{"id":"https://openalex.org/W2295897559","doi":"https://doi.org/10.1109/embc.2015.7320288","title":"From data to the decision: A software architecture to integrate predictive modelling in clinical settings","display_name":"From data to the decision: A software architecture to integrate predictive modelling in clinical settings","publication_year":2015,"publication_date":"2015-08-01","ids":{"openalex":"https://openalex.org/W2295897559","doi":"https://doi.org/10.1109/embc.2015.7320288","mag":"2295897559","pmid":"https://pubmed.ncbi.nlm.nih.gov/26738188"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2015.7320288","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2015.7320288","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089392767","display_name":"Antonio Mart\u00ednez-Millana","orcid":"https://orcid.org/0000-0003-1056-5067"},"institutions":[{"id":"https://openalex.org/I4210166036","display_name":"Instituto de Investigaci\u00f3n Sanitaria La Fe","ror":"https://ror.org/05n7v5997","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210166036"]},{"id":"https://openalex.org/I4210156219","display_name":"Tecnolog\u00edas para la Salud y el Bienestar (Spain)","ror":"https://ror.org/05w0e5x87","country_code":"ES","type":"company","lineage":["https://openalex.org/I4210156219"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"A. Martinez-Millana","raw_affiliation_strings":["Unidad Mixta de Reingenieria de Procesos Sociosanitarios (eRPSS), Instituto de Investigaci6n Sanitaria del Hospital Universitario y Polit\u00e9cnico La Fe, Valencia, Spain","company Tecnologias para la Salud y el Bienestar S.A. Ronda Auguste y Louis Lumiere 23, Paterna, Valencia, Spain"],"affiliations":[{"raw_affiliation_string":"Unidad Mixta de Reingenieria de Procesos Sociosanitarios (eRPSS), Instituto de Investigaci6n Sanitaria del Hospital Universitario y Polit\u00e9cnico La Fe, Valencia, Spain","institution_ids":["https://openalex.org/I4210166036"]},{"raw_affiliation_string":"company Tecnologias para la Salud y el Bienestar S.A. Ronda Auguste y Louis Lumiere 23, Paterna, Valencia, Spain","institution_ids":["https://openalex.org/I4210156219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084945551","display_name":"Carlos Fern\u00e1ndez-Llatas","orcid":"https://orcid.org/0000-0002-2819-5597"},"institutions":[{"id":"https://openalex.org/I60053951","display_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","ror":"https://ror.org/01460j859","country_code":"ES","type":"education","lineage":["https://openalex.org/I60053951"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"C. Fernandez-Llatas","raw_affiliation_strings":["Universitat Politecnica de Valencia, Valencia, Valenciana, ES"],"affiliations":[{"raw_affiliation_string":"Universitat Politecnica de Valencia, Valencia, Valenciana, ES","institution_ids":["https://openalex.org/I60053951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069995691","display_name":"Lucia Sacchi","orcid":"https://orcid.org/0000-0002-1390-9825"},"institutions":[{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"L. Sacchi","raw_affiliation_strings":["Dipartimento di Ingenieria Industriale e de'IlInformazione, Universit\u00e0 degli Studi di Pavia, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Ingenieria Industriale e de'IlInformazione, Universit\u00e0 degli Studi di Pavia, Italy","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038921121","display_name":"Daniele Segagni","orcid":null},"institutions":[{"id":"https://openalex.org/I4210105320","display_name":"Fondazione Salvatore Maugeri","ror":"https://ror.org/01e8tvg28","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210105320","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D. Segagni","raw_affiliation_strings":["Laboratono di Intormatica e Sistemrsttca In Fondazione Salvatore Maugeri IRCCS, Italy"],"affiliations":[{"raw_affiliation_string":"Laboratono di Intormatica e Sistemrsttca In Fondazione Salvatore Maugeri IRCCS, Italy","institution_ids":["https://openalex.org/I4210105320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079800216","display_name":"Sergio Guill\u00e9n","orcid":"https://orcid.org/0000-0002-6692-2185"},"institutions":[{"id":"https://openalex.org/I4210156219","display_name":"Tecnolog\u00edas para la Salud y el Bienestar (Spain)","ror":"https://ror.org/05w0e5x87","country_code":"ES","type":"company","lineage":["https://openalex.org/I4210156219"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"S. Guillen","raw_affiliation_strings":["company Tecnologias para la Salud y el Bienestar S.A. Ronda Auguste y Louis Lumiere 23, Paterna, Valencia, Spain"],"affiliations":[{"raw_affiliation_string":"company Tecnologias para la Salud y el Bienestar S.A. Ronda Auguste y Louis Lumiere 23, Paterna, Valencia, Spain","institution_ids":["https://openalex.org/I4210156219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050932220","display_name":"Riccardo Bellazzi","orcid":"https://orcid.org/0000-0002-6974-9808"},"institutions":[{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R. Bellazzi","raw_affiliation_strings":["Dipartimento di Ingenieria Industriale e de'IlInformazione, Universit\u00e0 degli Studi di Pavia, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Ingenieria Industriale e de'IlInformazione, Universit\u00e0 degli Studi di Pavia, Italy","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075346187","display_name":"Vicente Traver","orcid":"https://orcid.org/0000-0003-1806-8575"},"institutions":[{"id":"https://openalex.org/I4210166036","display_name":"Instituto de Investigaci\u00f3n Sanitaria La Fe","ror":"https://ror.org/05n7v5997","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210166036"]},{"id":"https://openalex.org/I60053951","display_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","ror":"https://ror.org/01460j859","country_code":"ES","type":"education","lineage":["https://openalex.org/I60053951"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"V. Traver","raw_affiliation_strings":["SABIEN-ITACA Institute Universitat Politecnica de Valencia, Valencia, Spain","Unidad Mixta de Reingenieria de Procesos Sociosanitarios (eRPSS), Instituto de Investigaci6n Sanitaria del Hospital Universitario y Polit\u00e9cnico La Fe, Valencia, Spain"],"affiliations":[{"raw_affiliation_string":"SABIEN-ITACA Institute Universitat Politecnica de Valencia, Valencia, Spain","institution_ids":["https://openalex.org/I60053951"]},{"raw_affiliation_string":"Unidad Mixta de Reingenieria de Procesos Sociosanitarios (eRPSS), Instituto de Investigaci6n Sanitaria del Hospital Universitario y Polit\u00e9cnico La Fe, Valencia, Spain","institution_ids":["https://openalex.org/I4210166036"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5089392767"],"corresponding_institution_ids":["https://openalex.org/I4210156219","https://openalex.org/I4210166036"],"apc_list":null,"apc_paid":null,"fwci":1.7446,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.86021106,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"343","issue":null,"first_page":"8161","last_page":"8164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.9901000261306763,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9853000044822693,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7564531564712524},{"id":"https://openalex.org/keywords/component","display_name":"Component (thermodynamics)","score":0.6698030233383179},{"id":"https://openalex.org/keywords/dependency","display_name":"Dependency (UML)","score":0.5963295698165894},{"id":"https://openalex.org/keywords/software-architecture","display_name":"Software architecture","score":0.5261240005493164},{"id":"https://openalex.org/keywords/architecture","display_name":"Architecture","score":0.5173355937004089},{"id":"https://openalex.org/keywords/data-modeling","display_name":"Data modeling","score":0.5166478753089905},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4720112979412079},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.43636542558670044},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4080182909965515},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.3441706597805023},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.32318753004074097}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7564531564712524},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.6698030233383179},{"id":"https://openalex.org/C19768560","wikidata":"https://www.wikidata.org/wiki/Q320727","display_name":"Dependency (UML)","level":2,"score":0.5963295698165894},{"id":"https://openalex.org/C35869016","wikidata":"https://www.wikidata.org/wiki/Q846636","display_name":"Software architecture","level":3,"score":0.5261240005493164},{"id":"https://openalex.org/C123657996","wikidata":"https://www.wikidata.org/wiki/Q12271","display_name":"Architecture","level":2,"score":0.5173355937004089},{"id":"https://openalex.org/C67186912","wikidata":"https://www.wikidata.org/wiki/Q367664","display_name":"Data modeling","level":2,"score":0.5166478753089905},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4720112979412079},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.43636542558670044},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4080182909965515},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.3441706597805023},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32318753004074097},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C153349607","wikidata":"https://www.wikidata.org/wiki/Q36649","display_name":"Visual arts","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001108","descriptor_name":"Architecture","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001108","descriptor_name":"Architecture","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001108","descriptor_name":"Architecture","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008433","descriptor_name":"Mathematics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008433","descriptor_name":"Mathematics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008433","descriptor_name":"Mathematics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2015.7320288","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2015.7320288","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:26738188","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26738188","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5299999713897705,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W30646434","https://openalex.org/W1500263493","https://openalex.org/W1525537510","https://openalex.org/W1594407938","https://openalex.org/W1739460100","https://openalex.org/W2008035769","https://openalex.org/W2020267609","https://openalex.org/W2034512648","https://openalex.org/W2045068495","https://openalex.org/W2055838663","https://openalex.org/W2082376914","https://openalex.org/W2083341430","https://openalex.org/W2101359494","https://openalex.org/W2101508556","https://openalex.org/W2119910794","https://openalex.org/W2124704085","https://openalex.org/W2125733695","https://openalex.org/W2129925362","https://openalex.org/W2153509994","https://openalex.org/W2271491336","https://openalex.org/W6635488347"],"related_works":["https://openalex.org/W2067317451","https://openalex.org/W2357256365","https://openalex.org/W2154771632","https://openalex.org/W4211085505","https://openalex.org/W2348502264","https://openalex.org/W3122478268","https://openalex.org/W2084758217","https://openalex.org/W2365486383","https://openalex.org/W408804804","https://openalex.org/W2171641484"],"abstract_inverted_index":{"The":[0],"application":[1],"of":[2,9,63,96,117],"statistics":[3],"and":[4,20,30,57,105],"mathematics":[5],"over":[6],"large":[7],"amounts":[8],"data":[10,77,82,102],"is":[11],"providing":[12,51,121],"healthcare":[13],"systems":[14],"with":[15,39],"new":[16],"tools":[17,26],"for":[18,55,125],"screening":[19,62],"managing":[21],"multiple":[22],"diseases.":[23],"Nonetheless,":[24],"these":[25],"have":[27],"many":[28],"technical":[29],"clinical":[31,133],"limitations":[32],"as":[33,128],"they":[34,129],"are":[35,130],"based":[36],"on":[37,50],"datasets":[38],"concrete":[40],"characteristics.":[41],"This":[42,109],"proposition":[43],"paper":[44],"describes":[45],"a":[46,52,80,90,122],"novel":[47],"architecture":[48,70],"focused":[49],"validation":[53,123],"framework":[54,124],"discrimination":[56],"prediction":[58],"models":[59,104,119,127],"in":[60,94],"the":[61,69,98,115,118,126],"Type":[64],"2":[65],"diabetes.":[66],"For":[67],"that,":[68],"has":[71],"been":[72],"designed":[73],"to":[74,86,113],"gather":[75],"different":[76],"sources":[78],"under":[79],"common":[81],"structure":[83],"and,":[84],"furthermore,":[85],"be":[87],"controlled":[88],"by":[89,120],"centralized":[91],"component":[92],"(Orchestrator)":[93],"charge":[95],"directing":[97],"interaction":[99],"flows":[100],"among":[101],"sources,":[103],"graphical":[106],"user":[107],"interfaces.":[108],"innovative":[110],"approach":[111],"aims":[112],"overcome":[114],"data-dependency":[116],"used":[131],"within":[132],"settings.":[134]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}