{"id":"https://openalex.org/W2754215411","doi":"https://doi.org/10.1109/embc.2017.8036988","title":"Localizing neuronal somata from Multi-Electrode Array in-vivo recordings using deep learning","display_name":"Localizing neuronal somata from Multi-Electrode Array in-vivo recordings using deep learning","publication_year":2017,"publication_date":"2017-07-01","ids":{"openalex":"https://openalex.org/W2754215411","doi":"https://doi.org/10.1109/embc.2017.8036988","mag":"2754215411","pmid":"https://pubmed.ncbi.nlm.nih.gov/29060036"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2017.8036988","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8036988","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10852/65491","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022611002","display_name":"Alessio Paolo Buccino","orcid":"https://orcid.org/0000-0003-3661-527X"},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Alessio P. Buccino","raw_affiliation_strings":["Department of Informatics, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Informatics, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027042571","display_name":"Torbj\u00f8rn V. Ness","orcid":"https://orcid.org/0000-0001-9080-8502"},"institutions":[{"id":"https://openalex.org/I54108979","display_name":"Norwegian University of Life Sciences","ror":"https://ror.org/04a1mvv97","country_code":"NO","type":"education","lineage":["https://openalex.org/I54108979"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Torbjorn V. Ness","raw_affiliation_strings":["Faculty of Science and Technology, Norwegian University of Life Sciences, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science and Technology, Norwegian University of Life Sciences, Norway","institution_ids":["https://openalex.org/I54108979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032715711","display_name":"Gaute T. Einevoll","orcid":"https://orcid.org/0000-0002-5425-5012"},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]},{"id":"https://openalex.org/I54108979","display_name":"Norwegian University of Life Sciences","ror":"https://ror.org/04a1mvv97","country_code":"NO","type":"education","lineage":["https://openalex.org/I54108979"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Gaute T. Einevoll","raw_affiliation_strings":["Department of Physics, University of Oslo, Oslo, Norway","Faculty of Science and Technology, Norwegian University of Life Sciences, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]},{"raw_affiliation_string":"Faculty of Science and Technology, Norwegian University of Life Sciences, Norway","institution_ids":["https://openalex.org/I54108979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059013717","display_name":"Gert Cauwenberghs","orcid":"https://orcid.org/0000-0002-3166-5529"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210133661","display_name":"La Jolla Bioengineering Institute","ror":"https://ror.org/03sgbh608","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210133661"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gert Cauwenberghs","raw_affiliation_strings":["Department of Bioengineering, University of California San Diego, La Jolla, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of California San Diego, La Jolla, CA, USA","institution_ids":["https://openalex.org/I4210133661","https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002194680","display_name":"Philipp H\u00e4fliger","orcid":"https://orcid.org/0000-0001-5940-9976"},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Philipp D. Hafliger","raw_affiliation_strings":["Department of Informatics, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Informatics, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1956,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.7524556,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"2017","issue":null,"first_page":"974","last_page":"977"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.989799976348877,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7406219840049744},{"id":"https://openalex.org/keywords/neocortex","display_name":"Neocortex","score":0.6405367851257324},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5763510465621948},{"id":"https://openalex.org/keywords/electrode-array","display_name":"Electrode array","score":0.5646588206291199},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5537744164466858},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5368784666061401},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.5002944469451904},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.42979252338409424},{"id":"https://openalex.org/keywords/biological-neural-network","display_name":"Biological neural network","score":0.42656606435775757},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.41460996866226196},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.2657252550125122},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.18466967344284058},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.18062958121299744},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.08128660917282104},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.06627905368804932}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7406219840049744},{"id":"https://openalex.org/C2777222312","wikidata":"https://www.wikidata.org/wiki/Q726562","display_name":"Neocortex","level":2,"score":0.6405367851257324},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5763510465621948},{"id":"https://openalex.org/C97562148","wikidata":"https://www.wikidata.org/wiki/Q5357989","display_name":"Electrode array","level":3,"score":0.5646588206291199},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5537744164466858},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5368784666061401},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.5002944469451904},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.42979252338409424},{"id":"https://openalex.org/C118403218","wikidata":"https://www.wikidata.org/wiki/Q43283","display_name":"Biological neural network","level":2,"score":0.42656606435775757},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.41460996866226196},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.2657252550125122},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.18466967344284058},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.18062958121299744},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08128660917282104},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06627905368804932},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2017.8036988","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2017.8036988","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:29060036","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29060036","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:www.duo.uio.no:10852/65491","is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/65491","pdf_url":null,"source":{"id":"https://openalex.org/S4306401716","display_name":"Duo Research Archive (University of Oslo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I184942183","host_organization_name":"University of Oslo","host_organization_lineage":["https://openalex.org/I184942183"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"1557-170X","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:www.duo.uio.no:10852/65491","is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/65491","pdf_url":null,"source":{"id":"https://openalex.org/S4306401716","display_name":"Duo Research Archive (University of Oslo)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I184942183","host_organization_name":"University of Oslo","host_organization_lineage":["https://openalex.org/I184942183"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"1557-170X","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323260","display_name":"Universitetet i Oslo","ror":"https://ror.org/01xtthb56"},{"id":"https://openalex.org/F4320329713","display_name":"Utdannings- og forskningsdepartementet","ror":null},{"id":"https://openalex.org/F4320332603","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W602834913","https://openalex.org/W1673814912","https://openalex.org/W1921182138","https://openalex.org/W2046425136","https://openalex.org/W2049517674","https://openalex.org/W2141361751","https://openalex.org/W2165586822","https://openalex.org/W2184182456","https://openalex.org/W2204326174","https://openalex.org/W2580058560","https://openalex.org/W2949787383","https://openalex.org/W4214775604"],"related_works":["https://openalex.org/W4310571718","https://openalex.org/W1976698932","https://openalex.org/W4226493464","https://openalex.org/W4312417841","https://openalex.org/W3193565141","https://openalex.org/W3133861977","https://openalex.org/W3167935049","https://openalex.org/W3103566983","https://openalex.org/W3029198973","https://openalex.org/W3119818034"],"abstract_inverted_index":{"With":[0],"the":[1,5,18,22,34,70,74,89,104,114,128,147],"latest":[2],"development":[3],"in":[4,21,39,84],"design":[6],"and":[7,97,109,132,150],"fabrication":[8],"of":[9,29,47,64,73,88],"high-density":[10],"Multi-Electrode":[11],"Arrays":[12],"(MEA)":[13],"for":[14,26,42,120,146],"in-vivo":[15],"neural":[16,43,82,129],"recordings,":[17],"spatiotemporal":[19],"information":[20],"recorded":[23],"signals":[24],"allows":[25],"refined":[27],"estimation":[28],"a":[30,61,121],"neuron's":[31],"location":[32,130],"around":[33],"probe.":[35],"In":[36],"parallel,":[37],"advances":[38],"computational":[40],"models":[41,78],"activity":[44],"enables":[45],"simulation":[46,66],"recordings":[48],"from":[49,79],"neurons":[50],"with":[51,98,101,133,155],"detailed":[52],"morphology.":[53],"Our":[54],"approach":[55,141],"uses":[56],"deep":[57],"learning":[58,140],"algorithms":[59],"on":[60,113],"large":[62],"set":[63],"such":[65],"data":[67],"to":[68,103,153],"extract":[69],"3D":[71],"position":[72],"neuronal":[75],"somata.":[76],"Multi-compartment":[77],"13":[80],"different":[81,99,148,156],"morphologies":[83,149],"layer":[85],"5":[86],"(L5)":[87],"rat's":[90],"neocortex":[91],"are":[92],"placed":[93],"at":[94],"random":[95],"locations":[96],"alignments":[100],"respect":[102],"MEA.":[105],"The":[106,137],"sodium":[107],"trough":[108],"repolarisation":[110],"peak":[111],"images":[112],"MEA":[115],"serve":[116],"as":[117],"input":[118],"features":[119],"Convolutional":[122],"Neural":[123],"Network":[124],"(CNN),":[125],"which":[126],"predicts":[127],"robustly":[131],"low":[134],"error":[135],"rates.":[136],"forward":[138],"modeling/machine":[139],"yields":[142],"very":[143],"accurate":[144],"results":[145],"is":[151],"able":[152],"cope":[154],"neuron":[157],"alignments.":[158]},"counts_by_year":[{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":7}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}