Optimum":[157],"hyperparameters":[158],"architecture":[162],"were":[163],"obtained":[164],"validation":[167],"(25%":[169,181],"This":[172],"applied":[175],"third":[178],"test":[179],"subjects),":[183],"reaching":[184],"93.6%":[185],"accuracy":[186],"These":[191],"results":[192],"suggest":[193],"application":[196],"be":[200],"changes":[204],"produced":[205],"in":[206,213],"by":[210],"patients.":[216]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":5}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}