{"id":"https://openalex.org/W2133818367","doi":"https://doi.org/10.1109/dexa.2003.1231990","title":"An algorithm for generating representative functional annotations based on Gene Ontology","display_name":"An algorithm for generating representative functional annotations based on Gene Ontology","publication_year":2004,"publication_date":"2004-01-24","ids":{"openalex":"https://openalex.org/W2133818367","doi":"https://doi.org/10.1109/dexa.2003.1231990","mag":"2133818367"},"language":"en","primary_location":{"id":"doi:10.1109/dexa.2003.1231990","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dexa.2003.1231990","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"14th International Workshop on Database and Expert Systems Applications, 2003. Proceedings.","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005901379","display_name":"In-Yee Lee","orcid":"https://orcid.org/0000-0003-2090-7083"},"institutions":[{"id":"https://openalex.org/I4210098366","display_name":"Institute of Information Science, Academia Sinica","ror":"https://ror.org/00z83z196","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210098366","https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"In-Yee Lee","raw_affiliation_strings":["Institute of Information Science, Academia Sinica, Taipei, Taiwan","Intstitute of Inf. Sci., Acad. Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Information Science, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210098366"]},{"raw_affiliation_string":"Intstitute of Inf. Sci., Acad. Sinica, Taipei, Taiwan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051317071","display_name":"Jan-Ming Ho","orcid":"https://orcid.org/0000-0002-2432-8233"},"institutions":[{"id":"https://openalex.org/I4210098366","display_name":"Institute of Information Science, Academia Sinica","ror":"https://ror.org/00z83z196","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210098366","https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Jan-Ming Ho","raw_affiliation_strings":["Institute of Information Science, Academia Sinica, Taipei, Taiwan","Intstitute of Inf. Sci., Acad. Sinica, Taipei, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Information Science, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210098366"]},{"raw_affiliation_string":"Intstitute of Inf. Sci., Acad. Sinica, Taipei, Taiwan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017714504","display_name":"Wen\u2010chang Lin","orcid":"https://orcid.org/0000-0003-0194-1745"},"institutions":[{"id":"https://openalex.org/I4210098366","display_name":"Institute of Information Science, Academia Sinica","ror":"https://ror.org/00z83z196","country_code":"TW","type":"facility","lineage":["https://openalex.org/I4210098366","https://openalex.org/I84653119"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Wen-Chang Lin","raw_affiliation_strings":["Institute of Information Science, Academia Sinica, Taipei, Taiwan","Academia Sinica )"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Information Science, Academia Sinica, Taipei, Taiwan","institution_ids":["https://openalex.org/I4210098366"]},{"raw_affiliation_string":"Academia Sinica )","institution_ids":["https://openalex.org/I84653119"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7236,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.68569434,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":null,"first_page":"10","last_page":"15"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.8008217811584473},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7514275312423706},{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene ontology","score":0.5967881679534912},{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.5429785251617432},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.5358269214630127},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.4965553879737854},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.491608202457428},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.4795815050601959},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.47368741035461426},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.360210120677948},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.33633512258529663},{"id":"https://openalex.org/keywords/natural-language-processing","display_name":"Natural language processing","score":0.3210615813732147},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.31608060002326965},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.24315404891967773},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.1676793396472931},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.09460562467575073},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09247472882270813}],"concepts":[{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.8008217811584473},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7514275312423706},{"id":"https://openalex.org/C2987395477","wikidata":"https://www.wikidata.org/wiki/Q135085","display_name":"Gene ontology","level":4,"score":0.5967881679534912},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.5429785251617432},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.5358269214630127},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.4965553879737854},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.491608202457428},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.4795815050601959},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.47368741035461426},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.360210120677948},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.33633512258529663},{"id":"https://openalex.org/C204321447","wikidata":"https://www.wikidata.org/wiki/Q30642","display_name":"Natural language processing","level":1,"score":0.3210615813732147},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.31608060002326965},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.24315404891967773},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1676793396472931},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.09460562467575073},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09247472882270813},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/dexa.2003.1231990","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dexa.2003.1231990","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"14th International Workshop on Database and Expert Systems Applications, 2003. Proceedings.","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education","score":0.7200000286102295}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1597538863","https://openalex.org/W1975796937","https://openalex.org/W2023494101","https://openalex.org/W2055043387","https://openalex.org/W2099393019","https://openalex.org/W2104191104","https://openalex.org/W2106093878","https://openalex.org/W2122536624","https://openalex.org/W2133045719","https://openalex.org/W2148853951","https://openalex.org/W2150261709","https://openalex.org/W2150313163","https://openalex.org/W2153294290","https://openalex.org/W2160521949","https://openalex.org/W2162510285","https://openalex.org/W2163500926","https://openalex.org/W2164429509","https://openalex.org/W2169382386","https://openalex.org/W4236236547","https://openalex.org/W4236241609","https://openalex.org/W4246066782"],"related_works":["https://openalex.org/W2361861616","https://openalex.org/W2263699433","https://openalex.org/W2377979023","https://openalex.org/W2218034408","https://openalex.org/W2392921965","https://openalex.org/W2358755282","https://openalex.org/W2625833328","https://openalex.org/W1533177136","https://openalex.org/W2251519152","https://openalex.org/W4380994516"],"abstract_inverted_index":{"The":[0],"authors":[1],"address":[2],"the":[3,50,73,83,95,100,114,129],"issue":[4],"of":[5,28,53,77,88,91,116,133],"providing":[6],"highly":[7],"representative":[8,63,135],"descriptions":[9],"in":[10],"automated":[11,109],"functional":[12,117,138],"annotations.":[13,45,64,139],"For":[14],"an":[15,108],"uncharacterized":[16],"sequence,":[17],"a":[18,58,67,78],"common":[19],"strategy":[20,40],"is":[21,131],"to":[22,42,61,125],"infer":[23],"such":[24],"annotations":[25,118],"from":[26],"those":[27],"well-characterized":[29],"sequences":[30],"that":[31,70,112],"contain":[32],"its":[33],"homologues.":[34],"However,":[35],"under":[36],"many":[37],"circumstances,":[38],"this":[39],"fails":[41],"produce":[43],"meaningful":[44,137],"Using":[46],"information":[47],"revealed":[48],"by":[49],"structured":[51],"vocabularies":[52],"Gene":[54],"ontology,":[55],"we":[56],"propose":[57],"quantitative":[59],"algorithm":[60,101,130],"assign":[62],"We":[65,98],"established":[66],"confidence":[68],"function":[69],"reflects":[71],"both":[72],"precision":[74],"and":[75,81,136],"coverage":[76],"candidate":[79,92],"annotation,":[80],"reasoned":[82],"function's":[84],"parameters":[85],"form":[86],"analyses":[87],"significant":[89],"forms":[90],"distributions":[93],"on":[94],"GO":[96],"graph.":[97],"tested":[99],"with":[102],"our":[103,126],"self-designed":[104],"BIO101":[105],"(http:":[106],"//BIO101.iis.sinica.edu.tw),":[107],"annotation":[110],"system":[111],"supports":[113],"workflows":[115],"for":[119],"expressed":[120],"sequence":[121],"tags":[122],"(ESTs).":[123],"According":[124],"experimental":[127],"results,":[128],"capable":[132],"producing":[134]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}