{"id":"https://openalex.org/W2980188943","doi":"https://doi.org/10.1109/embc.2019.8856405","title":"Cross-Frequency Coupling Features of Postictal Generalized EEG Suppression State","display_name":"Cross-Frequency Coupling Features of Postictal Generalized EEG Suppression State","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2980188943","doi":"https://doi.org/10.1109/embc.2019.8856405","mag":"2980188943","pmid":"https://pubmed.ncbi.nlm.nih.gov/31947015"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2019.8856405","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8856405","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070449503","display_name":"Vasily Grigorovsky","orcid":"https://orcid.org/0000-0003-1002-3073"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Vasily Grigorovsky","raw_affiliation_strings":["Institute of Biomaterials and Biomedical Engineering, University of Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Institute of Biomaterials and Biomedical Engineering, University of Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050626491","display_name":"J. Martin del Campo","orcid":null},"institutions":[{"id":"https://openalex.org/I2799337515","display_name":"Toronto Western Hospital","ror":"https://ror.org/03qv8yq19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2799337515"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jose Martin del Campo","raw_affiliation_strings":["Department of Neurology, Toronto Western Hospital, Toronto, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Neurology, Toronto Western Hospital, Toronto, Canada","institution_ids":["https://openalex.org/I2799337515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049862858","display_name":"Yotin Chinvarun","orcid":"https://orcid.org/0000-0003-3630-5423"},"institutions":[{"id":"https://openalex.org/I4210087968","display_name":"Phramongkutklao Hospital","ror":"https://ror.org/007h1qz76","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4210087968"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Yotin Chinvarun","raw_affiliation_strings":["Comprehensive Epilepsy Program and Neurology Unit, Phramongkutklao Hospital, Bangkok, Thailand"],"affiliations":[{"raw_affiliation_string":"Comprehensive Epilepsy Program and Neurology Unit, Phramongkutklao Hospital, Bangkok, Thailand","institution_ids":["https://openalex.org/I4210087968"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044113968","display_name":"Peter L. Carlen","orcid":"https://orcid.org/0000-0002-3339-8102"},"institutions":[{"id":"https://openalex.org/I1325899441","display_name":"University Health Network","ror":"https://ror.org/042xt5161","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Peter Carlen","raw_affiliation_strings":["Toronto Western Research Institute, University Health Network, Toronto, Canada"],"affiliations":[{"raw_affiliation_string":"Toronto Western Research Institute, University Health Network, Toronto, Canada","institution_ids":["https://openalex.org/I1325899441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000047757","display_name":"Berj L. Bardakjian","orcid":"https://orcid.org/0000-0001-9969-4775"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Berj L. Bardakjian","raw_affiliation_strings":["Institute of Biomaterials and Biomedical Engineering, University of Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Institute of Biomaterials and Biomedical Engineering, University of Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5070449503"],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":null,"apc_paid":null,"fwci":0.1216,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.47863061,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"59","issue":null,"first_page":"5137","last_page":"5140"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.7155247926712036},{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.6797668933868408},{"id":"https://openalex.org/keywords/coupling","display_name":"Coupling (piping)","score":0.562359094619751},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.43379876017570496},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.4021882712841034},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3989686369895935},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.34633249044418335},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.12285703420639038}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.7155247926712036},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.6797668933868408},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.562359094619751},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.43379876017570496},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4021882712841034},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3989686369895935},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.34633249044418335},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.12285703420639038},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069280","descriptor_name":"Electrocorticography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069280","descriptor_name":"Electrocorticography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069280","descriptor_name":"Electrocorticography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012640","descriptor_name":"Seizures","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2019.8856405","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8856405","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:31947015","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31947015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.800000011920929}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1519547058","https://openalex.org/W1642958044","https://openalex.org/W1975190957","https://openalex.org/W1976804176","https://openalex.org/W2079476861","https://openalex.org/W2089752636","https://openalex.org/W2112575160","https://openalex.org/W2524523348","https://openalex.org/W2558902621","https://openalex.org/W2569979697","https://openalex.org/W2600642036","https://openalex.org/W2757400167","https://openalex.org/W2790716321","https://openalex.org/W2793411159","https://openalex.org/W2899069789"],"related_works":["https://openalex.org/W2395385109","https://openalex.org/W2773633178","https://openalex.org/W2080101436","https://openalex.org/W2802335767","https://openalex.org/W2922348724","https://openalex.org/W2356350882","https://openalex.org/W4388090985","https://openalex.org/W200322357","https://openalex.org/W1545074592","https://openalex.org/W2275559830"],"abstract_inverted_index":{"In":[0,73],"patients":[1,172],"with":[2,148],"epilepsy,":[3],"convulsive":[4],"seizures":[5],"are":[6,229,240],"often":[7],"followed":[8],"by":[9,18],"a":[10,25,201,205],"postictal":[11,249],"generalized":[12],"EEG":[13,59],"suppression":[14],"(PGES)":[15],"state":[16,30,97],"characterized":[17],"reduced":[19],"background":[20],"activity.":[21,46],"Recent":[22],"studies":[23],"found":[24,86,134,158],"correlation":[26],"between":[27,145,188],"seizure":[28,54,82,215],"termination":[29],"and":[31,34,92,115,122,126,190,237],"PGES":[32,37,91,121,155,189,236],"duration,":[33],"suggested":[35],"that":[36,49,135,159,227,233,238,243],"is":[38],"the":[39,42,79,87,99,111,128,141,146,154,163,174,177],"result":[40],"of":[41,44,65,90,98,105,113,130,143,162,180],"cessation":[43],"neuronal":[45],"To":[47],"test":[48],"assertion,":[50],"we":[51,109,195],"investigated":[52],"ten":[53],"records":[55],"obtained":[56],"from":[57,61,204,214],"intracranial":[58],"(iEEG)":[60],"six":[62],"patients,":[63,164],"four":[64],"which":[66],"had":[67],"Engel":[68,169],"Class":[69,170],"1":[70,171],"surgical":[71],"outcome.":[72],"each":[74],"case":[75],"expert":[76],"neurologists":[77],"identified":[78,110],"most":[80],"likely":[81],"onset":[83,216],"electrode.":[84],"We":[85,133,157],"iEEG":[88],"equivalent":[89],"an":[93,138],"artifact-free":[94],"preictal":[95,123,191],"quiescent":[96,124,192],"same":[100],"window":[101],"size.":[102],"Using":[103],"index":[104],"cross-frequency":[106],"coupling":[107,114,144,231],"(ICFC)":[108],"degree":[112,142],"dominant":[116],"frequency":[117,151,230],"bands":[118,152],"involved":[119],"in":[120,140,153,168,176,223,245],"states,":[125],"quantified":[127,178],"areas":[129],"high":[131,149,181],"ICFC.":[132],"there":[136,228,239],"was":[137,183,203,213],"increase":[139],"0.5-1.5Hz":[147],"gamma":[150],"states.":[156,193],"among":[160],"all":[161],"as":[165,167],"well":[166],"specifically,":[173],"change":[175],"area":[179],"ICFC":[182,221],"significant":[184],"(p":[185],"<;":[186],"0.05)":[187],"Furthermore,":[194],"were":[196],"able":[197],"to":[198],"identify":[199,235],"whether":[200,211],"recording":[202],"depth":[206],"or":[207,210,218],"subdural":[208],"electrode,":[209],"it":[212],"zone":[217],"not":[219],"using":[220],"markers":[222,232],"PGES.":[224],"This":[225],"suggests":[226],"successfully":[234],"underlying":[241],"dynamics":[242],"occur":[244],"this":[246],"seemingly":[247],"quiet":[248],"state.":[250]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}