{"id":"https://openalex.org/W2898785802","doi":"https://doi.org/10.1109/embc.2018.8513515","title":"A Portable Device Integrated with Aligned Carbon Nanotubes for Sensitive Virus Capture and Detection","display_name":"A Portable Device Integrated with Aligned Carbon Nanotubes for Sensitive Virus Capture and Detection","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2898785802","doi":"https://doi.org/10.1109/embc.2018.8513515","mag":"2898785802","pmid":"https://pubmed.ncbi.nlm.nih.gov/30441721"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513515","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513515","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101910886","display_name":"Yin\u2010Ting Yeh","orcid":"https://orcid.org/0000-0002-1512-9267"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yin-Ting Yeh","raw_affiliation_strings":["Pennsylvania State University, University Park, PA, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pennsylvania State University, University Park, PA, US","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036945164","display_name":"Huaguang Lu","orcid":"https://orcid.org/0000-0001-8128-206X"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huaguang Lu","raw_affiliation_strings":["Pennsylvania State University, University Park, PA, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pennsylvania State University, University Park, PA, US","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086903169","display_name":"Siyang Zheng","orcid":"https://orcid.org/0000-0002-0616-030X"},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Si-Yang Zheng","raw_affiliation_strings":["Pennsylvania State University, University Park, PA, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pennsylvania State University, University Park, PA, US","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041297453","display_name":"and Mauricio Terrones","orcid":null},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"and Mauricio Terrones","raw_affiliation_strings":["Pennsylvania State University, University Park, PA, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pennsylvania State University, University Park, PA, US","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":null,"first_page":"6072","last_page":"6075"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbon-nanotube","display_name":"Carbon nanotube","score":0.7744059562683105},{"id":"https://openalex.org/keywords/polydimethylsiloxane","display_name":"Polydimethylsiloxane","score":0.7189762592315674},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.7107571363449097},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.6304683089256287},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.6063407063484192},{"id":"https://openalex.org/keywords/chemical-vapor-deposition","display_name":"Chemical vapor deposition","score":0.5370779037475586},{"id":"https://openalex.org/keywords/porosity","display_name":"Porosity","score":0.4364088177680969},{"id":"https://openalex.org/keywords/cartridge","display_name":"Cartridge","score":0.4224567115306854},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.20550352334976196}],"concepts":[{"id":"https://openalex.org/C513720949","wikidata":"https://www.wikidata.org/wiki/Q1778729","display_name":"Carbon nanotube","level":2,"score":0.7744059562683105},{"id":"https://openalex.org/C2779849746","wikidata":"https://www.wikidata.org/wiki/Q411955","display_name":"Polydimethylsiloxane","level":2,"score":0.7189762592315674},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7107571363449097},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6304683089256287},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.6063407063484192},{"id":"https://openalex.org/C57410435","wikidata":"https://www.wikidata.org/wiki/Q505668","display_name":"Chemical vapor deposition","level":2,"score":0.5370779037475586},{"id":"https://openalex.org/C6648577","wikidata":"https://www.wikidata.org/wiki/Q622669","display_name":"Porosity","level":2,"score":0.4364088177680969},{"id":"https://openalex.org/C34381374","wikidata":"https://www.wikidata.org/wiki/Q37144","display_name":"Cartridge","level":2,"score":0.4224567115306854},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.20550352334976196},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005740","descriptor_name":"Gases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005740","descriptor_name":"Gases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005740","descriptor_name":"Gases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014780","descriptor_name":"Viruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016062","descriptor_name":"Porosity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016062","descriptor_name":"Porosity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016062","descriptor_name":"Porosity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037742","descriptor_name":"Nanotubes, Carbon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D037742","descriptor_name":"Nanotubes, Carbon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D037742","descriptor_name":"Nanotubes, Carbon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2018.8513515","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513515","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30441721","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30441721","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320308615","display_name":"Thrasher Research Fund","ror":"https://ror.org/03hnrwx04"},{"id":"https://openalex.org/F4320310419","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W263651485","https://openalex.org/W627426938","https://openalex.org/W1597037822","https://openalex.org/W1982554116","https://openalex.org/W1984454650","https://openalex.org/W2055181644","https://openalex.org/W2075741684","https://openalex.org/W2100187217","https://openalex.org/W2102216674","https://openalex.org/W2320818167","https://openalex.org/W4286853110","https://openalex.org/W6817476913"],"related_works":["https://openalex.org/W2033967534","https://openalex.org/W1535546264","https://openalex.org/W2784354338","https://openalex.org/W2358103399","https://openalex.org/W2367349075","https://openalex.org/W16040430","https://openalex.org/W2032120680","https://openalex.org/W2041649610","https://openalex.org/W2317708157","https://openalex.org/W2087078781"],"abstract_inverted_index":{"Point-of-care":[0],"virus":[1,44,88],"diagnosis":[2],"is":[3,49,110],"highly":[4],"desirable":[5],"in":[6,126],"worldwide":[7],"infectious":[8,138],"disease":[9],"control.":[10],"Here":[11],"we":[12],"report":[13],"a":[14,27,52,77],"hand-held":[15],"device":[16,29,48,109],"for":[17],"capturing":[18],"viruses":[19],"by":[20,135],"applying":[21],"physical":[22],"size":[23,70],"based":[24],"exclusion":[25],"inside":[26],"point-of-care":[28],"integrated":[30],"with":[31,76,129],"vertically":[32],"aligned":[33],"carbon":[34],"nanotube":[35],"(VACNT)":[36],"nanostructures":[37],"to":[38],"achieve":[39],"label-free":[40],"and":[41,71],"high":[42],"throughput":[43],"capture.":[45],"The":[46,63],"microfluidic":[47],"constructed":[50],"from":[51],"VACNT":[53,64,93],"channel":[54,94],"wall":[55,95],"synthesized":[56],"bottom-up":[57],"via":[58],"chemical":[59],"vapor":[60],"deposition":[61],"(CVD).":[62],"has":[65],"~117":[66],"nm":[67],"average":[68],"gap":[69],"~97&":[72],"porosity.":[73],"By":[74],"bonding":[75],"polydimethylsiloxane":[78],"(PDMS)":[79],"cover":[80],"sealing":[81],"the":[82,84,92,101,108,136],"top,":[83],"aqueous":[85],"sample":[86],"containing":[87,118],"particles":[89,125],"filter":[90],"through":[91],"under":[96],"negative":[97],"pressure":[98],"applied":[99],"at":[100],"outlet":[102],"end.":[103],"We":[104],"have":[105],"demonstrated":[106],"that":[107],"capable":[111],"of":[112,116,123,131],"filtering":[113],"50":[114],"\u03bcL":[115],"PBS":[117],"~6.3":[119],"\u00d7":[120],"104":[121],"counts":[122],"lentivirus":[124],"10":[127],"minutes":[128],"97&":[130],"capture":[132],"efficiency,":[133],"quantified":[134],"cell":[137],"titration":[139],"technique.":[140]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}