{"id":"https://openalex.org/W2754329110","doi":"https://doi.org/10.1109/embc.2017.8037521","title":"Multiscale sample entropy of heart rate and blood pressure: Methodological aspects","display_name":"Multiscale sample entropy of heart rate and blood pressure: Methodological aspects","publication_year":2017,"publication_date":"2017-07-01","ids":{"openalex":"https://openalex.org/W2754329110","doi":"https://doi.org/10.1109/embc.2017.8037521","mag":"2754329110","pmid":"https://pubmed.ncbi.nlm.nih.gov/29060562"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2017.8037521","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8037521","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072104330","display_name":"Paolo Castiglioni","orcid":"https://orcid.org/0000-0002-8775-2605"},"institutions":[{"id":"https://openalex.org/I4210116940","display_name":"Don Carlo Gnocchi Foundation","ror":"https://ror.org/02e3ssq97","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210116940"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Castiglioni","raw_affiliation_strings":["IRCCS Fondazione Don C. Gnocchi, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Fondazione Don C. Gnocchi, Milan, Italy","institution_ids":["https://openalex.org/I4210116940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103752566","display_name":"Lorenzo Brambilla","orcid":null},"institutions":[{"id":"https://openalex.org/I4210116940","display_name":"Don Carlo Gnocchi Foundation","ror":"https://ror.org/02e3ssq97","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210116940"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lorenzo Brambilla","raw_affiliation_strings":["Fondazione Don C. Gnocchi, Parma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione Don C. Gnocchi, Parma, Italy","institution_ids":["https://openalex.org/I4210116940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027818970","display_name":"Matteo Bini","orcid":"https://orcid.org/0000-0002-8836-4145"},"institutions":[{"id":"https://openalex.org/I124601658","display_name":"University of Parma","ror":"https://ror.org/02k7wn190","country_code":"IT","type":"education","lineage":["https://openalex.org/I124601658"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Matteo Bini","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy","institution_ids":["https://openalex.org/I124601658"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032967474","display_name":"Paolo Coruzzi","orcid":"https://orcid.org/0000-0001-9590-4341"},"institutions":[{"id":"https://openalex.org/I124601658","display_name":"University of Parma","ror":"https://ror.org/02k7wn190","country_code":"IT","type":"education","lineage":["https://openalex.org/I124601658"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo Coruzzi","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy","institution_ids":["https://openalex.org/I124601658"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063035109","display_name":"Andrea Faini","orcid":"https://orcid.org/0000-0002-8924-8234"},"institutions":[{"id":"https://openalex.org/I4210134201","display_name":"IRCCS Istituto Auxologico Italiano","ror":"https://ror.org/033qpss18","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]},{"id":"https://openalex.org/I4210153126","display_name":"Istituti di Ricovero e Cura a Carattere Scientifico","ror":"https://ror.org/04tfzc498","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Faini","raw_affiliation_strings":["IRCCS Istituto Auxologico Italiano, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Istituto Auxologico Italiano, Milan, Italy","institution_ids":["https://openalex.org/I4210134201","https://openalex.org/I4210153126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.12323612,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"278","issue":null,"first_page":"3134","last_page":"3137"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11270","display_name":"Complex Systems and Time Series Analysis","score":0.9703999757766724,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sample-entropy","display_name":"Sample entropy","score":0.8033307790756226},{"id":"https://openalex.org/keywords/estimator","display_name":"Estimator","score":0.6738806962966919},{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"Heart rate variability","score":0.5451409816741943},{"id":"https://openalex.org/keywords/granularity","display_name":"Granularity","score":0.5103611350059509},{"id":"https://openalex.org/keywords/entropy","display_name":"Entropy (arrow of time)","score":0.4741489291191101},{"id":"https://openalex.org/keywords/rr-interval","display_name":"RR interval","score":0.45534735918045044},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.45314180850982666},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.45207950472831726},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.44791093468666077},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.39581409096717834},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.34400731325149536},{"id":"https://openalex.org/keywords/time-series","display_name":"Time series","score":0.21764525771141052},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15420043468475342},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.146086186170578},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.07858914136886597}],"concepts":[{"id":"https://openalex.org/C66696666","wikidata":"https://www.wikidata.org/wiki/Q17105612","display_name":"Sample entropy","level":3,"score":0.8033307790756226},{"id":"https://openalex.org/C185429906","wikidata":"https://www.wikidata.org/wiki/Q1130160","display_name":"Estimator","level":2,"score":0.6738806962966919},{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.5451409816741943},{"id":"https://openalex.org/C177774035","wikidata":"https://www.wikidata.org/wiki/Q1246948","display_name":"Granularity","level":2,"score":0.5103611350059509},{"id":"https://openalex.org/C106301342","wikidata":"https://www.wikidata.org/wiki/Q4117933","display_name":"Entropy (arrow of time)","level":2,"score":0.4741489291191101},{"id":"https://openalex.org/C2908688587","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"RR interval","level":5,"score":0.45534735918045044},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.45314180850982666},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.45207950472831726},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.44791093468666077},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.39581409096717834},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.34400731325149536},{"id":"https://openalex.org/C151406439","wikidata":"https://www.wikidata.org/wiki/Q186588","display_name":"Time series","level":2,"score":0.21764525771141052},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15420043468475342},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.146086186170578},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07858914136886597},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001795","descriptor_name":"Blood Pressure Determination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001795","descriptor_name":"Blood Pressure Determination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001795","descriptor_name":"Blood Pressure Determination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012146","descriptor_name":"Rest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012146","descriptor_name":"Rest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012146","descriptor_name":"Rest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019277","descriptor_name":"Entropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019277","descriptor_name":"Entropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019277","descriptor_name":"Entropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2017.8037521","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8037521","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:29060562","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29060562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:irinsubria.uninsubria.it:11383/2145214","is_oa":false,"landing_page_url":"https://hdl.handle.net/11383/2145214","pdf_url":null,"source":{"id":"https://openalex.org/S4377196351","display_name":"IrInSubria (University of Insubria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I115752224","host_organization_name":"University of Insubria","host_organization_lineage":["https://openalex.org/I115752224"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.75}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1186463519","https://openalex.org/W1862394037","https://openalex.org/W1993194004","https://openalex.org/W2049571914","https://openalex.org/W2059851411","https://openalex.org/W2097657338","https://openalex.org/W2139470039","https://openalex.org/W2150123009","https://openalex.org/W2168764150","https://openalex.org/W2473644366","https://openalex.org/W2508912663"],"related_works":["https://openalex.org/W3088843374","https://openalex.org/W1976653534","https://openalex.org/W2142558988","https://openalex.org/W1502524017","https://openalex.org/W2062266966","https://openalex.org/W3014430990","https://openalex.org/W2946788172","https://openalex.org/W2022287597","https://openalex.org/W2444442705","https://openalex.org/W3025473760"],"abstract_inverted_index":{"The":[0,72,111],"entropy":[1,36],"of":[2,8,15,28,45,57,69,82,104,138,156,165,185,192],"heart":[3,116,166],"rate":[4,117],"variability":[5],"is":[6,60,99,175],"one":[7],"the":[9,13,16,25,43,76,95,97,108,171,173,182,189],"main":[10],"features":[11],"characterizing":[12],"complexity":[14],"cardiovascular":[17,29,70,186],"system.":[18],"In":[19],"order":[20],"to":[21,34,61,67,153],"take":[22],"into":[23],"account":[24],"multiscale":[26,39],"nature":[27],"regulation,":[30],"it":[31],"was":[32],"proposed":[33],"evaluate":[35],"with":[37],"a":[38,80,88],"approach,":[40],"based":[41],"on":[42,48],"estimation":[44],"Sample":[46,53],"Entropy":[47],"progressively":[49],"coarse-grained":[50],"series":[51,155],"(Multiscale":[52],"Entropy,":[54],"MSE).":[55],"Aim":[56],"this":[58],"work":[59],"investigate":[62,129],"two":[63],"methodological":[64],"aspects":[65],"related":[66],"MSE":[68,109,127,151,183],"signals.":[71],"first":[73],"aspect":[74,113],"regards":[75,114],"tolerance":[77,98,174],"below":[78],"which":[79],"couple":[81],"points":[83],"are":[84,123],"considered":[85],"similar":[86],"in":[87,92,143],"given":[89],"embedding":[90],"dimension,":[91],"particular":[93],"how":[94],"way":[96,172],"set":[100,176],"at":[101,147],"each":[102],"level":[103,191],"coarse":[105,178],"graining":[106,179],"influences":[107,180],"estimates.":[110],"second":[112],"whether":[115],"and":[118,149,161],"blood":[119],"pressure":[120],"(BP)":[121],"signals":[122],"characterized":[124],"by":[125],"different":[126],"structures.To":[128],"these":[130],"aspects,":[131],"we":[132],"analyzed":[133],"65":[134],"continuous":[135],"BP":[136,160],"recordings":[137],"more":[139],"than":[140],"90-minute":[141],"duration":[142],"healthy":[144],"volunteers":[145],"sitting":[146],"rest,":[148],"applied":[150],"estimators":[152],"beat-by-beat":[154],"systolic":[157],"BP,":[158],"diastolic":[159],"pulse":[162],"interval":[163],"(inverse":[164],"rate).":[167],"Results":[168],"indicate":[169],"that":[170],"during":[177],"substantially":[181],"profile":[184],"signals,":[187],"modifying":[188],"relative":[190],"their":[193],"unpredictability.":[194]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}