{"id":"https://openalex.org/W2898795851","doi":"https://doi.org/10.1109/embc.2018.8513110","title":"In Vivo Hemodynamic Evaluation of CH-VAD in a Bovine Model for 14 Days","display_name":"In Vivo Hemodynamic Evaluation of CH-VAD in a Bovine Model for 14 Days","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2898795851","doi":"https://doi.org/10.1109/embc.2018.8513110","mag":"2898795851","pmid":"https://pubmed.ncbi.nlm.nih.gov/30441354"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513110","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513110","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100404360","display_name":"Yaxin Wang","orcid":"https://orcid.org/0000-0003-1903-1037"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yaxin Wang","raw_affiliation_strings":["Texas Heart Institute, Houston, TX, US"],"affiliations":[{"raw_affiliation_string":"Texas Heart Institute, Houston, TX, US","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111865477","display_name":"Jeff L. Conger","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeff L. Conger","raw_affiliation_strings":["Texas Heart Institute, Houston, TX, US"],"affiliations":[{"raw_affiliation_string":"Texas Heart Institute, Houston, TX, US","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054838067","display_name":"Kelly M. Handy","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kelly Handy","raw_affiliation_strings":["Texas Heart Institute, Houston, TX, US"],"affiliations":[{"raw_affiliation_string":"Texas Heart Institute, Houston, TX, US","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101681627","display_name":"P. Alex Smith","orcid":"https://orcid.org/0000-0002-0560-6568"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. Alex Smith","raw_affiliation_strings":["Texas Heart Institute, Houston, TX, US"],"affiliations":[{"raw_affiliation_string":"Texas Heart Institute, Houston, TX, US","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017994911","display_name":"Faisal H. Cheema","orcid":"https://orcid.org/0000-0003-0441-8028"},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Faisal H. Cheema","raw_affiliation_strings":["Baylor College of Medicine and the Texas Heart Institute, Houston, TX, 77030, USA"],"affiliations":[{"raw_affiliation_string":"Baylor College of Medicine and the Texas Heart Institute, Houston, TX, 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102796439","display_name":"Luiz C. Sampaio","orcid":"https://orcid.org/0000-0002-5226-0707"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luiz C. Sampaio","raw_affiliation_strings":["Texas Heart Institute, Houston, TX, US"],"affiliations":[{"raw_affiliation_string":"Texas Heart Institute, Houston, TX, US","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019219753","display_name":"Frank Lin","orcid":null},"institutions":[{"id":"https://openalex.org/I177607063","display_name":"The Lundquist Institute","ror":"https://ror.org/025j2nd68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I177607063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank Lin","raw_affiliation_strings":["CH Biomedical (USA), Inc., Torrance, CA, USA"],"affiliations":[{"raw_affiliation_string":"CH Biomedical (USA), Inc., Torrance, CA, USA","institution_ids":["https://openalex.org/I177607063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100418548","display_name":"Chen Chen","orcid":"https://orcid.org/0000-0003-2104-534X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chen Chen","raw_affiliation_strings":["CH Biomedical, Inc., Suzhou, China"],"affiliations":[{"raw_affiliation_string":"CH Biomedical, Inc., Suzhou, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042802176","display_name":"Jeffrey A. Morgan","orcid":"https://orcid.org/0009-0006-6476-161X"},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey A. Morgan","raw_affiliation_strings":["Baylor College of Medicine and the Texas Heart Institute, Houston, TX, 77030, USA"],"affiliations":[{"raw_affiliation_string":"Baylor College of Medicine and the Texas Heart Institute, Houston, TX, 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5100404360"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.109,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.4584288,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"40","issue":null,"first_page":"4512","last_page":"4515"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12598","display_name":"Cardiac Structural Anomalies and Repair","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemodynamics","display_name":"Hemodynamics","score":0.8172149658203125},{"id":"https://openalex.org/keywords/ventricular-assist-device","display_name":"Ventricular assist device","score":0.6826987266540527},{"id":"https://openalex.org/keywords/thrombus","display_name":"Thrombus","score":0.605960488319397},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6036306619644165},{"id":"https://openalex.org/keywords/ventricle","display_name":"Ventricle","score":0.5731728672981262},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.49425387382507324},{"id":"https://openalex.org/keywords/descending-aorta","display_name":"Descending aorta","score":0.4339953064918518},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.37267130613327026},{"id":"https://openalex.org/keywords/aorta","display_name":"Aorta","score":0.371635377407074},{"id":"https://openalex.org/keywords/heart-failure","display_name":"Heart failure","score":0.3384411036968231},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.33324718475341797}],"concepts":[{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.8172149658203125},{"id":"https://openalex.org/C2778774980","wikidata":"https://www.wikidata.org/wiki/Q2897721","display_name":"Ventricular assist device","level":3,"score":0.6826987266540527},{"id":"https://openalex.org/C2781362458","wikidata":"https://www.wikidata.org/wiki/Q1588755","display_name":"Thrombus","level":2,"score":0.605960488319397},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6036306619644165},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.5731728672981262},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.49425387382507324},{"id":"https://openalex.org/C2780663194","wikidata":"https://www.wikidata.org/wiki/Q3270170","display_name":"Descending aorta","level":3,"score":0.4339953064918518},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37267130613327026},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.371635377407074},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.3384411036968231},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.33324718475341797}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006353","descriptor_name":"Heart-Assist Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006353","descriptor_name":"Heart-Assist Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006353","descriptor_name":"Heart-Assist Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2018.8513110","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513110","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30441354","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30441354","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6499999761581421,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W26524032","https://openalex.org/W2015704812","https://openalex.org/W2039545031","https://openalex.org/W2042027726","https://openalex.org/W2103149583","https://openalex.org/W2106641986","https://openalex.org/W2147601327","https://openalex.org/W2421270776","https://openalex.org/W2580792129","https://openalex.org/W4385437251"],"related_works":["https://openalex.org/W2415845174","https://openalex.org/W2093232606","https://openalex.org/W2413481960","https://openalex.org/W2022154546","https://openalex.org/W3043270608","https://openalex.org/W2329191057","https://openalex.org/W2325618378","https://openalex.org/W2085104584","https://openalex.org/W2182910414","https://openalex.org/W2396152760"],"abstract_inverted_index":{"The":[0,100,115],"CH-VAD":[1,54,85,120,179],"is":[2,20,29,42],"a":[3,56,68,87,97],"centrifugal-flow":[4],"magnetically":[5],"levitated":[6],"(maglev)":[7],"left":[8,36],"ventricular":[9],"assist":[10],"device":[11],"(LVAD)":[12],"used":[13],"to":[14,44],"treat":[15],"end-stage":[16],"heart":[17],"failure.":[18],"It":[19],"implanted":[21,83],"in":[22,75,86],"the":[23,26,32,35,39,45,53,84,91,103,113,119,130,141,150,154,157,163,167,178,191],"chest":[24],"cavity;":[25],"inflow":[27,192],"cannula":[28],"inserted":[30],"into":[31],"apex":[33],"of":[34,77,135,171,177,185],"ventricle,":[37],"and":[38,63,89,93,106,132,156,161,166],"outflow":[40,194],"graft":[41],"anastomosed":[43],"aorta.":[46],"Among":[47],"several":[48],"key":[49],"VAD":[50],"system":[51,66],"improvements,":[52],"has":[55],"smaller":[57],"body":[58],"size":[59],"than":[60],"other":[61],"LVADs":[62],"its":[64],"maglev":[65],"offers":[67],"large-gap":[69],"design":[70],"that":[71,118],"makes":[72],"it":[73],"superior":[74],"terms":[76],"hemocompatibility.":[78],"In":[79],"this":[80],"study,":[81,131],"we":[82],"calf":[88],"evaluated":[90],"hemodynamic":[92,101,122],"hemocompatibility":[94],"characteristics":[95],"over":[96],"14-day":[98],"period.":[99],"parameters,":[102],"pump":[104],"data,":[105],"blood":[107],"test":[108],"results":[109,116,142],"were":[110,137],"recorded":[111],"throughout":[112,129],"study.":[114],"showed":[117,143],"provided":[121],"stability.":[123],"Hemocompatibility":[124],"testing":[125],"indicated":[126],"negligible":[127],"hemolysis":[128],"no":[133,183],"signs":[134],"infection":[136],"seen.":[138],"On":[139],"necropsy,":[140],"only":[144],"expected":[145],"focal":[146],"mild-to-moderate":[147],"adhesions":[148],"between":[149,162],"pericardial":[151,164],"sac":[152,165],"(along":[153],"pump)":[155],"adjacent":[158],"rib":[159],"cage,":[160],"heart.":[168],"Gross":[169],"examination":[170],"internal":[172],"organs":[173],"was":[174],"unremarkable.":[175],"Examination":[176],"after":[180],"explantation":[181],"revealed":[182],"evidence":[184],"thrombus":[186],"formation":[187],"internally":[188],"or":[189,193],"around":[190],"cannulas.":[195]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}