{"id":"https://openalex.org/W2899253738","doi":"https://doi.org/10.1109/embc.2018.8513129","title":"Isometry Invariant Shape Descriptors for Abnormality Detection on Brain Surfaces Affected by Alzheimer\u2019s Disease","display_name":"Isometry Invariant Shape Descriptors for Abnormality Detection on Brain Surfaces Affected by Alzheimer\u2019s Disease","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2899253738","doi":"https://doi.org/10.1109/embc.2018.8513129","mag":"2899253738","pmid":"https://pubmed.ncbi.nlm.nih.gov/30440425"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513129","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513129","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016165239","display_name":"Yanshuai Tu","orcid":"https://orcid.org/0000-0002-4619-2613"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yanshuai Tu","raw_affiliation_strings":["Arizona State University, Tempe, AZ, US"],"affiliations":[{"raw_affiliation_string":"Arizona State University, Tempe, AZ, US","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085386237","display_name":"Chengfeng Wen","orcid":"https://orcid.org/0000-0001-7183-430X"},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chengfeng Wen","raw_affiliation_strings":["Stony Brook University, Stony Brook, NY, US"],"affiliations":[{"raw_affiliation_string":"Stony Brook University, Stony Brook, NY, US","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100444409","display_name":"Wen Zhang","orcid":"https://orcid.org/0000-0002-8934-3346"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen Zhang","raw_affiliation_strings":["Arizona State University, Tempe, AZ, US"],"affiliations":[{"raw_affiliation_string":"Arizona State University, Tempe, AZ, US","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101826689","display_name":"Jianfeng Wu","orcid":"https://orcid.org/0000-0003-3990-5897"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianfeng Wu","raw_affiliation_strings":["Arizona State University, Tempe, AZ, US"],"affiliations":[{"raw_affiliation_string":"Arizona State University, Tempe, AZ, US","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100436906","display_name":"Jie Zhang","orcid":"https://orcid.org/0009-0002-6551-5921"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jie Zhang","raw_affiliation_strings":["Arizona State University, Tempe, AZ, US"],"affiliations":[{"raw_affiliation_string":"Arizona State University, Tempe, AZ, US","institution_ids":["https://openalex.org/I55732556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100325379","display_name":"Kewei Chen","orcid":"https://orcid.org/0000-0001-8497-3069"},"institutions":[{"id":"https://openalex.org/I4387152203","display_name":"Banner Alzheimer\u2019s Institute","ror":"https://ror.org/023jwkg52","country_code":null,"type":"facility","lineage":["https://openalex.org/I2802412784","https://openalex.org/I4387152203"]},{"id":"https://openalex.org/I2802412784","display_name":"Banner Health","ror":"https://ror.org/039wwwz66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802412784"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kewei Chen","raw_affiliation_strings":["Banner Alzheimers Institute, Phoenix, AZ"],"affiliations":[{"raw_affiliation_string":"Banner Alzheimers Institute, Phoenix, AZ","institution_ids":["https://openalex.org/I2802412784","https://openalex.org/I4387152203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107846134","display_name":"Richard J. Caselli","orcid":null},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I2801572250","display_name":"Jacksonville College","ror":"https://ror.org/03a9t7g49","country_code":"US","type":"education","lineage":["https://openalex.org/I2801572250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard J. Caselli","raw_affiliation_strings":["Mayo Clinic's Campus in Florida, Jacksonville, FL, US"],"affiliations":[{"raw_affiliation_string":"Mayo Clinic's Campus in Florida, Jacksonville, FL, US","institution_ids":["https://openalex.org/I2801572250","https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047768726","display_name":"Eric M. Reiman","orcid":"https://orcid.org/0000-0002-0705-3696"},"institutions":[{"id":"https://openalex.org/I4387152203","display_name":"Banner Alzheimer\u2019s Institute","ror":"https://ror.org/023jwkg52","country_code":null,"type":"facility","lineage":["https://openalex.org/I2802412784","https://openalex.org/I4387152203"]},{"id":"https://openalex.org/I2802412784","display_name":"Banner Health","ror":"https://ror.org/039wwwz66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802412784"]},{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric M. Reiman","raw_affiliation_strings":["Banner Alzheimers Institute, Phoenix, AZ","Stony Brook University, Stony Brook, NY, US"],"affiliations":[{"raw_affiliation_string":"Banner Alzheimers Institute, Phoenix, AZ","institution_ids":["https://openalex.org/I2802412784","https://openalex.org/I4387152203"]},{"raw_affiliation_string":"Stony Brook University, Stony Brook, NY, US","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047768726","display_name":"Eric M. Reiman","orcid":"https://orcid.org/0000-0002-0705-3696"},"institutions":[{"id":"https://openalex.org/I59553526","display_name":"Stony Brook University","ror":"https://ror.org/05qghxh33","country_code":"US","type":"education","lineage":["https://openalex.org/I59553526"]},{"id":"https://openalex.org/I2802412784","display_name":"Banner Health","ror":"https://ror.org/039wwwz66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802412784"]},{"id":"https://openalex.org/I4387152203","display_name":"Banner Alzheimer\u2019s Institute","ror":"https://ror.org/023jwkg52","country_code":null,"type":"facility","lineage":["https://openalex.org/I2802412784","https://openalex.org/I4387152203"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric M. Reiman","raw_affiliation_strings":["Banner Alzheimers Institute, Phoenix, AZ","Stony Brook University, Stony Brook, NY, US"],"affiliations":[{"raw_affiliation_string":"Banner Alzheimers Institute, Phoenix, AZ","institution_ids":["https://openalex.org/I2802412784","https://openalex.org/I4387152203"]},{"raw_affiliation_string":"Stony Brook University, Stony Brook, NY, US","institution_ids":["https://openalex.org/I59553526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100740828","display_name":"Yalin Wang","orcid":"https://orcid.org/0000-0002-6241-735X"},"institutions":[{"id":"https://openalex.org/I55732556","display_name":"Arizona State University","ror":"https://ror.org/03efmqc40","country_code":"US","type":"education","lineage":["https://openalex.org/I55732556"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yalin Wang","raw_affiliation_strings":["Arizona State University, Tempe, AZ, US"],"affiliations":[{"raw_affiliation_string":"Arizona State University, Tempe, AZ, US","institution_ids":["https://openalex.org/I55732556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5016165239"],"corresponding_institution_ids":["https://openalex.org/I55732556"],"apc_list":null,"apc_paid":null,"fwci":0.1605,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.55442773,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"21","issue":null,"first_page":"427","last_page":"4631"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9814000129699707,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6394082307815552},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6166515946388245},{"id":"https://openalex.org/keywords/dementia","display_name":"Dementia","score":0.5794129371643066},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.5778392553329468},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.5057988166809082},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.48864370584487915},{"id":"https://openalex.org/keywords/isometry","display_name":"Isometry (Riemannian geometry)","score":0.46696025133132935},{"id":"https://openalex.org/keywords/gyrification","display_name":"Gyrification","score":0.4459027349948883},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.4454713463783264},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3659776449203491},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3044658303260803},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.28037965297698975},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.27557194232940674},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2660380005836487},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.22392615675926208},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.10794186592102051}],"concepts":[{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6394082307815552},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6166515946388245},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.5794129371643066},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.5778392553329468},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5057988166809082},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.48864370584487915},{"id":"https://openalex.org/C82457910","wikidata":"https://www.wikidata.org/wiki/Q740207","display_name":"Isometry (Riemannian geometry)","level":2,"score":0.46696025133132935},{"id":"https://openalex.org/C2780914113","wikidata":"https://www.wikidata.org/wiki/Q19468049","display_name":"Gyrification","level":3,"score":0.4459027349948883},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.4454713463783264},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3659776449203491},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3044658303260803},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.28037965297698975},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.27557194232940674},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2660380005836487},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.22392615675926208},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.10794186592102051},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060388","descriptor_name":"Support Vector Machine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2018.8513129","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513129","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30440425","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30440425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:europepmc.org:5204012","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6241283","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.7300000190734863}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1746965720","https://openalex.org/W1967068826","https://openalex.org/W1973142739","https://openalex.org/W1974797012","https://openalex.org/W1987909254","https://openalex.org/W1998710995","https://openalex.org/W2024849762","https://openalex.org/W2038003677","https://openalex.org/W2041398617","https://openalex.org/W2071681524","https://openalex.org/W2088851552","https://openalex.org/W2100657858","https://openalex.org/W2100792560","https://openalex.org/W2113319997","https://openalex.org/W2127033124","https://openalex.org/W2128480875","https://openalex.org/W2129497119","https://openalex.org/W2158514158","https://openalex.org/W2489625196","https://openalex.org/W2508153689","https://openalex.org/W2526850289","https://openalex.org/W2558927549","https://openalex.org/W2619410643","https://openalex.org/W2716233262","https://openalex.org/W2752287204","https://openalex.org/W2962929605","https://openalex.org/W4297757641","https://openalex.org/W6650119846","https://openalex.org/W6727793272","https://openalex.org/W6729613352"],"related_works":["https://openalex.org/W2025453479","https://openalex.org/W4388417611","https://openalex.org/W2444574782","https://openalex.org/W2088198702","https://openalex.org/W2038213387","https://openalex.org/W2105113370","https://openalex.org/W3037836458","https://openalex.org/W2150970214","https://openalex.org/W2048029629","https://openalex.org/W2074243908"],"abstract_inverted_index":{"Alzheimer's":[0],"disease":[1,12],"(AD),":[2],"a":[3,18,60,66,83,96,152,164,238],"progressive":[4],"brain":[5,21,42,90,208],"disorder,":[6],"is":[7,17,69,116,170,197,218],"the":[8,53,104,109,111,179,201],"most":[9],"common":[10],"neurodegenerative":[11],"in":[13,71,74,78,220],"older":[14],"adults.":[15],"There":[16],"need":[19],"for":[20,89,159],"structural":[22],"magnetic":[23],"resonance":[24],"imaging":[25,43,147],"(MRI)":[26],"biomarkers":[27],"to":[28,63,103,172,224,243],"help":[29],"assess":[30],"AD":[31,50,134,146,225],"progression":[32],"and":[33,76,240,247],"intervention":[34],"effects.":[35],"Prior":[36],"research":[37],"showed":[38],"that":[39,68,125,214],"surface":[40,102,209,246],"based":[41],"features":[44,128],"hold":[45],"great":[46],"promise":[47],"as":[48,143],"efficient":[49],"biomarkers.":[51],"However,":[52],"complex":[54],"geometry":[55],"of":[56,120,182],"cortical":[57,101,245],"surfaces":[58],"poses":[59],"major":[61],"challenge":[62],"defining":[64],"such":[65],"feature":[67,160],"sensitive":[70],"qualification,":[72],"robust":[73],"analysis,":[75],"intuitive":[77,241],"visualization.":[79],"Here":[80],"we":[81,94],"propose":[82],"novel":[84,153],"isometry":[85,232],"invariant":[86,233],"shape":[87,114,122,216,234],"descriptor":[88,115,217],"morphometry":[91,249],"analysis.":[92],"First,":[93],"calculate":[95],"global":[97],"area-preserving":[98],"mapping":[99],"from":[100,187,226],"unit":[105],"sphere.":[106],"Based":[107],"on":[108,200],"mapping,":[110],"Beltrami":[112],"coefficient":[113],"calculated.":[117],"An":[118],"analysis":[119],"average":[121],"descriptors":[123,235],"reveals":[124],"our":[126,215],"detected":[127],"are":[129],"consistent":[130],"with":[131,178],"some":[132,204],"previous":[133],"studies":[135],"where":[136],"medial":[137],"temporal":[138],"lobe":[139],"volume":[140],"was":[141],"identified":[142],"an":[144],"important":[145],"biomarker.":[148],"We":[149],"further":[150],"apply":[151],"patch-based":[154],"spherical":[155],"sparse":[156],"coding":[157],"scheme":[158],"dimension":[161],"reduction.":[162],"Later,":[163],"support":[165],"vector":[166],"machine":[167],"(SVM)":[168],"classifier":[169],"applied":[171],"discriminate":[173],"135":[174],"amyloid-beta":[175],"positive":[176],"persons":[177],"clinical":[180],"diagnosis":[181],"Mild":[183],"Cognitive":[184],"Impairment":[185],"(MCI)":[186],"248":[188],"amyloid-beta-negative":[189],"normal":[190,228],"control":[191],"subjects.":[192],"The":[193,211],"5-folder":[194],"cross-validation":[195],"accuracy":[196],"about":[198],"81.82\\%":[199],"dataset,":[202],"outperforming":[203],"traditional,":[205],"Freesurfer":[206],"based,":[207],"features.":[210],"results":[212],"show":[213],"effective":[219],"distinguishing":[221],"dementia":[222],"due":[223],"age-matched":[227],"aging":[229],"individuals.":[230],"Our":[231],"may":[236],"provide":[237],"unique":[239],"way":[242],"inspect":[244],"its":[248],"changes.":[250]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}