{"id":"https://openalex.org/W2754775148","doi":"https://doi.org/10.1109/embc.2017.8037424","title":"An in silico method to predict net calcium transfer during hemodialysis","display_name":"An in silico method to predict net calcium transfer during hemodialysis","publication_year":2017,"publication_date":"2017-07-01","ids":{"openalex":"https://openalex.org/W2754775148","doi":"https://doi.org/10.1109/embc.2017.8037424","mag":"2754775148","pmid":"https://pubmed.ncbi.nlm.nih.gov/29060465"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2017.8037424","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8037424","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043874351","display_name":"Vaibhav Maheshwari","orcid":null},"institutions":[{"id":"https://openalex.org/I4210124297","display_name":"Renal Research Institute","ror":"https://ror.org/032g46r36","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124297"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Vaibhav Maheshwari","raw_affiliation_strings":["Renal Research Institute, New York City, NY"],"affiliations":[{"raw_affiliation_string":"Renal Research Institute, New York City, NY","institution_ids":["https://openalex.org/I4210124297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047222128","display_name":"Alhaji Cherif","orcid":"https://orcid.org/0000-0001-8654-2772"},"institutions":[{"id":"https://openalex.org/I4210124297","display_name":"Renal Research Institute","ror":"https://ror.org/032g46r36","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124297"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alhaji Cherif","raw_affiliation_strings":["Renal Research Institute, New York City, NY"],"affiliations":[{"raw_affiliation_string":"Renal Research Institute, New York City, NY","institution_ids":["https://openalex.org/I4210124297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011848948","display_name":"Doris H. Fuertinger","orcid":"https://orcid.org/0000-0001-6321-2367"},"institutions":[{"id":"https://openalex.org/I4210124297","display_name":"Renal Research Institute","ror":"https://ror.org/032g46r36","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124297"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Doris Fuertinger","raw_affiliation_strings":["Renal Research Institute, New York City, NY"],"affiliations":[{"raw_affiliation_string":"Renal Research Institute, New York City, NY","institution_ids":["https://openalex.org/I4210124297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080629146","display_name":"Gudrun Schappacher\u2010Tilp","orcid":"https://orcid.org/0000-0001-9078-0044"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gudrun Schappacher-Tilp","raw_affiliation_strings":["Institute for Analysis and Numerical Theory, Graz, TU, Austria"],"affiliations":[{"raw_affiliation_string":"Institute for Analysis and Numerical Theory, Graz, TU, Austria","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039827277","display_name":"Priscila Preciado","orcid":"https://orcid.org/0000-0002-3841-0414"},"institutions":[{"id":"https://openalex.org/I4210124297","display_name":"Renal Research Institute","ror":"https://ror.org/032g46r36","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124297"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Priscila Preciado","raw_affiliation_strings":["Renal Research Institute, New York City, NY"],"affiliations":[{"raw_affiliation_string":"Renal Research Institute, New York City, NY","institution_ids":["https://openalex.org/I4210124297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045091218","display_name":"Stephan Thijssen","orcid":null},"institutions":[{"id":"https://openalex.org/I4210124297","display_name":"Renal Research Institute","ror":"https://ror.org/032g46r36","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124297"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephan Thijssen","raw_affiliation_strings":["Renal Research Institute, New York City, NY"],"affiliations":[{"raw_affiliation_string":"Renal Research Institute, New York City, NY","institution_ids":["https://openalex.org/I4210124297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091483213","display_name":"David A. Bushinsky","orcid":"https://orcid.org/0000-0002-4030-2922"},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medical Center","ror":"https://ror.org/00trqv719","country_code":"US","type":"funder","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David A. Bushinsky","raw_affiliation_strings":["University of Rochester Medical Center, School of Medicine and Dentistry, Rochester, NY"],"affiliations":[{"raw_affiliation_string":"University of Rochester Medical Center, School of Medicine and Dentistry, Rochester, NY","institution_ids":["https://openalex.org/I28792581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022002223","display_name":"Peter Kotanko","orcid":"https://orcid.org/0000-0003-4373-412X"},"institutions":[{"id":"https://openalex.org/I4210124297","display_name":"Renal Research Institute","ror":"https://ror.org/032g46r36","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210124297"]},{"id":"https://openalex.org/I1320796813","display_name":"Mount Sinai Health System","ror":"https://ror.org/04kfn4587","country_code":"US","type":"funder","lineage":["https://openalex.org/I1320796813"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Kotanko","raw_affiliation_strings":["Adjunct Professor of Nephrology in Mount Sinai Health System, New York, USA","Renal Research Institute, New York City, NY"],"affiliations":[{"raw_affiliation_string":"Adjunct Professor of Nephrology in Mount Sinai Health System, New York, USA","institution_ids":["https://openalex.org/I1320796813"]},{"raw_affiliation_string":"Renal Research Institute, New York City, NY","institution_ids":["https://openalex.org/I4210124297"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5043874351"],"corresponding_institution_ids":["https://openalex.org/I4210124297"],"apc_list":null,"apc_paid":null,"fwci":0.4825,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.64518785,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"2017","issue":null,"first_page":"2740","last_page":"2743"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13966","display_name":"Neurological and metabolic disorders","score":0.9830999970436096,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemodialysis","display_name":"Hemodialysis","score":0.8582926988601685},{"id":"https://openalex.org/keywords/calcium","display_name":"Calcium","score":0.8425769805908203},{"id":"https://openalex.org/keywords/dialysis","display_name":"Dialysis","score":0.6931490898132324},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5721805691719055},{"id":"https://openalex.org/keywords/calcification","display_name":"Calcification","score":0.5403615832328796},{"id":"https://openalex.org/keywords/albumin","display_name":"Albumin","score":0.4173937141895294},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3789038360118866},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.3777426481246948},{"id":"https://openalex.org/keywords/urology","display_name":"Urology","score":0.355253130197525},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3252810835838318},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.1905684471130371}],"concepts":[{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.8582926988601685},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.8425769805908203},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.6931490898132324},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5721805691719055},{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.5403615832328796},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.4173937141895294},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3789038360118866},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3777426481246948},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.355253130197525},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3252810835838318},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1905684471130371}],"mesh":[{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015314","descriptor_name":"Dialysis Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015314","descriptor_name":"Dialysis Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015314","descriptor_name":"Dialysis Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2017.8037424","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8037424","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:29060465","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29060465","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8299999833106995}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W50066389","https://openalex.org/W1980035652","https://openalex.org/W2017246713","https://openalex.org/W2048981263","https://openalex.org/W2116129839","https://openalex.org/W2528842115","https://openalex.org/W2585854883","https://openalex.org/W4300440215"],"related_works":["https://openalex.org/W2365274035","https://openalex.org/W3032525078","https://openalex.org/W2375297571","https://openalex.org/W1994693750","https://openalex.org/W2971160620","https://openalex.org/W2131714067","https://openalex.org/W2353416011","https://openalex.org/W2390999535","https://openalex.org/W2139863994","https://openalex.org/W2353267380"],"abstract_inverted_index":{"International":[0],"guidelines":[1],"for":[2,84,94],"chronic":[3],"hemodialysis":[4,41,147],"patients":[5,115],"suggest":[6,101],"a":[7,60,104,134,140],"dialysate":[8,23,106,128],"calcium":[9,24,29,52,76,107,120,125],"concentration":[10,108],"between":[11],"1.25":[12,110],"and":[13,65,73,87],"1.5":[14],"mmol/L.":[15],"However,":[16],"it":[17,43],"is":[18,44],"not":[19],"certain":[20],"if":[21],"these":[22],"levels":[25],"result":[26],"in":[27,40,146],"net":[28,124],"transfer":[30],"into":[31],"the":[32,48,75,91,95],"patient.":[33],"With":[34],"ubiquitous":[35],"prevalence":[36],"of":[37,51,68,109,113,143],"vascular":[38,138],"calcification":[39],"patients,":[42],"pertinent":[45],"to":[46,71,129,137],"model":[47,64,70,82,99],"mass":[49,77],"balance":[50,78],"during":[53,79,121],"dialysis.":[54,80,122],"To":[55],"this":[56],"end,":[57],"we":[58],"developed":[59],"two":[61],"compartmental":[62],"patient":[63],"spatiotemporal":[66],"representation":[67],"dialyzer":[69],"investigate":[72],"quantify":[74],"The":[81,98],"accounts":[83,93],"calcium-albumin":[85],"binding":[86],"varying":[88],"protein":[89],"concentration;":[90],"latter":[92],"Gibbs-Donnan":[96],"effect.":[97],"simulations":[100],"that":[102],"despite":[103],"lower":[105],"mmol/L,":[111],"some":[112],"our":[114],"may":[116,132],"be":[117,133],"loaded":[118],"with":[119],"This":[123],"flux":[126],"from":[127],"blood":[130],"side":[131],"potential":[135],"contributor":[136],"calcification,":[139],"primary":[141],"cause":[142],"cardiovascular":[144],"mortality":[145],"patients.":[148]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2020,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}