{"id":"https://openalex.org/W2295114537","doi":"https://doi.org/10.1109/embc.2015.7319679","title":"Analytical description of the slope of the APD-restitution curve to assess the interacting contribution of conduction and repolarization dynamics","display_name":"Analytical description of the slope of the APD-restitution curve to assess the interacting contribution of conduction and repolarization dynamics","publication_year":2015,"publication_date":"2015-08-01","ids":{"openalex":"https://openalex.org/W2295114537","doi":"https://doi.org/10.1109/embc.2015.7319679","mag":"2295114537","pmid":"https://pubmed.ncbi.nlm.nih.gov/26737579"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2015.7319679","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2015.7319679","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082855807","display_name":"Michele Orini","orcid":"https://orcid.org/0000-0001-5773-0344"},"institutions":[{"id":"https://openalex.org/I2801259928","display_name":"Royal London Hospital","ror":"https://ror.org/019my5047","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044","https://openalex.org/I2801259928"]},{"id":"https://openalex.org/I4210119772","display_name":"University College Hospital at Westmoreland Street","ror":"https://ror.org/02pkrn365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210119772"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michele Orini","raw_affiliation_strings":["Heart Hospital, University College London Hospitals, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Hospital, University College London Hospitals, London, UK","institution_ids":["https://openalex.org/I2801259928","https://openalex.org/I4210119772","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008694213","display_name":"Peter Taggart","orcid":"https://orcid.org/0000-0001-8861-9227"},"institutions":[{"id":"https://openalex.org/I2801259928","display_name":"Royal London Hospital","ror":"https://ror.org/019my5047","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044","https://openalex.org/I2801259928"]},{"id":"https://openalex.org/I4210119772","display_name":"University College Hospital at Westmoreland Street","ror":"https://ror.org/02pkrn365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210119772"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter Taggart","raw_affiliation_strings":["Heart Hospital, University College London Hospitals, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Hospital, University College London Hospitals, London, UK","institution_ids":["https://openalex.org/I2801259928","https://openalex.org/I4210119772","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111458215","display_name":"Martin Hayward","orcid":null},"institutions":[{"id":"https://openalex.org/I2801259928","display_name":"Royal London Hospital","ror":"https://ror.org/019my5047","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044","https://openalex.org/I2801259928"]},{"id":"https://openalex.org/I4210119772","display_name":"University College Hospital at Westmoreland Street","ror":"https://ror.org/02pkrn365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210119772"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Martin Hayward","raw_affiliation_strings":["Heart Hospital, University College London Hospitals, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Hospital, University College London Hospitals, UK","institution_ids":["https://openalex.org/I2801259928","https://openalex.org/I4210119772","https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024316919","display_name":"Pier D. Lambiase","orcid":"https://orcid.org/0000-0002-9055-9267"},"institutions":[{"id":"https://openalex.org/I2801259928","display_name":"Royal London Hospital","ror":"https://ror.org/019my5047","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044","https://openalex.org/I2801259928"]},{"id":"https://openalex.org/I4210119772","display_name":"University College Hospital at Westmoreland Street","ror":"https://ror.org/02pkrn365","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1340918713","https://openalex.org/I4210119772"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pier D. Lambiase","raw_affiliation_strings":["Heart Hospital, University College London Hospitals, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Hospital, University College London Hospitals, London, UK","institution_ids":["https://openalex.org/I2801259928","https://openalex.org/I4210119772","https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.414,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.80057526,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2015","issue":null,"first_page":"5672","last_page":"5675"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.9908999800682068,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9842000007629395,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/restitution","display_name":"Restitution","score":0.6507930755615234},{"id":"https://openalex.org/keywords/repolarization","display_name":"Repolarization","score":0.5676061511039734},{"id":"https://openalex.org/keywords/curve-fitting","display_name":"Curve fitting","score":0.5016605854034424},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.4914666414260864},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.470303475856781},{"id":"https://openalex.org/keywords/thermal-conduction","display_name":"Thermal conduction","score":0.45114678144454956},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.4471118450164795},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4342740774154663},{"id":"https://openalex.org/keywords/relaxation","display_name":"Relaxation (psychology)","score":0.43056559562683105},{"id":"https://openalex.org/keywords/time-constant","display_name":"Time constant","score":0.4121791422367096},{"id":"https://openalex.org/keywords/mechanics","display_name":"Mechanics","score":0.3826955556869507},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.359849750995636},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.21030789613723755},{"id":"https://openalex.org/keywords/electrophysiology","display_name":"Electrophysiology","score":0.1850784420967102},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1801947057247162},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.15332382917404175},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.14462929964065552},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.12578845024108887},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.10770303010940552}],"concepts":[{"id":"https://openalex.org/C2778392301","wikidata":"https://www.wikidata.org/wiki/Q1156800","display_name":"Restitution","level":2,"score":0.6507930755615234},{"id":"https://openalex.org/C146403970","wikidata":"https://www.wikidata.org/wiki/Q205729","display_name":"Repolarization","level":3,"score":0.5676061511039734},{"id":"https://openalex.org/C184389593","wikidata":"https://www.wikidata.org/wiki/Q603159","display_name":"Curve fitting","level":2,"score":0.5016605854034424},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.4914666414260864},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.470303475856781},{"id":"https://openalex.org/C172100665","wikidata":"https://www.wikidata.org/wiki/Q7465774","display_name":"Thermal conduction","level":2,"score":0.45114678144454956},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.4471118450164795},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4342740774154663},{"id":"https://openalex.org/C2776029896","wikidata":"https://www.wikidata.org/wiki/Q3935810","display_name":"Relaxation (psychology)","level":2,"score":0.43056559562683105},{"id":"https://openalex.org/C81370116","wikidata":"https://www.wikidata.org/wiki/Q1335249","display_name":"Time constant","level":2,"score":0.4121791422367096},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.3826955556869507},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.359849750995636},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.21030789613723755},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.1850784420967102},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1801947057247162},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.15332382917404175},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14462929964065552},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.12578845024108887},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10770303010940552},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2015.7319679","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2015.7319679","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:26737579","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26737579","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1479223","is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1479223/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) pp. 5672-5675. (2015)","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1697850052","https://openalex.org/W1974396072","https://openalex.org/W1994666309","https://openalex.org/W2002835602","https://openalex.org/W2037462241","https://openalex.org/W2051502336","https://openalex.org/W2057978401","https://openalex.org/W2087169920","https://openalex.org/W2105896123","https://openalex.org/W2107018539","https://openalex.org/W2131035744","https://openalex.org/W2134638952","https://openalex.org/W2153855760","https://openalex.org/W2163071496","https://openalex.org/W3105710497","https://openalex.org/W6679661564"],"related_works":["https://openalex.org/W2332743925","https://openalex.org/W3151666417","https://openalex.org/W4237717824","https://openalex.org/W2995498550","https://openalex.org/W2337106664","https://openalex.org/W3198455544","https://openalex.org/W4254319424","https://openalex.org/W4391075167","https://openalex.org/W4244549329","https://openalex.org/W85092510"],"abstract_inverted_index":{"The":[0,111,209],"restitution":[1,143,216],"of":[2,52,82,85,96,99,113,125,128,139,149,194,197,221,224],"the":[3,46,50,53,83,86,94,97,100,104,122,126,129,137,140,147,150,157,165,171,174,195,198,218,222,225],"action":[4],"potential":[5],"duration":[6],"(APDR)":[7],"is":[8,37,62,88,217],"a":[9,33,183],"mechanism":[10],"whereby":[11],"cardiac":[12],"excitation":[13],"and":[14,28,201],"relaxation":[15],"adapt":[16],"to":[17,42,56,64,153,162],"changes":[18],"in":[19,136,167,173,182],"heart":[20,187],"rate.":[21],"Several":[22],"studies,":[23],"mainly":[24],"carried":[25],"out":[26],"in-vitro":[27],"in-silico,":[29],"have":[30,71],"demonstrated":[31],"that":[32,48,117,213],"steep":[34],"APDR":[35,54,61,87,101,130,151,158,199,226],"curve":[36,55,102,200],"associated":[38],"with":[39,66],"increased":[40],"vulnerability":[41],"fatal":[43],"arrhythmias.":[44],"However,":[45],"mechanisms":[47],"link":[49],"steepness":[51,138,148],"arrhythmogenesis":[57],"remain":[58],"undetermined.":[59],"Although":[60],"known":[63],"interact":[65],"conduction":[67,108,118],"dynamics,":[68],"few":[69],"studies":[70],"focused":[72],"on":[73,103],"these":[74],"interactions.":[75],"In":[76],"this":[77,114],"paper,":[78],"an":[79],"analytical":[80,203],"expression":[81,91,115],"slope":[84,98,127,144,152,159,196,223],"derived.":[89],"This":[90],"explicitly":[92],"describes":[93],"dependency":[95],"activation":[105,141,168,214],"time":[106,142,169,215],"and/or":[107],"velocity":[109],"changes.":[110],"study":[112],"shows":[116,189],"dynamics":[119],"are":[120],"among":[121],"main":[123,219],"determinants":[124],"curve.":[131,227],"A":[132],"small":[133],"absolute":[134],"increment":[135],"can":[145],"cause":[146],"dramatically":[154],"increase.":[155],"Theoretically,":[156],"quickly":[160],"diverges":[161],"infinity":[163],"when":[164],"increase":[166],"matches":[170],"decrease":[172],"pacing":[175],"interval.":[176],"High":[177],"density":[178],"epicardial":[179],"mapping":[180],"performed":[181],"patient":[184],"undergoing":[185],"open":[186],"surgery,":[188],"excellent":[190],"agreement":[191],"between":[192],"measures":[193],"its":[202],"prediction":[204],"(linear":[205],"correlation":[206],">":[207],"0.95).":[208],"in-vivo":[210],"recordings":[211],"suggest":[212],"determinant":[220]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}