{"id":"https://openalex.org/W2899352846","doi":"https://doi.org/10.1109/embc.2018.8513564","title":"Key Marker Selection for the Detection of Early Parkinson\u2019 s Disease using Importance-Driven Models","display_name":"Key Marker Selection for the Detection of Early Parkinson\u2019 s Disease using Importance-Driven Models","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2899352846","doi":"https://doi.org/10.1109/embc.2018.8513564","mag":"2899352846","pmid":"https://pubmed.ncbi.nlm.nih.gov/30441727"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513564","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513564","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063594676","display_name":"Chun Xiao","orcid":"https://orcid.org/0000-0002-0725-1107"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Chun Xiao","raw_affiliation_strings":["The University of Sydney, Sydney, NSW, AU"],"affiliations":[{"raw_affiliation_string":"The University of Sydney, Sydney, NSW, AU","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053146492","display_name":"Yingchao Liu","orcid":"https://orcid.org/0000-0002-6656-2511"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingchao Liu","raw_affiliation_strings":["Shandong University, Jinan, Shandong, CN"],"affiliations":[{"raw_affiliation_string":"Shandong University, Jinan, Shandong, CN","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068891693","display_name":"Dagan Feng","orcid":"https://orcid.org/0000-0002-3381-214X"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David Dagan Feng","raw_affiliation_strings":["The University of Sydney, Sydney, NSW, AU"],"affiliations":[{"raw_affiliation_string":"The University of Sydney, Sydney, NSW, AU","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046614213","display_name":"Xiuying Wang","orcid":"https://orcid.org/0000-0001-7160-5929"},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Xiuying Wang","raw_affiliation_strings":["The University of Sydney, Sydney, NSW, AU"],"affiliations":[{"raw_affiliation_string":"The University of Sydney, Sydney, NSW, AU","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5063594676"],"corresponding_institution_ids":["https://openalex.org/I129604602"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.17399471,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"2018","issue":null,"first_page":"6100","last_page":"6103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10863","display_name":"Voice and Speech Disorders","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10863","display_name":"Voice and Speech Disorders","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12707","display_name":"Vehicle License Plate Recognition","score":0.9483000040054321,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9405999779701233,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/modalities","display_name":"Modalities","score":0.7614762783050537},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.6805809736251831},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6725335717201233},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6253837943077087},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6103575229644775},{"id":"https://openalex.org/keywords/key","display_name":"Key (lock)","score":0.562747061252594},{"id":"https://openalex.org/keywords/boosting","display_name":"Boosting (machine learning)","score":0.5574910044670105},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4870153069496155},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.46875810623168945},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.41540804505348206},{"id":"https://openalex.org/keywords/computer-security","display_name":"Computer security","score":0.0655314028263092}],"concepts":[{"id":"https://openalex.org/C2779903281","wikidata":"https://www.wikidata.org/wiki/Q6888026","display_name":"Modalities","level":2,"score":0.7614762783050537},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.6805809736251831},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6725335717201233},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6253837943077087},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6103575229644775},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.562747061252594},{"id":"https://openalex.org/C46686674","wikidata":"https://www.wikidata.org/wiki/Q466303","display_name":"Boosting (machine learning)","level":2,"score":0.5574910044670105},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4870153069496155},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.46875810623168945},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.41540804505348206},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0655314028263092},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2018.8513564","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513564","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30441727","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30441727","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1678356000","https://openalex.org/W1880988703","https://openalex.org/W1988494453","https://openalex.org/W1997169200","https://openalex.org/W2002832773","https://openalex.org/W2032655680","https://openalex.org/W2049623605","https://openalex.org/W2057250428","https://openalex.org/W2061497758","https://openalex.org/W2074578935","https://openalex.org/W2100534701","https://openalex.org/W2290432223","https://openalex.org/W2319585903","https://openalex.org/W2322440910","https://openalex.org/W2412188599","https://openalex.org/W2725667553","https://openalex.org/W4240637756","https://openalex.org/W6647724555","https://openalex.org/W6649624150","https://openalex.org/W6658571891","https://openalex.org/W6662886247","https://openalex.org/W6700043664","https://openalex.org/W6822713820"],"related_works":["https://openalex.org/W2125652721","https://openalex.org/W1540371141","https://openalex.org/W4231274751","https://openalex.org/W1549363203","https://openalex.org/W2154063878","https://openalex.org/W2556012038","https://openalex.org/W1489772951","https://openalex.org/W2145188897","https://openalex.org/W4386564352","https://openalex.org/W2952668426"],"abstract_inverted_index":{"The":[0,67,78,98],"detection":[1,25,64],"of":[2,14,52,65,69,96,120],"early":[3],"Parkinson'":[4],"s":[5],"disease":[6],"(PD)":[7],"is":[8,40,75],"crucial":[9],"for":[10,62],"PD":[11,18,24,105],"management.":[12],"Most":[13],"previous":[15],"efforts":[16],"on":[17,22,72,82],"diagnosis":[19,54],"focus":[20],"more":[21,32,45],"improving":[23],"accuracies":[26],"by":[27],"trying":[28],"using":[29],"features":[30,46,70,80,95,115],"from":[31],"modalities,":[33],"which":[34],"results":[35,100],"in":[36],"a":[37,88,103],"common":[38],"question:":[39],"it":[41],"true":[42],"that":[43,102],"the":[44,48,50,53,63],"available,":[47],"better":[49],"performance":[51,107],"system?":[55],"This":[56],"paper":[57],"proposes":[58],"an":[59],"importance-driven":[60],"approach":[61],"PD.":[66,97],"importance":[68,84],"based":[71,81],"gradient":[73],"boosting":[74],"firstly":[76],"learned.":[77],"ranked":[79],"feature":[83],"are":[85,122],"input":[86],"to":[87,92],"progressive":[89],"learning":[90],"pipeline":[91],"find":[93],"key":[94,114],"experiment":[99],"show":[101],"comparable":[104],"classification":[106],"can":[108],"be":[109],"obtained":[110],"with":[111],"much":[112],"less":[113],"and":[116],"therefore":[117],"fewer":[118],"modalities":[119],"tests":[121],"required.":[123],"Such":[124],"findings":[125],"have":[126],"critical":[127],"socioeconomic":[128],"values.":[129]},"counts_by_year":[{"year":2024,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}