{"id":"https://openalex.org/W1990419649","doi":"https://doi.org/10.1109/embc.2012.6346624","title":"Early detection of hemorrhage via central pulse pressure derived from a non-invasive peripheral arterial blood pressure waveform","display_name":"Early detection of hemorrhage via central pulse pressure derived from a non-invasive peripheral arterial blood pressure waveform","publication_year":2012,"publication_date":"2012-08-01","ids":{"openalex":"https://openalex.org/W1990419649","doi":"https://doi.org/10.1109/embc.2012.6346624","mag":"1990419649","pmid":"https://pubmed.ncbi.nlm.nih.gov/23366585"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2012.6346624","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346624","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079992311","display_name":"Guanqun Zhang","orcid":"https://orcid.org/0000-0002-2140-5010"},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Guanqun Zhang","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA. zhanggu2@msu.edu","Department of Electrical & Computer Engineering, Michigan State University, East Lansing, 48824 USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA. zhanggu2@msu.edu","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Electrical & Computer Engineering, Michigan State University, East Lansing, 48824 USA","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111589661","display_name":"KL Ryan","orcid":null},"institutions":[{"id":"https://openalex.org/I4210121865","display_name":"United States Army Institute of Surgical Research","ror":"https://ror.org/02gb0hd06","country_code":"US","type":"facility","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I4210121865"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. L. Ryan","raw_affiliation_strings":["United States Army Institute of Surgical Research, Fort Sam, Houston, TX, USA","United States Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA"],"affiliations":[{"raw_affiliation_string":"United States Army Institute of Surgical Research, Fort Sam, Houston, TX, USA","institution_ids":["https://openalex.org/I4210121865"]},{"raw_affiliation_string":"United States Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA","institution_ids":["https://openalex.org/I4210121865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012591267","display_name":"Caroline A. Rickards","orcid":"https://orcid.org/0000-0002-5759-6912"},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]},{"id":"https://openalex.org/I4210121865","display_name":"United States Army Institute of Surgical Research","ror":"https://ror.org/02gb0hd06","country_code":"US","type":"facility","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I4210121865"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. A. Rickards","raw_affiliation_strings":["University of Texas-San Antonio, San Antonio, TX, USA","United States Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA"],"affiliations":[{"raw_affiliation_string":"University of Texas-San Antonio, San Antonio, TX, USA","institution_ids":["https://openalex.org/I45438204"]},{"raw_affiliation_string":"United States Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA","institution_ids":["https://openalex.org/I4210121865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089261354","display_name":"V\u00edctor A. Convertino","orcid":"https://orcid.org/0000-0001-9246-0554"},"institutions":[{"id":"https://openalex.org/I4210121865","display_name":"United States Army Institute of Surgical Research","ror":"https://ror.org/02gb0hd06","country_code":"US","type":"facility","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I4210121865"]},{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V. A. Convertino","raw_affiliation_strings":["United States Army Institute of Surgical Research, Fort Sam, Houston, TX, USA","Department of Electrical & Computer Engineering, Michigan State University, East Lansing, 48824 USA"],"affiliations":[{"raw_affiliation_string":"United States Army Institute of Surgical Research, Fort Sam, Houston, TX, USA","institution_ids":["https://openalex.org/I4210121865"]},{"raw_affiliation_string":"Department of Electrical & Computer Engineering, Michigan State University, East Lansing, 48824 USA","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076698656","display_name":"Ramakrishna Mukkamala","orcid":"https://orcid.org/0000-0001-8918-4050"},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Mukkamala","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI, USA","Dept. of Electr. & Comput. Eng., Michigan State Univ., East Lansing, MI, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI, USA","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Dept. of Electr. & Comput. Eng., Michigan State Univ., East Lansing, MI, USA#TAB#","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5079992311"],"corresponding_institution_ids":["https://openalex.org/I87216513"],"apc_list":null,"apc_paid":null,"fwci":0.8068,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.71901276,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"21","issue":null,"first_page":"3116","last_page":"3119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peripheral","display_name":"Peripheral","score":0.7609796524047852},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.707838773727417},{"id":"https://openalex.org/keywords/waveform","display_name":"Waveform","score":0.6261701583862305},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.6088970899581909},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.538737952709198},{"id":"https://openalex.org/keywords/pulse-pressure","display_name":"Pulse pressure","score":0.4937034547328949},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.460276335477829},{"id":"https://openalex.org/keywords/pulse","display_name":"Pulse (music)","score":0.44057878851890564},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.15413451194763184},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.07803088426589966},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.07724529504776001}],"concepts":[{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.7609796524047852},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.707838773727417},{"id":"https://openalex.org/C197424946","wikidata":"https://www.wikidata.org/wiki/Q1165717","display_name":"Waveform","level":3,"score":0.6261701583862305},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6088970899581909},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.538737952709198},{"id":"https://openalex.org/C17140001","wikidata":"https://www.wikidata.org/wiki/Q1759415","display_name":"Pulse pressure","level":3,"score":0.4937034547328949},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.460276335477829},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.44057878851890564},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.15413451194763184},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07803088426589966},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.07724529504776001},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C554190296","wikidata":"https://www.wikidata.org/wiki/Q47528","display_name":"Radar","level":2,"score":0.0},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008150","descriptor_name":"Lower Body Negative Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008150","descriptor_name":"Lower Body Negative Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008150","descriptor_name":"Lower Body Negative Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062186","descriptor_name":"Arterial Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D062186","descriptor_name":"Arterial Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D062186","descriptor_name":"Arterial Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/embc.2012.6346624","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346624","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:23366585","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23366585","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1970748183","https://openalex.org/W2025366080","https://openalex.org/W2048499202","https://openalex.org/W2052854562","https://openalex.org/W2075327168","https://openalex.org/W2083732157","https://openalex.org/W2101379671","https://openalex.org/W2151499534","https://openalex.org/W2164524561","https://openalex.org/W2164799763","https://openalex.org/W2185029892"],"related_works":["https://openalex.org/W2383216851","https://openalex.org/W2088328627","https://openalex.org/W2073502284","https://openalex.org/W2102320489","https://openalex.org/W2127910505","https://openalex.org/W3097273220","https://openalex.org/W1979848857","https://openalex.org/W1988124167","https://openalex.org/W2072871259","https://openalex.org/W2148522477"],"abstract_inverted_index":{"There":[0],"is":[1,31,50],"a":[2,32,71,86,111],"profound":[3],"need":[4],"for":[5,61],"early":[6,41,90],"and":[7,15,38,103,110],"convenient":[8,51],"detection":[9],"of":[10,34,43,89,107,116],"hemorrhage":[11],"in":[12,76],"both":[13],"civilian":[14],"military":[16],"medicine.":[17],"Due":[18],"to":[19,52,80],"wave":[20],"reflection":[21],"timing,":[22],"central":[23,64,98],"pulse":[24],"pressure":[25,67,84],"(PP),":[26],"but":[27],"not":[28],"peripheral":[29,48,73,120],"PP,":[30],"surrogate":[33],"stroke":[35],"volume":[36],"(SV)":[37],"therefore":[39],"an":[40,56,101],"marker":[42,106],"blood":[44,66],"loss.":[45],"However,":[46],"only":[47],"PP":[49,99],"measure.":[53],"We":[54],"tested":[55],"adaptive":[57],"transfer":[58],"function":[59],"technique":[60],"deriving":[62],"the":[63,96],"arterial":[65],"(ABP)":[68],"waveform":[69,75],"from":[70],"non-invasive":[72],"ABP":[74],"healthy":[77],"humans":[78],"subjected":[79],"lower":[81],"body":[82],"negative":[83],"(LBNP),":[85],"safe":[87],"model":[88],"hemorrhage.":[91],"Our":[92],"results":[93],"showed":[94],"that":[95],"derived":[97],"provided":[100],"earlier":[102],"more":[104,113],"sensitive":[105],"progressive":[108],"LBNP":[109],"far":[112],"accurate":[114],"measure":[115],"SV":[117],"than":[118],"measured":[119],"PP.":[121]},"counts_by_year":[{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}