{"id":"https://openalex.org/W2334849602","doi":"https://doi.org/10.1109/embc.2014.6943694","title":"Using functional MRI alone for localization in focal epilepsy","display_name":"Using functional MRI alone for localization in focal epilepsy","publication_year":2014,"publication_date":"2014-08-01","ids":{"openalex":"https://openalex.org/W2334849602","doi":"https://doi.org/10.1109/embc.2014.6943694","mag":"2334849602","pmid":"https://pubmed.ncbi.nlm.nih.gov/25570062"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2014.6943694","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6943694","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027192401","display_name":"Clara H. Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clara H. Zhang","raw_affiliation_strings":["Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028178400","display_name":"Yunfeng Lu","orcid":"https://orcid.org/0000-0002-4869-9303"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yunfeng Lu","raw_affiliation_strings":["Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068014315","display_name":"Benjamin H. Brinkmann","orcid":"https://orcid.org/0000-0002-2392-8608"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Brinkmann","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008875929","display_name":"Kirk M. Welker","orcid":"https://orcid.org/0000-0003-1293-2887"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kirk Welker","raw_affiliation_strings":["Department of Radiology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070511138","display_name":"Gregory A. Worrell","orcid":"https://orcid.org/0000-0003-2916-0553"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory Worrell","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100671882","display_name":"Bin He","orcid":"https://orcid.org/0000-0003-2944-8602"},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bin He","raw_affiliation_strings":["Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.425,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.59911277,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"22","issue":null,"first_page":"730","last_page":"733"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11447","display_name":"Blind Source Separation Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1711","display_name":"Signal Processing"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.8285977840423584},{"id":"https://openalex.org/keywords/epilepsy-surgery","display_name":"Epilepsy surgery","score":0.6403268575668335},{"id":"https://openalex.org/keywords/intractable-epilepsy","display_name":"Intractable epilepsy","score":0.5018250942230225},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.48091623187065125},{"id":"https://openalex.org/keywords/lateralization-of-brain-function","display_name":"Lateralization of brain function","score":0.43598172068595886},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.4256502389907837},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.42262566089630127},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.4206625819206238},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3407728672027588},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3402807116508484}],"concepts":[{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.8285977840423584},{"id":"https://openalex.org/C2780803581","wikidata":"https://www.wikidata.org/wiki/Q1347108","display_name":"Epilepsy surgery","level":3,"score":0.6403268575668335},{"id":"https://openalex.org/C3017633486","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Intractable epilepsy","level":3,"score":0.5018250942230225},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48091623187065125},{"id":"https://openalex.org/C79840881","wikidata":"https://www.wikidata.org/wiki/Q1080497","display_name":"Lateralization of brain function","level":2,"score":0.43598172068595886},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4256502389907837},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.42262566089630127},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4206625819206238},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3407728672027588},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3402807116508484}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004828","descriptor_name":"Epilepsies, Partial","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004828","descriptor_name":"Epilepsies, Partial","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D004828","descriptor_name":"Epilepsies, Partial","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013647","descriptor_name":"Task Performance and Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013647","descriptor_name":"Task Performance and Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013647","descriptor_name":"Task Performance and Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2014.6943694","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2014.6943694","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:25570062","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25570062","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6800000071525574,"id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G2014274978","display_name":null,"funder_award_id":"NS076408","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G7655635647","display_name":null,"funder_award_id":"EB007920","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G8353256489","display_name":null,"funder_award_id":"EY023101","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G8510125652","display_name":null,"funder_award_id":"EB006433","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G976423270","display_name":null,"funder_award_id":"HL117664","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1760829075","https://openalex.org/W1886029756","https://openalex.org/W1933144700","https://openalex.org/W1997260622","https://openalex.org/W2003637528","https://openalex.org/W2020001168","https://openalex.org/W2043298666","https://openalex.org/W2070348480","https://openalex.org/W2106396500","https://openalex.org/W2115000201","https://openalex.org/W2128390591","https://openalex.org/W2160450584","https://openalex.org/W2161319723","https://openalex.org/W2162010696","https://openalex.org/W2336956813","https://openalex.org/W3095130350"],"related_works":["https://openalex.org/W1991680404","https://openalex.org/W4324330064","https://openalex.org/W4361226145","https://openalex.org/W2105669039","https://openalex.org/W3034559903","https://openalex.org/W2040524797","https://openalex.org/W2171270716","https://openalex.org/W2047552691","https://openalex.org/W2300658761","https://openalex.org/W2621068020"],"abstract_inverted_index":{"In":[0,87,103],"the":[1,9,55,81,104,124,131,162,172],"present":[2],"study,":[3],"we":[4],"developed":[5,69],"a":[6,60],"method":[7,76,112,151],"for":[8,17,142,171],"purpose":[10],"of":[11,32,62,108,136,174],"localizing":[12],"epilepsy":[13,22,72,177],"related":[14,73],"hemodynamic":[15],"foci":[16],"patients":[18,35,143],"suffering":[19],"intractable":[20,37,145,175],"focal":[21,38,147,176],"using":[23],"resting":[24],"state":[25],"fMRI":[26,56,137],"alone.":[27],"We":[28],"studied":[29],"two":[30],"groups":[31],"subjects:":[33],"five":[34,89],"with":[36,84,100,115,144],"epilepsy,":[39],"and":[40,59,118,133,156],"ten":[41],"healthy":[42,82,109],"volunteers":[43],"performing":[44],"motor":[45,85,105,126],"tasks.":[46,86,127],"Spatial":[47],"independent":[48,63],"component":[49,64],"analysis":[50],"(ICA)":[51],"was":[52,68,77,93],"performed":[53],"on":[54],"alone":[57,138],"data":[58],"set":[61],"(IC)":[65],"selection":[66],"criteria":[67],"to":[70,158,164],"identify":[71],"ICs.":[74],"The":[75,149],"then":[78],"evaluated":[79],"in":[80,139,154,167],"group":[83],"all":[88],"surgery":[90],"patients,":[91],"there":[92],"at":[94],"least":[95],"one":[96],"identified":[97],"IC":[98],"concordant":[99,116],"surgical":[101],"resection.":[102],"task":[106],"study":[107],"subjects,":[110],"our":[111],"revealed":[113],"components":[114],"spatial":[117],"temporal":[119],"features":[120],"as":[121],"expected":[122],"from":[123],"unilateral":[125,146],"These":[128],"results":[129],"suggest":[130],"lateralization":[132],"localization":[134],"value":[135],"presurgical":[140,169],"evaluation":[141],"epilepsy.":[148],"proposed":[150],"is":[152],"noninvasive":[153],"nature":[155],"easy":[157],"implement.":[159],"It":[160],"has":[161],"potential":[163],"be":[165],"incorporated":[166],"current":[168],"workup":[170],"diagnosis":[173],"patients.":[178]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}