{"id":"https://openalex.org/W2534664812","doi":"https://doi.org/10.1109/embc.2016.7591109","title":"Investigation on the hermeticity of an implantable package with 32 feedthroughs for neural prosthetic applications","display_name":"Investigation on the hermeticity of an implantable package with 32 feedthroughs for neural prosthetic applications","publication_year":2016,"publication_date":"2016-08-01","ids":{"openalex":"https://openalex.org/W2534664812","doi":"https://doi.org/10.1109/embc.2016.7591109","mag":"2534664812","pmid":"https://pubmed.ncbi.nlm.nih.gov/28268714"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2016.7591109","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2016.7591109","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075993036","display_name":"Lorenzo Bisoni","orcid":"https://orcid.org/0000-0002-8820-7668"},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lorenzo Bisoni","raw_affiliation_strings":["Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101571545","display_name":"Matthias Mueller","orcid":"https://orcid.org/0000-0003-2074-144X"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias Mueller","raw_affiliation_strings":["Department of Microsystems Engineering, University of Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microsystems Engineering, University of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057740989","display_name":"Paul \u010cvan\u010dara","orcid":"https://orcid.org/0000-0003-2189-4413"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Paul Cvancara","raw_affiliation_strings":["Department of Microsystems Engineering, University of Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microsystems Engineering, University of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083470266","display_name":"Caterina Carboni","orcid":null},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Caterina Carboni","raw_affiliation_strings":["Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107229320","display_name":"Roberto Puddu","orcid":"https://orcid.org/0000-0003-3246-6940"},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Puddu","raw_affiliation_strings":["Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007761671","display_name":"Luigi Raffo","orcid":"https://orcid.org/0000-0001-9683-009X"},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigi Raffo","raw_affiliation_strings":["Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002078286","display_name":"Massimo Barbaro","orcid":"https://orcid.org/0000-0001-6136-7664"},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Barbaro","raw_affiliation_strings":["Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering - DIEE, University of Cagliari, Italy","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058067206","display_name":"Thomas Stieglitz","orcid":"https://orcid.org/0000-0002-7349-4254"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Stieglitz","raw_affiliation_strings":["Department of Microsystems Engineering, University of Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microsystems Engineering, University of Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3711,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.91313789,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"2016","issue":null,"first_page":"1967","last_page":"1970"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ceramic","display_name":"Ceramic","score":0.523625910282135},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5087581276893616},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.4953376352787018},{"id":"https://openalex.org/keywords/cylinder","display_name":"Cylinder","score":0.48280560970306396},{"id":"https://openalex.org/keywords/soldering","display_name":"Soldering","score":0.41921624541282654},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.41760337352752686},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3672884702682495},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3445918560028076},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.2580845057964325},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.22163060307502747},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.11146995425224304}],"concepts":[{"id":"https://openalex.org/C134132462","wikidata":"https://www.wikidata.org/wiki/Q45621","display_name":"Ceramic","level":2,"score":0.523625910282135},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5087581276893616},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.4953376352787018},{"id":"https://openalex.org/C203311528","wikidata":"https://www.wikidata.org/wiki/Q34132","display_name":"Cylinder","level":2,"score":0.48280560970306396},{"id":"https://openalex.org/C50296614","wikidata":"https://www.wikidata.org/wiki/Q211387","display_name":"Soldering","level":2,"score":0.41921624541282654},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.41760337352752686},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3672884702682495},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3445918560028076},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.2580845057964325},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.22163060307502747},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.11146995425224304}],"mesh":[{"descriptor_ui":"D000537","descriptor_name":"Aluminum Oxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000537","descriptor_name":"Aluminum Oxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000537","descriptor_name":"Aluminum Oxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002516","descriptor_name":"Ceramics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002516","descriptor_name":"Ceramics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002516","descriptor_name":"Ceramics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004349","descriptor_name":"Drug Packaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004349","descriptor_name":"Drug Packaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004349","descriptor_name":"Drug Packaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010984","descriptor_name":"Platinum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010984","descriptor_name":"Platinum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010984","descriptor_name":"Platinum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019736","descriptor_name":"Prostheses and Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2016.7591109","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2016.7591109","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:28268714","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28268714","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:iris.unica.it:11584/374603","is_oa":false,"landing_page_url":"https://hdl.handle.net/11584/374603","pdf_url":null,"source":{"id":"https://openalex.org/S4377196293","display_name":"UNICA IRIS Institutional Research Information System (University of Cagliari)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I172446870","host_organization_name":"University of Cagliari","host_organization_lineage":["https://openalex.org/I172446870"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferencePaper"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5799999833106995,"id":"https://metadata.un.org/sdg/11","display_name":"Sustainable cities and communities"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1539428229","https://openalex.org/W1600858129","https://openalex.org/W1939098316","https://openalex.org/W1964517795","https://openalex.org/W1972657795","https://openalex.org/W1977083402","https://openalex.org/W2004411875","https://openalex.org/W2033305448","https://openalex.org/W2056473587","https://openalex.org/W2306387545","https://openalex.org/W2413096645","https://openalex.org/W2491658130","https://openalex.org/W2491740747","https://openalex.org/W2596852703","https://openalex.org/W4205647783","https://openalex.org/W4240598302","https://openalex.org/W4250110895"],"related_works":["https://openalex.org/W2367566533","https://openalex.org/W2187937315","https://openalex.org/W1983256527","https://openalex.org/W2297830036","https://openalex.org/W2113862045","https://openalex.org/W2384038313","https://openalex.org/W2378851622","https://openalex.org/W2349280512","https://openalex.org/W2358895457","https://openalex.org/W1608412088"],"abstract_inverted_index":{"This":[0],"paper":[1],"presents":[2,57],"an":[3,36,106],"implantable":[4],"package":[5,18],"aimed":[6],"at":[7,62],"hosting":[8],"a":[9,32,43,78,84],"bidirectional":[10],"neural":[11,14],"interface":[12],"for":[13,26,29],"prosthetic":[15],"applications.":[16],"The":[17,51,71,93],"has":[19,48,74,96],"been":[20,49,75,97],"conceived":[21],"to":[22],"minimize":[23],"the":[24,27,63,69,90,109],"invasivity":[25],"patient,":[28],"this":[30],"reason":[31],"cylindrical":[33],"container":[34],"with":[35],"outer":[37],"diameter":[38],"of":[39,45,68,89,102,113,119],"7":[40],"mm":[41,47],"and":[42,65],"length":[44],"21":[46],"designed.":[50],"package,":[52],"realized":[53],"in":[54,108],"alumina":[55],"(Al2O3),":[56],"32":[58],"hermetic":[59,72],"feedthroughs":[60],"located":[61],"top":[64],"bottom":[66],"base":[67],"cylinder.":[70],"housing":[73],"assembled":[76],"using":[77],"low-temperature":[79],"soldering":[80],"method":[81],"based":[82],"on":[83],"previous":[85],"platinum/gold":[86],"(Pt/Au)":[87],"metallization":[88],"ceramic":[91],"parts.":[92],"package's":[94],"hermeticity":[95],"successfully":[98],"proved":[99],"by":[100],"means":[101],"in-vitro":[103],"tests,":[104],"exhibiting":[105],"increase":[107],"inner":[110],"relative":[111],"humidity":[112],"20":[114],"%RH":[115],"over":[116],"75":[117],"days":[118],"observation.":[120]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}