{"id":"https://openalex.org/W2898875071","doi":"https://doi.org/10.1109/embc.2018.8513583","title":"Ex Vivo Assessment of Multiple Parameters in High Intensity Focused Ultrasound","display_name":"Ex Vivo Assessment of Multiple Parameters in High Intensity Focused Ultrasound","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2898875071","doi":"https://doi.org/10.1109/embc.2018.8513583","mag":"2898875071","pmid":"https://pubmed.ncbi.nlm.nih.gov/30441631"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513583","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513583","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007992604","display_name":"Virginia Simoni","orcid":null},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V. Simoni","raw_affiliation_strings":["Scuola Superiore Sant'Anna, Pisa, Toscana, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scuola Superiore Sant'Anna, Pisa, Toscana, IT","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073038474","display_name":"Andrea Cafarelli","orcid":"https://orcid.org/0000-0002-0626-8652"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Cafarelli","raw_affiliation_strings":["Scuola Superiore Sant'Anna, Pisa, Toscana, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scuola Superiore Sant'Anna, Pisa, Toscana, IT","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077267455","display_name":"Selene Tognarelli","orcid":"https://orcid.org/0000-0003-1135-8625"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Tognarelli","raw_affiliation_strings":["Scuola Superiore Sant'Anna, Pisa, Toscana, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scuola Superiore Sant'Anna, Pisa, Toscana, IT","institution_ids":["https://openalex.org/I162290304"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048610531","display_name":"Arianna Menciassi","orcid":"https://orcid.org/0000-0001-6348-1081"},"institutions":[{"id":"https://openalex.org/I162290304","display_name":"Scuola Superiore Sant'Anna","ror":"https://ror.org/025602r80","country_code":"IT","type":"education","lineage":["https://openalex.org/I162290304"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Menciassi","raw_affiliation_strings":["Scuola Superiore Sant'Anna, Pisa, Toscana, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scuola Superiore Sant'Anna, Pisa, Toscana, IT","institution_ids":["https://openalex.org/I162290304"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I162290304"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2018","issue":null,"first_page":"5705","last_page":"5708"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11842","display_name":"Ultrasound and Cavitation Phenomena","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-intensity-focused-ultrasound","display_name":"High-intensity focused ultrasound","score":0.82720947265625},{"id":"https://openalex.org/keywords/cavitation","display_name":"Cavitation","score":0.8111146092414856},{"id":"https://openalex.org/keywords/ex-vivo","display_name":"Ex vivo","score":0.6858376860618591},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6532491445541382},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.6525865793228149},{"id":"https://openalex.org/keywords/duty-cycle","display_name":"Duty cycle","score":0.6334106922149658},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.6210912466049194},{"id":"https://openalex.org/keywords/therapeutic-ultrasound","display_name":"Therapeutic ultrasound","score":0.5645052790641785},{"id":"https://openalex.org/keywords/ablation","display_name":"Ablation","score":0.5457755923271179},{"id":"https://openalex.org/keywords/thermocouple","display_name":"Thermocouple","score":0.5111947655677795},{"id":"https://openalex.org/keywords/ultrasonic-sensor","display_name":"Ultrasonic sensor","score":0.41321977972984314},{"id":"https://openalex.org/keywords/acoustics","display_name":"Acoustics","score":0.2945687770843506},{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.2936522960662842},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.21144849061965942},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.20544111728668213},{"id":"https://openalex.org/keywords/power","display_name":"Power (physics)","score":0.14729121327400208},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.08432784676551819}],"concepts":[{"id":"https://openalex.org/C2777365067","wikidata":"https://www.wikidata.org/wiki/Q564897","display_name":"High-intensity focused ultrasound","level":3,"score":0.82720947265625},{"id":"https://openalex.org/C207057113","wikidata":"https://www.wikidata.org/wiki/Q201666","display_name":"Cavitation","level":2,"score":0.8111146092414856},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.6858376860618591},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6532491445541382},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.6525865793228149},{"id":"https://openalex.org/C199822604","wikidata":"https://www.wikidata.org/wiki/Q557120","display_name":"Duty cycle","level":3,"score":0.6334106922149658},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6210912466049194},{"id":"https://openalex.org/C2779727089","wikidata":"https://www.wikidata.org/wiki/Q564875","display_name":"Therapeutic ultrasound","level":3,"score":0.5645052790641785},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.5457755923271179},{"id":"https://openalex.org/C168068576","wikidata":"https://www.wikidata.org/wiki/Q190241","display_name":"Thermocouple","level":2,"score":0.5111947655677795},{"id":"https://openalex.org/C81288441","wikidata":"https://www.wikidata.org/wiki/Q20736125","display_name":"Ultrasonic sensor","level":2,"score":0.41321977972984314},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.2945687770843506},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.2936522960662842},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.21144849061965942},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20544111728668213},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.14729121327400208},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.08432784676551819},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000162","descriptor_name":"Acoustics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000162","descriptor_name":"Acoustics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000162","descriptor_name":"Acoustics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013010","descriptor_name":"Sonication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013010","descriptor_name":"Sonication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013010","descriptor_name":"Sonication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057086","descriptor_name":"High-Intensity Focused Ultrasound Ablation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057086","descriptor_name":"High-Intensity Focused Ultrasound Ablation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057086","descriptor_name":"High-Intensity Focused Ultrasound Ablation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2018.8513583","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513583","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30441631","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30441631","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:www.iris.sssup.it:11382/527056","is_oa":false,"landing_page_url":"http://hdl.handle.net/11382/527056","pdf_url":null,"source":{"id":"https://openalex.org/S4377196376","display_name":"CINECA IRIS Institutional Research Information System (Sant'Anna School of Advanced Studies)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I162290304","host_organization_name":"Scuola Superiore Sant'Anna","host_organization_lineage":["https://openalex.org/I162290304"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.44999998807907104}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W7961645","https://openalex.org/W1964657861","https://openalex.org/W2003054616","https://openalex.org/W2025771207","https://openalex.org/W2025774845","https://openalex.org/W2055469237","https://openalex.org/W2067069795","https://openalex.org/W2067191069","https://openalex.org/W2099319475","https://openalex.org/W2100270269","https://openalex.org/W2113546018","https://openalex.org/W2122067998","https://openalex.org/W2131875975","https://openalex.org/W2323169148","https://openalex.org/W2599884849","https://openalex.org/W2621027609","https://openalex.org/W4248364551"],"related_works":["https://openalex.org/W2076246675","https://openalex.org/W1965434091","https://openalex.org/W2765805406","https://openalex.org/W3214615448","https://openalex.org/W2354674897","https://openalex.org/W3182181559","https://openalex.org/W3187668469","https://openalex.org/W2108920393","https://openalex.org/W2775034289","https://openalex.org/W2088545962"],"abstract_inverted_index":{"High":[0],"Intensity":[1],"Focused":[2],"Ultrasound":[3],"(HIFU)":[4],"is":[5,39,54],"a":[6,11,60,91,107,146,155],"very":[7],"promising":[8],"technology":[9],"for":[10,25,132,138],"non-invasive":[12],"treatment":[13],"of":[14,51,59,63,149,157],"several":[15],"pathologies,":[16],"especially":[17],"in":[18,35,71,96],"oncology.":[19],"However,":[20],"optimizing":[21],"the":[22,28,36,57,97],"stimulation":[23],"parameters":[24,143],"better":[26,139],"tuning":[27,140],"induced":[29,70],"lethal":[30],"effects":[31],"(thermal":[32],"and/or":[33],"mechanical)":[34],"targeted":[37],"area":[38],"not":[40,45],"trivial":[41],"and":[42,67,83,101,112,121],"it":[43],"has":[44],"been":[46],"achieved":[47],"yet.":[48],"The":[49,124],"aim":[50],"this":[52],"study":[53],"to":[55,144],"present":[56],"results":[58,126],"combined":[61],"analysis":[62],"temperature,":[64],"acoustic":[65],"cavitation":[66,103,109],"lesion":[68,113],"geometry":[69],"ex":[72],"vivo":[73],"tissues":[74],"during":[75],"HIFU":[76,141],"procedures":[77],"by":[78],"varying":[79],"power,":[80],"sonication":[81],"time":[82],"duty":[84],"cycle.":[85],"Temperature":[86],"rise":[87],"was":[88,115],"analyzed":[89],"using":[90,106,117],"thin":[92],"wire":[93],"thermocouple":[94],"embedded":[95],"sonicated":[98],"tissue;":[99],"stable":[100],"inertial":[102],"were":[104],"measured":[105],"passive":[108],"detector":[110],"(PCD),":[111],"volume":[114],"assessed":[116],"both":[118],"ultrasound":[119],"imaging":[120],"optical":[122],"visualization.":[123],"obtained":[125],"may":[127],"represent":[128],"an":[129],"important":[130],"guideline":[131],"clinical":[133],"treatments,":[134],"providing":[135],"useful":[136],"nformation":[137],"operational":[142],"induce":[145],"desired":[147],"type":[148],"ablation":[150],"(i.e.":[151],"thermal,":[152],"mechanical":[153],"or":[154],"combination":[156],"both).":[158]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}