{"id":"https://openalex.org/W2317132109","doi":"https://doi.org/10.1109/embc.2014.6944101","title":"Computer-aided detection of brain metastases using a three-dimensional template-based matching algorithm","display_name":"Computer-aided detection of brain metastases using a three-dimensional template-based matching algorithm","publication_year":2014,"publication_date":"2014-08-01","ids":{"openalex":"https://openalex.org/W2317132109","doi":"https://doi.org/10.1109/embc.2014.6944101","mag":"2317132109","pmid":"https://pubmed.ncbi.nlm.nih.gov/25570469"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2014.6944101","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6944101","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10251/84912","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086848200","display_name":"\u00darsula P\u00e9rez\u2010Ram\u00edrez","orcid":"https://orcid.org/0000-0002-0056-563X"},"institutions":[{"id":"https://openalex.org/I60053951","display_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","ror":"https://ror.org/01460j859","country_code":"ES","type":"education","lineage":["https://openalex.org/I60053951"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Ursula Perez-Ramirez","raw_affiliation_strings":["Center for Biomaterials and Tissue Engineering, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain"],"affiliations":[{"raw_affiliation_string":"Center for Biomaterials and Tissue Engineering, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain","institution_ids":["https://openalex.org/I60053951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049739186","display_name":"Estanislao Arana","orcid":"https://orcid.org/0000-0002-1884-7854"},"institutions":[{"id":"https://openalex.org/I4210103093","display_name":"Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda","ror":"https://ror.org/01fh9k283","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210103093"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Estanislao Arana","raw_affiliation_strings":["Radiology Department, Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda, Valencia, Spain"],"affiliations":[{"raw_affiliation_string":"Radiology Department, Fundaci\u00f3n Instituto Valenciano de Oncolog\u00eda, Valencia, Spain","institution_ids":["https://openalex.org/I4210103093"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039695934","display_name":"David Moratal","orcid":"https://orcid.org/0000-0002-2825-3646"},"institutions":[{"id":"https://openalex.org/I60053951","display_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","ror":"https://ror.org/01460j859","country_code":"ES","type":"education","lineage":["https://openalex.org/I60053951"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"David Moratal","raw_affiliation_strings":["Center for Biomaterials and Tissue Engineering, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain"],"affiliations":[{"raw_affiliation_string":"Center for Biomaterials and Tissue Engineering, Universitat Polit\u00e8cnica de Val\u00e8ncia, Valencia, Spain","institution_ids":["https://openalex.org/I60053951"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5086848200"],"corresponding_institution_ids":["https://openalex.org/I60053951"],"apc_list":null,"apc_paid":null,"fwci":0.7673,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.75992727,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"29","issue":null,"first_page":"2384","last_page":"2387"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/false-positive-paradox","display_name":"False positive paradox","score":0.8122258186340332},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.5873813033103943},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.5571159720420837},{"id":"https://openalex.org/keywords/reduction","display_name":"Reduction (mathematics)","score":0.5067899823188782},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4910147190093994},{"id":"https://openalex.org/keywords/true-positive-rate","display_name":"True positive rate","score":0.4828775227069855},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.46953001618385315},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4686509966850281},{"id":"https://openalex.org/keywords/false-positive-rate","display_name":"False positive rate","score":0.45598912239074707},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.44647490978240967},{"id":"https://openalex.org/keywords/matching","display_name":"Matching (statistics)","score":0.4411980211734772},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3017527461051941},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2569316029548645},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.19618085026741028},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.16650989651679993}],"concepts":[{"id":"https://openalex.org/C64869954","wikidata":"https://www.wikidata.org/wiki/Q1859747","display_name":"False positive paradox","level":2,"score":0.8122258186340332},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.5873813033103943},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5571159720420837},{"id":"https://openalex.org/C111335779","wikidata":"https://www.wikidata.org/wiki/Q3454686","display_name":"Reduction (mathematics)","level":2,"score":0.5067899823188782},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4910147190093994},{"id":"https://openalex.org/C2989486834","wikidata":"https://www.wikidata.org/wiki/Q3808900","display_name":"True positive rate","level":2,"score":0.4828775227069855},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46953001618385315},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4686509966850281},{"id":"https://openalex.org/C95922358","wikidata":"https://www.wikidata.org/wiki/Q5432725","display_name":"False positive rate","level":2,"score":0.45598912239074707},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.44647490978240967},{"id":"https://openalex.org/C165064840","wikidata":"https://www.wikidata.org/wiki/Q1321061","display_name":"Matching (statistics)","level":2,"score":0.4411980211734772},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3017527461051941},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2569316029548645},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19618085026741028},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.16650989651679993},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000556","qualifier_name":"secondary","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003936","descriptor_name":"Diagnosis, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2014.6944101","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6944101","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:25570469","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25570469","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:riunet.upv.es:10251/84912","is_oa":true,"landing_page_url":"http://hdl.handle.net/10251/84912","pdf_url":null,"source":{"id":"https://openalex.org/S4306401500","display_name":"RiuNet (Politechnical University of Valencia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I60053951","host_organization_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","host_organization_lineage":["https://openalex.org/I60053951"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:riunet.upv.es:10251/84912","is_oa":true,"landing_page_url":"http://hdl.handle.net/10251/84912","pdf_url":null,"source":{"id":"https://openalex.org/S4306401500","display_name":"RiuNet (Politechnical University of Valencia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I60053951","host_organization_name":"Universitat Polit\u00e8cnica de Val\u00e8ncia","host_organization_lineage":["https://openalex.org/I60053951"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.6800000071525574,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W216012752","https://openalex.org/W1512548042","https://openalex.org/W1551042121","https://openalex.org/W1974473991","https://openalex.org/W1979835502","https://openalex.org/W1981153563","https://openalex.org/W2041812800","https://openalex.org/W2071881327","https://openalex.org/W2081322940","https://openalex.org/W2116040950","https://openalex.org/W2116654471","https://openalex.org/W2118979849","https://openalex.org/W2153826401","https://openalex.org/W2382084373","https://openalex.org/W3211330693","https://openalex.org/W6608647691"],"related_works":["https://openalex.org/W2027184711","https://openalex.org/W3119537175","https://openalex.org/W101962219","https://openalex.org/W2951146195","https://openalex.org/W4292605373","https://openalex.org/W2735767444","https://openalex.org/W3123215897","https://openalex.org/W2810356275","https://openalex.org/W2208028087","https://openalex.org/W3164550676"],"abstract_inverted_index":{"The":[0],"purpose":[1],"of":[2,22,72,106],"this":[3],"work":[4],"was":[5,38,100],"to":[6,49,94,103],"develop":[7],"an":[8],"algorithm":[9,68],"for":[10,78],"detecting":[11],"brain":[12,32,65],"metastases":[13],"in":[14,40],"magnetic":[15],"resonance":[16],"imaging":[17],"(MRI),":[18],"emphasizing":[19],"the":[20,31,41,76],"reduction":[21],"false":[23,79,86],"positives.":[24],"Firstly,":[25],"three-dimensional":[26],"templates":[27],"were":[28,84],"cross-correlated":[29],"with":[30],"volume.":[33],"Afterwards,":[34],"each":[35],"lesion":[36],"candidate":[37],"segmented":[39],"three":[42],"orthogonal":[43],"views":[44],"as":[45,54],"a":[46,58,70,104],"previous":[47],"step":[48],"remove":[50],"elongated":[51],"structures":[52],"such":[53],"blood":[55],"vessels.":[56],"In":[57],"database":[59],"containing":[60],"19":[61],"patients":[62],"and":[63,96],"62":[64],"metastases,":[66],"detection":[67],"showed":[69],"sensitivity":[71,105],"93.55%.":[73],"After":[74],"applying":[75],"method":[77],"positive":[80,87],"reduction,":[81],"encouraging":[82],"results":[83],"obtained:":[85],"rate":[88],"per":[89],"slice":[90],"decreased":[91],"from":[92],"0.64":[93],"0.15":[95],"only":[97],"one":[98],"metastasis":[99],"removed,":[101],"leading":[102],"91.94%.":[107]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}