{"id":"https://openalex.org/W2067716465","doi":"https://doi.org/10.1109/embc.2012.6346198","title":"Electrode robustness in artificial cerebrospinal fluid for dielectrophoresis-based LoC","display_name":"Electrode robustness in artificial cerebrospinal fluid for dielectrophoresis-based LoC","publication_year":2012,"publication_date":"2012-08-01","ids":{"openalex":"https://openalex.org/W2067716465","doi":"https://doi.org/10.1109/embc.2012.6346198","mag":"2067716465","pmid":"https://pubmed.ncbi.nlm.nih.gov/23366159"},"language":"en","primary_location":{"id":"doi:10.1109/embc.2012.6346198","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346198","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058573355","display_name":"Mohamed Amine Miled","orcid":null},"institutions":[{"id":"https://openalex.org/I45683168","display_name":"Polytechnique Montr\u00e9al","ror":"https://ror.org/05f8d4e86","country_code":"CA","type":"education","lineage":["https://openalex.org/I45683168"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. A. Miled","raw_affiliation_strings":["Ecole Polytechnique de Montreal, Electrical Engineering department, Montreal, Canada. med-amine.miled@polymtl.ca","Ecole Polytechnique de Montreal, Electrical Engineering department, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ecole Polytechnique de Montreal, Electrical Engineering department, Montreal, Canada. med-amine.miled@polymtl.ca","institution_ids":["https://openalex.org/I45683168"]},{"raw_affiliation_string":"Ecole Polytechnique de Montreal, Electrical Engineering department, Canada","institution_ids":["https://openalex.org/I45683168"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082509767","display_name":"Mohamad Sawan","orcid":"https://orcid.org/0000-0002-4137-7272"},"institutions":[{"id":"https://openalex.org/I45683168","display_name":"Polytechnique Montr\u00e9al","ror":"https://ror.org/05f8d4e86","country_code":"CA","type":"education","lineage":["https://openalex.org/I45683168"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. Sawan","raw_affiliation_strings":["Electrical Engineering Department, Ecole Polytechnique de Montreal, Montreal, Canada","Ecole Polytechnique de Montreal, Electrical Engineering department, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Electrical Engineering Department, Ecole Polytechnique de Montreal, Montreal, Canada","institution_ids":["https://openalex.org/I45683168"]},{"raw_affiliation_string":"Ecole Polytechnique de Montreal, Electrical Engineering department, Canada","institution_ids":["https://openalex.org/I45683168"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4995,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.58730239,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"113","issue":null,"first_page":"1390","last_page":"1393"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dielectrophoresis","display_name":"Dielectrophoresis","score":0.8993040323257446},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.7960841655731201},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.640392541885376},{"id":"https://openalex.org/keywords/microelectrode","display_name":"Microelectrode","score":0.6244134306907654},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.5562334060668945},{"id":"https://openalex.org/keywords/microelectronics","display_name":"Microelectronics","score":0.5401642918586731},{"id":"https://openalex.org/keywords/lab-on-a-chip","display_name":"Lab-on-a-chip","score":0.5099068880081177},{"id":"https://openalex.org/keywords/cmos","display_name":"CMOS","score":0.4947337806224823},{"id":"https://openalex.org/keywords/microsystem","display_name":"Microsystem","score":0.44293156266212463},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.43678274750709534},{"id":"https://openalex.org/keywords/multielectrode-array","display_name":"Multielectrode array","score":0.42916348576545715},{"id":"https://openalex.org/keywords/microfabrication","display_name":"Microfabrication","score":0.42221567034721375},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.40561360120773315},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3979247212409973},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.1650155782699585},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.10833826661109924}],"concepts":[{"id":"https://openalex.org/C106825181","wikidata":"https://www.wikidata.org/wiki/Q902890","display_name":"Dielectrophoresis","level":3,"score":0.8993040323257446},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.7960841655731201},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.640392541885376},{"id":"https://openalex.org/C111670793","wikidata":"https://www.wikidata.org/wiki/Q16979465","display_name":"Microelectrode","level":3,"score":0.6244134306907654},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.5562334060668945},{"id":"https://openalex.org/C187937830","wikidata":"https://www.wikidata.org/wiki/Q175403","display_name":"Microelectronics","level":2,"score":0.5401642918586731},{"id":"https://openalex.org/C138942068","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Lab-on-a-chip","level":3,"score":0.5099068880081177},{"id":"https://openalex.org/C46362747","wikidata":"https://www.wikidata.org/wiki/Q173431","display_name":"CMOS","level":2,"score":0.4947337806224823},{"id":"https://openalex.org/C151054161","wikidata":"https://www.wikidata.org/wiki/Q379385","display_name":"Microsystem","level":2,"score":0.44293156266212463},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.43678274750709534},{"id":"https://openalex.org/C95967509","wikidata":"https://www.wikidata.org/wiki/Q1952355","display_name":"Multielectrode array","level":4,"score":0.42916348576545715},{"id":"https://openalex.org/C527607","wikidata":"https://www.wikidata.org/wiki/Q175538","display_name":"Microfabrication","level":4,"score":0.42221567034721375},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.40561360120773315},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3979247212409973},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1650155782699585},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10833826661109924},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002555","descriptor_name":"Cerebrospinal Fluid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004567","descriptor_name":"Electrodes, Implanted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004586","descriptor_name":"Electrophoresis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D004586","descriptor_name":"Electrophoresis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D004586","descriptor_name":"Electrophoresis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D004586","descriptor_name":"Electrophoresis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004586","descriptor_name":"Electrophoresis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004586","descriptor_name":"Electrophoresis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008839","descriptor_name":"Microelectrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D046210","descriptor_name":"Microfluidic Analytical Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1109/embc.2012.6346198","is_oa":false,"landing_page_url":"https://doi.org/10.1109/embc.2012.6346198","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society","raw_type":"proceedings-article"},{"id":"pmid:23366159","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23366159","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference","raw_type":null},{"id":"pmh:oai:publications.polymtl.ca:14959","is_oa":false,"landing_page_url":"https://publications.polymtl.ca/14959/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401013","display_name":"PolyPublie (\u00c9cole Polytechnique de Montr\u00e9al)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I45683168","host_organization_name":"Polytechnique Montr\u00e9al","host_organization_lineage":["https://openalex.org/I45683168"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Communication de conf\u00e9rence"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6","score":0.5099999904632568}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310709","display_name":"CMC Microsystems","ror":"https://ror.org/03k70ea39"},{"id":"https://openalex.org/F4320320994","display_name":"Canada Research Chairs","ror":"https://ror.org/0517h6h17"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1982275434","https://openalex.org/W1996183364","https://openalex.org/W1999743011","https://openalex.org/W2026754671","https://openalex.org/W2027880762","https://openalex.org/W2052953407","https://openalex.org/W2054362192","https://openalex.org/W2060952403","https://openalex.org/W2106006415","https://openalex.org/W2156866094"],"related_works":["https://openalex.org/W1918310741","https://openalex.org/W4302328227","https://openalex.org/W2138485117","https://openalex.org/W2169169928","https://openalex.org/W2051749269","https://openalex.org/W2004409458","https://openalex.org/W2075815377","https://openalex.org/W1988115803","https://openalex.org/W2939039077","https://openalex.org/W4296854706"],"abstract_inverted_index":{"In":[0,20],"this":[1,152],"paper,":[2],"we":[3],"present":[4],"hybrid":[5],"microelectronics":[6],"/":[7],"microfluidic":[8],"Lab-on-Chip":[9],"(LoC)":[10],"platform":[11,53],"intended":[12],"for":[13,17,107,119],"implantable":[14],"medical":[15],"microsystems":[16],"neurotransmitter":[18],"detection.":[19],"vitro":[21],"experiments":[22],"were":[23,35,113],"achieved":[24,128],"using":[25,122],"artificial":[26],"cerebrospinal":[27],"fluid":[28],"(ACSF)":[29],"from":[30],"Tocris":[31],"Bioscience":[32],"where":[33],"microspheres":[34],"immersed":[36],"to":[37,115],"test":[38],"the":[39,42,50,69,73,81,89],"behaviour":[40],"of":[41,46,49,72,80,94,135,138,141,149],"designed":[43],"LoC.":[44],"One":[45],"main":[47],"features":[48],"proposed":[51],"LoC":[52,74,127],"is":[54,66,83,92],"its":[55],"thin":[56],"thickness,":[57],"including":[58],"micro-channels":[59],"and":[60,104,146],"silicon":[61],"CMOS":[62],"chip.":[63],"The":[64,78,125],"latter":[65],"integrated":[67],"into":[68],"glass":[70],"top-layer":[71],"measuring":[75],"0.5":[76],"mm.":[77,88],"size":[79],"device":[82],"9":[84],"mm":[85],"\u00d7":[86],"5":[87],"electrode":[90,154],"architecture":[91],"composed":[93],"8\u00d72\u00d72":[95],"L-shaped":[96,111],"electrodes":[97,112],"in":[98],"a":[99,116,133,139],"650":[100],"\u00b5m":[101],"channel":[102],"width":[103],"4":[105],"sites":[106],"interdigitited":[108],"electrodes.":[109],"32":[110],"connected":[114],"electronics":[117],"circuit":[118],"cells":[120],"manipulation":[121],"dielectrophoresis":[123],"(DEP).":[124],"described":[126],"an":[129],"efficient":[130],"separation":[131],"within":[132],"concentration":[134],"50":[136],"\u00b5l":[137,148],"solution":[140],"microspheres,":[142],"distilled":[143],"water":[144],"(DW)":[145],"500":[147],"ACSF.":[150],"Beyond":[151],"concentration,":[153],"destruction":[155],"was":[156],"observed.":[157]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}