{"id":"https://openalex.org/W2898909737","doi":"https://doi.org/10.1109/embc.2018.8512185","title":"A Bayesian parametric model for quantifying brain maturation from sleep-EEG in the vulnerable newborn baby","display_name":"A Bayesian parametric model for quantifying brain maturation from sleep-EEG in the vulnerable newborn baby","publication_year":2018,"publication_date":"2018-07-01","ids":{"openalex":"https://openalex.org/W2898909737","doi":"https://doi.org/10.1109/embc.2018.8512185","mag":"2898909737","pmid":"https://pubmed.ncbi.nlm.nih.gov/30440242"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2018.8512185","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8512185","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034926138","display_name":"Kirubin Pillay","orcid":"https://orcid.org/0000-0001-9269-2881"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Kirubin Pillay","raw_affiliation_strings":["University of Oxford, Oxford, Oxfordshire, GB"],"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, Oxfordshire, GB","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054781337","display_name":"A Dereymaeker","orcid":"https://orcid.org/0000-0003-3923-1298"},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Anneleen Dereymaeker","raw_affiliation_strings":["Katholieke Universiteit Leuven, Leuven, Flanders, BE"],"affiliations":[{"raw_affiliation_string":"Katholieke Universiteit Leuven, Leuven, Flanders, BE","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019146143","display_name":"Katrien Jansen","orcid":"https://orcid.org/0000-0002-5503-529X"},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Katrien Jansen","raw_affiliation_strings":["Katholieke Universiteit Leuven, Leuven, Flanders, BE"],"affiliations":[{"raw_affiliation_string":"Katholieke Universiteit Leuven, Leuven, Flanders, BE","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016413752","display_name":"Gunnar Naulaers","orcid":"https://orcid.org/0000-0003-0735-4808"},"institutions":[{"id":"https://openalex.org/I99464096","display_name":"KU Leuven","ror":"https://ror.org/05f950310","country_code":"BE","type":"education","lineage":["https://openalex.org/I99464096"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Gunnar Naulaers","raw_affiliation_strings":["Katholieke Universiteit Leuven, Leuven, Flanders, BE"],"affiliations":[{"raw_affiliation_string":"Katholieke Universiteit Leuven, Leuven, Flanders, BE","institution_ids":["https://openalex.org/I99464096"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064593698","display_name":"Maarten De Vos","orcid":"https://orcid.org/0000-0002-3482-5145"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Maarten De Vos","raw_affiliation_strings":["University of Oxford, Oxford, Oxfordshire, GB"],"affiliations":[{"raw_affiliation_string":"University of Oxford, Oxford, Oxfordshire, GB","institution_ids":["https://openalex.org/I40120149"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5034926138"],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":null,"apc_paid":null,"fwci":0.3644,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.70434632,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"128","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9896000027656555,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.6806856393814087},{"id":"https://openalex.org/keywords/sleep","display_name":"Sleep (system call)","score":0.6058275103569031},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.4999735355377197},{"id":"https://openalex.org/keywords/parametric-statistics","display_name":"Parametric statistics","score":0.4340299665927887},{"id":"https://openalex.org/keywords/brain-development","display_name":"Brain development","score":0.426440566778183},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.38581883907318115},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3735414743423462},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3133733868598938},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.27377742528915405},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2593430280685425},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.18711528182029724},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1651819944381714},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1577315628528595}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.6806856393814087},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.6058275103569031},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.4999735355377197},{"id":"https://openalex.org/C117251300","wikidata":"https://www.wikidata.org/wiki/Q1849855","display_name":"Parametric statistics","level":2,"score":0.4340299665927887},{"id":"https://openalex.org/C2984223407","wikidata":"https://www.wikidata.org/wiki/Q1345738","display_name":"Brain development","level":2,"score":0.426440566778183},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.38581883907318115},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3735414743423462},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3133733868598938},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.27377742528915405},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2593430280685425},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.18711528182029724},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1651819944381714},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1577315628528595},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012894","descriptor_name":"Sleep Stages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012894","descriptor_name":"Sleep Stages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012894","descriptor_name":"Sleep Stages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2018.8512185","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2018.8512185","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:30440242","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30440242","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:lirias2repo.kuleuven.be:123456789/633247","is_oa":false,"landing_page_url":"https://lirias.kuleuven.be/bitstream/123456789/633247/2/bayesian.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401954","display_name":"Lirias (KU Leuven)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I99464096","host_organization_name":"KU Leuven","host_organization_lineage":["https://openalex.org/I99464096"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"40th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC), HI, Honolulu, 18-21 July 2018","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1556848471","https://openalex.org/W1579271636","https://openalex.org/W2012506627","https://openalex.org/W2013378101","https://openalex.org/W2061504941","https://openalex.org/W2115812401","https://openalex.org/W2124141570","https://openalex.org/W2175639254","https://openalex.org/W2416402053","https://openalex.org/W2488678869","https://openalex.org/W2589719932","https://openalex.org/W2595353633","https://openalex.org/W2734420566","https://openalex.org/W2759717405","https://openalex.org/W2761594644","https://openalex.org/W2793410326"],"related_works":["https://openalex.org/W2922348724","https://openalex.org/W200322357","https://openalex.org/W2130428257","https://openalex.org/W4308951944","https://openalex.org/W2057366091","https://openalex.org/W4312960290","https://openalex.org/W2049513647","https://openalex.org/W2988848585","https://openalex.org/W4233722919","https://openalex.org/W4323929055"],"abstract_inverted_index":{"Newborn":[0],"babies,":[1],"particularly":[2],"preterms,":[3],"can":[4],"exhibit":[5],"early":[6],"deviations":[7,44,163],"in":[8],"sleep":[9,36,73,107,115],"maturation":[10,109],"as":[11,96],"seen":[12],"by":[13,24],"Electroencephalogram":[14],"(EEG)":[15],"recordings.":[16],"This":[17],"may":[18],"be":[19],"indicative":[20],"of":[21,64,119],"cognitive":[22],"problems":[23],"school-age.":[25],"The":[26,157],"current":[27],"'clinically-driven'":[28],"approach":[29],"uses":[30],"separate":[31],"algorithms":[32,75],"to":[33,101,142,160],"first":[34],"extract":[35],"states":[37],"and":[38],"then":[39],"predict":[40],"EEG":[41],"'brain-age'.":[42],"Maturational":[43],"are":[45],"identified":[46],"when":[47],"the":[48,53,57,60,65,68,83,147],"brain-age":[49,87],"no":[50],"longer":[51],"matches":[52],"Postmenstrual":[54],"Age":[55],"(PMA,":[56],"age":[58],"since":[59],"last":[61],"menstrual":[62],"cycle":[63],"mother).":[66],"However,":[67],"PMA":[69,84],"range":[70,85],"where":[71],"existing":[72],"staging":[74,116],"perform":[76],"optimally,":[77],"is":[78,164],"limited,":[79],"which":[80],"subsequently":[81],"limits":[82],"for":[86,106],"prediction.":[88],"We":[89],"introduce":[90],"a":[91,97,112,123,128,168],"Bayesian":[92],"Parametric":[93],"Model":[94],"(BPM)":[95],"single":[98],"end-to-end":[99],"solution":[100],"directly":[102],"estimate":[103],"brain-age,":[104],"modelling":[105],"state":[108],"without":[110],"requiring":[111],"separately":[113],"optimized":[114],"algorithm.":[117],"Comparison":[118],"this":[120],"model":[121],"with":[122,146],"traditional":[124],"multi-stage":[125],"approach,":[126],"yields":[127],"similar":[129],"Krippendorff's":[130],"$\\alpha":[131],"=":[132],"0.92$":[133],"(a":[134],"performance":[135],"measure":[136],"ranging":[137],"from":[138],"0":[139],"(chance":[140],"agreement)":[141],"1":[143],"(perfect":[144],"agreement))":[145],"BPM":[148],"performing":[149],"better":[150],"at":[151,175],"younger":[152],"ages":[153],"<30":[154],"weeks":[155],"PMA.":[156],"BPM's":[158],"potential":[159],"detect":[161],"maturational":[162],"also":[165],"explored":[166],"on":[167],"few":[169],"preterm":[170],"babies":[171],"who":[172],"were":[173],"abnormal":[174],"9":[176],"months":[177],"follow-up.":[178]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}