{"id":"https://openalex.org/W1979475811","doi":"https://doi.org/10.1109/embc.2012.6346713","title":"Simultaneously extracted transient and steady-state evoked responses during general anesthesia: Variability of different rates","display_name":"Simultaneously extracted transient and steady-state evoked responses during general anesthesia: Variability of different rates","publication_year":2012,"publication_date":"2012-08-01","ids":{"openalex":"https://openalex.org/W1979475811","doi":"https://doi.org/10.1109/embc.2012.6346713","mag":"1979475811","pmid":"https://pubmed.ncbi.nlm.nih.gov/23366674"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2012.6346713","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346713","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027399931","display_name":"A. Castro-Llanos","orcid":null},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"A. Castro-Llanos","raw_affiliation_strings":["Department of Biomedical Engineering at the University of Miami, Florida, USA. a.castro10@umiami.edu","Department of Biomedical Engineering at the University of Miami, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering at the University of Miami, Florida, USA. a.castro10@umiami.edu","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Biomedical Engineering at the University of Miami, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026599908","display_name":"Jorge Boh\u00f3rquez","orcid":"https://orcid.org/0000-0001-5062-5381"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Bohorquez","raw_affiliation_strings":["Department of Biomedical Engineering, University of Miami, USA","Department of Biomedical Engineering at the University of Miami, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Miami, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Biomedical Engineering at the University of Miami, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013593382","display_name":"Richard R. McNeer","orcid":null},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. R. McNeer","raw_affiliation_strings":["Department of Anesthesiology, Miller School of Medicine, Miami, FL, USA","Department of Anesthesiology, Miller School of Medicine, Miami FL USA"],"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Miller School of Medicine, Miami, FL, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Anesthesiology, Miller School of Medicine, Miami FL USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061132373","display_name":"\u00d6. \u00d6zdamar","orcid":"https://orcid.org/0000-0001-8020-0659"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"O. Ozdamar","raw_affiliation_strings":["Department of Biomedical Engineering, University of Miami, Coral Gables, FL, USA","Department of Biomedical Engineering at the University of Miami in Coral Gables FL. 33214. USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Miami, Coral Gables, FL, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Biomedical Engineering at the University of Miami in Coral Gables FL. 33214. USA","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5027399931"],"corresponding_institution_ids":["https://openalex.org/I145608581"],"apc_list":null,"apc_paid":null,"fwci":0.1395,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.47329392,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"71","issue":null,"first_page":"3472","last_page":"3475"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.9876999855041504,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9786999821662903,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intraoperative-awareness","display_name":"Intraoperative Awareness","score":0.7616006731987},{"id":"https://openalex.org/keywords/anesthesia","display_name":"Anesthesia","score":0.7323264479637146},{"id":"https://openalex.org/keywords/anesthetic","display_name":"Anesthetic","score":0.644371747970581},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4954432249069214},{"id":"https://openalex.org/keywords/transient","display_name":"Transient (computer programming)","score":0.46902361512184143},{"id":"https://openalex.org/keywords/deconvolution","display_name":"Deconvolution","score":0.4647841453552246},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.461132675409317},{"id":"https://openalex.org/keywords/steady-state","display_name":"Steady state (chemistry)","score":0.441913366317749},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.25589749217033386},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.1540081799030304},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.1389687955379486}],"concepts":[{"id":"https://openalex.org/C2910377794","wikidata":"https://www.wikidata.org/wiki/Q1671572","display_name":"Intraoperative Awareness","level":3,"score":0.7616006731987},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.7323264479637146},{"id":"https://openalex.org/C2778162923","wikidata":"https://www.wikidata.org/wiki/Q4990531","display_name":"Anesthetic","level":2,"score":0.644371747970581},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4954432249069214},{"id":"https://openalex.org/C2780799671","wikidata":"https://www.wikidata.org/wiki/Q17087362","display_name":"Transient (computer programming)","level":2,"score":0.46902361512184143},{"id":"https://openalex.org/C174576160","wikidata":"https://www.wikidata.org/wiki/Q1183700","display_name":"Deconvolution","level":2,"score":0.4647841453552246},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.461132675409317},{"id":"https://openalex.org/C8171440","wikidata":"https://www.wikidata.org/wiki/Q903414","display_name":"Steady state (chemistry)","level":2,"score":0.441913366317749},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.25589749217033386},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1540081799030304},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.1389687955379486},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000161","descriptor_name":"Acoustic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000161","descriptor_name":"Acoustic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000161","descriptor_name":"Acoustic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000768","descriptor_name":"Anesthesia, General","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000768","descriptor_name":"Anesthesia, General","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000768","descriptor_name":"Anesthesia, General","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001364","descriptor_name":"Awareness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001364","descriptor_name":"Awareness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001364","descriptor_name":"Awareness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005071","descriptor_name":"Evoked Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007432","descriptor_name":"Intraoperative Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007432","descriptor_name":"Intraoperative Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007432","descriptor_name":"Intraoperative Period","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2012.6346713","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346713","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:23366674","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23366674","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1979081752","https://openalex.org/W2003269031","https://openalex.org/W2017286875","https://openalex.org/W2030641211","https://openalex.org/W2043210702","https://openalex.org/W2072983807","https://openalex.org/W2112172160","https://openalex.org/W2146930155","https://openalex.org/W2151756560"],"related_works":["https://openalex.org/W2106512568","https://openalex.org/W2159465694","https://openalex.org/W2077550944","https://openalex.org/W2030822348","https://openalex.org/W1964722880","https://openalex.org/W2890578400","https://openalex.org/W2909452000","https://openalex.org/W2019257762","https://openalex.org/W2151497195","https://openalex.org/W2131798818"],"abstract_inverted_index":{"Unintended":[0],"intraoperative":[1,21,32],"awareness":[2,22,33],"occurs":[3],"in":[4,97,111,128,161,191],"one":[5,12],"to":[6,30,44,60,99,121,152,158],"two":[7],"individuals":[8],"out":[9],"of":[10,64,150,171,203],"every":[11],"thousand":[13],"treated":[14],"with":[15,84],"general":[16,115,144],"anesthesia.":[17,65],"Patients":[18],"that":[19,53,140,159],"experience":[20],"have":[23,51],"significant":[24],"post-operative":[25],"psychological":[26],"sequelae.":[27],"The":[28,137,188],"ability":[29],"detect":[31],"is":[34,194],"currently":[35],"suboptimal":[36],"because":[37],"the":[38,62,77,123,165,169,200],"mechanism":[39],"employed":[40,190],"by":[41],"anesthetic":[42],"drugs":[43],"impair":[45],"consciousness":[46],"remains":[47],"poorly":[48],"understood.":[49],"Studies":[50],"suggested":[52],"evoked":[54],"potentials":[55],"(EP)":[56],"may":[57],"be":[58,73],"used":[59],"monitor":[61],"depth":[63],"Both":[66],"transient":[67],"and":[68,91,103,114],"steady":[69],"state":[70],"responses":[71],"can":[72],"simultaneously":[74],"extracted":[75,124,142,163],"using":[76],"Continuous":[78],"Loop":[79],"Averaging":[80],"Deconvolution":[81],"(CLAD)":[82],"method":[83,120,197],"specially":[85],"designed":[86],"CLAD":[87,95,107],"sequences.":[88],"20":[89],"Hz":[90,93,101,105],"30":[92],"jittered":[94,106],"sequences":[96,108],"addition":[98],"5":[100],"isochronic":[102],"40":[104],"were":[109],"applied":[110],"baseline":[112],"awake":[113,166],"anesthesia":[116,145,183],"conditions.":[117],"A":[118],"qualitative":[119],"assess":[122],"EPs":[125,141,162],"was":[126],"developed":[127],"this":[129,192],"study,":[130],"termed":[131],"Randomized":[132],"Split":[133],"Set":[134],"Average":[135],"(RSSA).":[136],"results":[138],"showed":[139],"during":[143,164],"require":[146],"a":[147,154,172,195],"greater":[148],"number":[149],"sweeps":[151],"obtain":[153],"signal-to-noise":[155],"ratio":[156],"comparable":[157],"observed":[160],"state.":[167],"Therefore,":[168],"development":[170],"real":[173,177],"time":[174,178],"or":[175],"quasi":[176],"EP":[179,204],"monitoring":[180],"system":[181],"for":[182,198],"provides":[184],"an":[185],"increased":[186],"challenge.":[187],"RSSA":[189],"study":[193],"useful":[196],"assessing":[199],"signal":[201],"quality":[202],"responses.":[205]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}