{"id":"https://openalex.org/W2899310446","doi":"https://doi.org/10.1109/embc.2018.8513546","title":"Intrinsic Mode Function Complexity Index Using Empirical Mode Decomposition discriminates Normal Sinus Rhythm and Atrial Fibrillation on a Single Lead ECG","display_name":"Intrinsic Mode Function Complexity Index Using Empirical Mode Decomposition discriminates Normal Sinus Rhythm and Atrial Fibrillation on a Single Lead ECG","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2899310446","doi":"https://doi.org/10.1109/embc.2018.8513546","mag":"2899310446","pmid":"https://pubmed.ncbi.nlm.nih.gov/30441701"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513546","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513546","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038203892","display_name":"Suganti Shivaram","orcid":null},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"funder","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I2802423016","display_name":"WinnMed","ror":"https://ror.org/02s47w807","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802423016"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Suganti Shivaram","raw_affiliation_strings":["Mayo Clinic Minnesota, Rochester, MN, US"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic Minnesota, Rochester, MN, US","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I2802423016"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033757760","display_name":"Divaakar Siva Baala Sundaram","orcid":null},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"funder","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I2802423016","display_name":"WinnMed","ror":"https://ror.org/02s47w807","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802423016"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Divaakar Siva Baala Sundaram","raw_affiliation_strings":["Mayo Clinic Minnesota, Rochester, MN, US"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic Minnesota, Rochester, MN, US","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I2802423016"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002899034","display_name":"Rogith Balasubramani","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rogith Balasubramani","raw_affiliation_strings":["Department of Electronics and Communication Engineering, Velalar College of Engineering and Technology, Thindal, Erode, Tamil Nadu, INDIA"],"affiliations":[{"raw_affiliation_string":"Department of Electronics and Communication Engineering, Velalar College of Engineering and Technology, Thindal, Erode, Tamil Nadu, INDIA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024770412","display_name":"Anjani Muthyala","orcid":null},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"funder","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I2802423016","display_name":"WinnMed","ror":"https://ror.org/02s47w807","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802423016"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anjani Muthyala","raw_affiliation_strings":["Mayo Clinic Minnesota, Rochester, MN, US"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic Minnesota, Rochester, MN, US","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I2802423016"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002606430","display_name":"Shivaram P. Arunachalam","orcid":"https://orcid.org/0000-0003-3251-5415"},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"funder","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I2802423016","display_name":"WinnMed","ror":"https://ror.org/02s47w807","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802423016"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shivaram P. Arunachalam","raw_affiliation_strings":["Mayo Clinic Minnesota, Rochester, MN, US"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic Minnesota, Rochester, MN, US","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I2802423016"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5038203892"],"corresponding_institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I2802423016"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23604307,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"45","issue":null,"first_page":"5990","last_page":"5993"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"Atrial fibrillation","score":0.7078876495361328},{"id":"https://openalex.org/keywords/hilbert\u2013huang-transform","display_name":"Hilbert\u2013Huang transform","score":0.7077981233596802},{"id":"https://openalex.org/keywords/sinus-rhythm","display_name":"Sinus rhythm","score":0.6888094544410706},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.6026210188865662},{"id":"https://openalex.org/keywords/normal-sinus-rhythm","display_name":"Normal Sinus Rhythm","score":0.5606391429901123},{"id":"https://openalex.org/keywords/rhythm","display_name":"Rhythm","score":0.5516411662101746},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.5262961387634277},{"id":"https://openalex.org/keywords/mode","display_name":"Mode (computer interface)","score":0.49185824394226074},{"id":"https://openalex.org/keywords/lead","display_name":"Lead (geology)","score":0.47365888953208923},{"id":"https://openalex.org/keywords/electrocardiography","display_name":"Electrocardiography","score":0.4714575409889221},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.42374327778816223},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3543189764022827},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.2888834476470947},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.25565680861473083},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.13874810934066772},{"id":"https://openalex.org/keywords/energy","display_name":"Energy (signal processing)","score":0.08775794506072998},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.08546268939971924}],"concepts":[{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.7078876495361328},{"id":"https://openalex.org/C25570617","wikidata":"https://www.wikidata.org/wiki/Q1006462","display_name":"Hilbert\u2013Huang transform","level":3,"score":0.7077981233596802},{"id":"https://openalex.org/C2775914520","wikidata":"https://www.wikidata.org/wiki/Q12335414","display_name":"Sinus rhythm","level":3,"score":0.6888094544410706},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6026210188865662},{"id":"https://openalex.org/C2908745016","wikidata":"https://www.wikidata.org/wiki/Q12335414","display_name":"Normal Sinus Rhythm","level":3,"score":0.5606391429901123},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.5516411662101746},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5262961387634277},{"id":"https://openalex.org/C48677424","wikidata":"https://www.wikidata.org/wiki/Q6888088","display_name":"Mode (computer interface)","level":2,"score":0.49185824394226074},{"id":"https://openalex.org/C2777093003","wikidata":"https://www.wikidata.org/wiki/Q6508345","display_name":"Lead (geology)","level":2,"score":0.47365888953208923},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.4714575409889221},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.42374327778816223},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3543189764022827},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2888834476470947},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.25565680861473083},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.13874810934066772},{"id":"https://openalex.org/C186370098","wikidata":"https://www.wikidata.org/wiki/Q442787","display_name":"Energy (signal processing)","level":2,"score":0.08775794506072998},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08546268939971924},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2018.8513546","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513546","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30441701","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30441701","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6700000166893005,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W109871117","https://openalex.org/W1978959816","https://openalex.org/W1995121711","https://openalex.org/W2007221293","https://openalex.org/W2013074517","https://openalex.org/W2034377825","https://openalex.org/W2072642281","https://openalex.org/W2079134323","https://openalex.org/W2102566115","https://openalex.org/W2124203956","https://openalex.org/W2124719424","https://openalex.org/W2133771921","https://openalex.org/W2146016003","https://openalex.org/W2147018083","https://openalex.org/W2149092351","https://openalex.org/W2162800060","https://openalex.org/W2415236833","https://openalex.org/W2461375492","https://openalex.org/W2766587342","https://openalex.org/W6678666462"],"related_works":["https://openalex.org/W3024187637","https://openalex.org/W4393997910","https://openalex.org/W1970318676","https://openalex.org/W1994902122","https://openalex.org/W2203497947","https://openalex.org/W2004402067","https://openalex.org/W4238875558","https://openalex.org/W1979741855","https://openalex.org/W2129934160","https://openalex.org/W2971017833"],"abstract_inverted_index":{"Atrial":[0],"fibrillation":[1,209],"(AF)":[2],"is":[3,16,180],"the":[4,74,120,143,190],"most":[5],"common":[6],"sustained":[7],"cardiac":[8,200],"arrhythmia":[9],"affecting":[10],"approximately":[11],"3":[12],"million":[13],"Americans,":[14],"and":[15,24,35,48,58,86,101,123,142,173],"a":[17,183],"prognostic":[18],"marker":[19],"for":[20,63,117,125,132,147,195],"stroke,":[21],"heart":[22],"failure":[23],"even":[25],"death.":[26],"Current":[27],"techniques":[28],"to":[29,72,113],"discriminate":[30],"normal":[31,82,170],"sinus":[32,83,171],"rhythm":[33,84,172],"(NSR)":[34,85],"AF":[36,87,102,150],"from":[37,105],"single":[38,78,166],"lead":[39,79,167],"ECG":[40,53,57,148,168],"suffer":[41],"several":[42],"limitations":[43],"in":[44],"terms":[45],"of":[46,68,76,97,119,177,192,197],"sensitivity":[47],"specificity":[49],"using":[50,88],"short":[51],"time":[52],"data":[54,121,136],"which":[55],"distorts":[56],"many":[59],"are":[60],"not":[61],"suitable":[62],"real-time":[64],"implementation.":[65],"The":[66,128,186],"purpose":[67],"this":[69,178,193],"research":[70],"was":[71,111,138,151],"test":[73],"feasibility":[75],"discriminating":[77],"ECG's":[80,98],"with":[81,99,149,158,169],"intrinsic":[89],"mode":[90],"function":[91],"(IMF)":[92],"complexity":[93,163],"index.":[94],"15":[95,135],"sets":[96,137],"NSR":[100,133],"were":[103],"obtained":[104],"Physionet":[106],"database.":[107],"Custom":[108],"MATLAB\u00ae":[109],"software":[110],"written":[112],"compute":[114],"IMF":[115,130,145,162],"index":[116,131,146],"each":[118],"set":[122],"compared":[124],"statistical":[126,159],"significance.":[127],"mean":[129,144],"across":[134],"0.37":[139],"\u00b1":[140,153],"0.08,":[141],"0.21":[152],"0.07":[154],"showing":[155],"robust":[156],"discrimination":[157],"significance":[160],"(p<0.01).":[161],"robustly":[164],"discriminates":[165],"AF.":[174],"Further":[175],"validation":[176],"result":[179],"required":[181],"on":[182],"larger":[184],"dataset.":[185],"results":[187],"also":[188],"motivate":[189],"use":[191],"technique":[194],"analysis":[196],"other":[198],"complex":[199],"arrhythmias":[201],"such":[202],"as":[203],"ventricular":[204,208],"tachycardia":[205],"(VT)":[206],"or":[207],"(VF).":[210]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}