{"id":"https://openalex.org/W2979386575","doi":"https://doi.org/10.1109/embc.2019.8856300","title":"Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics \u2013 Population Specific Model","display_name":"Investigation of the Optic Nerve Head Morphology Influence to the Optic Nerve Head Biomechanics \u2013 Population Specific Model","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2979386575","doi":"https://doi.org/10.1109/embc.2019.8856300","mag":"2979386575","pmid":"https://pubmed.ncbi.nlm.nih.gov/31947070"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2019.8856300","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8856300","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025930898","display_name":"Match W. L. Ko","orcid":"https://orcid.org/0000-0002-1219-213X"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Match W.L. Ko","raw_affiliation_strings":["Department of Mechanical Engineering, The University of Hong Kong, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045250253","display_name":"Chrissi C. C. Lai","orcid":null},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Chrissi C. C. Lai","raw_affiliation_strings":["Department of Mechanical Engineering, The University of Hong Kong, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067490116","display_name":"Patrick C.K. Ng","orcid":null},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Patrick C.K. Ng","raw_affiliation_strings":["Department of Mechanical Engineering, The University of Hong Kong, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007636085","display_name":"Bkc Chow","orcid":"https://orcid.org/0000-0003-3390-0307"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Billy H. Y. Chow","raw_affiliation_strings":["Department of Mechanical Engineering, The University of Hong Kong, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033561081","display_name":"Moses J.S. Woo","orcid":null},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Moses J.S. Woo","raw_affiliation_strings":["Department of Mechanical Engineering, The University of Hong Kong, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068349041","display_name":"Kingsley H. C. Yim","orcid":null},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Kingsley H. C. Yim","raw_affiliation_strings":["Department of Mechanical Engineering, The University of Hong Kong, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, The University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082668920","display_name":"Jong Kim","orcid":"https://orcid.org/0000-0002-8796-3832"},"institutions":[{"id":"https://openalex.org/I60559429","display_name":"Nazarbayev University","ror":"https://ror.org/052bx8q98","country_code":"KZ","type":"education","lineage":["https://openalex.org/I60559429"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Jong R. Kim","raw_affiliation_strings":["Civil and Environmental Engineering Department, Nazarbayev University, Astana, Kazakhstan"],"affiliations":[{"raw_affiliation_string":"Civil and Environmental Engineering Department, Nazarbayev University, Astana, Kazakhstan","institution_ids":["https://openalex.org/I60559429"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5025930898"],"corresponding_institution_ids":["https://openalex.org/I889458895"],"apc_list":null,"apc_paid":null,"fwci":0.861,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.73663013,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2019","issue":null,"first_page":"5374","last_page":"5377"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11291","display_name":"Intraocular Surgery and Lenses","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optic-nerve","display_name":"Optic nerve","score":0.8405303955078125},{"id":"https://openalex.org/keywords/glaucoma","display_name":"Glaucoma","score":0.7402565479278564},{"id":"https://openalex.org/keywords/intraocular-pressure","display_name":"Intraocular pressure","score":0.5049331784248352},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.45419058203697205},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.42903849482536316},{"id":"https://openalex.org/keywords/shear-stress","display_name":"Shear stress","score":0.4222487211227417},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4078204333782196},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.3686749339103699}],"concepts":[{"id":"https://openalex.org/C2780837183","wikidata":"https://www.wikidata.org/wiki/Q186029","display_name":"Optic nerve","level":2,"score":0.8405303955078125},{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.7402565479278564},{"id":"https://openalex.org/C2781092963","wikidata":"https://www.wikidata.org/wiki/Q650050","display_name":"Intraocular pressure","level":2,"score":0.5049331784248352},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.45419058203697205},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.42903849482536316},{"id":"https://openalex.org/C21141959","wikidata":"https://www.wikidata.org/wiki/Q657936","display_name":"Shear stress","level":2,"score":0.4222487211227417},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4078204333782196},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3686749339103699},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007429","descriptor_name":"Intraocular Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009901","descriptor_name":"Optic Nerve Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009901","descriptor_name":"Optic Nerve Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009901","descriptor_name":"Optic Nerve Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013314","descriptor_name":"Stress, Mechanical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013314","descriptor_name":"Stress, Mechanical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013314","descriptor_name":"Stress, Mechanical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014065","descriptor_name":"Tonometry, Ocular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014065","descriptor_name":"Tonometry, Ocular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014065","descriptor_name":"Tonometry, Ocular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2019.8856300","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2019.8856300","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:31947070","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31947070","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W105203448","https://openalex.org/W189392931","https://openalex.org/W302579078","https://openalex.org/W569823040","https://openalex.org/W1667265675","https://openalex.org/W1964458657","https://openalex.org/W1965358032","https://openalex.org/W1982537788","https://openalex.org/W1999641044","https://openalex.org/W2000600447","https://openalex.org/W2006072192","https://openalex.org/W2009930015","https://openalex.org/W2037444248","https://openalex.org/W2078332202","https://openalex.org/W2085288497","https://openalex.org/W2163925135","https://openalex.org/W2171240327","https://openalex.org/W2222872302","https://openalex.org/W2592759155","https://openalex.org/W2761604622","https://openalex.org/W2915001283","https://openalex.org/W6689130563"],"related_works":["https://openalex.org/W23766661","https://openalex.org/W74963343","https://openalex.org/W2109488902","https://openalex.org/W2239285033","https://openalex.org/W2056344052","https://openalex.org/W3118872369","https://openalex.org/W2975388422","https://openalex.org/W2075308789","https://openalex.org/W1942675811","https://openalex.org/W2300330446"],"abstract_inverted_index":{"Glaucoma":[0],"is":[1,66],"an":[2,84],"eye":[3],"disorder":[4],"potentially":[5],"leading":[6],"to":[7,54,63,110,146],"permanent":[8],"blindness":[9],"through":[10,48],"the":[11,17,30,36,64,67,89,118,135,152,159],"damage":[12],"of":[13,26,60,91,117,141,148,155,161],"optic":[14,18,27,45],"nerves":[15,46],"at":[16,100],"nerve":[19,28],"head":[20],"(ONH).":[21],"As":[22],"a":[23,39],"critical":[24,40],"region":[25],"damage,":[29],"porous":[31],"Lamina":[32],"Cribrosa":[33],"(LC)":[34],"in":[35,42,52,69,87,170],"ONH":[37],"plays":[38],"role":[41],"determining":[43,88],"whether":[44],"passing":[47],"will":[49],"experience":[50],"apoptosis":[51],"response":[53,109],"shear":[55,61,111,132,163],"stress.":[56],"The":[57,96,139],"primary":[58],"cause":[59],"stress":[62,112,133,164],"LC":[65,80,104,124,137,142,156],"increase":[68],"intraocular":[70],"pressure":[71],"(IOP).":[72],"Since":[73],"morphology":[74,81,106,143,157],"governs":[75],"how":[76,102],"mechanical":[77],"stresses":[78],"distributes,":[79],"could":[82,126],"be":[83,127],"important":[85],"factor":[86],"risks":[90],"glaucoma":[92],"development":[93],"and":[94,165],"progression.":[95],"current":[97,119],"project":[98],"aims":[99],"investigating":[101],"anterior":[103,136],"surface":[105],"impacts":[107],"its":[108],"caused":[113],"by":[114],"IOP.":[115,149],"Results":[116],"study":[120],"show":[121],"that":[122,147],"steeper":[123],"morphologies":[125],"associated":[128],"with":[129],"increased":[130],"average":[131],"on":[134,158],"surface.":[138],"effect":[140],"was":[144],"comparable":[145],"This":[150],"highlights":[151],"potential":[153],"significance":[154],"distribution":[160],"IOP-induced":[162],"calls":[166],"for":[167],"further":[168],"investigation":[169],"this":[171],"area.":[172]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}