{"id":"https://openalex.org/W4230922596","doi":"https://doi.org/10.1109/dexa.2004.1333506","title":"An efficient optimal leaf ordering for hierarchical clustering in microarray gene expression data analysis","display_name":"An efficient optimal leaf ordering for hierarchical clustering in microarray gene expression data analysis","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W4230922596","doi":"https://doi.org/10.1109/dexa.2004.1333506"},"language":"en","primary_location":{"id":"doi:10.1109/dexa.2004.1333506","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dexa.2004.1333506","pdf_url":null,"source":{"id":"https://openalex.org/S4363608686","display_name":"Proceedings. 15th International Workshop on Database and Expert Systems Applications, 2004.","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. 15th International Workshop on Database and Expert Systems Applications, 2004.","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056681421","display_name":"J. Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J. Zhang","raw_affiliation_strings":["School of Computer Science, University of Oklahama, Norman, OK, USA"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Oklahama, Norman, OK, USA","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044800372","display_name":"L. Gruenwald","orcid":null},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Gruenwald","raw_affiliation_strings":["School of Computer Science, University of Oklahama, Norman, OK, USA"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Oklahama, Norman, OK, USA","institution_ids":["https://openalex.org/I8692664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5056681421"],"corresponding_institution_ids":["https://openalex.org/I8692664"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.38496583,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"396","last_page":"400"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10796","display_name":"Cooperative Communication and Network Coding","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1705","display_name":"Computer Networks and Communications"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.988099992275238,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.7042946219444275},{"id":"https://openalex.org/keywords/hierarchical-clustering","display_name":"Hierarchical clustering","score":0.6573593020439148},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.604307234287262},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5301675796508789},{"id":"https://openalex.org/keywords/binary-number","display_name":"Binary number","score":0.5081169605255127},{"id":"https://openalex.org/keywords/binary-data","display_name":"Binary data","score":0.4723930060863495},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.45852819085121155},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.442910373210907},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.42777836322784424},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.42273035645484924},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3659212589263916},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.34635043144226074},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.32551029324531555},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.27136728167533875},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.23952370882034302},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.21435043215751648}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.7042946219444275},{"id":"https://openalex.org/C92835128","wikidata":"https://www.wikidata.org/wiki/Q1277447","display_name":"Hierarchical clustering","level":3,"score":0.6573593020439148},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.604307234287262},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5301675796508789},{"id":"https://openalex.org/C48372109","wikidata":"https://www.wikidata.org/wiki/Q3913","display_name":"Binary number","level":2,"score":0.5081169605255127},{"id":"https://openalex.org/C2779190172","wikidata":"https://www.wikidata.org/wiki/Q4913888","display_name":"Binary data","level":3,"score":0.4723930060863495},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.45852819085121155},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.442910373210907},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.42777836322784424},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42273035645484924},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3659212589263916},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.34635043144226074},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.32551029324531555},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27136728167533875},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.23952370882034302},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21435043215751648},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C94375191","wikidata":"https://www.wikidata.org/wiki/Q11205","display_name":"Arithmetic","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/dexa.2004.1333506","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dexa.2004.1333506","pdf_url":null,"source":{"id":"https://openalex.org/S4363608686","display_name":"Proceedings. 15th International Workshop on Database and Expert Systems Applications, 2004.","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. 15th International Workshop on Database and Expert Systems Applications, 2004.","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W2079966248","https://openalex.org/W2087684630","https://openalex.org/W2103453943","https://openalex.org/W2143326696","https://openalex.org/W2147246240","https://openalex.org/W2151202196"],"related_works":["https://openalex.org/W2154693897","https://openalex.org/W2018164323","https://openalex.org/W1980535114","https://openalex.org/W2094988397","https://openalex.org/W2083580028","https://openalex.org/W2165713005","https://openalex.org/W2063706985","https://openalex.org/W2380155140","https://openalex.org/W2055644595","https://openalex.org/W4233766581"],"abstract_inverted_index":{"The":[0,21],"objective":[1],"of":[2],"This":[3],"work":[4],"is":[5,44],"to":[6,36],"derive":[7],"an":[8],"efficient":[9,45],"and":[10,46],"optimal":[11],"ordering":[12],"method":[13,23],"for":[14],"genes":[15],"produced":[16],"by":[17],"binary":[18],"hierarchical":[19],"clustering.":[20],"proposed":[22,39,42],"examines":[24],"all":[25],"possible":[26],"2/sup":[27],"n-1/":[28],"orderings":[29],"in":[30],"O(n/sup":[31],"2/)":[32],"time":[33],"complexity.":[34],"Compared":[35],"the":[37],"previously":[38],"methods,":[40],"our":[41],"solution":[43],"optimal.":[47]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}