{"id":"https://openalex.org/W2023397113","doi":"https://doi.org/10.1109/embc.2014.6944354","title":"The Impact of Cervical Manipulation on Heart Rate Variability","display_name":"The Impact of Cervical Manipulation on Heart Rate Variability","publication_year":2014,"publication_date":"2014-08-01","ids":{"openalex":"https://openalex.org/W2023397113","doi":"https://doi.org/10.1109/embc.2014.6944354","mag":"2023397113","pmid":"https://pubmed.ncbi.nlm.nih.gov/25570722"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2014.6944354","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6944354","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079371899","display_name":"Hasan Shafiq","orcid":null},"institutions":[{"id":"https://openalex.org/I39470171","display_name":"Ontario Tech University","ror":"https://ror.org/016zre027","country_code":"CA","type":"education","lineage":["https://openalex.org/I39470171"]},{"id":"https://openalex.org/I4210120717","display_name":"Faculty of Public Health","ror":"https://ror.org/01zqv1s26","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210120717"]}],"countries":["CA","GB"],"is_corresponding":false,"raw_author_name":"Hasan Shafiq","raw_affiliation_strings":["Faculty of Health Sciences","Faculty of Health Sciences, University of Ontario Institute of Technology, 2000 Simcoe St N, Oshawa, ON, L1H 7K4, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences","institution_ids":["https://openalex.org/I4210120717"]},{"raw_affiliation_string":"Faculty of Health Sciences, University of Ontario Institute of Technology, 2000 Simcoe St N, Oshawa, ON, L1H 7K4, Canada","institution_ids":["https://openalex.org/I39470171"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056958802","display_name":"Carolyn McGregor","orcid":"https://orcid.org/0000-0002-0491-4403"},"institutions":[{"id":"https://openalex.org/I39470171","display_name":"Ontario Tech University","ror":"https://ror.org/016zre027","country_code":"CA","type":"education","lineage":["https://openalex.org/I39470171"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Carolyn McGregor","raw_affiliation_strings":["Faculty of Business and Information Technology/Health Sciences","Faculty of Business and Information Technology/ Health Sciences, University of Ontario Institute of Technology, 2000 Simcoe St. N., Oshawa, ON, L1H 7K4 Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Business and Information Technology/Health Sciences","institution_ids":[]},{"raw_affiliation_string":"Faculty of Business and Information Technology/ Health Sciences, University of Ontario Institute of Technology, 2000 Simcoe St. N., Oshawa, ON, L1H 7K4 Canada","institution_ids":["https://openalex.org/I39470171"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022706416","display_name":"Bernadette Murphy","orcid":"https://orcid.org/0000-0001-9832-5740"},"institutions":[{"id":"https://openalex.org/I39470171","display_name":"Ontario Tech University","ror":"https://ror.org/016zre027","country_code":"CA","type":"education","lineage":["https://openalex.org/I39470171"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Bernadette Murphy","raw_affiliation_strings":["Faculty of Health Sciences, University of Ontario Institute of Technology, Oshawa, ON, Canada","Faculty of Health Sciences, University of Ontario Institute of Technology, 2000 Simcoe St N, Oshawa, ON, L1H 7K4, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Ontario Institute of Technology, Oshawa, ON, Canada","institution_ids":["https://openalex.org/I39470171"]},{"raw_affiliation_string":"Faculty of Health Sciences, University of Ontario Institute of Technology, 2000 Simcoe St N, Oshawa, ON, L1H 7K4, Canada","institution_ids":["https://openalex.org/I39470171"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7471,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.79233227,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"2014","issue":null,"first_page":"3406","last_page":"3409"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"Heart rate variability","score":0.8965046405792236},{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"Autonomic nervous system","score":0.7168704271316528},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.6787797808647156},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5782216787338257},{"id":"https://openalex.org/keywords/electrocardiography","display_name":"Electrocardiography","score":0.5722809433937073},{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"Sympathetic nervous system","score":0.5350723266601562},{"id":"https://openalex.org/keywords/balance","display_name":"Balance (ability)","score":0.49790143966674805},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.4911067485809326},{"id":"https://openalex.org/keywords/physical-therapy","display_name":"Physical therapy","score":0.48356005549430847},{"id":"https://openalex.org/keywords/subclinical-infection","display_name":"Subclinical infection","score":0.4237730801105499},{"id":"https://openalex.org/keywords/heart-beat","display_name":"Heart beat","score":0.4201411306858063},{"id":"https://openalex.org/keywords/neck-pain","display_name":"Neck pain","score":0.4109598994255066},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.3899366855621338},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.33495625853538513},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2810376286506653},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.1320883333683014}],"concepts":[{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.8965046405792236},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.7168704271316528},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.6787797808647156},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5782216787338257},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.5722809433937073},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.5350723266601562},{"id":"https://openalex.org/C168031717","wikidata":"https://www.wikidata.org/wiki/Q1530280","display_name":"Balance (ability)","level":2,"score":0.49790143966674805},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4911067485809326},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.48356005549430847},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.4237730801105499},{"id":"https://openalex.org/C2982892191","wikidata":"https://www.wikidata.org/wiki/Q253408","display_name":"Heart beat","level":2,"score":0.4201411306858063},{"id":"https://openalex.org/C2781038967","wikidata":"https://www.wikidata.org/wiki/Q3567802","display_name":"Neck pain","level":3,"score":0.4109598994255066},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3899366855621338},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.33495625853538513},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2810376286506653},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.1320883333683014},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019416","descriptor_name":"Head Movements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019416","descriptor_name":"Head Movements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019416","descriptor_name":"Head Movements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019547","descriptor_name":"Neck Pain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D019547","descriptor_name":"Neck Pain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D019547","descriptor_name":"Neck Pain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020393","descriptor_name":"Manipulation, Spinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020393","descriptor_name":"Manipulation, Spinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020393","descriptor_name":"Manipulation, Spinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2014.6944354","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6944354","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:25570722","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25570722","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6600000262260437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320994","display_name":"Canada Research Chairs","ror":"https://ror.org/0517h6h17"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1968956770","https://openalex.org/W2002052017","https://openalex.org/W2090396746","https://openalex.org/W2111772099","https://openalex.org/W2114634479","https://openalex.org/W2126759918","https://openalex.org/W2131488240","https://openalex.org/W2152376358","https://openalex.org/W2157609369"],"related_works":["https://openalex.org/W1548647706","https://openalex.org/W2501692008","https://openalex.org/W4386224683","https://openalex.org/W4214500667","https://openalex.org/W4360974335","https://openalex.org/W3120791867","https://openalex.org/W1847525600","https://openalex.org/W4385546015","https://openalex.org/W2378756474","https://openalex.org/W2962747114"],"abstract_inverted_index":{"Heart":[0],"Rate":[1],"variability":[2,7],"(HRV)":[3],"is":[4,12,62],"the":[5,15,23,76,92,117,173,205],"inter-beat":[6],"in":[8,55,172,185],"heart":[9],"rate":[10],"and":[11,19,49,95,108,135,140],"moderated":[13],"by":[14],"balance":[16],"of":[17,22,78,146,207],"sympathetic":[18,44],"parasympathetic":[20,46],"divisions":[21],"autonomic":[24,192],"nervous":[25,193],"system.":[26],"Electrocardiography":[27],"(ECG)":[28],"can":[29],"be":[30,53],"utilized":[31,132],"to":[32,37,45,65,133,200,203],"obtain":[33],"Low":[34],"frequency":[35,39],"(LF)":[36],"high":[38],"(HF)":[40],"ratios":[41,51],"that":[42,181],"represent":[43],"response,":[47],"respectively":[48],"these":[50],"may":[52,198],"increased":[54],"people":[56],"with":[57,112],"chronic":[58],"pain.":[59,72],"Spinal":[60],"manipulation":[61,80,163,176],"often":[63],"used":[64],"manage":[66],"musculoskeletal":[67],"disorders":[68],"such":[69],"as":[70],"neck":[71,89,114],"This":[73,196],"study":[74,197],"assesses":[75],"influence":[77],"cervical":[79],"on":[81,152],"HRV":[82,153],"using":[83],"LF/HF":[84],"ratio.":[85],"Ten":[86,110],"subjects":[87,111],"without":[88],"pain":[90,115],"formed":[91],"control":[93],"condition":[94,100,177],"passive":[96],"head":[97,104],"movement":[98],"(PHM)":[99],"during":[101,175],"which":[102],"their":[103],"was":[105,123,131,182],"flexed,":[106],"extended":[107],"rotated.":[109],"subclinical":[113],"underwent":[116],"same":[118],"conditions.":[119],"A":[120],"separate":[121],"session":[122],"performed":[124],"for":[125],"an":[126],"actual":[127],"manipulation.":[128],"LabChart\u2122":[129],"software":[130],"collect":[134],"analyze":[136],"five":[137],"minute":[138],"pre":[139],"post":[141],"R-R":[142],"intervals.":[143],"Repeated":[144],"measures":[145],"ANOVA":[147],"demonstrated":[148],"significant":[149,170,191],"interaction":[150],"effect":[151],"(F":[154],"(1,":[155],"18)":[156],"=":[157,160,179],"6.841,":[158],"p":[159],"0.018)":[161],"following":[162],"vs.":[164],"PHM.":[165],"Subsequent":[166],"analysis":[167],"showed":[168],"a":[169,190],"decrease":[171],"ratio":[174],"(p":[178],"0.0316),":[180],"not":[183],"seen":[184],"any":[186],"other":[187],"conditions,":[188],"suggesting":[189],"system":[194],"alteration.":[195],"lead":[199],"new":[201],"techniques":[202],"assess":[204],"effectiveness":[206],"various":[208],"treatment":[209],"interventions.":[210]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}