{"id":"https://openalex.org/W2046618632","doi":"https://doi.org/10.1109/embc.2013.6609872","title":"Dynamics of hemoglobin states in the sensorimotor cortex during motor tasks: A functional near infrared spectroscopy study","display_name":"Dynamics of hemoglobin states in the sensorimotor cortex during motor tasks: A functional near infrared spectroscopy study","publication_year":2013,"publication_date":"2013-07-01","ids":{"openalex":"https://openalex.org/W2046618632","doi":"https://doi.org/10.1109/embc.2013.6609872","mag":"2046618632","pmid":"https://pubmed.ncbi.nlm.nih.gov/24110059"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2013.6609872","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2013.6609872","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067486095","display_name":"Chia\u2010Feng Lu","orcid":"https://orcid.org/0000-0003-1344-9950"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I4210087697","display_name":"National Yang Ming University Hospital","ror":"https://ror.org/003xdw211","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210087697"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chia-Feng Lu","raw_affiliation_strings":["Dept. of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","Dept. of Biomed. Imaging & Radiol. Sci., Nat. Yang Ming Univ., Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I4210087697"]},{"raw_affiliation_string":"Dept. of Biomed. Imaging & Radiol. Sci., Nat. Yang Ming Univ., Taipei, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111731382","display_name":"Shin Teng","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I4210087697","display_name":"National Yang Ming University Hospital","ror":"https://ror.org/003xdw211","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210087697"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Shin Teng","raw_affiliation_strings":["Dept. of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","Dept. of Biomed. Imaging & Radiol. Sci., Nat. Yang Ming Univ., Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I4210087697"]},{"raw_affiliation_string":"Dept. of Biomed. Imaging & Radiol. Sci., Nat. Yang Ming Univ., Taipei, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080942813","display_name":"Yu\u2010Te Wu","orcid":"https://orcid.org/0000-0002-6942-0340"},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]},{"id":"https://openalex.org/I4210087697","display_name":"National Yang Ming University Hospital","ror":"https://ror.org/003xdw211","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210087697"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yu-Te Wu","raw_affiliation_strings":["Dept. of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","Dept. of Biomed. Imaging & Radiol. Sci., Nat. Yang Ming Univ., Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, ROC","institution_ids":["https://openalex.org/I148366613","https://openalex.org/I4210087697"]},{"raw_affiliation_string":"Dept. of Biomed. Imaging & Radiol. Sci., Nat. Yang Ming Univ., Taipei, Taiwan","institution_ids":["https://openalex.org/I148366613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9845,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.84099137,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"2013","issue":null,"first_page":"1803","last_page":"1806"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/functional-near-infrared-spectroscopy","display_name":"Functional near-infrared spectroscopy","score":0.7858269810676575},{"id":"https://openalex.org/keywords/motor-cortex","display_name":"Motor cortex","score":0.49502819776535034},{"id":"https://openalex.org/keywords/spectroscopy","display_name":"Spectroscopy","score":0.47959959506988525},{"id":"https://openalex.org/keywords/infrared-spectroscopy","display_name":"Infrared spectroscopy","score":0.47705093026161194},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.4306558668613434},{"id":"https://openalex.org/keywords/infrared","display_name":"Infrared","score":0.4259127676486969},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"Neurophysiology","score":0.4134061634540558},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3888917863368988},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.32434678077697754},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.30996859073638916},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.2605505585670471},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.16708576679229736},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"Prefrontal cortex","score":0.16300389170646667},{"id":"https://openalex.org/keywords/quantum-mechanics","display_name":"Quantum mechanics","score":0.0737709105014801}],"concepts":[{"id":"https://openalex.org/C130796691","wikidata":"https://www.wikidata.org/wiki/Q750537","display_name":"Functional near-infrared spectroscopy","level":4,"score":0.7858269810676575},{"id":"https://openalex.org/C2778373776","wikidata":"https://www.wikidata.org/wiki/Q18696","display_name":"Motor cortex","level":3,"score":0.49502819776535034},{"id":"https://openalex.org/C32891209","wikidata":"https://www.wikidata.org/wiki/Q483666","display_name":"Spectroscopy","level":2,"score":0.47959959506988525},{"id":"https://openalex.org/C153642686","wikidata":"https://www.wikidata.org/wiki/Q70906","display_name":"Infrared spectroscopy","level":2,"score":0.47705093026161194},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4306558668613434},{"id":"https://openalex.org/C158355884","wikidata":"https://www.wikidata.org/wiki/Q11388","display_name":"Infrared","level":2,"score":0.4259127676486969},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.4134061634540558},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3888917863368988},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.32434678077697754},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.30996859073638916},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2605505585670471},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.16708576679229736},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.16300389170646667},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0737709105014801},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019265","descriptor_name":"Spectroscopy, Near-Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019265","descriptor_name":"Spectroscopy, Near-Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019265","descriptor_name":"Spectroscopy, Near-Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D066191","descriptor_name":"Sensorimotor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2013.6609872","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2013.6609872","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","raw_type":"proceedings-article"},{"id":"pmid:24110059","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24110059","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.46000000834465027,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1528119265","https://openalex.org/W2049169845","https://openalex.org/W2058875695","https://openalex.org/W2064979714","https://openalex.org/W2071714163","https://openalex.org/W2090793463","https://openalex.org/W2170876631","https://openalex.org/W2232055761"],"related_works":["https://openalex.org/W2135375667","https://openalex.org/W4323652357","https://openalex.org/W2023765240","https://openalex.org/W3015655413","https://openalex.org/W4236933654","https://openalex.org/W2008512696","https://openalex.org/W2916853706","https://openalex.org/W2490963019","https://openalex.org/W2018674345","https://openalex.org/W2469340274"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"we":[3],"used":[4],"functional":[5,176],"near":[6],"infrared":[7],"spectroscopy":[8],"(fNIRS)":[9],"imaging":[10],"to":[11,125,162],"investigate":[12],"the":[13,28,39,58,80,96,106,112,127,142,147,163,169],"independent":[14],"levels":[15],"of":[16,41,68,108,144,149,159,175],"oxygenated,":[17],"deoxygenated,":[18],"and":[19,24,50,71,85,110],"total":[20],"hemoglobin":[21],"(oxy-Hb,":[22],"deoxy-Hb,":[23],"total-Hb,":[25],"respectively)":[26],"at":[27,89,130],"sensorimotor":[29],"cortex":[30,45,62],"during":[31,151],"hand-grasping":[32],"motor":[33,44,152],"tasks.":[34],"Our":[35],"results":[36],"showed":[37],"that":[38,79,136],"activation":[40,143,165],"contralateral":[42,59,90,100],"primary":[43,60],"(M1)":[46],"exhibited":[47],"increased":[48],"oxy-Hb":[49,70],"reduced":[51],"dexoy-Hb":[52],"after":[53],"hand":[54,81],"grasping":[55,82],"began.":[56],"Meanwhile,":[57],"somatosensory":[61],"(S1)":[63],"was":[64,93],"deactivated":[65],"with":[66,122,168],"reductions":[67],"both":[69],"deoxy-Hb":[72],"concentration.":[73],"The":[74,99],"Hb":[75],"circulation":[76],"patterns":[77],"indicated":[78],"demanded":[83],"rapid":[84],"sufficient":[86],"O2":[87,123],"supply":[88],"M1,":[91],"which":[92,154],"achieved":[94],"by":[95],"local":[97,113],"vasodilation.":[98],"S1":[101,150],"presented":[102,135],"decreased":[103],"total-Hb":[104],"via":[105],"mechanism":[107],"vasoconstriction,":[109],"maintained":[111],"oxygenation":[114],"level":[115],"in":[116,166],"a":[117],"relatively":[118],"stable":[119],"state":[120],"(mostly":[121],"debt)":[124],"compensate":[126],"blood":[128],"demanding":[129],"nearby":[131],"M1.":[132],"This":[133],"study":[134],"fNIRS":[137],"data":[138],"can":[139,155],"efficiently":[140],"differentiate":[141],"M1":[145],"from":[146],"deactivation":[148],"tasks,":[153],"provide":[156],"full":[157],"interpretations":[158],"hemodynamic":[160],"response":[161],"neuronal":[164],"comparison":[167],"Blood":[170],"Oxygenation":[171],"Level":[172],"Dependent":[173],"signal":[174],"magnetic":[177],"resonance":[178],"imaging.":[179]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}