{"id":"https://openalex.org/W2754310951","doi":"https://doi.org/10.1109/embc.2017.8037418","title":"A continuum model of electrical stimulation of multi-compartmental retinal ganglion cells","display_name":"A continuum model of electrical stimulation of multi-compartmental retinal ganglion cells","publication_year":2017,"publication_date":"2017-07-01","ids":{"openalex":"https://openalex.org/W2754310951","doi":"https://doi.org/10.1109/embc.2017.8037418","mag":"2754310951","pmid":"https://pubmed.ncbi.nlm.nih.gov/29060460"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2017.8037418","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8037418","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://unsworks.unsw.edu.au/bitstreams/d210ab5b-0359-425a-b5e9-5207b984bede/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080131741","display_name":"Abdulrahman Alqahtani","orcid":"https://orcid.org/0000-0002-6658-3240"},"institutions":[{"id":"https://openalex.org/I195631090","display_name":"Majmaah University","ror":"https://ror.org/01mcrnj60","country_code":"SA","type":"education","lineage":["https://openalex.org/I195631090"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Abdulrahman Alqahtani","raw_affiliation_strings":["College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Applied Medical Sciences, Majmaah University, Majmaah, Saudi Arabia","institution_ids":["https://openalex.org/I195631090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091401352","display_name":"Amr Al Abed","orcid":"https://orcid.org/0000-0002-5560-4771"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Amr Al Abed","raw_affiliation_strings":["School of Biomedical Engineering, University of New South Wales, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088113248","display_name":"Tianruo Guo","orcid":"https://orcid.org/0000-0001-6348-6771"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Tianruo Guo","raw_affiliation_strings":["School of Biomedical Engineering, University of New South Wales, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060602596","display_name":"Nigel H. Lovell","orcid":"https://orcid.org/0000-0003-1637-1079"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Nigel H. Lovell","raw_affiliation_strings":["School of Biomedical Engineering, University of New South Wales, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049381733","display_name":"Socrates Dokos","orcid":"https://orcid.org/0000-0002-7399-2712"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Socrates Dokos","raw_affiliation_strings":["School of Biomedical Engineering, University of New South Wales, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.4851,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.95272727,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2017","issue":null,"first_page":"2716","last_page":"2719"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/soma","display_name":"Soma","score":0.7710915803909302},{"id":"https://openalex.org/keywords/axon","display_name":"Axon","score":0.6410566568374634},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.5947459936141968},{"id":"https://openalex.org/keywords/retina","display_name":"Retina","score":0.588623583316803},{"id":"https://openalex.org/keywords/retinal-ganglion-cell","display_name":"Retinal ganglion cell","score":0.5692244172096252},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5577498078346252},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.5413105487823486},{"id":"https://openalex.org/keywords/phosphene","display_name":"Phosphene","score":0.495564341545105},{"id":"https://openalex.org/keywords/retinal","display_name":"Retinal","score":0.4798850119113922},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.4585556387901306},{"id":"https://openalex.org/keywords/antidromic","display_name":"Antidromic","score":0.4139043986797333},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.380393385887146},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.2998342514038086},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24521809816360474}],"concepts":[{"id":"https://openalex.org/C2779617337","wikidata":"https://www.wikidata.org/wiki/Q842429","display_name":"Soma","level":2,"score":0.7710915803909302},{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.6410566568374634},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5947459936141968},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.588623583316803},{"id":"https://openalex.org/C2777624874","wikidata":"https://www.wikidata.org/wiki/Q927337","display_name":"Retinal ganglion cell","level":3,"score":0.5692244172096252},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5577498078346252},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5413105487823486},{"id":"https://openalex.org/C154145042","wikidata":"https://www.wikidata.org/wiki/Q1072103","display_name":"Phosphene","level":4,"score":0.495564341545105},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.4798850119113922},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.4585556387901306},{"id":"https://openalex.org/C70471684","wikidata":"https://www.wikidata.org/wiki/Q11829331","display_name":"Antidromic","level":3,"score":0.4139043986797333},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.380393385887146},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2998342514038086},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24521809816360474},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C2778581513","wikidata":"https://www.wikidata.org/wiki/Q263962","display_name":"Transcranial magnetic stimulation","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001369","descriptor_name":"Axons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010719","descriptor_name":"Phosphenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010719","descriptor_name":"Phosphenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010719","descriptor_name":"Phosphenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2017.8037418","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8037418","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:29060460","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29060460","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:unsworks.library.unsw.edu.au:1959.4/unsworks_50177","is_oa":true,"landing_page_url":"http://hdl.handle.net/1959.4/unsworks_50177","pdf_url":"https://unsworks.unsw.edu.au/bitstreams/d210ab5b-0359-425a-b5e9-5207b984bede/download","source":{"id":"https://openalex.org/S4306401737","display_name":"UNSWorks (University of New South Wales, Sydney, Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I40053085","host_organization_name":"Australian Defence Force Academy","host_organization_lineage":["https://openalex.org/I40053085"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2017 39th Annual International Conference of the IEEE, Seogwipo, South Korea, 2017-07-11 - 2017-07-15","raw_type":"http://purl.org/coar/resource_type/c_5794"}],"best_oa_location":{"id":"pmh:oai:unsworks.library.unsw.edu.au:1959.4/unsworks_50177","is_oa":true,"landing_page_url":"http://hdl.handle.net/1959.4/unsworks_50177","pdf_url":"https://unsworks.unsw.edu.au/bitstreams/d210ab5b-0359-425a-b5e9-5207b984bede/download","source":{"id":"https://openalex.org/S4306401737","display_name":"UNSWorks (University of New South Wales, Sydney, Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I40053085","host_organization_name":"Australian Defence Force Academy","host_organization_lineage":["https://openalex.org/I40053085"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2017 39th Annual International Conference of the IEEE, Seogwipo, South Korea, 2017-07-11 - 2017-07-15","raw_type":"http://purl.org/coar/resource_type/c_5794"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2754310951.pdf","grobid_xml":"https://content.openalex.org/works/W2754310951.grobid-xml"},"referenced_works_count":9,"referenced_works":["https://openalex.org/W1485335785","https://openalex.org/W1968991873","https://openalex.org/W2002382433","https://openalex.org/W2016775836","https://openalex.org/W2047141148","https://openalex.org/W2051324787","https://openalex.org/W2075146636","https://openalex.org/W2132305173","https://openalex.org/W2434606902"],"related_works":["https://openalex.org/W2078493011","https://openalex.org/W1992691074","https://openalex.org/W2068957919","https://openalex.org/W2132224384","https://openalex.org/W2415197116","https://openalex.org/W2021084130","https://openalex.org/W2029370103","https://openalex.org/W2083880503","https://openalex.org/W2047548407","https://openalex.org/W2156541195"],"abstract_inverted_index":{"A":[0],"continuum":[1,52,73,86],"multi-domain":[2,91],"model":[3,53,74,87,92,108],"of":[4,7,23,81,112,123],"electrical":[5,67],"stimulation":[6,68],"the":[8,15,43,72,76,82,89,101,110,121],"retina":[9],"is":[10,31,88],"presented.":[11],"Each":[12],"point":[13],"in":[14,42],"retinal":[16],"ganglion":[17],"cell":[18],"layer":[19],"could":[20],"be":[21],"thought":[22],"as":[24,79],"representing":[25],"a":[26,34,57],"single":[27],"cell,":[28],"whose":[29],"biophysics":[30],"described":[32],"using":[33,63],"four-compartment":[35],"formulation":[36],"incorporating":[37],"varying":[38],"ion":[39],"channel":[40],"expressions":[41],"soma,":[44],"axon":[45],"initial":[46],"segment,":[47],"dendrites":[48],"and":[49,65],"axon.":[50],"Our":[51,85],"was":[54],"validated":[55],"against":[56],"discrete":[58,83],"morphologically-realistic":[59],"OFF":[60],"RGC":[61,97],"model,":[62],"intra-":[64],"extra-cellular":[66],"scenarios.":[69],"Simulations":[70],"from":[71],"reproduced":[75],"same":[77],"results":[78],"that":[80,106],"model.":[84],"first":[90],"to":[93,119],"represent":[94],"all":[95],"main":[96],"compartments,":[98],"not":[99],"just":[100],"soma.":[102],"Moreover,":[103],"we":[104],"demonstrated":[105],"this":[107],"allows":[109],"investigation":[111],"axonal":[113],"activation":[114],"which":[115],"has":[116],"been":[117],"observed":[118],"influence":[120],"perception":[122],"phosphenes.":[124]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}