{"id":"https://openalex.org/W4200248746","doi":"https://doi.org/10.1109/dicta52665.2021.9647043","title":"Multi-stratification feature selection for diagnostic analysis of Alzheimer's disease","display_name":"Multi-stratification feature selection for diagnostic analysis of Alzheimer's disease","publication_year":2021,"publication_date":"2021-11-01","ids":{"openalex":"https://openalex.org/W4200248746","doi":"https://doi.org/10.1109/dicta52665.2021.9647043"},"language":"en","primary_location":{"id":"doi:10.1109/dicta52665.2021.9647043","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dicta52665.2021.9647043","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 Digital Image Computing: Techniques and Applications (DICTA)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100658037","display_name":"Lin Zhang","orcid":"https://orcid.org/0000-0003-1187-1015"},"institutions":[{"id":"https://openalex.org/I4210088648","display_name":"Cooperative Trials Group for Neuro-Oncology","ror":"https://ror.org/004gchq58","country_code":"AU","type":"other","lineage":["https://openalex.org/I4210088648"]},{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Lin Zhang","raw_affiliation_strings":["School of Computer Science, The University of Sydney,Camperdown,NSW,Australia","School of Computer Science, The University of Sydney, Camperdown, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, The University of Sydney,Camperdown,NSW,Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I4210088648"]},{"raw_affiliation_string":"School of Computer Science, The University of Sydney, Camperdown, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060200045","display_name":"Bowen Xin","orcid":"https://orcid.org/0000-0002-4545-9574"},"institutions":[{"id":"https://openalex.org/I4210088648","display_name":"Cooperative Trials Group for Neuro-Oncology","ror":"https://ror.org/004gchq58","country_code":"AU","type":"other","lineage":["https://openalex.org/I4210088648"]},{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Bowen Xin","raw_affiliation_strings":["School of Computer Science, The University of Sydney,Camperdown,NSW,Australia","School of Computer Science, The University of Sydney, Camperdown, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, The University of Sydney,Camperdown,NSW,Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I4210088648"]},{"raw_affiliation_string":"School of Computer Science, The University of Sydney, Camperdown, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072191207","display_name":"Shaozhen Yan","orcid":"https://orcid.org/0000-0002-0315-7930"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaozhen Yan","raw_affiliation_strings":["Xuanwu Hospital, Capital Medical University,Department of Radiology and Nuclear Medicine,Beijing,China"],"affiliations":[{"raw_affiliation_string":"Xuanwu Hospital, Capital Medical University,Department of Radiology and Nuclear Medicine,Beijing,China","institution_ids":["https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049944492","display_name":"Chaoiie Zheng","orcid":null},"institutions":[{"id":"https://openalex.org/I4210135459","display_name":"United Imaging Healthcare (China)","ror":"https://ror.org/03qqw3m37","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210135459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chaoiie Zheng","raw_affiliation_strings":["Central Research Institute, United Imaging Healthcare Group Co., Ltd,Shanghai,China,201807"],"affiliations":[{"raw_affiliation_string":"Central Research Institute, United Imaging Healthcare Group Co., Ltd,Shanghai,China,201807","institution_ids":["https://openalex.org/I4210135459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103063753","display_name":"Yun Zhou","orcid":"https://orcid.org/0000-0001-8635-4675"},"institutions":[{"id":"https://openalex.org/I4210135459","display_name":"United Imaging Healthcare (China)","ror":"https://ror.org/03qqw3m37","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210135459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Zhou","raw_affiliation_strings":["Central Research Institute, United Imaging Healthcare Group Co., Ltd,Shanghai,China,201807"],"affiliations":[{"raw_affiliation_string":"Central Research Institute, United Imaging Healthcare Group Co., Ltd,Shanghai,China,201807","institution_ids":["https://openalex.org/I4210135459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077388232","display_name":"Jie Lu","orcid":"https://orcid.org/0000-0003-0425-3921"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Lu","raw_affiliation_strings":["Xuanwu Hospital, Capital Medical University,Department of Radiology and Nuclear Medicine,Beijing,China"],"affiliations":[{"raw_affiliation_string":"Xuanwu Hospital, Capital Medical University,Department of Radiology and Nuclear Medicine,Beijing,China","institution_ids":["https://openalex.org/I183519381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046614213","display_name":"Xiuying Wang","orcid":"https://orcid.org/0000-0001-7160-5929"},"institutions":[{"id":"https://openalex.org/I4210088648","display_name":"Cooperative Trials Group for Neuro-Oncology","ror":"https://ror.org/004gchq58","country_code":"AU","type":"other","lineage":["https://openalex.org/I4210088648"]},{"id":"https://openalex.org/I129604602","display_name":"University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Xiuying Wang","raw_affiliation_strings":["School of Computer Science, The University of Sydney,Camperdown,NSW,Australia","School of Computer Science, The University of Sydney, Camperdown, NSW, Australia"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, The University of Sydney,Camperdown,NSW,Australia","institution_ids":["https://openalex.org/I129604602","https://openalex.org/I4210088648"]},{"raw_affiliation_string":"School of Computer Science, The University of Sydney, Camperdown, NSW, Australia","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5100658037"],"corresponding_institution_ids":["https://openalex.org/I129604602","https://openalex.org/I4210088648"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25288083,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":null,"first_page":"01","last_page":"07"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.707551121711731},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.6747097373008728},{"id":"https://openalex.org/keywords/region-of-interest","display_name":"Region of interest","score":0.6698073148727417},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.6600369215011597},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6310222744941711},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.5963931679725647},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5876191258430481},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.47430089116096497},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.4384254515171051},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.4279452860355377},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.32033711671829224},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1525096297264099},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15219545364379883},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.09216415882110596}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.707551121711731},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.6747097373008728},{"id":"https://openalex.org/C19609008","wikidata":"https://www.wikidata.org/wiki/Q2138203","display_name":"Region of interest","level":2,"score":0.6698073148727417},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.6600369215011597},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6310222744941711},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.5963931679725647},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5876191258430481},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.47430089116096497},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.4384254515171051},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.4279452860355377},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32033711671829224},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1525096297264099},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15219545364379883},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.09216415882110596},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/dicta52665.2021.9647043","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dicta52665.2021.9647043","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 Digital Image Computing: Techniques and Applications (DICTA)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W323404752","https://openalex.org/W2002645541","https://openalex.org/W2006096283","https://openalex.org/W2045171284","https://openalex.org/W2099892456","https://openalex.org/W2116869263","https://openalex.org/W2129473238","https://openalex.org/W2147595228","https://openalex.org/W2504526017","https://openalex.org/W2595303237","https://openalex.org/W2599451414","https://openalex.org/W2737462298","https://openalex.org/W2763355946","https://openalex.org/W2767128594","https://openalex.org/W2795578557","https://openalex.org/W2801394770","https://openalex.org/W2898391979","https://openalex.org/W2899061606","https://openalex.org/W2900422713","https://openalex.org/W2901306526","https://openalex.org/W2916168844","https://openalex.org/W2965743638","https://openalex.org/W2998216295","https://openalex.org/W2998768810","https://openalex.org/W3096804668","https://openalex.org/W4249247926","https://openalex.org/W7066667914"],"related_works":["https://openalex.org/W2327340211","https://openalex.org/W2027542625","https://openalex.org/W4292199793","https://openalex.org/W2282195379","https://openalex.org/W2089784006","https://openalex.org/W2295388821","https://openalex.org/W2102312026","https://openalex.org/W2885663991","https://openalex.org/W2071433170","https://openalex.org/W1016623679"],"abstract_inverted_index":{"In":[0],"current":[1],"neuroimaging":[2],"analysis,":[3],"feature":[4,45,172],"selection":[5,46,173],"majorly":[6],"focuses":[7],"on":[8,116,144],"analysis":[9,178],"within":[10],"single":[11],"brain":[12,18,25,51,80,113],"regions.":[13],"However,":[14],"the":[15,28,31,86,92,96,102,107,117,130,145,169,175,180],"fact":[16],"that":[17,128,168],"activities":[19],"are":[20],"usually":[21],"associated":[22],"with":[23],"multiple":[24,50],"regions":[26,52,114],"highlights":[27],"importance":[29],"of":[30,61,66,85,89,95,148],"multi-brain-region":[32],"interaction,":[33],"which":[34],"is":[35],"underexplored.":[36],"To":[37],"address":[38],"this":[39,137],"challenge,":[40],"we":[41],"propose":[42],"a":[43],"multi-stratification":[44,171],"framework":[47,59,141],"for":[48,78],"analysing":[49,83],"in":[53,136],"Magnetic":[54],"Resonance":[55],"Imaging":[56],"(MRI).":[57],"This":[58],"consists":[60],"two":[62],"major":[63],"modules:":[64],"intra-Region":[65],"Interest":[67],"(ROI)":[68],"module":[69,74,100],"and":[70,91,123,160,179],"inter-ROI":[71],"module.":[72,138],"Intra-ROI":[73],"selects":[75],"representative":[76],"features":[77,90,111,127],"each":[79],"region":[81],"by":[82],"both":[84],"statistical":[87],"difference":[88],"classifier":[93],"performance":[94,132],"candidate":[97],"subset.":[98],"Inter-ROI":[99],"employs":[101],"evaluation":[103,131],"function":[104],"to":[105,186],"guide":[106],"search,":[108],"sequentially":[109],"adding":[110],"from":[112,155],"based":[115],"corresponding":[118],"predictive":[119],"capacity.":[120],"Only":[121],"relevant":[122],"maximum":[124],"joint":[125],"significance":[126],"improve":[129],"would":[133],"be":[134],"selected":[135],"The":[139,165],"proposed":[140,170],"was":[142],"validated":[143],"diagnostic":[146],"task":[147],"Alzheimer's":[149,157],"disease.":[150],"T1-MR":[151],"images":[152],"were":[153],"collected":[154],"196":[156],"disease":[158],"patients":[159],"259":[161],"normal":[162],"control":[163],"subjects.":[164],"experiments":[166],"demonstrated":[167],"outperformed":[174],"state-of-the-art":[176],"single-brain-region":[177],"radiomics":[181],"early":[182],"integration":[183],"methods":[184],"applied":[185],"multiple-brain-region,":[187],"achieving":[188],"AUC":[189],"0.913.":[190]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
