{"id":"https://openalex.org/W2024597619","doi":"https://doi.org/10.1109/embc.2012.6346752","title":"Estimation of excitatory drive from sparse motoneuron sampling","display_name":"Estimation of excitatory drive from sparse motoneuron sampling","publication_year":2012,"publication_date":"2012-08-01","ids":{"openalex":"https://openalex.org/W2024597619","doi":"https://doi.org/10.1109/embc.2012.6346752","mag":"2024597619","pmid":"https://pubmed.ncbi.nlm.nih.gov/23366713"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2012.6346752","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346752","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100411272","display_name":"Yao Li","orcid":"https://orcid.org/0000-0003-3656-5858"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yao Li","raw_affiliation_strings":["Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA. Yao.Li.1@usc.edu","Department of Biomedical Engineering, University of Southern California, Los Angeles, USA, 90089"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA. Yao.Li.1@usc.edu","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Southern California, Los Angeles, USA, 90089","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110102398","display_name":"Lauren H. Smith","orcid":null},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I1324242722","display_name":"Shirley Ryan AbilityLab","ror":"https://ror.org/02ja0m249","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1324242722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. H. Smith","raw_affiliation_strings":["Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA","Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, IL, USA, 60611"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I1324242722"]},{"raw_affiliation_string":"Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, IL, USA, 60611","institution_ids":["https://openalex.org/I1324242722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018478365","display_name":"Levi J. Hargrove","orcid":"https://orcid.org/0000-0002-1705-0050"},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I1324242722","display_name":"Shirley Ryan AbilityLab","ror":"https://ror.org/02ja0m249","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1324242722"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. J. Hargrove","raw_affiliation_strings":["Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA","Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, IL, USA, 60611"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, IL, USA","institution_ids":["https://openalex.org/I111979921","https://openalex.org/I1324242722"]},{"raw_affiliation_string":"Center for Bionic Medicine at the Rehabilitation Institute of Chicago and the Department of Physical Medicine and Rehabilitation, Northwestern University, IL, USA, 60611","institution_ids":["https://openalex.org/I1324242722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024911410","display_name":"Douglas J. Weber","orcid":"https://orcid.org/0000-0002-9782-3497"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. J. Weber","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA","Department of Physical Medicine and Rehabilitation, University of Pittsburgh, PA USA 15260"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, University of Pittsburgh, PA USA 15260","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075298131","display_name":"Gerald E. Loeb","orcid":"https://orcid.org/0000-0002-6753-634X"},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. E. Loeb","raw_affiliation_strings":["Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA","Department of Biomedical Engineering, University of Southern California, Los Angeles, USA, 90089"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Southern California, Los Angeles, USA, 90089","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.14790168,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"40","issue":null,"first_page":"3628","last_page":"3631"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10784","display_name":"Muscle activation and electromyography studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10784","display_name":"Muscle activation and electromyography studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6692157983779907},{"id":"https://openalex.org/keywords/reinnervation","display_name":"Reinnervation","score":0.5467360019683838},{"id":"https://openalex.org/keywords/mechatronics","display_name":"Mechatronics","score":0.4595105051994324},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potential","display_name":"Excitatory postsynaptic potential","score":0.4455036222934723},{"id":"https://openalex.org/keywords/induction-motor","display_name":"Induction motor","score":0.44446444511413574},{"id":"https://openalex.org/keywords/sampling","display_name":"Sampling (signal processing)","score":0.4425981640815735},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3463577628135681},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.25464922189712524},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.23354244232177734},{"id":"https://openalex.org/keywords/voltage","display_name":"Voltage","score":0.2216593623161316},{"id":"https://openalex.org/keywords/detector","display_name":"Detector","score":0.21684151887893677},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.10082796216011047},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09035944938659668}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6692157983779907},{"id":"https://openalex.org/C2779649809","wikidata":"https://www.wikidata.org/wiki/Q7310406","display_name":"Reinnervation","level":2,"score":0.5467360019683838},{"id":"https://openalex.org/C28704281","wikidata":"https://www.wikidata.org/wiki/Q180165","display_name":"Mechatronics","level":2,"score":0.4595105051994324},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.4455036222934723},{"id":"https://openalex.org/C80962145","wikidata":"https://www.wikidata.org/wiki/Q207450","display_name":"Induction motor","level":3,"score":0.44446444511413574},{"id":"https://openalex.org/C140779682","wikidata":"https://www.wikidata.org/wiki/Q210868","display_name":"Sampling (signal processing)","level":3,"score":0.4425981640815735},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3463577628135681},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.25464922189712524},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.23354244232177734},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.2216593623161316},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.21684151887893677},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.10082796216011047},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09035944938659668},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2012.6346752","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346752","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:23366713","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23366713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.6600000262260437}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1907543087","https://openalex.org/W1964919144","https://openalex.org/W1987654118","https://openalex.org/W1996486908","https://openalex.org/W2010714646","https://openalex.org/W2035129249","https://openalex.org/W2095666645","https://openalex.org/W2113679924","https://openalex.org/W2125030820","https://openalex.org/W2135648815","https://openalex.org/W2166435243","https://openalex.org/W2167790067","https://openalex.org/W2168859550","https://openalex.org/W2181970214","https://openalex.org/W2323720232"],"related_works":["https://openalex.org/W2286739631","https://openalex.org/W2101562224","https://openalex.org/W2034799318","https://openalex.org/W2077564746","https://openalex.org/W1533035405","https://openalex.org/W2021237660","https://openalex.org/W1983337516","https://openalex.org/W21229474","https://openalex.org/W2042997292","https://openalex.org/W1964031293"],"abstract_inverted_index":{"It":[0],"is":[1,90],"possible":[2],"to":[3,17,26,51,92,177],"replace":[4],"amputated":[5,36],"limbs":[6],"with":[7],"mechatronic":[8],"prostheses,":[9],"but":[10,46],"their":[11],"operation":[12],"requires":[13],"the":[14,27,30,35,54,70,77,99,103,120,137],"user's":[15],"intentions":[16,101],"be":[18],"detected":[19],"and":[20,40,59,85,95,122,158],"converted":[21],"into":[22],"control":[23],"signals":[24,48],"sent":[25],"actuators.":[28],"Fortunately,":[29],"motoneurons":[31],"(MNs)":[32],"that":[33,75],"controlled":[34],"muscles":[37],"remain":[38],"intact":[39],"capable":[41],"of":[42,69,72,87,98,102,114,125,130,144,154],"generating":[43],"electrical":[44],"signals,":[45],"these":[47],"are":[49],"difficult":[50],"record.":[52],"Even":[53],"latest":[55],"microelectrode":[56],"array":[57],"technologies":[58],"targeted":[60],"motor":[61,73,78,115,132,138,170,180],"reinnervation":[62,171],"(TMR)":[63],"can":[64],"provide":[65],"only":[66],"sparse":[67],"sampling":[68],"hundreds":[71],"units":[74],"comprise":[76],"pool":[79,116],"for":[80,111],"each":[81],"muscle.":[82],"Simple":[83],"rectification":[84],"integration":[86],"such":[88],"records":[89],"likely":[91],"produce":[93],"noisy":[94],"delayed":[96],"estimates":[97],"actual":[100],"user.":[104],"We":[105,134],"have":[106],"developed":[107],"a":[108,126,150,168],"novel":[109],"algorithm":[110,140,163],"optimal":[112],"estimation":[113,139],"excitation":[117],"based":[118,148],"on":[119,149,167],"recruitment":[121,157],"firing":[123],"rates":[124],"small":[127],"number":[128],"(2-10)":[129],"discriminated":[131],"units.":[133,181],"first":[135],"derived":[136],"from":[141],"normal":[142],"patterns":[143],"modulated":[145],"MN":[146,156],"activity":[147],"previously":[151],"published":[152],"model":[153],"individual":[155],"asynchronous":[159],"frequency":[160],"modulation.":[161],"The":[162],"was":[164],"then":[165],"validated":[166],"target":[169],"subject":[172],"using":[173],"intramuscular":[174],"fine-wire":[175],"recordings":[176],"obtain":[178],"single":[179]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}
