{"id":"https://openalex.org/W1854934245","doi":"https://doi.org/10.1109/csb.2003.1227407","title":"Genetic algorithm approach for the closest string problem","display_name":"Genetic algorithm approach for the closest string problem","publication_year":2004,"publication_date":"2004-03-30","ids":{"openalex":"https://openalex.org/W1854934245","doi":"https://doi.org/10.1109/csb.2003.1227407","mag":"1854934245"},"language":"en","primary_location":{"id":"doi:10.1109/csb.2003.1227407","is_oa":false,"landing_page_url":"https://doi.org/10.1109/csb.2003.1227407","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005674714","display_name":"Holger Mauch","orcid":null},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"H. Mauch","raw_affiliation_strings":["Department of Information and Computer Science, University of Hawaii, Manoa, Honolulu, HI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Information and Computer Science, University of Hawaii, Manoa, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066896606","display_name":"Michael J. Melzer","orcid":"https://orcid.org/0000-0003-0390-3857"},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.J. Melzer","raw_affiliation_strings":["Department of Plant and Environmental Protection Sciences, University of Hawaii, Manoa, Honolulu, HI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Protection Sciences, University of Hawaii, Manoa, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034267754","display_name":"Jilei Hu","orcid":"https://orcid.org/0000-0003-4673-0845"},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.S. Hu","raw_affiliation_strings":["Department of Plant and Environmental Protection Sciences, University of Hawaii, Manoa, Honolulu, HI, USA"],"affiliations":[{"raw_affiliation_string":"Department of Plant and Environmental Protection Sciences, University of Hawaii, Manoa, Honolulu, HI, USA","institution_ids":["https://openalex.org/I117965899"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005674714"],"corresponding_institution_ids":["https://openalex.org/I117965899"],"apc_list":null,"apc_paid":null,"fwci":0.4497,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.73521775,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"560","last_page":"561"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12326","display_name":"Network Packet Processing and Optimization","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1708","display_name":"Hardware and Architecture"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6246821880340576},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.5124354958534241},{"id":"https://openalex.org/keywords/string","display_name":"String (physics)","score":0.5073074698448181},{"id":"https://openalex.org/keywords/genetic-algorithm","display_name":"Genetic algorithm","score":0.4654252231121063},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.23498818278312683},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.12492892146110535}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6246821880340576},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5124354958534241},{"id":"https://openalex.org/C157486923","wikidata":"https://www.wikidata.org/wiki/Q1376436","display_name":"String (physics)","level":2,"score":0.5073074698448181},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.4654252231121063},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.23498818278312683},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.12492892146110535},{"id":"https://openalex.org/C37914503","wikidata":"https://www.wikidata.org/wiki/Q156495","display_name":"Mathematical physics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/csb.2003.1227407","is_oa":false,"landing_page_url":"https://doi.org/10.1109/csb.2003.1227407","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1497256448","https://openalex.org/W1574380692","https://openalex.org/W1661448904","https://openalex.org/W2039555480","https://openalex.org/W2047386086","https://openalex.org/W2077595184","https://openalex.org/W3023540311","https://openalex.org/W4236055811"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2051487156","https://openalex.org/W2073681303","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W4391913857"],"abstract_inverted_index":{"A":[0],"fundamental":[1],"aspect":[2],"of":[3,15,99,120,134,144],"post-transcriptional":[4],"gene":[5],"silencing":[6],"(PTGS)":[7],"or":[8,23,129],"RNA":[9],"interference":[10],"(RNAi)":[11],"is":[12,61,139,161],"the":[13,19,47,51,69,100,132,137,142,166],"requirement":[14],"sequence":[16,44,66,70,86],"homology":[17,96],"between":[18],"transgene":[20,52],"and":[21],"viral":[22,75,101],"messenger":[24],"RNAs":[25],"being":[26],"targeted.":[27],"For":[28],"example,":[29],"virus-resistant":[30],"transgenic":[31],"plants":[32],"are":[33,39],"resistant":[34],"only":[35],"to":[36,46,62,97,123,140,164],"viruses":[37],"that":[38,67,173],"closely":[40],"related":[41],"(i.e.":[42],"high":[43],"homology)":[45],"virus":[48],"from":[49],"which":[50,81],"was":[53],"derived.":[54],"One":[55],"idea":[56],"for":[57],"broadening":[58],"this":[59,112,115,159,174],"resistance":[60],"devise":[63],"an":[64,79,84,88],"artificial":[65,85],"incorporates":[68],"variation":[71],"found":[72],"in":[73,103,111],"a":[74,93,104,145,183],"population.":[76,105],"This":[77],"requires":[78],"algorithm":[80,108],"can":[82,178],"determine":[83],"with":[87,182],"optimal":[89],"(or":[90],"at":[91],"least":[92],"90-95%":[94],")":[95],"all":[98,124],"sequences":[102],"The":[106],"genetic":[107],"(GA)":[109],"presented":[110],"paper":[113],"serves":[114],"purpose.":[116],"It":[117],"should":[118],"be":[119,179],"great":[121],"value":[122],"researchers":[125],"who":[126],"utilize":[127],"PTGS":[128],"RNAi.":[130],"In":[131,156],"context":[133],"coding":[135],"theory,":[136],"task":[138],"find":[141],"radius":[143],"code":[146],"S":[147],"/spl":[148],"sub/":[149],"{A,":[150],"C,":[151],"G,":[152],"T}":[153],"/sup":[154],"n/.":[155],"computational":[157],"biology":[158],"problem":[160,177],"commonly":[162],"referred":[163],"as":[165],"closest":[167],"string":[168],"problem.":[169],"Experimental":[170],"results":[171],"suggest":[172],"NP-complete":[175],"optimization":[176],"approached":[180],"well":[181],"custom-built":[184],"GA.":[185]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}