{"id":"https://openalex.org/W2536112813","doi":"https://doi.org/10.1109/embc.2016.7591028","title":"Tunable somatosensory stimulation for selective sleep restriction studies in rodents","display_name":"Tunable somatosensory stimulation for selective sleep restriction studies in rodents","publication_year":2016,"publication_date":"2016-08-01","ids":{"openalex":"https://openalex.org/W2536112813","doi":"https://doi.org/10.1109/embc.2016.7591028","mag":"2536112813","pmid":"https://pubmed.ncbi.nlm.nih.gov/28268644"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2016.7591028","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2016.7591028","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108612785","display_name":"Dillon Huffman","orcid":null},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Dillon M. Huffman","raw_affiliation_strings":["Department of Biomedical Engineering, University of Kentucky"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Kentucky","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056982538","display_name":"Kendra E. Staggs","orcid":null},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kendra E. Staggs","raw_affiliation_strings":["Department of Pharmacology and Nutritional Sciences, University of Kentucky"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Nutritional Sciences, University of Kentucky","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091431299","display_name":"Farid Yaghouby","orcid":"https://orcid.org/0000-0002-5380-2483"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farid Yaghouby","raw_affiliation_strings":["Department of Biomedical Engineering, University of Kentucky"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Kentucky","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010390115","display_name":"Anuj Agarwal","orcid":"https://orcid.org/0000-0003-0149-4295"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anuj Agarwal","raw_affiliation_strings":["Signal Solutions, LLC"],"affiliations":[{"raw_affiliation_string":"Signal Solutions, LLC","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074519062","display_name":"Bruce F. O\u2019Hara","orcid":null},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce F. O'Hara","raw_affiliation_strings":["Department of Biology, University of Kentucky"],"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Kentucky","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014574021","display_name":"Kevin D. Donohue","orcid":"https://orcid.org/0000-0003-4423-6296"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin D. Donohue","raw_affiliation_strings":["Department of Electrical Engineering, University of Kentucky"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, University of Kentucky","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031130745","display_name":"Eric M. Blalock","orcid":"https://orcid.org/0000-0001-7242-9429"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric M. Blalock","raw_affiliation_strings":["Department of Pharmacology and Nutritional Sciences, University of Kentucky"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Nutritional Sciences, University of Kentucky","institution_ids":["https://openalex.org/I143302722"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041765061","display_name":"Sridhar Sunderam","orcid":"https://orcid.org/0000-0002-2457-6157"},"institutions":[{"id":"https://openalex.org/I143302722","display_name":"University of Kentucky","ror":"https://ror.org/02k3smh20","country_code":"US","type":"education","lineage":["https://openalex.org/I143302722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sridhar Sunderam","raw_affiliation_strings":["Department of Biomedical Engineering, University of Kentucky"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Kentucky","institution_ids":["https://openalex.org/I143302722"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5108612785"],"corresponding_institution_ids":["https://openalex.org/I143302722"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.10506889,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"2016","issue":null,"first_page":"1640","last_page":"1643"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sleep-restriction","display_name":"Sleep restriction","score":0.7724094390869141},{"id":"https://openalex.org/keywords/somatosensory-system","display_name":"Somatosensory system","score":0.6620007753372192},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.6418722867965698},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5798726081848145},{"id":"https://openalex.org/keywords/sleep","display_name":"Sleep (system call)","score":0.5751460194587708},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.4244222640991211},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.38467466831207275},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.37328821420669556},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.36305809020996094},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3298838138580322},{"id":"https://openalex.org/keywords/sleep-deprivation","display_name":"Sleep deprivation","score":0.21047046780586243},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"Circadian rhythm","score":0.10912847518920898}],"concepts":[{"id":"https://openalex.org/C2780937657","wikidata":"https://www.wikidata.org/wiki/Q5141192","display_name":"Sleep restriction","level":4,"score":0.7724094390869141},{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.6620007753372192},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6418722867965698},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5798726081848145},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.5751460194587708},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.4244222640991211},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38467466831207275},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.37328821420669556},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.36305809020996094},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3298838138580322},{"id":"https://openalex.org/C2778329153","wikidata":"https://www.wikidata.org/wiki/Q1364801","display_name":"Sleep deprivation","level":3,"score":0.21047046780586243},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.10912847518920898},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012895","descriptor_name":"Sleep, REM","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012895","descriptor_name":"Sleep, REM","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012895","descriptor_name":"Sleep, REM","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014732","descriptor_name":"Vibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014732","descriptor_name":"Vibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014732","descriptor_name":"Vibration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2016.7591028","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2016.7591028","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:28268644","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28268644","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W78723232","https://openalex.org/W1756051613","https://openalex.org/W2004483169","https://openalex.org/W2045616336","https://openalex.org/W2072931836","https://openalex.org/W2079933139","https://openalex.org/W2124040761","https://openalex.org/W2137418393","https://openalex.org/W2286855854","https://openalex.org/W2319421743"],"related_works":["https://openalex.org/W2940368687","https://openalex.org/W3137255421","https://openalex.org/W2075335062","https://openalex.org/W2047455368","https://openalex.org/W2006992161","https://openalex.org/W4254783977","https://openalex.org/W2806733610","https://openalex.org/W2755571677","https://openalex.org/W112280922","https://openalex.org/W2061579395"],"abstract_inverted_index":{"Many":[0],"methods":[1],"for":[2,51],"sleep":[3,25,30,41,71,127,138,144],"restriction":[4,26,139,145],"in":[5,31,40,72,134,140,146],"rodents":[6],"have":[7],"emerged,":[8],"but":[9],"most":[10],"are":[11],"intrusive,":[12],"lack":[13],"fine":[14],"control,":[15],"and":[16,59,85,94,142],"induce":[17],"stress.":[18],"Therefore,":[19],"a":[20,32,48,82,111],"versatile,":[21],"non-intrusive":[22],"means":[23],"of":[24,37,65,96,107],"that":[27,117],"can":[28],"alter":[29],"controlled":[33],"manner":[34],"could":[35],"be":[36],"great":[38],"value":[39],"research.":[42],"In":[43],"previous":[44],"work,":[45],"we":[46],"proposed":[47],"novel":[49],"system":[50,77,109],"closed-loop":[52],"somatosensory":[53],"stimulation":[54,97],"based":[55],"on":[56],"mechanical":[57],"vibration":[58],"applied":[60,98],"it":[61,80],"to":[62,99,115,123],"the":[63,92,100,105],"task":[64],"restricting":[66],"Rapid":[67],"Eye":[68],"Movement":[69],"(REM)":[70],"mice":[73],"[1].":[74],"While":[75],"this":[76,108],"was":[78,81],"effective,":[79],"crude":[83],"prototype":[84],"did":[86],"not":[87],"allow":[88],"precise":[89],"control":[90,120],"over":[91,121],"amplitude":[93],"frequency":[95],"animal.":[101],"This":[102],"paper":[103],"details":[104],"progression":[106],"from":[110],"binary,":[112],"\"all-or-none\"":[113],"version":[114],"one":[116],"allows":[118],"dynamic":[119],"perturbation":[122],"accomplish":[124],"graded,":[125],"state-dependent":[126],"restriction.":[128],"Its":[129],"preliminary":[130],"use":[131],"is":[132],"described":[133],"two":[135],"applications:":[136],"deep":[137],"rats,":[141],"REM":[143],"mice.":[147]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}