{"id":"https://openalex.org/W2323275464","doi":"https://doi.org/10.1109/embc.2015.7319713","title":"Design of site-directed magnetic targeting system in acute spinal cord injury","display_name":"Design of site-directed magnetic targeting system in acute spinal cord injury","publication_year":2015,"publication_date":"2015-08-01","ids":{"openalex":"https://openalex.org/W2323275464","doi":"https://doi.org/10.1109/embc.2015.7319713","mag":"2323275464","pmid":"https://pubmed.ncbi.nlm.nih.gov/26737613"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2015.7319713","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2015.7319713","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084495272","display_name":"Guang-Hao Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guang-Hao Zhang","raw_affiliation_strings":["Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100449554","display_name":"Aihua Wang","orcid":"https://orcid.org/0000-0003-4675-6746"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ai-Hua Wang","raw_affiliation_strings":["Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107171363","display_name":"Cheng Zhang","orcid":"https://orcid.org/0000-0002-8948-4093"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cheng Zhang","raw_affiliation_strings":["Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112369265","display_name":"Changzhe Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chang-Zhe Wu","raw_affiliation_strings":["Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103254950","display_name":"Lili Hu","orcid":"https://orcid.org/0000-0002-2758-7935"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li-Li Hu","raw_affiliation_strings":["Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086830713","display_name":"Xiaolin Huo","orcid":"https://orcid.org/0000-0001-7416-3601"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Lin Huo","raw_affiliation_strings":["Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Bioelectromagnetism, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing, Beijing, CN","institution_ids":["https://openalex.org/I19820366"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I19820366"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.28820375,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"3","issue":null,"first_page":"5813","last_page":"5816"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12405","display_name":"Characterization and Applications of Magnetic Nanoparticles","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12405","display_name":"Characterization and Applications of Magnetic Nanoparticles","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10090","display_name":"ZnO doping and properties","score":0.9901000261306763,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9822999835014343,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnetic-field","display_name":"Magnetic field","score":0.5963126420974731},{"id":"https://openalex.org/keywords/magnet","display_name":"Magnet","score":0.5943065881729126},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5939561128616333},{"id":"https://openalex.org/keywords/magnetic-nanoparticles","display_name":"Magnetic nanoparticles","score":0.5812692046165466},{"id":"https://openalex.org/keywords/ferromagnetism","display_name":"Ferromagnetism","score":0.5219992399215698},{"id":"https://openalex.org/keywords/spinal-cord","display_name":"Spinal cord","score":0.5112040042877197},{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"Spinal cord injury","score":0.47565099596977234},{"id":"https://openalex.org/keywords/nanomaterials","display_name":"Nanomaterials","score":0.4409118890762329},{"id":"https://openalex.org/keywords/membrane","display_name":"Membrane","score":0.4342457354068756},{"id":"https://openalex.org/keywords/nuclear-magnetic-resonance","display_name":"Nuclear magnetic resonance","score":0.38814571499824524},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.37831687927246094},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.34993594884872437},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.2827163338661194},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.16374805569648743},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.16124877333641052},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.15410777926445007},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.12312602996826172},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.12245053052902222},{"id":"https://openalex.org/keywords/condensed-matter-physics","display_name":"Condensed matter physics","score":0.07946911454200745}],"concepts":[{"id":"https://openalex.org/C115260700","wikidata":"https://www.wikidata.org/wiki/Q11408","display_name":"Magnetic field","level":2,"score":0.5963126420974731},{"id":"https://openalex.org/C16389437","wikidata":"https://www.wikidata.org/wiki/Q11421","display_name":"Magnet","level":2,"score":0.5943065881729126},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5939561128616333},{"id":"https://openalex.org/C87023908","wikidata":"https://www.wikidata.org/wiki/Q3870166","display_name":"Magnetic nanoparticles","level":3,"score":0.5812692046165466},{"id":"https://openalex.org/C82217956","wikidata":"https://www.wikidata.org/wiki/Q184207","display_name":"Ferromagnetism","level":2,"score":0.5219992399215698},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.5112040042877197},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.47565099596977234},{"id":"https://openalex.org/C138631740","wikidata":"https://www.wikidata.org/wiki/Q967847","display_name":"Nanomaterials","level":2,"score":0.4409118890762329},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.4342457354068756},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.38814571499824524},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.37831687927246094},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.34993594884872437},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.2827163338661194},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16374805569648743},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.16124877333641052},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15410777926445007},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.12312602996826172},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12245053052902222},{"id":"https://openalex.org/C26873012","wikidata":"https://www.wikidata.org/wiki/Q214781","display_name":"Condensed matter physics","level":1,"score":0.07946911454200745},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007267","descriptor_name":"Injections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007267","descriptor_name":"Injections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007267","descriptor_name":"Injections","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009339","descriptor_name":"Needles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009339","descriptor_name":"Needles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009339","descriptor_name":"Needles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013119","descriptor_name":"Spinal Cord Injuries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059346","descriptor_name":"Magnets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059346","descriptor_name":"Magnets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059346","descriptor_name":"Magnets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2015.7319713","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2015.7319713","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:26737613","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26737613","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1872514626","https://openalex.org/W1975514668","https://openalex.org/W1996328426","https://openalex.org/W2011385473","https://openalex.org/W2019736713","https://openalex.org/W2030351723","https://openalex.org/W2035433475","https://openalex.org/W2038159444","https://openalex.org/W2043449909","https://openalex.org/W2057786671","https://openalex.org/W2062071298","https://openalex.org/W2107435825","https://openalex.org/W2133177228","https://openalex.org/W2163283722","https://openalex.org/W2366227620"],"related_works":["https://openalex.org/W2111961950","https://openalex.org/W2379540828","https://openalex.org/W3092790976","https://openalex.org/W1498130003","https://openalex.org/W2020823953","https://openalex.org/W2603023637","https://openalex.org/W2550842661","https://openalex.org/W2357660565","https://openalex.org/W2383702835","https://openalex.org/W2381426581"],"abstract_inverted_index":{"Effective":[0],"repair":[1,27,39],"immediately":[2],"after":[3],"spinal":[4,161],"cord":[5,162],"injury":[6,42,158],"can":[7,47,143],"improve":[8,33],"the":[9,12,22,28,34,84,87,92,103,108,114,121,124,130,156,177],"prognosis":[10],"of":[11,15,21,37,86,89,116,126,173],"patient.":[13],"Injection":[14],"membrane":[16,38,44],"resealing":[17,45],"nanomaterial":[18,46],"is":[19,180],"one":[20],"most":[23],"promising":[24],"technique":[25],"to":[26,32,82,95,101],"membrane.":[29],"In":[30,57],"order":[31],"retention":[35],"rate":[36],"material":[40],"at":[41,107,129,155],"site,":[43],"be":[48],"combined":[49],"with":[50,134,140],"magnetic":[51,54,64,93,97,104,127,146],"nanoparticle":[52],"and":[53,73,123,171],"targeting":[55,65,178],"system.":[56],"this":[58],"paper,":[59],"a":[60,69,74,167],"special":[61],"site":[62,159],"directed":[63],"system,":[66],"which":[67],"contain":[68],"C-shaped":[70],"permanent":[71],"magnet":[72],"ferromagnetic":[75,117,174],"needle,":[76],"was":[77,80],"constructed.":[78],"Simulation":[79],"conducted":[81],"analyze":[83],"influence":[85],"shape":[88],"needle":[90,118],"on":[91],"field":[94,128],"provide":[96,166],"force":[98],"large":[99],"enough":[100],"make":[102],"particles":[105],"stay":[106],"target":[109,131],"site.":[110,132],"Results":[111],"showed":[112],"that":[113],"appearance":[115],"raised":[119],"both":[120],"strength":[122],"gradient":[125],"Moreover,":[133],"similar":[135],"apex":[136],"angles,":[137],"longer":[138],"needles":[139,150,175],"larger":[141],"diameters":[142],"produced":[144],"lager":[145],"field,":[147],"but":[148],"smaller":[149],"has":[151],"better":[152],"focal":[153],"area":[154],"small":[157],"in":[160,182],"injury.":[163],"These":[164],"results":[165],"basis":[168],"for":[169],"design":[170],"fabrication":[172],"when":[176],"system":[179],"applied":[181],"future":[183],"experiments.":[184]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2016-06-24T00:00:00"}