{"id":"https://openalex.org/W4404955687","doi":"https://doi.org/10.1109/dcis62603.2024.10769121","title":"Integrated Electrode-Based Systems for Stem-Cell Stimulation","display_name":"Integrated Electrode-Based Systems for Stem-Cell Stimulation","publication_year":2024,"publication_date":"2024-11-13","ids":{"openalex":"https://openalex.org/W4404955687","doi":"https://doi.org/10.1109/dcis62603.2024.10769121"},"language":"en","primary_location":{"id":"doi:10.1109/dcis62603.2024.10769121","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dcis62603.2024.10769121","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 39th Conference on Design of Circuits and Integrated Systems (DCIS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114286160","display_name":"A. Algar\u00edn","orcid":null},"institutions":[{"id":"https://openalex.org/I79238269","display_name":"Universidad de Sevilla","ror":"https://ror.org/03yxnpp24","country_code":"ES","type":"education","lineage":["https://openalex.org/I79238269"]},{"id":"https://openalex.org/I4210104545","display_name":"Instituto de Microelectr\u00f3nica de Sevilla","ror":"https://ror.org/01mqtzm43","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210104545","https://openalex.org/I4210147934","https://openalex.org/I79238269"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"A. Algarin","raw_affiliation_strings":["Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain"],"affiliations":[{"raw_affiliation_string":"Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain","institution_ids":["https://openalex.org/I4210104545","https://openalex.org/I79238269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088174722","display_name":"David E. Martin","orcid":"https://orcid.org/0000-0003-2820-5983"},"institutions":[{"id":"https://openalex.org/I79238269","display_name":"Universidad de Sevilla","ror":"https://ror.org/03yxnpp24","country_code":"ES","type":"education","lineage":["https://openalex.org/I79238269"]},{"id":"https://openalex.org/I4210104545","display_name":"Instituto de Microelectr\u00f3nica de Sevilla","ror":"https://ror.org/01mqtzm43","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210104545","https://openalex.org/I4210147934","https://openalex.org/I79238269"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"D. Mart\u00edn","raw_affiliation_strings":["Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain"],"affiliations":[{"raw_affiliation_string":"Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain","institution_ids":["https://openalex.org/I4210104545","https://openalex.org/I79238269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023641163","display_name":"Paula Daza","orcid":"https://orcid.org/0000-0001-5170-1868"},"institutions":[{"id":"https://openalex.org/I79238269","display_name":"Universidad de Sevilla","ror":"https://ror.org/03yxnpp24","country_code":"ES","type":"education","lineage":["https://openalex.org/I79238269"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"P. Daza","raw_affiliation_strings":["Universidad de Sevilla,Biology Faculty,Dpto. Cell Biology,Sevilla,Spain"],"affiliations":[{"raw_affiliation_string":"Universidad de Sevilla,Biology Faculty,Dpto. Cell Biology,Sevilla,Spain","institution_ids":["https://openalex.org/I79238269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073688627","display_name":"Gloria Huertas","orcid":"https://orcid.org/0000-0001-5851-2576"},"institutions":[{"id":"https://openalex.org/I4210104545","display_name":"Instituto de Microelectr\u00f3nica de Sevilla","ror":"https://ror.org/01mqtzm43","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210104545","https://openalex.org/I4210147934","https://openalex.org/I79238269"]},{"id":"https://openalex.org/I79238269","display_name":"Universidad de Sevilla","ror":"https://ror.org/03yxnpp24","country_code":"ES","type":"education","lineage":["https://openalex.org/I79238269"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"G. Huertas","raw_affiliation_strings":["Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain"],"affiliations":[{"raw_affiliation_string":"Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain","institution_ids":["https://openalex.org/I4210104545","https://openalex.org/I79238269"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080209850","display_name":"Alberto Y\u00fafera","orcid":"https://orcid.org/0000-0002-1814-6089"},"institutions":[{"id":"https://openalex.org/I79238269","display_name":"Universidad de Sevilla","ror":"https://ror.org/03yxnpp24","country_code":"ES","type":"education","lineage":["https://openalex.org/I79238269"]},{"id":"https://openalex.org/I4210104545","display_name":"Instituto de Microelectr\u00f3nica de Sevilla","ror":"https://ror.org/01mqtzm43","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210104545","https://openalex.org/I4210147934","https://openalex.org/I79238269"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A. Y\u00fafera","raw_affiliation_strings":["Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain"],"affiliations":[{"raw_affiliation_string":"Instituto de Microelectrónica de Sevilla-Universidad de Sevilla (IMSE-US),Sevilla,Spain","institution_ids":["https://openalex.org/I4210104545","https://openalex.org/I79238269"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5114286160"],"corresponding_institution_ids":["https://openalex.org/I4210104545","https://openalex.org/I79238269"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23870413,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13052","display_name":"Molecular Communication and Nanonetworks","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stem-cell","display_name":"Stem cell","score":0.5051091313362122},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.49404028058052063},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.4622570872306824},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.43273961544036865},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.32535913586616516},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.1853017807006836},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.1846260130405426},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.18345016241073608},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1521686315536499}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5051091313362122},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.49404028058052063},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.4622570872306824},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.43273961544036865},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.32535913586616516},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1853017807006836},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1846260130405426},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.18345016241073608},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1521686315536499},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/dcis62603.2024.10769121","is_oa":false,"landing_page_url":"https://doi.org/10.1109/dcis62603.2024.10769121","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 39th Conference on Design of Circuits and Integrated Systems (DCIS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.41999998688697815,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1511389583","https://openalex.org/W2023005559","https://openalex.org/W2034457588","https://openalex.org/W2039819334","https://openalex.org/W2040793024","https://openalex.org/W2061793163","https://openalex.org/W2065487734","https://openalex.org/W2080039251","https://openalex.org/W2084344892","https://openalex.org/W2089594236","https://openalex.org/W2098606699","https://openalex.org/W2108571485","https://openalex.org/W2142309273","https://openalex.org/W2142894335","https://openalex.org/W2153787766","https://openalex.org/W2159421177","https://openalex.org/W2167589820","https://openalex.org/W2180930892","https://openalex.org/W2513906510","https://openalex.org/W2575060568","https://openalex.org/W2609008982","https://openalex.org/W2767261845","https://openalex.org/W2892271309","https://openalex.org/W2901622301","https://openalex.org/W2908573463","https://openalex.org/W2981132661","https://openalex.org/W3137752260","https://openalex.org/W3174721744","https://openalex.org/W3199155830","https://openalex.org/W4310335127","https://openalex.org/W4388941891","https://openalex.org/W4391232122"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2016187641","https://openalex.org/W4404725684","https://openalex.org/W2805339068","https://openalex.org/W4246450666","https://openalex.org/W4388998267","https://openalex.org/W2898370298","https://openalex.org/W2137437058"],"abstract_inverted_index":{"This":[0,234],"paper":[1],"is":[2,84,96,102,109],"conceived":[3],"as":[4,136,202],"an":[5,66],"update":[6],"of":[7,54,153,179,246,252],"integrated":[8,219,244],"electrode-based":[9],"systems":[10],"involved":[11],"on":[12,19,218,242],"Stem":[13],"Cells":[14],"(SC)":[15],"differentiation":[16,175],"processes":[17,63],"based":[18],"electric":[20,56,207],"stimulation,":[21],"actual":[22],"and":[23,33,73,158,163,190,225,228],"future":[24],"progress.":[25],"These":[26],"techniques":[27],"are":[28,199],"applied":[29,93],"in":[30,88,126],"different":[31],"biological":[32,62],"medical":[34],"protocols":[35],"with":[36],"varied":[37],"objectives:":[38],"cell":[39,48,71,77,82,101,121,130,171,210,253],"linage":[40],"derivation,":[41],"tissue":[42],"engineering,":[43],"cellular":[44],"therapy,":[45],"cancer":[46],"research,":[47],"motility,":[49],"etc.":[50],"The":[51,195],"general":[52],"procedure":[53],"SC":[55],"stimulation":[57,180],"tries":[58],"to":[59,69,74,79,91,138,148,161,205,209,238],"emulate":[60],"the":[61,70,76,92,100,112,120,129,139,154,165,185,191,200,226,249],"by":[64,231],"applying":[65],"electrical":[67,140],"signal":[68],"culture,":[72],"evaluate":[75],"response":[78,137],"it.":[80],"Basically,":[81],"metabolism":[83,131],"electrically":[85],"sensitive,":[86],"answering":[87],"some":[89,127],"way":[90,128],"stimuli.":[94],"What":[95],"really":[97],"happening":[98],"at":[99,119,170,248],"not":[103],"well":[104],"known":[105],"actually,":[106],"but":[107],"it":[108],"clear":[110],"that":[111,173],"ion":[113],"density":[114],"changes,":[115],"positive":[116],"or":[117,168],"negative,":[118],"membrane":[122],"neighbourhood":[123],"must":[124],"excite":[125],"(receptors)":[132],"activating":[133],"its":[134,232],"\u201cdifferentiation\u201d":[135],"stimulus.":[141],"In":[142],"this":[143,240],"review,":[144],"we":[145,213],"will":[146,182,214,236],"try":[147],"progress":[149],"towards":[150],"a":[151],"compilation":[152],"proposed":[155],"system":[156],"setups,":[157],"specifications":[159,229],"required,":[160],"find":[162],"know":[164],"local":[166],"conditions":[167],"variables":[169],"environment":[172],"activate":[174],"processes.":[176],"Two":[177],"features":[178],"(STI)":[181],"be":[183],"reviewed:":[184],"setup":[186],"employed":[187],"for":[188,193],"STI;":[189],"circuits":[192],"STI.":[194],"nexus":[196],"between":[197],"both":[198],"electrodes,":[201,247],"required":[203],"interfaces":[204],"apply":[206],"signals":[208],"cultures;":[211],"so":[212],"focus":[215],"our":[216],"interest":[217],"Micro-Electrode":[220],"Arrays":[221],"(MEAs)":[222],"realizations":[223],"mainly,":[224],"problems":[227],"imposed":[230],"use.":[233],"approach":[235],"allow":[237],"centre":[239],"review":[241],"fully":[243],"realization":[245],"same":[250],"scale":[251],"sizes.":[254]},"counts_by_year":[],"updated_date":"2025-12-27T23:08:20.325037","created_date":"2025-10-10T00:00:00"}