{"id":"https://openalex.org/W2898808929","doi":"https://doi.org/10.1109/embc.2018.8513127","title":"Validating an Algorithm for Automatic Scoring of Inspiratory Flow Limitation Within a Range of Recording Settings","display_name":"Validating an Algorithm for Automatic Scoring of Inspiratory Flow Limitation Within a Range of Recording Settings","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2898808929","doi":"https://doi.org/10.1109/embc.2018.8513127","mag":"2898808929","pmid":"https://pubmed.ncbi.nlm.nih.gov/30441417"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513127","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513127","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052207319","display_name":"Alessandra Camassa","orcid":"https://orcid.org/0000-0002-5010-7055"},"institutions":[{"id":"https://openalex.org/I4210160192","display_name":"Consorci Institut D'Investigacions Biomediques August Pi I Sunyer","ror":"https://ror.org/054vayn55","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210160192","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Alessandra Camassa","raw_affiliation_strings":["Institut d\u2019Investigacions Biom\u00e8diques August Pi Sunyer (IDIBAPS), Barcelona, Spain","Institut d'Investigacions Biom\u00e8diques August Pi Sunyer (IDIBAPS), Barcelona, Spain"],"affiliations":[{"raw_affiliation_string":"Institut d\u2019Investigacions Biom\u00e8diques August Pi Sunyer (IDIBAPS), Barcelona, Spain","institution_ids":["https://openalex.org/I4210160192"]},{"raw_affiliation_string":"Institut d'Investigacions Biom\u00e8diques August Pi Sunyer (IDIBAPS), Barcelona, Spain","institution_ids":["https://openalex.org/I4210160192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075738097","display_name":"Angelo Franciosini","orcid":"https://orcid.org/0000-0003-1468-0046"},"institutions":[{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Angelo Franciosini","raw_affiliation_strings":["Aix-Marseille Universite, Marseille, Provence-Alpes-C\u00c3\u00b4te d'Azu, FR","Aix-Marseille Universite, Marseille, Provence-Alpes-C\u00f4te d'Azu, FR"],"affiliations":[{"raw_affiliation_string":"Aix-Marseille Universite, Marseille, Provence-Alpes-C\u00c3\u00b4te d'Azu, FR","institution_ids":["https://openalex.org/I21491767"]},{"raw_affiliation_string":"Aix-Marseille Universite, Marseille, Provence-Alpes-C\u00f4te d'Azu, FR","institution_ids":["https://openalex.org/I21491767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044771428","display_name":"Scott A. Sands","orcid":"https://orcid.org/0000-0003-3752-0328"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott A. Sands","raw_affiliation_strings":["Harvard Medical School, Boston, MA, US"],"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, US","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056393066","display_name":"Ying Xuan Zhi","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ying Xuan Zhi","raw_affiliation_strings":["University of Toronto, Toronto, ON, CA"],"affiliations":[{"raw_affiliation_string":"University of Toronto, Toronto, ON, CA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038736970","display_name":"Azadeh Yadollahi","orcid":"https://orcid.org/0000-0002-3216-8997"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Azadeh Yadollahi","raw_affiliation_strings":["University of Toronto, Toronto, ON, CA"],"affiliations":[{"raw_affiliation_string":"University of Toronto, Toronto, ON, CA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073440301","display_name":"Anna Maria Bianchi","orcid":"https://orcid.org/0000-0002-8290-7460"},"institutions":[{"id":"https://openalex.org/I93860229","display_name":"Politecnico di Milano","ror":"https://ror.org/01nffqt88","country_code":"IT","type":"education","lineage":["https://openalex.org/I93860229"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Anna M. Bianchi","raw_affiliation_strings":["Politecnico di Milano, Milano, Lombardia, IT"],"affiliations":[{"raw_affiliation_string":"Politecnico di Milano, Milano, Lombardia, IT","institution_ids":["https://openalex.org/I93860229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073753709","display_name":"Andrew Wellman","orcid":"https://orcid.org/0000-0002-9000-3007"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Wellman","raw_affiliation_strings":["Harvard Medical School, Boston, MA, US"],"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, US","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050330450","display_name":"Susan Redline","orcid":"https://orcid.org/0000-0002-6585-1610"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan Redline","raw_affiliation_strings":["Harvard Medical School, Boston, MA, US"],"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, US","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079420954","display_name":"Ali Azarbarzin","orcid":"https://orcid.org/0000-0002-4986-4753"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ali Azarbarzin","raw_affiliation_strings":["Harvard Medical School, Boston, MA, US"],"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, US","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080092220","display_name":"Sara Mariani","orcid":"https://orcid.org/0000-0003-3761-3612"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sara Mariani","raw_affiliation_strings":["Harvard Medical School, Boston, MA, US"],"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA, US","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5052207319"],"corresponding_institution_ids":["https://openalex.org/I4210160192"],"apc_list":null,"apc_paid":null,"fwci":0.4066,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.6404632,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"2018","issue":null,"first_page":"4788","last_page":"4791"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9864000082015991,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6219519972801208},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.5460439324378967},{"id":"https://openalex.org/keywords/polysomnography","display_name":"Polysomnography","score":0.5404082536697388},{"id":"https://openalex.org/keywords/gold-standard","display_name":"Gold standard (test)","score":0.42174533009529114},{"id":"https://openalex.org/keywords/speech-recognition","display_name":"Speech recognition","score":0.4037211239337921},{"id":"https://openalex.org/keywords/apnea","display_name":"Apnea","score":0.3981534540653229},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3704718351364136},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.36004090309143066},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.34735724329948425},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.1101635992527008},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.10292685031890869}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6219519972801208},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.5460439324378967},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.5404082536697388},{"id":"https://openalex.org/C40993552","wikidata":"https://www.wikidata.org/wiki/Q514654","display_name":"Gold standard (test)","level":2,"score":0.42174533009529114},{"id":"https://openalex.org/C28490314","wikidata":"https://www.wikidata.org/wiki/Q189436","display_name":"Speech recognition","level":1,"score":0.4037211239337921},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.3981534540653229},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3704718351364136},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36004090309143066},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.34735724329948425},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1101635992527008},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.10292685031890869}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001331","descriptor_name":"Automation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001331","descriptor_name":"Automation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001331","descriptor_name":"Automation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009666","descriptor_name":"Nose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009666","descriptor_name":"Nose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009666","descriptor_name":"Nose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011996","descriptor_name":"Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011996","descriptor_name":"Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011996","descriptor_name":"Records","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012891","descriptor_name":"Sleep Apnea Syndromes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017286","descriptor_name":"Polysomnography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2018.8513127","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513127","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30441417","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30441417","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:re.public.polimi.it:11311/1079999","is_oa":false,"landing_page_url":"http://hdl.handle.net/11311/1079999","pdf_url":null,"source":{"id":"https://openalex.org/S4306400312","display_name":"Virtual Community of Pathological Anatomy (University of Castilla La Mancha)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I79189158","host_organization_name":"University of Castilla-La Mancha","host_organization_lineage":["https://openalex.org/I79189158"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W149332737","https://openalex.org/W2088828197","https://openalex.org/W2095543013","https://openalex.org/W2125339588","https://openalex.org/W2128189145","https://openalex.org/W2201213898","https://openalex.org/W2599803799","https://openalex.org/W2728748020","https://openalex.org/W2754810003","https://openalex.org/W2788947442","https://openalex.org/W6740666790"],"related_works":["https://openalex.org/W2149145101","https://openalex.org/W2376105158","https://openalex.org/W2508346598","https://openalex.org/W2980868362","https://openalex.org/W62530852","https://openalex.org/W4367186133","https://openalex.org/W4294175711","https://openalex.org/W1969068200","https://openalex.org/W4388950428","https://openalex.org/W2037309944"],"abstract_inverted_index":{"Inspiratory":[0],"Flow":[1],"Limitation":[2],"(IFL)":[3],"is":[4,97],"a":[5,175,287],"phenomenon":[6],"associated":[7],"with":[8,217,271],"narrowing":[9],"of":[10,32,61,65,80,103,110,122,159,165,191,202,260],"the":[11,43,101,104,108,111,145,149,160,166,189,203,210,265,282],"upper":[12],"airway,":[13],"preventing":[14],"an":[15,21],"increase":[16],"in":[17,23,47,126],"inspiratory":[18],"airflow":[19],"despite":[20],"elevation":[22],"intrathoracic":[24],"pressure.":[25],"It":[26],"has":[27,63],"been":[28,64],"shown":[29],"that":[30,281],"quantification":[31],"IFL":[33,62,139,182],"might":[34],"complement":[35],"information":[36],"provided":[37],"by":[38],"standard":[39],"indices":[40],"such":[41],"as":[42,85,120,138,148],"apnea-hypopnea":[44],"index":[45],"(AHI)":[46],"characterizing":[48],"sleep":[49],"disordered":[50],"breathing":[51],"and":[52,68,77,88,94,142,162,168,173,195,220,241,289],"identifying":[53],"subclinical":[54],"disease.":[55],"Defining":[56],"guidelines":[57],"for":[58,209,222,237,242,256,292],"visual":[59],"scoring":[60,147],"increasing":[66,223],"interest,":[67],"automated":[69,112],"methods":[70],"are":[71],"desirable":[72],"to":[73,99,171,180,235,254],"avoid":[74],"inter-scorer":[75],"variability":[76],"allow":[78],"analysis":[79],"large":[81],"datasets.":[82],"In":[83],"addition,":[84],"recording":[86,105],"instrumentation":[87],"practices":[89],"may":[90],"vary":[91],"across":[92],"hospitals":[93],"laboratories,":[95],"it":[96],"useful":[98],"assess":[100],"influence":[102],"parameters":[106],"on":[107,197],"accuracy":[109],"classification.":[113,294],"We":[114,186,278],"employed":[115],"nasal":[116],"pressure":[117],"signals":[118,167,212],"recorded":[119],"part":[121],"polysomnography":[123],"(PSG)":[124],"studies":[125],"7":[127],"patients.":[128],"Two":[129],"experts":[130],"independently":[131],"classified":[132],"approximately":[133],"2000":[134],"breaths":[135],"per":[136],"subject":[137],"or":[140],"non-IFL,":[141],"we":[143,155],"used":[144,169],"consensus":[146],"gold":[150],"standard.":[151],"For":[152],"each":[153],"breath,":[154],"derived":[156],"features":[157],"indicative":[158],"shape":[161],"frequency":[163],"content":[164],"them":[170],"train":[172],"validate":[174],"Support":[176],"Vector":[177],"Machine":[178],"(SVM)":[179],"distinguish":[181],"from":[183],"non-IFL":[184],"breaths.":[185],"also":[187],"assessed":[188],"effect":[190],"signal":[192],"filtering":[193,273],"(down-sampling":[194],"baseline-removal)":[196],"classification":[198],"performance.":[199],"The":[200],"performance":[201,261],"classifier":[204,266],"was":[205,262,267],"excellent":[206],"(accuracy":[207,275],"~93%)":[208],"raw":[211],"(collected":[213],"at":[214],"125":[215],"Hz":[216,240],"no":[218],"filtering),":[219],"decreased":[221],"high-pass":[224],"cut-off":[225],"frequencies":[226],"(fc":[227],"=":[228,247],"[0.05,":[229],"0.1,":[230],"0.15,":[231],"0.2]":[232],"Hz)":[233,252],"down":[234,253],"84%":[236],"fc=":[238],"0.2":[239],"decreasing":[243],"sampling":[244],"rate":[245],"(fs":[246],"[20,":[248],"50,":[249],"75,":[250],"100]":[251],"~85%":[255],"fs=20":[257],"Hz.":[258],"Loss":[259],"minimized":[263],"when":[264],"re-trained":[268],"using":[269],"data":[270],"matched":[272],"characteristics":[274],">":[276],"89%).":[277],"can":[279],"conclude":[280],"SVM":[283],"feature-based":[284],"algorithm":[285],"provides":[286],"reliable":[288],"efficient":[290],"tool":[291],"breath-by-breath":[293]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}