{"id":"https://openalex.org/W2979880303","doi":"https://doi.org/10.1109/embc.2019.8857316","title":"Slow-Fast Duffing Neural Mass Model","display_name":"Slow-Fast Duffing Neural Mass Model","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2979880303","doi":"https://doi.org/10.1109/embc.2019.8857316","mag":"2979880303","pmid":"https://pubmed.ncbi.nlm.nih.gov/31945864"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2019.8857316","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8857316","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://discovery.ucl.ac.uk/10083150/1/EMBC19_0854_FI.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032340394","display_name":"Amirhossein Jafarian","orcid":"https://orcid.org/0000-0001-9547-7941"},"institutions":[{"id":"https://openalex.org/I165524941","display_name":"Wellcome Centre for Human Neuroimaging","ror":"https://ror.org/02704qw51","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I165524941","https://openalex.org/I45129253","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Amirhossein Jafarian","raw_affiliation_strings":["The Wellcome Center For Human Neuroimaging, University Collage London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Wellcome Center For Human Neuroimaging, University Collage London, United Kingdom","institution_ids":["https://openalex.org/I165524941"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066512588","display_name":"Dean R. Freestone","orcid":"https://orcid.org/0000-0003-2411-5358"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Dean R. Freestone","raw_affiliation_strings":["Dept. Medicine, The University of Melbourne, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. Medicine, The University of Melbourne, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035230630","display_name":"Dragan Ne\u0161i\u0107","orcid":"https://orcid.org/0000-0001-7944-0241"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Dragan Nesic","raw_affiliation_strings":["Dept. Electrical & Electronic Engineering, The University of Melbourne, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. Electrical & Electronic Engineering, The University of Melbourne, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014100961","display_name":"David B. Grayden","orcid":"https://orcid.org/0000-0002-5497-7234"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David B. Grayden","raw_affiliation_strings":["Dept. Biomedical Engineering, The University of Melbourne, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. Biomedical Engineering, The University of Melbourne, VIC, Australia","institution_ids":["https://openalex.org/I165779595"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2019","issue":null,"first_page":"142","last_page":"145"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10320","display_name":"Neural Networks and Applications","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5072471499443054},{"id":"https://openalex.org/keywords/genetic-algorithm","display_name":"Genetic algorithm","score":0.5007061958312988},{"id":"https://openalex.org/keywords/kalman-filter","display_name":"Kalman filter","score":0.4943225383758545},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.4650116562843323},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.44993025064468384},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.40405911207199097},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.40074822306632996},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3576418161392212},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2553101181983948},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.23678293824195862},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.11890894174575806},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.10603219270706177}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5072471499443054},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.5007061958312988},{"id":"https://openalex.org/C157286648","wikidata":"https://www.wikidata.org/wiki/Q846780","display_name":"Kalman filter","level":2,"score":0.4943225383758545},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.4650116562843323},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.44993025064468384},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.40405911207199097},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.40074822306632996},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3576418161392212},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2553101181983948},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.23678293824195862},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.11890894174575806},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.10603219270706177},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2019.8857316","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8857316","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:31945864","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31945864","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10083150","is_oa":true,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10083150/","pdf_url":"https://discovery.ucl.ac.uk/10083150/1/EMBC19_0854_FI.pdf","source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"In: Proceedings of the 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). (pp. pp. 142-145). IEEE: Berlin, Germany. (2019)","raw_type":"Proceedings paper"}],"best_oa_location":{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10083150","is_oa":true,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10083150/","pdf_url":"https://discovery.ucl.ac.uk/10083150/1/EMBC19_0854_FI.pdf","source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"In: Proceedings of the 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). (pp. pp. 142-145). IEEE: Berlin, Germany. (2019)","raw_type":"Proceedings paper"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2979880303.pdf"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W141187532","https://openalex.org/W639349315","https://openalex.org/W1966800524","https://openalex.org/W2008058125","https://openalex.org/W2019210515","https://openalex.org/W2036522227","https://openalex.org/W2037541476","https://openalex.org/W2052394872","https://openalex.org/W2055155319","https://openalex.org/W2070765152","https://openalex.org/W2080955301","https://openalex.org/W2085677445","https://openalex.org/W2124202837","https://openalex.org/W2131582127","https://openalex.org/W2136688120","https://openalex.org/W2402340177","https://openalex.org/W4244746866"],"related_works":["https://openalex.org/W1580685205","https://openalex.org/W1982160337","https://openalex.org/W2760382975","https://openalex.org/W1971380437","https://openalex.org/W1983548084","https://openalex.org/W2160609742","https://openalex.org/W2141691317","https://openalex.org/W2110846987","https://openalex.org/W2349716249","https://openalex.org/W1985063657"],"abstract_inverted_index":{"Epileptic":[0],"seizures":[1,118],"may":[2],"be":[3],"initiated":[4],"by":[5,10,57,79],"random":[6,126],"neuronal":[7],"fluctuations":[8,128],"and/or":[9],"pathological":[11,99,130],"slow":[12,81,133],"regulatory":[13],"dynamics":[14,82,160],"of":[15,51,63,70,90,94,101,132,138,161],"ion":[16,102],"currents.":[17,103],"This":[18],"paper":[19],"presents":[20],"extensions":[21],"to":[22,31,47,60,84,97,115,125,158],"the":[23,41,71,74,95,110],"Jansen":[24],"and":[25,87,116,136,151],"Rit":[26],"neural":[27,68],"mass":[28],"model":[29],"(JRNMM)":[30],"replicate":[32,98],"paroxysmal":[33,165],"transitions":[34,114],"in":[35,66],"intracranial":[36],"electroencephalogram":[37],"(iEEG)":[38],"recordings.":[39],"First,":[40],"Duffing":[42],"NMM":[43],"(DNMM)":[44],"is":[45,55,77,107],"introduced":[46,78],"emulate":[48],"stochastic":[49],"generators":[50],"seizures.":[52],"The":[53],"DNMM":[54,76,96,112],"constructed":[56],"applying":[58],"perturbations":[59],"linear":[61],"models":[62],"synaptic":[64],"transmission":[65],"each":[67],"population":[69],"JRNMM.":[72],"Then,":[73],"slow-fast":[75,111],"considering":[80],"(relative":[83],"membrane":[85],"potential":[86],"firing":[88],"rate)":[89],"some":[91],"internal":[92],"parameters":[93],"evolution":[100,131],"Through":[104],"simulation,":[105],"it":[106],"illustrated":[108],"that":[109,121],"exhibits":[113],"from":[117],"with":[119,164],"etiologies":[120],"are":[122,156],"linked":[123],"either":[124],"input":[127],"or":[129],"states.":[134],"Estimation":[135],"optimization":[137],"a":[139,145,152],"log":[140],"likelihood":[141],"function":[142],"(LLF)":[143],"using":[144],"continuous-discrete":[146],"unscented":[147],"Kalman":[148],"filter":[149],"(CD-UKF)":[150],"genetic":[153],"algorithm":[154],"(GA)":[155],"performed":[157],"capture":[159],"iEEG":[162],"data":[163],"transitions.":[166]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-07-19T07:52:34.831488","created_date":"2025-10-10T00:00:00"}