{"id":"https://openalex.org/W2129446002","doi":"https://doi.org/10.1109/embc.2013.6611053","title":"Cell-specific modeling of retinal ganglion cell electrical activity","display_name":"Cell-specific modeling of retinal ganglion cell electrical activity","publication_year":2013,"publication_date":"2013-07-01","ids":{"openalex":"https://openalex.org/W2129446002","doi":"https://doi.org/10.1109/embc.2013.6611053","mag":"2129446002"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2013.6611053","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2013.6611053","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088113248","display_name":"Tianruo Guo","orcid":"https://orcid.org/0000-0001-6348-6771"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Tianruo Guo","raw_affiliation_strings":["Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065277088","display_name":"David Tsai","orcid":"https://orcid.org/0000-0002-5931-1861"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David Tsai","raw_affiliation_strings":["University of New South Wales, Sydney, NSW, AU","Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"University of New South Wales, Sydney, NSW, AU","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027549089","display_name":"John W. Morley","orcid":"https://orcid.org/0000-0001-9246-853X"},"institutions":[{"id":"https://openalex.org/I63525965","display_name":"Western Sydney University","ror":"https://ror.org/03t52dk35","country_code":"AU","type":"education","lineage":["https://openalex.org/I63525965"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"John W. Morley","raw_affiliation_strings":["School of Medicine, University of Western Sydney, Australia","School of Medicine, University of Western Sydney Sydney, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Medicine, University of Western Sydney, Australia","institution_ids":["https://openalex.org/I63525965"]},{"raw_affiliation_string":"School of Medicine, University of Western Sydney Sydney, NSW, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027574689","display_name":"Gregg J. Suaning","orcid":"https://orcid.org/0000-0003-1918-3313"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Gregg J. Suaning","raw_affiliation_strings":["Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060602596","display_name":"Nigel H. Lovell","orcid":"https://orcid.org/0000-0003-1637-1079"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Nigel H. Lovell","raw_affiliation_strings":["Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049381733","display_name":"Socrates Dokos","orcid":"https://orcid.org/0000-0002-7399-2712"},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Socrates Dokos","raw_affiliation_strings":["Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"Grad. Sch. of Biomed. Eng., Univ. of New South Wales, Sydney, NSW, Australia","institution_ids":["https://openalex.org/I31746571"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5088113248"],"corresponding_institution_ids":["https://openalex.org/I31746571"],"apc_list":null,"apc_paid":null,"fwci":1.2394,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.76373447,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"140","issue":null,"first_page":"6539","last_page":"6542"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-ganglion-cell","display_name":"Retinal ganglion cell","score":0.6446590423583984},{"id":"https://openalex.org/keywords/retina","display_name":"Retina","score":0.5689781308174133},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.5083386301994324},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4882490932941437},{"id":"https://openalex.org/keywords/ganglion","display_name":"Ganglion","score":0.4732801616191864},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.47063279151916504},{"id":"https://openalex.org/keywords/ion-channel","display_name":"Ion channel","score":0.4616708755493164},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.4307262599468231},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3297352194786072},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.23172220587730408}],"concepts":[{"id":"https://openalex.org/C2777624874","wikidata":"https://www.wikidata.org/wiki/Q927337","display_name":"Retinal ganglion cell","level":3,"score":0.6446590423583984},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.5689781308174133},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.5083386301994324},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4882490932941437},{"id":"https://openalex.org/C2781334511","wikidata":"https://www.wikidata.org/wiki/Q108158","display_name":"Ganglion","level":2,"score":0.4732801616191864},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.47063279151916504},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.4616708755493164},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4307262599468231},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3297352194786072},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23172220587730408},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/embc.2013.6611053","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2013.6611053","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320965","display_name":"University of New South Wales","ror":"https://ror.org/03r8z3t63"},{"id":"https://openalex.org/F4320334704","display_name":"Australian Research Council","ror":"https://ror.org/05mmh0f86"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1585043634","https://openalex.org/W1975579625","https://openalex.org/W1985940938","https://openalex.org/W1998002610","https://openalex.org/W2006352578","https://openalex.org/W2018848816","https://openalex.org/W2027492218","https://openalex.org/W2047141148","https://openalex.org/W2065711691","https://openalex.org/W2080100407","https://openalex.org/W2090932282","https://openalex.org/W2117120818","https://openalex.org/W2137336332","https://openalex.org/W2137973339","https://openalex.org/W2156639802","https://openalex.org/W2164066151","https://openalex.org/W6635257888"],"related_works":["https://openalex.org/W2018007208","https://openalex.org/W2062427031","https://openalex.org/W2031850466","https://openalex.org/W2029897755","https://openalex.org/W2101178803","https://openalex.org/W2050076300","https://openalex.org/W2051904086","https://openalex.org/W1989322055","https://openalex.org/W2055988555","https://openalex.org/W1966988327"],"abstract_inverted_index":{"Variations":[0],"in":[1,37,87],"ionic":[2,82,90],"channel":[3,68,83,91],"expression":[4],"and":[5,30,33,65,93],"anatomical":[6],"properties":[7,32,69],"can":[8],"influence":[9],"how":[10],"different":[11],"retinal":[12],"ganglion":[13],"cell":[14,94],"(RGC)":[15],"types":[16],"process":[17],"synaptic":[18],"information.":[19],"Computational":[20],"modeling":[21],"approaches":[22],"allow":[23],"us":[24],"to":[25,56,70],"precisely":[26],"control":[27],"these":[28],"biophysical":[29],"physical":[31],"isolate":[34],"their":[35,88],"effects":[36],"shaping":[38],"RGC":[39,52,71,78],"firing":[40],"patterns.":[41],"In":[42,74],"this":[43],"study,":[44],"three":[45],"models":[46,79],"based":[47],"on":[48],"realistic":[49],"representations":[50],"of":[51,60,63],"morphologies":[53],"were":[54],"used":[55],"simulate":[57],"the":[58,77],"contribution":[59],"spatial":[61],"structure":[62],"neurons":[64],"membrane":[66],"ion":[67],"electrical":[72],"activity.":[73],"all":[75],"simulations,":[76],"shared":[80],"common":[81],"kinetics,":[84],"differing":[85],"only":[86],"regional":[89],"distributions":[92],"morphology.":[95]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2016-06-24T00:00:00"}
