{"id":"https://openalex.org/W2317958832","doi":"https://doi.org/10.1109/embc.2014.6944810","title":"Miniaturized tool for optogenetics based on an LED and an optical fiber interfaced by a silicon housing","display_name":"Miniaturized tool for optogenetics based on an LED and an optical fiber interfaced by a silicon housing","publication_year":2014,"publication_date":"2014-08-01","ids":{"openalex":"https://openalex.org/W2317958832","doi":"https://doi.org/10.1109/embc.2014.6944810","mag":"2317958832","pmid":"https://pubmed.ncbi.nlm.nih.gov/25571178"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2014.6944810","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6944810","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001477974","display_name":"Michael Schwaerzle","orcid":"https://orcid.org/0000-0001-5699-9229"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. Schwaerzle","raw_affiliation_strings":["Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061304413","display_name":"Philipp Elmlinger","orcid":null},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P. Elmlinger","raw_affiliation_strings":["Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041040505","display_name":"Oliver Paul","orcid":"https://orcid.org/0000-0002-2371-7448"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"O. Paul","raw_affiliation_strings":["Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060525702","display_name":"Patrick Ruther","orcid":"https://orcid.org/0000-0002-7358-003X"},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"P. Ruther","raw_affiliation_strings":["Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microsystems Engineering (IMTEK), Albert-Ludwigs-University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I161046081"],"apc_list":null,"apc_paid":null,"fwci":11.0263,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.99326146,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"2014","issue":null,"first_page":"5252","last_page":"5255"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.7489215731620789},{"id":"https://openalex.org/keywords/optical-fiber","display_name":"Optical fiber","score":0.6015016436576843},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.5765745639801025},{"id":"https://openalex.org/keywords/fiber","display_name":"Fiber","score":0.5079014897346497},{"id":"https://openalex.org/keywords/silicon","display_name":"Silicon","score":0.47372546792030334},{"id":"https://openalex.org/keywords/ribbon","display_name":"Ribbon","score":0.46167421340942383},{"id":"https://openalex.org/keywords/microsystem","display_name":"Microsystem","score":0.4517865777015686},{"id":"https://openalex.org/keywords/optogenetics","display_name":"Optogenetics","score":0.44575241208076477},{"id":"https://openalex.org/keywords/chip","display_name":"Chip","score":0.43790048360824585},{"id":"https://openalex.org/keywords/fabrication","display_name":"Fabrication","score":0.4371926486492157},{"id":"https://openalex.org/keywords/multi-mode-optical-fiber","display_name":"Multi-mode optical fiber","score":0.4286348521709442},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.35726198554039},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.3004418611526489},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.16188213229179382},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.13464507460594177},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.09992656111717224}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7489215731620789},{"id":"https://openalex.org/C194232370","wikidata":"https://www.wikidata.org/wiki/Q162","display_name":"Optical fiber","level":2,"score":0.6015016436576843},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.5765745639801025},{"id":"https://openalex.org/C519885992","wikidata":"https://www.wikidata.org/wiki/Q161","display_name":"Fiber","level":2,"score":0.5079014897346497},{"id":"https://openalex.org/C544956773","wikidata":"https://www.wikidata.org/wiki/Q670","display_name":"Silicon","level":2,"score":0.47372546792030334},{"id":"https://openalex.org/C2780392137","wikidata":"https://www.wikidata.org/wiki/Q17121801","display_name":"Ribbon","level":2,"score":0.46167421340942383},{"id":"https://openalex.org/C151054161","wikidata":"https://www.wikidata.org/wiki/Q379385","display_name":"Microsystem","level":2,"score":0.4517865777015686},{"id":"https://openalex.org/C50738837","wikidata":"https://www.wikidata.org/wiki/Q781492","display_name":"Optogenetics","level":2,"score":0.44575241208076477},{"id":"https://openalex.org/C165005293","wikidata":"https://www.wikidata.org/wiki/Q1074500","display_name":"Chip","level":2,"score":0.43790048360824585},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.4371926486492157},{"id":"https://openalex.org/C101645829","wikidata":"https://www.wikidata.org/wiki/Q1781857","display_name":"Multi-mode optical fiber","level":3,"score":0.4286348521709442},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.35726198554039},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.3004418611526489},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.16188213229179382},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.13464507460594177},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.09992656111717224},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004560","descriptor_name":"Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004560","descriptor_name":"Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004560","descriptor_name":"Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008904","descriptor_name":"Miniaturization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008904","descriptor_name":"Miniaturization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008904","descriptor_name":"Miniaturization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D012825","descriptor_name":"Silicon","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012825","descriptor_name":"Silicon","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012825","descriptor_name":"Silicon","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D055100","descriptor_name":"Optical Fibers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055100","descriptor_name":"Optical Fibers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055100","descriptor_name":"Optical Fibers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062308","descriptor_name":"Optogenetics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D062308","descriptor_name":"Optogenetics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D062308","descriptor_name":"Optogenetics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2014.6944810","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6944810","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:25571178","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25571178","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Sustainable cities and communities","score":0.44999998807907104,"id":"https://metadata.un.org/sdg/11"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W110349049","https://openalex.org/W1483977552","https://openalex.org/W1945241997","https://openalex.org/W1964617104","https://openalex.org/W1969812638","https://openalex.org/W2050932531","https://openalex.org/W2089610863","https://openalex.org/W2090973443","https://openalex.org/W2121570266","https://openalex.org/W2127488573","https://openalex.org/W2133677247","https://openalex.org/W2146199250","https://openalex.org/W2497350064"],"related_works":["https://openalex.org/W4206570293","https://openalex.org/W3169838070","https://openalex.org/W3121604985","https://openalex.org/W3155801447","https://openalex.org/W1995267282","https://openalex.org/W2096235556","https://openalex.org/W4234016227","https://openalex.org/W2109867632","https://openalex.org/W2952426443","https://openalex.org/W4243806211"],"abstract_inverted_index":{"This":[0],"paper":[1],"reports":[2],"on":[3,17],"the":[4,29,51,62,86,96,101,110,123,128,138,147],"design,":[5],"simulation,":[6],"fabrication":[7],"and":[8,31,46,68,163],"characterization":[9],"of":[10,43,50,116,151,160,167],"a":[11,18,39,54,104,114,157,164],"tool":[12],"for":[13],"optogenetic":[14],"experiments":[15],"based":[16],"light":[19,126],"emitting":[20],"diode":[21],"(LED).":[22],"A":[23,77],"minimized":[24],"silicon":[25],"(Si)":[26],"interface":[27],"houses":[28],"LED":[30,52,81,102,125],"aligns":[32],"it":[33],"to":[34,95,127],"an":[35,47],"optical":[36,111,132,143],"fiber.":[37],"With":[38],"Si":[40,69,90,139],"housing":[41,91,140],"size":[42],"550\u00d7500\u00d7380":[44],"\u03bcm(3)":[45,79],"electrical":[48],"interconnection":[49],"by":[53],"highly":[55],"flexible":[56],"polyimide":[57],"(PI)":[58],"ribbon":[59],"cable":[60],"is":[61,83,92,134],"system":[63],"very":[64],"variable.":[65],"PI":[66,87,97],"cables":[67],"housings":[70],"are":[71],"fabricated":[72],"using":[73],"established":[74],"microsystem":[75],"technologies.":[76],"270\u00d7220\u00d750":[78],"bare":[80],"chip":[82],"flip-chip-bonded":[84],"onto":[85],"cable.":[88],"The":[89,131],"adhesively":[93,135],"attached":[94],"cable,":[98],"thereby":[99],"hosting":[100],"in":[103],"recess.":[105,141],"An":[106,119,142],"opposite":[107],"recess":[108],"guides":[109],"fiber":[112,129,133,148],"with":[113],"diameter":[115],"125":[117],"\u03bcm.":[118],"aperture":[120],"in-between":[121],"restricts":[122],"emitted":[124],"core.":[130],"fixed":[136],"into":[137],"output":[144],"intensity":[145],"at":[146,156],"end":[149],"facet":[150],"1.71":[152],"mW/mm(2)":[153],"was":[154],"achieved":[155],"duty":[158],"cycle":[159],"10":[161],"%":[162],"driving":[165],"current":[166],"30":[168],"mA.":[169]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}