{"id":"https://openalex.org/W2899308242","doi":"https://doi.org/10.1109/embc.2018.8513097","title":"Automatic Segmentation of Neonatal Ventricles from Cranial Ultrasound for Prediction of Intraventricular Hemorrhage Outcome","display_name":"Automatic Segmentation of Neonatal Ventricles from Cranial Ultrasound for Prediction of Intraventricular Hemorrhage Outcome","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2899308242","doi":"https://doi.org/10.1109/embc.2018.8513097","mag":"2899308242","pmid":"https://pubmed.ncbi.nlm.nih.gov/30441059"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8513097","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513097","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111734756","display_name":"Pooneh R. Tabrizi","orcid":null},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pooneh R. Tabrizi","raw_affiliation_strings":["Children\u2019s National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA","Children's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA"],"affiliations":[{"raw_affiliation_string":"Children\u2019s National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]},{"raw_affiliation_string":"Children's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084898491","display_name":"Rawad Obeid","orcid":"https://orcid.org/0000-0003-1762-9174"},"institutions":[{"id":"https://openalex.org/I2801344670","display_name":"Community Health Systems - Dupont Hospital","ror":"https://ror.org/03753r186","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801344670","https://openalex.org/I4405259010"]},{"id":"https://openalex.org/I1316910977","display_name":"DuPont (United States)","ror":"https://ror.org/03g3m1w62","country_code":"US","type":"company","lineage":["https://openalex.org/I1316910977"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rawad Obeid","raw_affiliation_strings":["Neurology Department, Nemours/DuPont Hospital for Children, Wilmington, DE, USA"],"affiliations":[{"raw_affiliation_string":"Neurology Department, Nemours/DuPont Hospital for Children, Wilmington, DE, USA","institution_ids":["https://openalex.org/I2801344670","https://openalex.org/I1316910977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051073355","display_name":"Juan J. Cerrolaza","orcid":null},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Juan J. Cerrolaza","raw_affiliation_strings":["Imperial College London, London, London, GB"],"affiliations":[{"raw_affiliation_string":"Imperial College London, London, London, GB","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023513227","display_name":"Anna A. Penn","orcid":"https://orcid.org/0000-0003-1539-5220"},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Penn","raw_affiliation_strings":["Fetal Medicine, Center of Neuroscience Research, Neonatology form the Children\u2019s National Health System, Washington, DC, USA","Fetal Medicine, Center of Neuroscience Research, Neonatology form the Children's National Health System, Washington, DC, USA"],"affiliations":[{"raw_affiliation_string":"Fetal Medicine, Center of Neuroscience Research, Neonatology form the Children\u2019s National Health System, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]},{"raw_affiliation_string":"Fetal Medicine, Center of Neuroscience Research, Neonatology form the Children's National Health System, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086340207","display_name":"Awais Mansoor","orcid":"https://orcid.org/0000-0001-6761-8030"},"institutions":[{"id":"https://openalex.org/I1336742384","display_name":"Children's National","ror":"https://ror.org/03wa2q724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1336742384"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Awais Mansoor","raw_affiliation_strings":["Children\u2019s National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA","Children's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA"],"affiliations":[{"raw_affiliation_string":"Children\u2019s National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]},{"raw_affiliation_string":"Children's National Health System, Sheikh Zayed Institute for Pediatric Surgical Innovation, Washington, DC, USA","institution_ids":["https://openalex.org/I1336742384"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085732379","display_name":"Marius George Linguraru","orcid":"https://orcid.org/0000-0001-6175-8665"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marius George Linguraru","raw_affiliation_strings":["George Washington University Law School, Washington, DC, US"],"affiliations":[{"raw_affiliation_string":"George Washington University Law School, Washington, DC, US","institution_ids":["https://openalex.org/I193531525"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5111734756"],"corresponding_institution_ids":["https://openalex.org/I1336742384"],"apc_list":null,"apc_paid":null,"fwci":1.822,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.87144924,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2018","issue":null,"first_page":"3136","last_page":"3139"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12552","display_name":"Fetal and Pediatric Neurological Disorders","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lateral-ventricles","display_name":"Lateral ventricles","score":0.7662665843963623},{"id":"https://openalex.org/keywords/intraventricular-hemorrhage","display_name":"Intraventricular hemorrhage","score":0.743806779384613},{"id":"https://openalex.org/keywords/cerebral-ventricle","display_name":"Cerebral ventricle","score":0.6755595207214355},{"id":"https://openalex.org/keywords/ventricle","display_name":"Ventricle","score":0.5609545707702637},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5175884962081909},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.506227433681488},{"id":"https://openalex.org/keywords/ultrasound","display_name":"Ultrasound","score":0.4960075318813324},{"id":"https://openalex.org/keywords/hydrocephalus","display_name":"Hydrocephalus","score":0.4943807125091553},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.4085327684879303},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3197649419307709},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2745617926120758},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.26829561591148376},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2472178041934967},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.1941983699798584},{"id":"https://openalex.org/keywords/gestational-age","display_name":"Gestational age","score":0.09098127484321594}],"concepts":[{"id":"https://openalex.org/C2780744974","wikidata":"https://www.wikidata.org/wiki/Q1929623","display_name":"Lateral ventricles","level":2,"score":0.7662665843963623},{"id":"https://openalex.org/C2779252433","wikidata":"https://www.wikidata.org/wiki/Q6058597","display_name":"Intraventricular hemorrhage","level":4,"score":0.743806779384613},{"id":"https://openalex.org/C2993827019","wikidata":"https://www.wikidata.org/wiki/Q105402","display_name":"Cerebral ventricle","level":2,"score":0.6755595207214355},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.5609545707702637},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5175884962081909},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.506227433681488},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.4960075318813324},{"id":"https://openalex.org/C2778134817","wikidata":"https://www.wikidata.org/wiki/Q193003","display_name":"Hydrocephalus","level":2,"score":0.4943807125091553},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4085327684879303},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3197649419307709},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2745617926120758},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.26829561591148376},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2472178041934967},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1941983699798584},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.09098127484321594},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002543","descriptor_name":"Cerebral Hemorrhage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002543","descriptor_name":"Cerebral Hemorrhage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002543","descriptor_name":"Cerebral Hemorrhage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004453","descriptor_name":"Echoencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004453","descriptor_name":"Echoencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004453","descriptor_name":"Echoencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006849","descriptor_name":"Hydrocephalus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006849","descriptor_name":"Hydrocephalus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006849","descriptor_name":"Hydrocephalus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2018.8513097","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8513097","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30441059","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30441059","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7900000214576721}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1156767201","https://openalex.org/W1962010357","https://openalex.org/W1988725196","https://openalex.org/W1991188161","https://openalex.org/W1998259955","https://openalex.org/W2003099669","https://openalex.org/W2040463271","https://openalex.org/W2044164591","https://openalex.org/W2048325419","https://openalex.org/W2051304144","https://openalex.org/W2085882649","https://openalex.org/W2096027555","https://openalex.org/W2115664739","https://openalex.org/W2466670129","https://openalex.org/W2547324937","https://openalex.org/W2587490412","https://openalex.org/W2755505179","https://openalex.org/W6640974819"],"related_works":["https://openalex.org/W2095387627","https://openalex.org/W1974731343","https://openalex.org/W2020375913","https://openalex.org/W4232542766","https://openalex.org/W4210370215","https://openalex.org/W2030132795","https://openalex.org/W1985288215","https://openalex.org/W4306253611","https://openalex.org/W2125469686","https://openalex.org/W2047684574"],"abstract_inverted_index":{"Intraventricular":[0],"hemorrhage":[1],"(IVH)":[2],"followed":[3],"by":[4],"post":[5],"hemorrhagic":[6],"hydrocephalus":[7],"(PHH)":[8],"in":[9,21,66,83],"premature":[10,153],"neonates":[11,40,67,154],"is":[12,26],"one":[13],"of":[14,18,51,55,101,115,138,141,146,174,188,220,235],"the":[15,49,63,89,98,105,136,139,186,192,214,218],"recognized":[16],"reasons":[17],"brain":[19,90,94,106],"injury":[20],"newborns.":[22],"Cranial":[23],"ultrasound":[24],"(CUS)":[25],"a":[27,76,113,144,226],"noninvasive":[28],"imaging":[29],"tool":[30,229],"that":[31,162],"has":[32,213],"been":[33],"used":[34],"widely":[35],"to":[36,61,96,199,216],"diagnose":[37],"and":[38,93,103,120,223,233,237],"monitor":[39],"with":[41,68,131,155,168,196],"IVH.":[42,69],"In":[43,70,178],"our":[44,132,163,180,200],"previous":[45,133,201],"work,":[46],"we":[47,73,125],"showed":[48,161],"potential":[50,215],"quantitative":[52],"morphological":[53],"analysis":[54],"lateral":[56],"ventricles":[57,102,109,167],"from":[58,151],"early":[59,231],"CUS":[60,85,148,221],"predict":[62,185],"PHH":[64,142,189],"outcome":[65,140,187],"this":[71,127],"paper,":[72],"first":[74],"present":[75],"new":[77],"automatic":[78],"method":[79,164,183,212],"for":[80,135,230],"ventricle":[81,194],"segmentation":[82],"2D":[84,147],"images.":[86],"We":[87],"detect":[88],"bounding":[91],"box":[92],"mid-line":[95],"estimate":[97],"anatomical":[99],"positions":[100],"correct":[104],"rotation.":[107],"The":[108],"are":[110],"segmented":[111],"using":[112],"combination":[114],"fuzzy":[116],"c-means,":[117],"phase":[118],"congruency,":[119],"active":[121],"contour":[122],"algorithms.":[123],"Finally,":[124],"compare":[126],"fully":[128,181],"automated":[129,182],"approach":[130,203],"work":[134],"prediction":[137],"on":[143,191],"set":[145],"images":[149,222],"taken":[150],"60":[152],"different":[156],"IVH":[157,236],"grades.":[158],"Experimental":[159],"results":[160],"could":[165,184],"segment":[166],"an":[169],"average":[170],"Dice":[171],"similarity":[172],"coefficient":[173],"0.8":[175],"\u00b1":[176],"0.12.":[177],"addition,":[179],"based":[190],"extracted":[193],"regions":[195],"similar":[197],"accuracy":[198],"semi-automated":[202],"(83%":[204],"vs.":[205],"84%,":[206],"respectively,":[207],"p-value":[208],"=":[209],"0.8).":[210],"This":[211],"standardize":[217],"evaluation":[219],"can":[224],"be":[225],"helpful":[227],"clinical":[228],"monitoring":[232],"treatment":[234],"PHH.":[238]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2025-11-25T21:42:39.735039","created_date":"2025-10-10T00:00:00"}